Peritoneal Dialysis Solution shortage
Peritoneal Dialysis Solution is currently listed in shortage by the FDA. The FDA lists 6 affected products. This page was last refreshed from FDA data on Oct 1, 2026.
Fresenius Medical Care is discontinuing its current peritoneal dialysis solution products, replacing them with new labeling under a different NDC code. Delflex peritoneal dialysis solutions are still listed as available from other Fresenius entities and may be an option.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Peritoneal Dialysis Solution. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Mar 10, 2026Currently in shortage6 of 6 products affected.
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Mar 10, 2026First reported to the FDA6 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Fresenius Medical Care North America 📞 800-323-5188 6 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | DELFLEX® w/Dextrose, Solution, 4.25% Low Mg/Low Ca 2.5L/3L, 5/cs (NDC 46163-212-94) | — | — | The NDC codes are being discontinued, to be replaced with NDC labeler code #46163. | — |
| To Be Discontinued | DELFLEX® w/Dextrose, Solution, 2.5% Low Mg/Low Ca 2.5L/3L, 5/cs (NDC 49230-209-94) | — | — | The NDC codes are being discontinued, to be replaced with NDC labeler code #46163. | — |
| To Be Discontinued | DELFLEX® w/Dextrose, Solution, 4.25% Low Mg/Low Ca 2L, 5/cs (NDC 46163-212-92) | — | — | The NDC codes are being discontinued, to be replaced with NDC labeler code #46163. | — |
| To Be Discontinued | DELFLEX® w/Dextrose, Solution, 2.5% Low Mg/Low Ca 2L, 5/cs (NDC 49230-209-92) | — | — | The NDC codes are being discontinued, to be replaced with NDC labeler code #46163. | — |
| To Be Discontinued | DELFLEX® w/Dextrose, Solution, 1.5% Low Mg/Low Ca 2.5L/3L, 5/cs (NDC 49230-206-94) | — | — | The NDC codes are being discontinued, to be replaced with NDC labeler code #46163. | — |
| To Be Discontinued | DELFLEX® w/Dextrose, Solution, 1.5% Low Mg/Low Ca 2L, 5/cs (NDC 46163-206-92) | — | — | The NDC codes are being discontinued, to be replaced with NDC labeler code #46163. | — |
These rows are manufacturer reports to the FDA for Peritoneal Dialysis Solution — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Peritoneal Dialysis Solution? options further down this page.
Why is Peritoneal Dialysis Solution in shortage?
Here's what's going on with this one. Fresenius Medical Care North America has reported that the specific product codes (called NDC codes) for several of their DELFLEX® Peritoneal Dialysis Solutions are being discontinued. This affects the 1.5%, 2.5%, and 4.25% Low Mg/Low Ca strengths in both the 2L and 2.5L/3L bag sizes (sold in cases of 5).
The good news is that this appears to be a labeling and coding change rather than the product going away entirely. According to Fresenius, these old NDC codes are being replaced with a new NDC labeler code (#46163). No specific reason was given for why this change is happening, and no timeline was shared beyond the fact that the switch is underway.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Peritoneal Dialysis Solution, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Peritoneal Dialysis Solution?
Peritoneal Dialysis Solution (the DELFLEX with Dextrose line) is currently on the FDA shortage list, and the manufacturer has listed these products as to be discontinued. Because dialysis solution is central to your treatment, this deserves prompt attention — but it is manageable with a plan.
All six reported strengths are affected, and none currently show an available source from this manufacturer: 1.5%, 2.5%, and 4.25% Low Mg/Low Ca, in both the 2L and 2.5L/3L sizes. The reason given is that the current NDC codes are being discontinued and replaced under a new NDC labeler code (#46163). Since these products are marked as discontinued, this supply change may be lasting, which makes a conversation with your care team the right next step.
Please do not change how you use your solution on your own. Here is a practical order of steps:
- Do not stop, skip, or adjust your prescribed dialysis solution without talking to your prescriber or pharmacist first.
- Ask your dialysis provider or pharmacy to check whether the replacement (new NDC) or the same Delflex solution from another Fresenius supplier is available; it may not be in local stock.
- Because these items are being discontinued, ask your prescriber which solution to move to next.
Manufacturer contact numbers are listed on this page for reference; your provider usually makes these calls.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Where else can I get Peritoneal Dialysis Solution?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Peritoneal Dialysis Solution is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Delflex | DEXTROSE MONOHYDRATE 1.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Solution · Intraperitoneal | Fresenius Medical Care de Mexico, S.A. de C.V. | 46163-0206-94 |
| Delflex | SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 448 mg/100mL; CALCIUM CHLORIDE 18.4 | Solution · Intraperitoneal | Fresenius Medical Care de Mexico, S.A. de C.V. | 46163-0209-92 |
| Delflex | DEXTROSE MONOHYDRATE 1.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Solution · Intraperitoneal | Fresenius Medical Care Renal Therapies Group, LLC | 49230-0206-20 |
| Delflex | DEXTROSE MONOHYDRATE 2.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Solution · Intraperitoneal | Fresenius Medical Care Renal Therapies Group, LLC | 49230-0209-23 |
Alternative dosage forms of Peritoneal Dialysis
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 4 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Delflex 4.25 g/100mL; 538 mg/100mL; 448 mg/100mL; 18.4 mg/100mL; 5.08 mg/100mL | Fresenius | 2500 ml | — | AT | FDA listed |
| Delflex 4.25 g/100mL; 538 mg/100mL; 448 mg/100mL; 18.4 mg/100mL; 5.08 mg/100mL | Fresenius | 2000 ml | — | AT | FDA listed |
| Delflex 2.5 g/100mL; 538 mg/100mL; 448 mg/100mL; 18.4 mg/100mL; 5.08 mg/100mL | Fresenius | 2500 ml | — | AT | FDA listed |
| Delflex 4.25 g/100mL; 538 mg/100mL; 448 mg/100mL; 18.4 mg/100mL; 5.08 mg/100mL | Fresenius | 2000 ml | — | AT | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Peritoneal Dialysis Solution — that fall in the same broad treatment class (dialysis solutions) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Other renal shortages
Peritoneal Dialysis Solution shortage FAQs
Is Peritoneal Dialysis Solution in shortage?
Which products are affected?
When will Peritoneal Dialysis Solution be available again?
Can I still get Peritoneal Dialysis somewhere?
What should I do if I take Peritoneal Dialysis Solution?
Still have a question about the Peritoneal Dialysis Solution shortage?
Ask a pharmacist about this shortage →View Peritoneal Dialysis Solution on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.