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Vigabatrin Oral Solution shortage

Vigabatrin Oral Solution is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Sep 23, 2026.

To Be Discontinued ⚠ Supply risk: High Neurology 1 product 342 days First posted Oct 16, 2025 Updated Oct 16, 2025
Here’s the bottom line

Pyros Pharmaceuticals is stopping production of vigabatrin oral solution, and this change may be permanent. Other makers have not reported a shortage and still list vigabatrin oral solution (powder for solution) at the same strength.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
1
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/1
Affected strengths supplied
342
Days in shortage
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Sep 23, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Vigabatrin Oral Solution. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
1 NDCs
To be discontinued 1
Affected strengths still supplied
Among manufacturers reporting this shortage
0/1 strengths
No supply 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Vigabatrin Oral Solution from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Upsher-Smith Laboratories, LLC Actavis Pharma, Inc. Camber Pharmaceuticals, Inc. Dr. Reddys Laboratories Inc., Par Health USA, LLC Aurobindo Pharma Limited Lundbeck Pharmaceuticals LLC Ascend Laboratories, LLC Cipla USA, Inc.
Plus 11 alternative dosage forms of Vigabatrin.
See all other options & details →
Shortage timeline
  1. Oct 16, 2025
    Currently in shortage
    1 of 1 product affected.
  2. Oct 16, 2025
    First reported to the FDA
    1 product first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Pyros Pharmaceuticals, Inc. 📞 763-315-2000 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Vigpoder, Oral Solution, 50 mg/1 mL (NDC 80789-117-50) NDC 80789-0117-50 Discontinuation of the manufacture of the drug

These rows are manufacturer reports to the FDA for Vigabatrin Oral Solution — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Vigabatrin Oral Solution? options further down this page.

Why is Vigabatrin Oral Solution in shortage?

Pyros Pharmaceuticals has let the FDA know that they are permanently stopping the manufacturing of their vigabatrin oral solution, Vigpoder, in the 50 mg/1 mL strength. No specific reason was shared publicly for why they made this decision — just that they are discontinuing production of this particular product.

It's worth knowing that this report only covers Pyros Pharmaceuticals and their version of this medication. It doesn't mean vigabatrin oral solution is disappearing from every manufacturer out there — this is specific to Vigpoder (50 mg/1 mL) from Pyros.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Vigabatrin Oral Solution, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Vigabatrin Oral Solution?

Vigabatrin oral solution is currently on the FDA shortage list, and I want to walk you through what this means for you.

The only strength on this record, 50 mg/1 mL, does not have an available source right now. The reason reported is that the manufacturer, Pyros Pharmaceuticals, is discontinuing production of its product (Vigpoder). Because this is listed as a discontinuation, this particular supply problem may be permanent — so a conversation with your prescriber is the right next step rather than something to handle alone.

The good thing to know is that this report reflects only one manufacturer. Several other companies make the same medicine, vigabatrin, in the same 50 mg/mL strength — for example products from Upsher-Smith, Actavis, Camber, Dr. Reddy's, Lundbeck (Sabril), and others. Your pharmacy may be able to source one of these, though it may not be in local stock today.

Here is what I'd suggest, in order:

  1. Do not stop, skip, or change your dose on your own.
  2. Ask your pharmacy to check wholesalers and other manufacturers for the same medicine.
  3. Talk with your prescriber or pharmacist about which option fits you, since this product is being discontinued.

Manufacturer contact numbers are listed on this page for reference; pharmacies usually make these calls.

See “Where else can I get Vigabatrin Oral Solution?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Vigabatrin guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Vigabatrin guide →

Where else can I get Vigabatrin Oral Solution?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Vigabatrin Oral Solution is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Vigadrone VIGABATRIN 50 mg/mL Powder, For Solution · Oral Upsher-Smith Laboratories, LLC 00245-0556-50
Vigabatrin VIGABATRIN 50 mg/mL Powder, For Solution Actavis Pharma, Inc. 00591-3955-50
Vigabatrin For Oral Solution VIGABATRIN 50 mg/mL Powder, For Solution · Oral Camber Pharmaceuticals, Inc. 31722-0009-50
Vigabatrin VIGABATRIN 50 mg/mL Powder, For Solution · Oral Dr. Reddys Laboratories Inc., 43598-0697-50
Vigabatrin VIGABATRIN 50 mg/mL Powder, For Solution · Oral Par Health USA, LLC 49884-0358-03
Vigabatrin VIGABATRIN 500 mg/1 Powder, For Solution · Oral Aurobindo Pharma Limited 59651-0366-50
Sabril VIGABATRIN 50 mg/mL Powder, For Solution · Oral Lundbeck Pharmaceuticals LLC 67386-0211-65
Vigabatrin VIGABATRIN 50 mg/mL Powder, For Solution · Oral Ascend Laboratories, LLC 67877-0674-63
Vigabatrin VIGABATRIN 500 mg/mL Powder, For Solution · Oral Cipla USA, Inc. 69097-0964-53

Alternative dosage forms of Vigabatrin

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 1 productclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Vigpoder 50 mg/mLNDC 80789-0117-50 Pyros 50 packets AA Discontinued

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Vigabatrin Oral Solution — that fall in the same broad treatment class (anticonvulsants) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 017869
GCN 64314
HICL code 007377
Ingredient (HICL) Vigabatrin
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H4
Therapeutic class — intermediate (HIC2) Anticonvulsants
HIC3 code H4B
Therapeutic class — specific (HIC3) Anticonvulsants
AHFS code 28:12.28.00
AHFS class Gaba-Mediated Anticonvulsants
FDB label name VIGPODER 500 MG POWDER PACKET
FDB brand name Vigpoder
Legend status F — Federal legend — prescription drug or device
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other neurology shortages

Vigabatrin Oral Solution shortage FAQs

Is Vigabatrin Oral Solution in shortage?
Yes — the FDA currently lists Vigabatrin Oral Solution in shortage (status: “To Be Discontinued”, first reported Oct 16, 2025). 1 of 1 product is affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Vigpoder, Oral Solution, 50 mg/1 mL (NDC 80789-117-50) (NDC 80789-0117-50). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Vigabatrin Oral Solution be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Vigabatrin somewhere?
Other manufacturers (Upsher-Smith Laboratories, LLC, Actavis Pharma, Inc., Camber Pharmaceuticals, Inc. and others) still market it and have not reported a shortage. 11 alternative dosage forms of Vigabatrin are also listed. See “Where else can I get Vigabatrin Oral Solution?” above — stock still varies by pharmacy.
What should I do if I take Vigabatrin Oral Solution?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Vigabatrin Oral Solution shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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