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Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution shortage

Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Oct 2, 2026.

To Be Discontinued ⚠ Supply risk: High Renal 1 product 23 days First posted Sep 10, 2026 Updated Sep 10, 2026
Here’s the bottom line

Fresenius Medical Care is permanently stopping production of this IV solution (dextrose monohydrate, sodium chloride, sodium lactate, calcium chloride, and magnesium chloride). No other manufacturers are currently listed as a source for any strength of this product.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available.

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
1
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/1
Affected strengths supplied
23
Days in shortage
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 2, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
1 NDCs
To be discontinued 1
Affected strengths still supplied
Among manufacturers reporting this shortage
0/1 strengths
No supply 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
Other manufacturers
We couldn’t automatically confirm other manufacturers of Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution that aren’t reporting a shortage. Ask your pharmacist whether a different manufacturer or strength can be ordered.
Shortage timeline
  1. Sep 10, 2026
    Currently in shortage
    1 of 1 product affected.
  2. Sep 10, 2026
    First reported to the FDA
    1 product first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Fresenius Medical Care North America 📞 800-323-5188 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued DELFLEX, Solution, 18.4 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 46163-212-95) NDC 46163-0212-95 — — A business decision was made to discontinue manufacture of the drug. —

These rows are manufacturer reports to the FDA for Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution? options further down this page.

Why is Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution in shortage?

Fresenius Medical Care North America has made a business decision to permanently stop making this specific DELFLEX solution — the 4.25 g/100 mL strength combination product (NDC 46163-212-95). No specific public reason beyond it being a business decision was shared with the FDA.

It's worth knowing that this report only covers what Fresenius Medical Care North America filed with the FDA about their product. It doesn't speak to what other manufacturers may or may not have available.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution?

The combination solution you take — dextrose monohydrate, sodium chloride, sodium lactate, calcium chloride, and magnesium chloride (DELFLEX) — is currently on the FDA drug-shortage list. I want to walk you through what this means so you can plan your next steps calmly.

This shortage covers all reported strengths of this product: 18.4 mg/100 mL, 4.25 g/100 mL, 5.08 mg/100 mL, 538 mg/100 mL, and 448 mg/100 mL. None of these currently has an available source. The reason reported is a business decision by the manufacturer to discontinue making the drug, which means this supply problem may be permanent rather than temporary.

Because this product is being discontinued, a conversation with your prescriber is the most important next step. Please do not stop or change how you use this solution on your own.

  • Do not skip or adjust your treatment without professional guidance.
  • Ask your pharmacy to check wholesalers and other suppliers for any remaining stock.
  • Talk with your prescriber or pharmacist soon about a clinician-chosen alternative, since this product is being discontinued.
  • A manufacturer contact number is listed on this page for reference; pharmacies usually handle these calls.

This is general, national information and may not match your local pharmacy's stock.

If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Therapeutic equivalents & pricing 2 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Delflex 4.25 g/100mL; 538 mg/100mL; 448 mg/100mL; 18.4 mg/100mL; 5.08 mg/100mLNDC 46163-0212-95 Fresenius 2000 ml — AT FDA listed
Delflex 4.25 g/100mL; 538 mg/100mL; 448 mg/100mL; 18.4 mg/100mL; 5.08 mg/100mLNDC 49230-0212-23 Fresenius 2000 ml — AT FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other renal shortages

Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution shortage FAQs

Is Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution in shortage?
Yes — the FDA currently lists Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution in shortage (status: “To Be Discontinued”, first reported Sep 10, 2026). 1 of 1 product is affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
DELFLEX, Solution, 18.4 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 46163-212-95) (NDC 46163-0212-95). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
What should I do if I take Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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