Sodium Acetate Injection shortage
Sodium Acetate Injection is currently listed in shortage by the FDA. The FDA lists 15 affected products. The reported reason: Other. This page was last refreshed from FDA data on Sep 23, 2026.
Sodium Acetate Injection has been on the FDA shortage list for over a year, though all five reporting manufacturers still show some supply available. Every strength currently has at least one source, and additional supply is also listed from Amneal Pharmaceuticals.
Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers (see options) and your prescriber about a long-term plan.
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Sodium Acetate Injection. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
-
Sep 18, 2026Currently in shortage15 of 15 products affected.
-
Sep 16, 2026FDA refreshed this shortage record4 products updated.
-
Sep 15, 2026FDA refreshed this shortage record1 product updated.
-
Sep 11, 2026FDA refreshed this shortage record2 products updated.
-
Sep 9, 2026FDA refreshed this shortage record5 products updated.
-
Aug 24, 2026FDA refreshed this shortage record1 product updated.
-
Mar 23, 2016More presentations reported3 more products added to the shortage.
-
Feb 3, 2016First reported to the FDA12 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Fresenius Kabi USA, LLC 📞 888-386-1300 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Sodium Acetate, Injection, 4 meq/100 mL (NDC 63323-032-00) | — | Available | Check wholesalers for inventory | — |
Manufacturer: Hikma Pharmaceuticals USA, Inc. 📞 800-631-2174 2 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Sodium Acetate, Injection, 100 mEq/50mL (2 mEq/mL) (NDC 0641-6262-01) | — | Available | Additional lots will be available. Product will be made available as it is released. | — |
| Current | Sodium Acetate, Injection, 40 mEq/20mL (2 mEq/mL) (NDC 0641-6261-01) | — | Available | Additional lots will be available. Product will be made available as it is released. | — |
Manufacturer: Hospira, Inc., a Pfizer Company 📞 844-646-4398 6 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Sodium Acetate, Injection, 200 mEq/100 mL (2 mEq/mL) (NDC 0409-3299-25) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 100 mEq/50 mL (2 mEq/mL) (NDC 0409-3299-05) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 100 mEq/50 mL (2 mEq/mL) (NDC 0409-3299-26) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 40 mEq/20 mL (2 mEq/mL) (NDC 0409-7299-25) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 40 mEq/20 mL (2 mEq/mL) (NDC 0409-7299-73) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 200 mEq/100 mL (2 mEq/mL) (NDC 0409-3299-06) | — | Limited Availability | Next Delivery and Estimated Recovery: September 2026. Shortage per Manufacturer: Manufacturing Delay | Other |
Manufacturer: Milla Pharmaceuticals 📞 833-251-8463 4 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Sodium Acetate, Injection, 200 mEq/100mL (2 mEq/mL) (NDC 71357-008-10) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 40 mEq/20mL (2 mEq/mL) (NDC 71357-002-10) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 100 mEq/50mL (2 mEq/mL) (NDC 71357-007-10) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 400 mEq/100mL (4 mEq/mL) (NDC 71357-009-10) | — | Limited Availability | Estimated recovery: TBD | Other |
Manufacturer: Somerset Therapeutics, LLC 📞 732-554-1037 2 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Sodium Acetate, Injection, 164 mg/1 mL (NDC 70069-048-20) | — | Available | — | — |
| Current | Sodium Acetate, Injection, 164 mg/1 mL (NDC 70069-047-25) | — | Available | — | — |
These rows are manufacturer reports to the FDA for Sodium Acetate Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Sodium Acetate Injection? options further down this page.
Why is Sodium Acetate Injection in shortage?
There are two specific products in this shortage report that have limited availability. Hospira (a Pfizer company) is reporting a manufacturing delay — basically a hold-up at the factory — affecting their 200 mEq/100 mL (2 mEq/mL) sodium acetate injection. They expect their next delivery and recovery from that shortage around September 2026. Separately, Milla Pharmaceuticals has limited availability of their 400 mEq/100 mL (4 mEq/mL) product, and they haven't given a specific reason beyond "other" — with no estimated recovery date yet (listed as TBD).
It's worth knowing that several other strengths and package sizes from these same manufacturers — as well as products from Hikma, Somerset Therapeutics, Fresenius Kabi, and Hospira's other package sizes — are currently listed as available. So the shortage is really centered on those two specific products, not sodium acetate injection as a whole from every maker.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Sodium Acetate Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Sodium Acetate Injection?
Sodium Acetate Injection is currently on the FDA drug-shortage list, but supply overall remains steady. This product is given through an IV in a clinical setting, so any adjustments are handled by your care team rather than by you at home.
Every strength on this record still has an available source. That includes the 40 mEq/20 mL, 100 mEq/50 mL, 200 mEq/100 mL, and 400 mEq/100 mL (all 2 or 4 mEq/mL versions), as well as the 164 mg/mL and 4 mEq/100 mL products. No strength is completely without a source right now. A few items are tighter than others — the 400 mEq/100 mL is listed as limited with recovery still to be determined, and one 200 mEq/100 mL lot has an estimated recovery of September 2026 — but other makers still supply these sizes.
The FDA lists the reason simply as "Other," and all five manufacturers on this record are still reporting available supply. That is a reassuring sign.
Here is what I suggest:
- Do not skip or change any dose on your own; your care team manages this medicine.
- Ask your pharmacy to order your strength — they can check wholesalers and other manufacturers.
- The same medicine is also made by Amneal (164 mg/mL); your pharmacy may be able to source it, though it may not be in local stock.
Manufacturer contact numbers are listed on this page for reference, though pharmacies usually handle those calls.
This is general, national information and may not match your local pharmacy's stock.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Sodium Acetate Injection?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Sodium Acetate Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Sodium Acetate | SODIUM ACETATE ANHYDROUS 164 mg/mL | Injection, Solution, Concentrate · Intravenous | Amneal Pharmaceuticals Private Limited | 80830-2436-02 |
Alternative dosage forms of Sodium Acetate
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 15 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Sodium Acetate 4 meq/100mL | Fresenius | 20 vials | — | AP | FDA listed |
| Sodium Acetate 400 meq/100mL | MILLA | 10 vials | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | Hospira, | 25 vials | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | Hikma | 1 vial | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | Hikma | 10 vials | — | AP | FDA listed |
| Sodium acetate anhydrous 164 mg/mL | Somerset | 25 vials | — | AP | FDA listed |
| Sodium acetate anhydrous 164 mg/mL | Somerset | 20 vials | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | MILLA | 10 vials | — | AP | FDA listed |
| Sodium Acetate 200 meq/100mL | MILLA | 10 vials | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | Amneal | 25 vials | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | Amneal | 10 vials | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | Hikma | 1 vial | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | Amneal | 25 bottles | — | AP | FDA listed |
| Sodium Acetate 3.28 g/20mL | Hospira, | 25 vials | — | AP | FDA listed |
| Sodium Acetate 164 mg/mL | MILLA | 10 vials | — | AP | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Sodium Acetate Injection — that fall in the same broad treatment class (bicarbonate producing/containing agents) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Sodium Acetate Injection shortage FAQs
Is Sodium Acetate Injection in shortage?
Why is Sodium Acetate Injection in shortage?
Which products are affected?
When will Sodium Acetate Injection be available again?
Can I still get Sodium Acetate somewhere?
What should I do if I take Sodium Acetate Injection?
Still have a question about the Sodium Acetate Injection shortage?
Ask a pharmacist about this shortage →View Sodium Acetate Injection on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.