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Quinapril/Hydrochlorothiazide Tablet shortage

Quinapril/Hydrochlorothiazide Tablet is currently listed in shortage by the FDA. The FDA lists 6 affected products. The reported reason: Discontinuation of the manufacture of the drug. This page was last refreshed from FDA data on Oct 3, 2026.

Current ⚠ Supply risk: High Cardiovascular 6 products 2 manufacturers 1,354 days · 3.7 yr First posted Jan 19, 2023 Updated Sep 15, 2026
Here’s the bottom line

Aurobindo Pharma USA is stopping its quinapril/hydrochlorothiazide tablets, and this change may be permanent. The same medicine is still listed by other manufacturers, including Lupin Pharmaceuticals and Cipla USA, so supply exists from sources not reporting a shortage.

Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers (see options) and your prescriber about a long-term plan.

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
6
Affected NDCs
2
Reporting manufacturers
1/2
Reporting mfrs supplying
3/3
Affected strengths supplied
50%
NDCs unavailable
1,354
Days in shortage
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 3, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Quinapril/Hydrochlorothiazide Tablet. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
6 NDCs
Available 3 Unavailable 3
Affected strengths still supplied
Among manufacturers reporting this shortage
3/3 strengths
Sourceable 3
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
1/2 makers
With supply 1 No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Quinapril/Hydrochlorothiazide Tablet from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Lupin Pharmaceuticals,Inc. Aurobindo Pharma Limited Cipla USA Inc.
See all other options & details →
Shortage timeline
  1. Sep 15, 2026
    Currently in shortage
    6 of 6 products affected.
  2. Jun 2, 2026
    FDA refreshed this shortage record
    3 products updated.
  3. Jan 19, 2023
    First reported to the FDA
    6 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Aurobindo Pharma USA 📞 866-850-2876 3 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Quinapril Hydrochloride And Hydrochlorothiazide, Tablet, 12.5 mg; 10 mg (NDC 65862-161-90) NDC 65862-0161-90 — Unavailable Discontinuation of the manufacture of the drug Discontinuation of the manufacture of the drug
Current Quinapril Hydrochloride And Hydrochlorothiazide, Tablet, 25 mg; 20 mg (NDC 65862-163-90) NDC 65862-0163-90 — Unavailable Discontinuation of the manufacture of the drug Discontinuation of the manufacture of the drug
Current Quinapril Hydrochloride And Hydrochlorothiazide, Tablet, 12.5 mg; 20 mg (NDC 65862-162-90) NDC 65862-0162-90 — Unavailable Discontinuation of the manufacture of the drug Discontinuation of the manufacture of the drug
Manufacturer: Chartwell Molecular Holdings LLC 📞 845-268-5000 x 510 or Chartwell Customer service at [email protected] 3 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Quinapril/Hydrochlorothiazide, Tablet, 12.5 mg; 20 mg (NDC 62135-668-90) NDC 62135-0668-90 — Available — —
Current Quinapril/Hydrochlorothiazide, Tablet, 12.5 mg; 10 mg (NDC 62135-667-90) NDC 62135-0667-90 — Available — —
Current Quinapril/Hydrochlorothiazide, Tablet, 25 mg; 20 mg (NDC 62135-669-90) NDC 62135-0669-90 — Available — —

These rows are manufacturer reports to the FDA for Quinapril/Hydrochlorothiazide Tablet — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Quinapril/Hydrochlorothiazide Tablet? options further down this page.

Why is Quinapril/Hydrochlorothiazide Tablet in shortage?

Aurobindo Pharma has permanently stopped making all three strengths of their quinapril/hydrochlorothiazide tablets — the 10 mg/12.5 mg, 20 mg/12.5 mg, and 20 mg/25 mg combinations (all in 90-count bottles). This isn't a temporary factory delay or a supply hiccup — they've made the decision to discontinue manufacturing these products entirely, which is why they show up on the FDA shortage list.

It's worth knowing that this report covers only Aurobindo's products. Chartwell Molecular Holdings is a separate manufacturer, and according to this FDA report, all three of those same strengths under their label are currently listed as available.

FDA reason code(s): Discontinuation of the manufacture of the drug

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Quinapril/Hydrochlorothiazide Tablet, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Quinapril/Hydrochlorothiazide Tablet?

Quinapril/hydrochlorothiazide, the combination tablet used to help manage blood pressure, is currently on the FDA shortage list. I want to walk you through what that means so you can find the strength you take.

All three strengths — 10 mg/12.5 mg, 20 mg/12.5 mg, and 20 mg/25 mg — still have an available source. One manufacturer (Aurobindo Pharma USA) has reported it is discontinuing its versions of these tablets, so about half of the listed products are marked unavailable. However, another maker, Chartwell, is still reporting all three strengths as available. So even though one company is stepping away, the medicine itself is still being supplied.

Please keep taking your medicine as prescribed. Here is how to approach this:

  • Do not stop, skip, or change your dose on your own.
  • Ask your pharmacy to order your strength; pharmacies can check wholesalers and other manufacturers (such as Chartwell's available stock).
  • The same medicine is also made by Lupin, Cipla, and Aurobindo — your pharmacy may be able to source one of these, though it may not be in local stock.
  • If your exact tablet cannot be found, ask your prescriber or pharmacist about options, such as a different strength or a clinician-chosen alternative.

Manufacturer contact numbers are listed on this page for reference, though pharmacies usually handle those calls. This is national data and may not match your local pharmacy's actual stock.

See “Where else can I get Quinapril/Hydrochlorothiazide Tablet?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.

Where else can I get Quinapril/Hydrochlorothiazide Tablet?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Quinapril/Hydrochlorothiazide Tablet is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Quinapril Hcl And Hydrochlorothiazide QUINAPRIL HYDROCHLORIDE 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 Tablet · Oral Lupin Pharmaceuticals,Inc. 43386-0710-05
Quinapril Hcl And Hydrochlorothiazide QUINAPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 Tablet · Oral Lupin Pharmaceuticals,Inc. 43386-0711-05
Quinapril Hcl And Hydrochlorothiazide QUINAPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 Tablet · Oral Lupin Pharmaceuticals,Inc. 43386-0712-05
Quinapril Hydrochloride/Hydrochlorothiazide QUINAPRIL HYDROCHLORIDE 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 Tablet, Film Coated · Oral Aurobindo Pharma Limited 65862-0161-71
Quinapril Hydrochloride/Hydrochlorothiazide QUINAPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 Tablet, Film Coated · Oral Aurobindo Pharma Limited 65862-0162-30
Quinapril Hydrochloride/Hydrochlorothiazide QUINAPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 Tablet, Film Coated Aurobindo Pharma Limited 65862-0163-59
Quinapril And Hydrochlorothiazide 10/12.5 QUINAPRIL HYDROCHLORIDE 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 Tablet · Oral Cipla USA Inc. 69097-0828-05
Quinapril And Hydrochlorothiazide 20/12.5 QUINAPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 Tablet · Oral Cipla USA Inc. 69097-0829-05
Quinapril And Hydrochlorothiazide 20/25 QUINAPRIL HYDROCHLORIDE 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 Tablet · Oral Cipla USA Inc. 69097-0831-05
Therapeutic equivalents & pricing 12 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Quinapril Hydrochloride/Hydrochlorothiazide 10 mg/1; 12.5 mgNDC 65862-0161-90 Aurobindo 90 tablets $0.312 AB FDA listed
Quinapril Hydrochloride/Hydrochlorothiazide 20 mg/1; 25 mgNDC 65862-0163-90 Aurobindo 90 tablets $0.345 — FDA listed
Quinapril Hydrochloride/Hydrochlorothiazide 20 mg/1; 12.5 mgNDC 65862-0162-90 Aurobindo 90 tablets $0.361 AB FDA listed
Quinapril HCL and Hydrochlorothiazide 10 mg/1; 12.5 mgNDC 43386-0710-03 Lupin 30 tablets — AB FDA listed
Quinapril and Hydrochlorothiazide 10 mg/1; 12.5 mgNDC 62135-0667-90 Chartwell 90 tablets — AB FDA listed
Quinapril and Hydrochlorothiazide 10/12.5 10 mg/1; 12.5 mgNDC 69097-0828-05 Cipla 90 tablets — — FDA listed
Quinapril HCL and Hydrochlorothiazide 20 mg/1; 25 mgNDC 43386-0712-03 Lupin 30 tablets — AB FDA listed
Quinapril and Hydrochlorothiazide 20 mg/1; 25 mgNDC 62135-0669-90 Chartwell 90 tablets — AB FDA listed
Quinapril and Hydrochlorothiazide 20/25 20 mg/1; 25 mgNDC 69097-0831-05 Cipla 90 tablets — — FDA listed
Quinapril HCL and Hydrochlorothiazide 20 mg/1; 12.5 mgNDC 43386-0711-03 Lupin 30 tablets — AB FDA listed
Quinapril and Hydrochlorothiazide 20 mg/1; 12.5 mgNDC 62135-0668-90 Chartwell 90 tablets — AB FDA listed
Quinapril and Hydrochlorothiazide 20/12.5 20 mg/1; 12.5 mgNDC 69097-0829-05 Cipla 90 tablets — — FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Quinapril/Hydrochlorothiazide Tablet — that fall in the same broad treatment class (ace inhibitor-thiazide or thiazide-like diuretic) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 019140
GCN 54160
HICL code 007826
Ingredient (HICL) Quinapril/Hydrochlorothiazide
HIC1 code A
Therapeutic class — broad (HIC1) Cardiovascular System
HIC2 code A4
Therapeutic class — intermediate (HIC2) Antihypertensives
HIC3 code A4J
Therapeutic class — specific (HIC3) Ace Inhibitor-Thiazide Or Thiazide-Like Diuretic
AHFS code 24:32.04.00
AHFS class Angiotensin-Converting Enzyme Inhibitors
FDB label name QUINAPRIL-HCTZ 10-12.5 MG TAB
FDB brand name Quinapril-Hydrochlorothiazide
Legend status F — Federal legend — prescription drug or device
GPI-1436991802650320
GPI classQuinapril-hydroCHLOROthiazide
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other cardiovascular shortages

Quinapril/Hydrochlorothiazide Tablet shortage FAQs

Is Quinapril/Hydrochlorothiazide Tablet in shortage?
Yes — the FDA currently lists Quinapril/Hydrochlorothiazide Tablet in shortage (status: “Current”, first reported Jan 19, 2023). 6 of 6 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Why is Quinapril/Hydrochlorothiazide Tablet in shortage?
The manufacturer-reported reason on file with the FDA: Discontinuation of the manufacture of the drug.
Which products are affected?
Quinapril Hydrochloride And Hydrochlorothiazide, Tablet, 12.5 mg; 10 mg (NDC 65862-161-90) (NDC 65862-0161-90); Quinapril Hydrochloride And Hydrochlorothiazide, Tablet, 25 mg; 20 mg (NDC 65862-163-90) (NDC 65862-0163-90); Quinapril Hydrochloride And Hydrochlorothiazide, Tablet, 12.5 mg; 20 mg (NDC 65862-162-90) (NDC 65862-0162-90). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Quinapril/Hydrochlorothiazide Tablet be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Quinapril/Hydrochlorothiazide somewhere?
Other manufacturers (Lupin Pharmaceuticals,Inc., Aurobindo Pharma Limited, Cipla USA Inc.) still market it and have not reported a shortage. See “Where else can I get Quinapril/Hydrochlorothiazide Tablet?” above — stock still varies by pharmacy.
What should I do if I take Quinapril/Hydrochlorothiazide Tablet?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Quinapril/Hydrochlorothiazide Tablet shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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