Sodium Chloride 0.9% Injection shortage
Sodium Chloride 0.9% Injection is currently listed in shortage by the FDA. The FDA lists 3 affected products. This page was last refreshed from FDA data on Sep 16, 2026.
Pfizer (Hospira) is permanently stopping its Sodium Chloride 0.9% Injection in 50 mL, 100 mL, and 250 mL ADD-Vantage® flexible containers. Other makers — including B. Braun, Baxter, Nephron, and ICU Medical — still list sodium chloride 0.9% injection as available.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Sodium Chloride 0.9% Injection. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Dec 3, 2025Currently in shortage3 of 3 products affected.
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Dec 3, 2025First reported to the FDA3 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Hospira, Inc., a Pfizer Company 📞 844-646-4398 3 NDCS click to expand
| Status | NDC / product | Size | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | Sodium Chloride 0.9%, Injection, 100 mL ADD-Vantage® Flexible Container (NDC 0409-7101-67) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Sodium Chloride 0.9%, Injection, 250 mL ADD-Vantage® Flexible Container (NDC 0409-7101-02) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Sodium Chloride 0.9%, Injection, 50 mL ADD-Vantage® Flexible Container (NDC 0409-7101-66) | — | — | Discontinuation of the manufacture of the drug | — |
These rows are manufacturer reports to the FDA for Sodium Chloride 0.9% Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Sodium Chloride 0.9% Injection? options further down this page.
Why is Sodium Chloride 0.9% Injection in shortage?
Hospira, Inc. (a Pfizer company) has permanently stopped making three specific versions of Sodium Chloride 0.9% Injection — the 50 mL, 100 mL, and 250 mL ADD-Vantage® Flexible Containers. This isn't a temporary supply hiccup or factory delay; the company has made a decision to discontinue manufacturing these particular products for good.
It's worth knowing that this report only covers Hospira's ADD-Vantage® versions of this saline solution. The manufacturer did not share a specific public reason for why they made this decision — just that production of these three package sizes is permanently ending.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Sodium Chloride 0.9% Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Sodium Chloride 0.9% Injection?
Sodium Chloride 0.9% Injection is currently on the FDA drug-shortage list. The specific product affected here is the ADD-Vantage® Flexible Container line, which is listed as being discontinued by its manufacturer.
At this time, none of the three ADD-Vantage® sizes have an available source from the manufacturer that filed this report: the 50 mL, 100 mL, and 250 mL containers are all affected. The reason given is that this maker (Hospira, a Pfizer company) is stopping production of these particular containers. Because this is a discontinuation rather than a temporary delay, the supply problem for these specific products may be permanent. It's worth knowing this report covers only one manufacturer's version — the same medicine is still made by other companies in other container types.
What you can do:
- Do not stop, skip, or change how you use this product on your own. Talk with your pharmacist or prescriber first.
- Ask your pharmacy about the same medicine from another maker — Sodium Chloride 0.9% Injection is also listed from B. Braun, Baxter, Nephron, ICU Medical, Becton Dickinson, Fresenius, and HealthFirst. It may not be in local stock, but your pharmacy can check wholesalers.
- Since the ADD-Vantage® containers are being discontinued, ask your prescriber or pharmacist about a suitable replacement.
Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle these calls. This is general, national information and may not match your local pharmacy's stock.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Sodium Chloride 0.9% Injection?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Sodium Chloride 0.9% Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Sodium Chloride | SODIUM CHLORIDE 9 mg/mL | Injection, Solution · Intravenous | B. Braun Medical Inc. | 00264-1800-31 |
| Sodium Chloride | SODIUM CHLORIDE .9 g/100mL | Injection, Solution · Intravenous | B. Braun Medical Inc. | 00264-5802-00 |
| Sodium Chloride | SODIUM CHLORIDE 9 mg/mL | Injection · Intravenous | B. Braun Medical Inc. | 00264-9375-88 |
| Sodium Chloride | SODIUM CHLORIDE 9 g/1000mL | Injection, Solution · Intravenous | Baxter Healthcare Corporation | 00338-0049-01 |
| Sodium Chloride | SODIUM CHLORIDE 900 mg/100mL | Injection · Intravenous | Baxter Healthcare Corporation | 00338-0553-11 |
| Sodium Chloride | SODIUM CHLORIDE 450 mg/50mL | Injection · Intravenous | Baxter Healthcare Corporation | 00338-9151-30 |
| Sodium Chloride | SODIUM CHLORIDE 9 mg/mL | Injection · Intravenous | Nephron Pharmaceuticals Corporation | 00487-4301-05 |
| Sodium Chloride | SODIUM CHLORIDE 900 mg/100mL | Injection, Solution · Intravenous | ICU Medical Inc. | 00990-7983-02 |
| Sodium Chloride | SODIUM CHLORIDE 9 mg/mL | Injection, Solution · Intravenous | Becton Dickinson and Company | 17271-0701-02 |
| Sodium Chloride | SODIUM CHLORIDE 900 mg/100mL | Injection · Intravenous | Fresenius Medical Care de Mexico, S.A. de C.V. | 46163-0300-10 |
| Sodium Chloride | SODIUM CHLORIDE 900 mg/100mL | Injection · Intravenous | Fresenius Medical Care Renal Therapies Group, LLC | 49230-0300-10 |
| 0.9% Sodium Chloride | SODIUM CHLORIDE 9 g/1000mL | Injection, Solution · Intravenous | HF Acquisition Co LLC, DBA HealthFirst | 51662-1609-01 |
Therapeutic equivalents & pricing 15 productsclick to expand
Orange Book–rated equivalents of the affected sizes, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Sodium Chloride 900 mg/100mL | Hospira, | 24 pouches | $0.021 | AP | Availability likely |
| Sodium Chloride 900 mg/100mL | HF | 500 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Baxter | 100 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Baxter | 100 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | ICU | 48 pouches | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Baxter | 100 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Baxter | 100 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Baxter | 100 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Baxter | 100 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Baxter | 50 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Fresenius | 1000 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Hospira, | 10 pouches | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Fresenius | 1000 ml | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | ICU | 24 pouches | — | AP | FDA listed |
| Sodium Chloride 900 mg/100mL | Hospira, | 10 pouches | — | AP | Discontinued |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Sodium Chloride 0.9% Injection — that fall in the same broad treatment class (sodium/saline preparations) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Sodium Chloride 0.9% Injection shortage FAQs
Is Sodium Chloride 0.9% Injection in shortage?
Which products are affected?
When will Sodium Chloride 0.9% Injection be available again?
Can I still get Sodium Chloride 0.9% somewhere?
What should I do if I take Sodium Chloride 0.9% Injection?
Still have a question about the Sodium Chloride 0.9% Injection shortage?
Ask a pharmacist about this shortage →View Sodium Chloride 0.9% Injection on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.