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Lamotrigine Tablet, Extended Release shortage

Lamotrigine Tablet, Extended Release is currently listed in shortage by the FDA. The FDA lists 6 affected products. This page was last refreshed from FDA data on Sep 23, 2026.

To Be Discontinued ⚠ Supply risk: High Neurology 6 products 147 days First posted Apr 29, 2026 Updated Apr 29, 2026
Here’s the bottom line

Par Pharma is permanently stopping its lamotrigine extended-release tablets. Other makers not reporting a shortage still list lamotrigine in orally disintegrating tablet form, but the extended-release tablet specifically has no available source reported right now.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
6
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/6
Affected strengths supplied
147
Days in shortage
5,108
Medicaid Rx (2026)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Sep 23, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Lamotrigine Tablet, Extended Release. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
6 NDCs
To be discontinued 6
Affected strengths still supplied
Among manufacturers reporting this shortage
0/6 strengths
No supply 6
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Lamotrigine Tablet, Extended Release from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Amneal Pharmaceuticals of New York LLC GlaxoSmithKline LLC
Plus 5 alternative dosage forms of Lamotrigine Tablet, Extended Release.
See all other options & details →
Shortage timeline
  1. Apr 29, 2026
    Currently in shortage
    6 of 6 products affected.
  2. Apr 29, 2026
    First reported to the FDA
    6 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Par Health, Inc. 📞 800-828-9393 6 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Lamotrigine, Tablet, Extended Release, 25 mg (NDC 49884-561-11) NDC 49884-0561-11 Discontinuation of the manufacture of the drug
To Be Discontinued Lamotrigine, Tablet, Extended Release, 250 mg (NDC 49884-604-11) NDC 49884-0604-11 Discontinuation of the manufacture of the drug
To Be Discontinued Lamotrigine, Tablet, Extended Release, 200 mg (NDC 49884-564-11) NDC 49884-0564-11 Discontinuation of the manufacture of the drug
To Be Discontinued Lamotrigine, Tablet, Extended Release, 50 mg (NDC 49884-562-11) NDC 49884-0562-11 Discontinuation of the manufacture of the drug
To Be Discontinued Lamotrigine, Tablet, Extended Release, 100 mg (NDC 49884-563-11) NDC 49884-0563-11 Discontinuation of the manufacture of the drug
To Be Discontinued Lamotrigine, Tablet, Extended Release, 300 mg (NDC 49884-605-11) NDC 49884-0605-11 Discontinuation of the manufacture of the drug

These rows are manufacturer reports to the FDA for Lamotrigine Tablet, Extended Release — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Lamotrigine Tablet, Extended Release? options further down this page.

Why is Lamotrigine Tablet, Extended Release in shortage?

Par Pharmaceutical is permanently stopping production of their extended-release lamotrigine tablets — and this affects every strength they made: 25 mg, 50 mg, 100 mg, 200 mg, 250 mg, and 300 mg. They haven't shared a specific public reason for why they made this decision, just that manufacturing of these products is being discontinued for good.

It's worth knowing that this report only covers Par Pharmaceutical's versions of this medication. Other companies that make extended-release lamotrigine are not part of this particular report, and their status would be listed separately.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Lamotrigine Tablet, Extended Release, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Lamotrigine Tablet, Extended Release?

Lamotrigine extended-release tablets are currently on the FDA shortage list. The one manufacturer on this record, Par Health, Inc., has reported that it is discontinuing this product, so I want to walk you through what that means and your next steps.

This affects every strength on the record — the 25 mg, 50 mg, 100 mg, 200 mg, 250 mg, and 300 mg extended-release tablets. All of these show no available source right now, and the reason listed is that the manufacturer is stopping production. Because this is a discontinuation rather than a temporary delay, the supply problem from this maker may be permanent, and a conversation with your prescriber is the right next step.

Please do not let this worry you into acting on your own. Here is how I would approach it:

  • Do not stop, skip, or change your dose on your own — stopping suddenly can be harmful.
  • Ask your pharmacy to check wholesalers and other manufacturers for extended-release lamotrigine.
  • The same medicine, lamotrigine, is still made by other companies in different forms (for example Amneal and GlaxoSmithKline products); your pharmacy may be able to source one, though it may not be in local stock.
  • Ask your prescriber or pharmacist which option best matches your current dose.

Manufacturer contact numbers are listed on this page for reference, though pharmacies usually make these calls. This is national, manufacturer-reported information and may not match your local pharmacy's stock.

See “Where else can I get Lamotrigine Tablet, Extended Release?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Lamotrigine guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Lamotrigine guide →

Where else can I get Lamotrigine Tablet, Extended Release?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Lamotrigine Tablet, Extended Release is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Lamotrigine LAMOTRIGINE 25 mg/1 Tablet, Orally Disintegrating · Oral Amneal Pharmaceuticals of New York LLC 00115-1526-08
Lamotrigine LAMOTRIGINE 50 mg/1 Tablet, Orally Disintegrating · Oral Amneal Pharmaceuticals of New York LLC 00115-1527-08
Lamotrigine LAMOTRIGINE 100 mg/1 Tablet, Orally Disintegrating · Oral Amneal Pharmaceuticals of New York LLC 00115-1528-08
Lamotrigine LAMOTRIGINE 200 mg/1 Tablet, Orally Disintegrating · Oral Amneal Pharmaceuticals of New York LLC 00115-1529-08
Lamictal LAMOTRIGINE 5 mg/1 Tablet, For Suspension · Oral GlaxoSmithKline LLC 00173-0526-00
Lamictal LAMOTRIGINE 25 mg/1 Tablet, For Suspension · Oral GlaxoSmithKline LLC 00173-0527-00
Lamictal LAMOTRIGINE 25 mg/1 Tablet · Oral GlaxoSmithKline LLC 00173-0633-02
Lamictal LAMOTRIGINE 100 mg/1 Tablet · Oral GlaxoSmithKline LLC 00173-0642-55
Lamictal LAMOTRIGINE 150 mg/1 Tablet · Oral GlaxoSmithKline LLC 00173-0643-60
Lamictal LAMOTRIGINE 200 mg/1 Tablet · Oral GlaxoSmithKline LLC 00173-0644-60
Lamictal LAMOTRIGINE 2 mg/1 Tablet, For Suspension · Oral GlaxoSmithKline LLC 00173-0699-00
Lamictal Xr LAMOTRIGINE 25 mg/1 Tablet, Film Coated, Extended Release · Oral GlaxoSmithKline LLC 00173-0754-00

Alternative dosage forms of Lamotrigine Tablet, Extended Release

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 30 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Lamotrigine 25 mgNDC 00228-1410-03 Actavis 30 tablets $0.254 AB Discontinued
Lamotrigine 25 mgNDC 16714-0623-01 NorthStar 30 tablets $0.254 AB Availability likely
lamotrigine 25 mgNDC 31722-0240-30 Camber 30 tablets $0.254 AB Availability likely
Lamotrigine Extended Release 25 mgNDC 49884-0561-11 Par 30 tablets $0.254 Availability likely
Lamotrigine 25 mgNDC 65162-0949-03 Amneal 30 tablets $0.254 AB Availability likely
Lamotrigine 200 mgNDC 00228-1453-03 Actavis 30 tablets $0.618 save 20% AB Availability likely
Lamotrigine 200 mgNDC 16714-0626-01 NorthStar 30 tablets $0.618 save 20% AB Availability likely
lamotrigine 200 mgNDC 31722-0243-30 Camber 30 tablets $0.618 save 20% AB Availability likely
Lamotrigine 200 mgNDC 65162-0986-03 Amneal 30 tablets $0.618 save 20% AB Availability likely
Lamotrigine Extended Release 200 mgNDC 49884-0564-11 Par 30 tablets $0.775 Discontinued
Lamotrigine 250 mgNDC 00228-1638-03 Actavis 30 tablets $1.253 AB Availability likely
Lamotrigine 250 mgNDC 16714-0893-01 NorthStar 30 tablets $1.253 AB Availability likely
lamotrigine 250 mgNDC 31722-0244-30 Camber 30 tablets $1.253 AB Availability likely
Lamotrigine Extended Release 250 mgNDC 49884-0604-11 Par 30 tablets $1.253 Availability likely
Lamotrigine 250 mgNDC 65162-0988-03 Amneal 30 tablets $1.253 AB Availability likely
Lamictal Xr 25 mgNDC 00173-0754-00 GlaxoSmithKline 30 tablets $14.204 +5492% AB Availability likely
Lamictal Xr 200 mgNDC 00173-0757-00 GlaxoSmithKline 30 tablets $32.331 +4074% AB Availability likely
Lamictal Xr 250 mgNDC 00173-0781-00 GlaxoSmithKline 30 tablets $44.163 +3424% AB Availability likely
Lamotrigine 25 mgNDC 13668-0339-01 Torrent 100 tablets AB FDA listed
Lamotrigine 25 mgNDC 42291-0443-30 AvKARE 30 tablets AB FDA listed
Lamotrigine 25 mgNDC 55111-0717-05 Dr.Reddy's 500 tablets AB FDA listed
Lamotrigine 25 mgNDC 68382-0979-05 Zydus 500 tablets AB FDA listed
lamotrigine 25 mgNDC 69117-0044-01 Yiling 30 tablets AB FDA listed
Lamotrigine 25 mgNDC 70771-1514-03 Zydus 30 tablets AB FDA listed
Lamotrigine 25 mgNDC 71335-1469-01 Bryant 30 tablets AB FDA listed
Lamotrigine Extended-Release 250 mgNDC 10370-0334-11 Par 30 tablets AB FDA listed
Lamotrigine 250 mgNDC 42291-0447-30 AvKARE 30 tablets AB FDA listed
Lamotrigine 250 mgNDC 46708-0418-30 Alembic 30 tablets AB FDA listed
Lamotrigine 250 mgNDC 55111-0419-05 Dr.Reddy's 500 tablets AB FDA listed
Lamotrigine 250 mgNDC 62332-0418-30 Alembic 30 tablets AB FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Lamotrigine Tablet, Extended Release — that fall in the same broad treatment class (anticonvulsants) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 065250
GCN 24693
HICL code 007378
Ingredient (HICL) Lamotrigine
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H4
Therapeutic class — intermediate (HIC2) Anticonvulsants
HIC3 code H4B
Therapeutic class — specific (HIC3) Anticonvulsants
AHFS code 28:12.92.00
AHFS class Anticonvulsants, Miscellaneous
FDB label name LAMOTRIGINE ER 25 MG TABLET
FDB brand name Lamotrigine Er
Legend status F — Federal legend — prescription drug or device
GPI-1472600040007510
GPI classlamoTRIgine ER
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other neurology shortages

Lamotrigine Tablet, Extended Release shortage FAQs

Is Lamotrigine Tablet, Extended Release in shortage?
Yes — the FDA currently lists Lamotrigine Tablet, Extended Release in shortage (status: “To Be Discontinued”, first reported Apr 29, 2026). 6 of 6 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Lamotrigine, Tablet, Extended Release, 25 mg (NDC 49884-561-11) (NDC 49884-0561-11); Lamotrigine, Tablet, Extended Release, 250 mg (NDC 49884-604-11) (NDC 49884-0604-11); Lamotrigine, Tablet, Extended Release, 200 mg (NDC 49884-564-11) (NDC 49884-0564-11). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Lamotrigine Tablet, Extended Release be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Lamotrigine Tablet, Extended Release somewhere?
Other manufacturers (Amneal Pharmaceuticals of New York LLC, GlaxoSmithKline LLC) still market it and have not reported a shortage. 5 alternative dosage forms of Lamotrigine Tablet, Extended Release are also listed. See “Where else can I get Lamotrigine Tablet, Extended Release?” above — stock still varies by pharmacy.
What should I do if I take Lamotrigine Tablet, Extended Release?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Lamotrigine Tablet, Extended Release shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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