Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution shortage
Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution is currently listed in shortage by the FDA. The FDA lists 18 affected products. This page was last refreshed from FDA data on Oct 2, 2026.
Vantive US Healthcare LLC is stopping production of this peritoneal dialysis solution, and the change may be permanent. Related Dianeal products from Vantive are still listed as available, which may serve as alternatives.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Aug 3, 2026Currently in shortage18 of 18 products affected.
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Aug 3, 2026First reported to the FDA18 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Vantive US Healthcare LLC 📞 800-284-4060 18 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 1.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0426-53) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0429-52) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 1.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0411-07) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 1.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0426-52) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 2.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0427-52) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL Low Calcium with Dextrose, Intraperitoneal Injection, Solution, 18.3 mg/100 mL; 1.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0409-07) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL Low Calcium with Dextrose, Intraperitoneal Injection, Solution, 18.3 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0459-05) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL Low Calcium with Dextrose, Intraperitoneal Injection, Solution, 18.3 mg/100 mL; 2.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0457-05) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 2.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0427-53) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 2.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0413-07) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 1.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0411-06) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL Low Calcium with Dextrose, Intraperitoneal Injection, Solution, 18.3 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0433-51) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0415-07) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0429-53) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0415-06) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL Low Calcium with Dextrose, Intraperitoneal Injection, Solution, 18.3 mg/100 mL; 2.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0430-51) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL Low Calcium with Dextrose, Intraperitoneal Injection, Solution, 18.3 mg/100 mL; 1.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0424-51) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
| To Be Discontinued | DIANEAL PD-2 with Dextrose, Intraperitoneal Injection, Solution, 25.7 mg/100 mL; 2.5 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 0941-0413-06) | — | — | A business decision was made to discontinue manufacture of the drug. | — |
These rows are manufacturer reports to the FDA for Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution? options further down this page.
Why is Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution in shortage?
Vantive US Healthcare LLC has made a business decision to permanently stop making all of the DIANEAL peritoneal dialysis solutions they reported to the FDA. This affects every strength and formulation in their lineup — including DIANEAL PD-2 with Dextrose (in the 1.5%, 2.5%, and 4.25% dextrose concentrations) and DIANEAL Low Calcium with Dextrose (also in the 1.5%, 2.5%, and 4.25% dextrose concentrations).
No specific reason beyond "a business decision" was shared publicly by the manufacturer — they didn't give a more detailed explanation. No dates were provided about when remaining supplies might run out. It's also worth knowing that this report covers only Vantive US Healthcare LLC's products, so it reflects their decision alone and not the availability of peritoneal dialysis solutions from any other manufacturers.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution?
Your peritoneal dialysis solution — the DIANEAL PD-2 and DIANEAL Low Calcium with Dextrose products (containing calcium chloride, dextrose, magnesium chloride, sodium chloride, and sodium lactate) — is currently on the FDA shortage list. I want to walk you through what this means so you can plan with your care team.
All of the listed strengths are reported with no available source right now, including the dextrose concentrations of 1.5 g/100 mL, 2.5 g/100 mL, and 4.25 g/100 mL. The reason given is a business decision to discontinue making these products. Because this is a discontinuation rather than a temporary delay, this supply problem may be permanent, and a conversation with your prescriber is the right next step.
Please keep this in mind:
- Do not stop, skip, or change your dialysis solution on your own.
- Ask your pharmacy or dialysis provider to check wholesalers for remaining stock.
- The same DIANEAL solutions are still listed from Vantive US Healthcare LLC; your pharmacy may be able to source one of these, though it may not be in local stock.
- Ask your prescriber about a clinician-chosen alternative that fits your dialysis needs.
A manufacturer contact number is listed on this page for reference, though pharmacies usually handle these calls. This is general, national information and may not match your local supply.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 1.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0409-01 |
| Dianeal Pd-2 With Dextrose | DEXTROSE MONOHYDRATE 1.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0411-04 |
| Dianeal Pd-2 With Dextrose | DEXTROSE MONOHYDRATE 2.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0413-01 |
| Dianeal Pd-2 With Dextrose | DEXTROSE MONOHYDRATE 4.25 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0415-01 |
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 2.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0430-52 |
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 4.25 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0433-52 |
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 1.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0686-08 |
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 1.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0727-02 |
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 2.5 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE 4 | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0729-02 |
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 4.25 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0731-02 |
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 1.36 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0733-04 |
| Dianeal Low Calcium With Dextrose | DEXTROSE MONOHYDRATE 2.27 g/100mL; SODIUM CHLORIDE 538 mg/100mL; SODIUM LACTATE | Injection, Solution · Intraperitoneal | Vantive US Healthcare LLC | 00941-0735-04 |
Alternative dosage forms of Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection,
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 6 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| DIANEAL PD-2 with Dextrose 1.5 g/100mL; 538 mg/100mL; 448 mg/100mL; 25.7 mg/100mL; 5.08 mg/100mL | Vantive | 3000 ml | — | AT | FDA listed |
| DIANEAL PD-2 with Dextrose 1.5 g/100mL; 538 mg/100mL; 448 mg/100mL; 25.7 mg/100mL; 5.08 mg/100mL | Vantive | 2500 ml | — | AT | FDA listed |
| DIANEAL PD-2 with Dextrose 4.25 g/100mL; 538 mg/100mL; 448 mg/100mL; 25.7 mg/100mL; 5.08 mg/100mL | Vantive | 6000 ml | — | AT | FDA listed |
| DIANEAL PD-2 with Dextrose 4.25 g/100mL; 538 mg/100mL; 448 mg/100mL; 25.7 mg/100mL; 5.08 mg/100mL | Vantive | 2000 ml | — | AT | FDA listed |
| DIANEAL PD-2 with Dextrose 1.5 g/100mL; 538 mg/100mL; 448 mg/100mL; 25.7 mg/100mL; 5.08 mg/100mL | Vantive | 5000 ml | — | AT | FDA listed |
| DIANEAL PD-2 with Dextrose 1.5 g/100mL; 538 mg/100mL; 448 mg/100mL; 25.7 mg/100mL; 5.08 mg/100mL | Vantive | 2000 ml | — | AT | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution — that fall in the same broad treatment class (dialysis solutions) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other renal shortages
Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution shortage FAQs
Is Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution in shortage?
Which products are affected?
When will Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution be available again?
Can I still get Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, somewhere?
What should I do if I take Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution?
Still have a question about the Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution shortage?
Ask a pharmacist about this shortage →View Calcium Chloride; Dextrose; Magnesium Ch... on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.