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Hydrochlorothiazide Capsule shortage

Hydrochlorothiazide Capsule is currently listed in shortage by the FDA. The FDA lists 2 affected products. This page was last refreshed from FDA data on Oct 4, 2026.

To Be Discontinued ⚠ Supply risk: High Cardiovascular 2 products 319 days First posted Nov 19, 2025 Updated Nov 19, 2025
Here’s the bottom line

Teva is permanently stopping its hydrochlorothiazide 12.5 mg capsules. Other makers, including Actavis Pharma and Unichem Pharmaceuticals, still list this same strength and form as available.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
2
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/1
Affected strengths supplied
319
Days in shortage
4,367
Medicaid Rx (2025)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 4, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Hydrochlorothiazide Capsule. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
2 NDCs
To be discontinued 2
Affected strengths still supplied
Among manufacturers reporting this shortage
0/1 strengths
No supply 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Hydrochlorothiazide Capsule from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Actavis Pharma, Inc. Unichem Pharmaceuticals (USA), Inc. Quality Care Products LLC A-S Medication Solutions ScieGen Pharmaceuticals Inc AvPAK Rising Pharma Holdings, Inc. American Health Packaging Proficient Rx LP Bryant Ranch Prepack Aurobindo Pharma Limited Aphena Pharma Solutions - Tennessee, LLC
Plus 7 alternative dosage forms of Hydrochlorothiazide.
See all other options & details →
Shortage timeline
  1. Nov 19, 2025
    Currently in shortage
    2 of 2 products affected.
  2. Nov 19, 2025
    First reported to the FDA
    2 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Teva Pharmaceuticals USA, Inc. 📞 800-545-8800 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Microzide, Capsule, 12.5 mg (NDC 0591-0347-01) NDC 00591-0347-01 — — A business decision was made to discontinue manufacture of the drug. —
To Be Discontinued Microzide, Capsule, 12.5 mg (NDC 0591-0347-05) NDC 00591-0347-05 — — A business decision was made to discontinue manufacture of the drug. —

These rows are manufacturer reports to the FDA for Hydrochlorothiazide Capsule — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Hydrochlorothiazide Capsule? options further down this page.

Why is Hydrochlorothiazide Capsule in shortage?

Teva Pharmaceuticals has made a business decision to permanently stop making their brand-name version of hydrochlorothiazide capsules, called Microzide, in the 12.5 mg strength. This affects two specific package sizes of that product. They haven't shared a more detailed public reason beyond it being a business decision on their part.

It's worth knowing that this report only covers Teva's Microzide capsules specifically — it doesn't mean hydrochlorothiazide as a whole is going away. Other manufacturers may still be producing their own versions of this medication, and those would be listed separately.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Hydrochlorothiazide Capsule, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Hydrochlorothiazide Capsule?

Hydrochlorothiazide 12.5 mg capsules are currently on the FDA shortage list. The maker that filed this report, Teva Pharmaceuticals, has listed its 12.5 mg capsule (sold as Microzide) as to be discontinued, which means this particular product may not come back.

The one strength covered here — 12.5 mg — has no available source from Teva right now. The reason given is a business decision to stop making the drug, not a safety problem. Because this is a discontinuation rather than a temporary delay, there is no estimated recovery date for Teva's product. Importantly, this report reflects only Teva; other companies still make the same 12.5 mg capsule.

Please do not stop or change how you take this medicine on your own — talk with your pharmacist or prescriber first. Here are good next steps:

  • Ask your pharmacy to check wholesalers and other manufacturers for the same 12.5 mg capsule. Several companies — including Actavis, Unichem, ScieGen, Rising, Aurobindo, and others — still make hydrochlorothiazide 12.5 mg capsules, though a given one may not be in local stock.
  • If your exact product cannot be found, ask your prescriber or pharmacist about a suitable option.

Manufacturer contact numbers are listed on this page for reference; pharmacies usually make these calls. This national data may not match your local pharmacy's actual stock.

See “Where else can I get Hydrochlorothiazide Capsule?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Hydrochlorothiazide guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Hydrochlorothiazide guide →

Where else can I get Hydrochlorothiazide Capsule?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Hydrochlorothiazide Capsule is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule, Gelatin Coated · Oral Actavis Pharma, Inc. 00591-0347-00
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral Unichem Pharmaceuticals (USA), Inc. 29300-0130-01
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral Quality Care Products LLC 35356-0807-30
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral A-S Medication Solutions 50090-0724-00
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral ScieGen Pharmaceuticals Inc 50228-0146-01
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral AvPAK 50268-0404-15
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral Rising Pharma Holdings, Inc. 57237-0002-01
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral American Health Packaging 60687-0683-01
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule, Gelatin Coated · Oral Proficient Rx LP 63187-0548-07
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral Bryant Ranch Prepack 63629-8498-01
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule · Oral Aurobindo Pharma Limited 65862-0113-01
Hydrochlorothiazide HYDROCHLOROTHIAZIDE 12.5 mg/1 Capsule, Gelatin Coated · Oral Aphena Pharma Solutions - Tennessee, LLC 67544-0739-60

Alternative dosage forms of Hydrochlorothiazide

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 30 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Hydrochlorothiazide 12.5 mgNDC 00591-0347-01 Actavis 100 capsules $0.028 AB Availability likely
hydrochlorothiazide 12.5 mgNDC 29300-0130-01 Unichem 100 capsules $0.028 AB Availability likely
Hydrochlorothiazide 12.5 mgNDC 50228-0146-01 ScieGen 100 capsules $0.028 AB Availability likely
Hydrochlorothiazide 12.5 mgNDC 50268-0404-15 AvPAK 50 capsules $0.028 AB Availability likely
Hydrochlorothiazide 12.5 mgNDC 57237-0002-01 Rising 100 capsules $0.028 AB Availability likely
hydrochlorothiazide 12.5 mgNDC 60687-0683-01 American 100 capsules $0.028 AB Availability likely
Hydrochlorothiazide 12.5 mgNDC 69367-0219-01 Westminster 100 capsules $0.028 AB Availability likely
Hydrochlorothiazide 12.5 mgNDC 00591-0347-05 Actavis 500 capsules $0.028 AB Availability likely
Hydrochlorothiazide 12.5 mgNDC 00615-8344-05 NCS 15 capsules — AB FDA listed
hydrochlorothiazide 12.5 mgNDC 35356-0807-30 Quality 30 capsules — AB Discontinued
Hydrochlorothiazide 12.5 mgNDC 42708-0027-30 QPharma, 30 capsules — AB FDA listed
hydrochlorothiazide 12.5 mgNDC 42708-0086-30 QPharma 30 capsules — AB FDA listed
hydrochlorothiazide 12.5 mgNDC 46708-0438-10 Alembic 100 capsules — — FDA listed
hydrochlorothiazide 12.5 mgNDC 50090-0724-00 A-S 30 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 50090-6987-00 A-S 30 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 50090-6988-00 A-S 90 capsules — AB FDA listed
hydrochlorothiazide 12.5 mgNDC 51655-0522-26 Northwind 90 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 51655-0616-26 Northwind 90 capsules — AB FDA listed
hydrochlorothiazide 12.5 mgNDC 62332-0070-10 Alembic 100 capsules — — FDA listed
Hydrochlorothiazide 12.5 mgNDC 63187-0548-07 Proficient 7 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 63629-8498-01 Bryant 500 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 65862-0113-01 Aurobindo 100 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 67544-0739-60 Aphena 90 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 68788-7683-01 Preferred 100 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 68788-8862-01 Preferred 100 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 70518-2550-00 REMEDYREPACK 30 capsules — AB FDA listed
hydrochlorothiazide 12.5 mgNDC 71205-0161-07 Proficient 7 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 71205-0589-30 Proficient 30 capsules — AB FDA listed
Hydrochlorothiazide 12.5 mgNDC 71205-0980-00 Proficient 100 capsules — AB FDA listed
hydrochlorothiazide 12.5 mgNDC 71335-0067-01 Bryant 30 capsules — AB FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Hydrochlorothiazide Capsule — that fall in the same broad treatment class (thiazide and related diuretics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 029832
GCN 34820
HICL code 003649
Ingredient (HICL) Hydrochlorothiazide
HIC1 code R
Therapeutic class — broad (HIC1) Kidney/Urinary Tract
HIC2 code R1
Therapeutic class — intermediate (HIC2) Affect Primarily Kidneys/Urinary Tract
HIC3 code R1F
Therapeutic class — specific (HIC3) Thiazide And Related Diuretics
AHFS code 24:36.20.00
AHFS class Thiazide Diuretics (24:36)
FDB label name HYDROCHLOROTHIAZIDE 12.5 MG CP
FDB brand name Hydrochlorothiazide
Legend status F — Federal legend — prescription drug or device
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other cardiovascular shortages

Hydrochlorothiazide Capsule shortage FAQs

Is Hydrochlorothiazide Capsule in shortage?
Yes — the FDA currently lists Hydrochlorothiazide Capsule in shortage (status: “To Be Discontinued”, first reported Nov 19, 2025). 2 of 2 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Microzide, Capsule, 12.5 mg (NDC 0591-0347-01) (NDC 00591-0347-01); Microzide, Capsule, 12.5 mg (NDC 0591-0347-05) (NDC 00591-0347-05). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Hydrochlorothiazide Capsule be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Hydrochlorothiazide somewhere?
Other manufacturers (Actavis Pharma, Inc., Unichem Pharmaceuticals (USA), Inc., Quality Care Products LLC and others) still market it and have not reported a shortage. 7 alternative dosage forms of Hydrochlorothiazide are also listed. See “Where else can I get Hydrochlorothiazide Capsule?” above — stock still varies by pharmacy.
What should I do if I take Hydrochlorothiazide Capsule?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Hydrochlorothiazide Capsule shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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