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Azithromycin Tablet shortage

Azithromycin Tablet is currently listed in shortage by the FDA. The FDA lists 2 affected products. This page was last refreshed from FDA data on Sep 22, 2026.

To Be Discontinued ⚠ Supply risk: High Anti-Infective 2 products 166 days First posted Apr 9, 2026 Updated Apr 9, 2026
Here’s the bottom line

Pfizer is permanently stopping production of its azithromycin tablets in both the 250 mg and 500 mg strengths. Other makers — including those that sell Zithromax (azithromycin) tablets — still list supply of both strengths.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
2
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/2
Affected strengths supplied
166
Days in shortage
123
Medicaid Rx (2025)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Sep 22, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Azithromycin Tablet. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
2 NDCs
To be discontinued 2
Affected strengths still supplied
Among manufacturers reporting this shortage
0/2 strengths
No supply 2
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Azithromycin Tablet from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Pfizer Laboratories Div Pfizer Inc Lannett Company, Inc. Sandoz Inc Major Pharmaceuticals AvKARE
Plus 15 alternative dosage forms of Azithromycin.
See all other options & details →
Shortage timeline
  1. Apr 9, 2026
    Currently in shortage
    2 of 2 products affected.
  2. Apr 9, 2026
    First reported to the FDA
    2 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Pfizer Inc. 📞 800-533-4535 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Zithromax, Tablet, 500 mg (NDC 0069-3070-30) NDC 00069-3070-30 Discontinuation of the manufacture of the drug
To Be Discontinued Zithromax, Tablet, 250 mg (NDC 0069-4061-01) NDC 00069-4061-01 Discontinuation of the manufacture of the drug

These rows are manufacturer reports to the FDA for Azithromycin Tablet — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Azithromycin Tablet? options further down this page.

Why is Azithromycin Tablet in shortage?

Pfizer has let the FDA know that they are permanently stopping the manufacturing of their brand-name Zithromax azithromycin tablets — specifically the 250 mg and 500 mg tablet versions. This applies to Pfizer's own product and is not a temporary hold-up at the factory; it's a permanent decision to stop making these particular tablets altogether.

It's worth knowing that Pfizer did not share a specific public reason for why they made this decision — just that manufacturing is being discontinued. This report only reflects Pfizer's branded Zithromax tablets, so it doesn't speak to what other manufacturers may or may not have available.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Azithromycin Tablet, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Azithromycin Tablet?

Azithromycin tablets are currently listed on the FDA drug-shortage list. I know that can feel unsettling, so let me walk you through what this report actually shows.

The record filed here comes from Pfizer, the maker of the brand Zithromax, and it covers both the 250 mg and 500 mg tablets. Neither strength has an available source from this manufacturer right now. The reason listed is that Pfizer is discontinuing manufacture of these tablets, so for this maker the supply problem may be permanent rather than short-term. No estimated recovery date is given because the product is being discontinued.

It is important to know that this report reflects only Pfizer's filing. Azithromycin is the same medicine whether it comes from one company or another, and other makers still hold records for the same tablets — including Lannett, Sandoz, Major Pharmaceuticals, and AvKARE.

Here is what I suggest:

  • Do not stop, skip, or change your dose on your own.
  • Ask your pharmacy to order azithromycin from another manufacturer, such as those listed above; your pharmacy can check wholesalers, though a given brand may not be in local stock.
  • If your exact tablet cannot be found, ask your prescriber or pharmacist about a clinician-chosen option.

Manufacturer contact numbers appear on this page for reference; pharmacies usually handle those calls.

This is general, national information and may not match your pharmacy's actual stock.

See “Where else can I get Azithromycin Tablet?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Azithromycin guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Azithromycin guide →

Where else can I get Azithromycin Tablet?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Azithromycin Tablet is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Zithromax AZITHROMYCIN DIHYDRATE 250 mg/1 Tablet, Film Coated · Oral Pfizer Laboratories Div Pfizer Inc 00069-3060-30
Zithromax AZITHROMYCIN DIHYDRATE 500 mg/1 Tablet, Film Coated · Oral Pfizer Laboratories Div Pfizer Inc 00069-3070-75
Azithromycin AZITHROMYCIN DIHYDRATE 250 mg/1 Tablet, Film Coated · Oral Lannett Company, Inc. 00527-2370-20
Azithromycin AZITHROMYCIN DIHYDRATE 500 mg/1 Tablet, Film Coated · Oral Lannett Company, Inc. 00527-2395-19
Azithromycin AZITHROMYCIN DIHYDRATE 250 mg/1 Tablet, Film Coated · Oral Sandoz Inc 00781-8089-26
Azithromycin AZITHROMYCIN DIHYDRATE 500 mg/1 Tablet, Film Coated · Oral Sandoz Inc 00781-8090-03
Azithromycin AZITHROMYCIN DIHYDRATE 600 mg/1 Tablet, Film Coated · Oral Sandoz Inc 00781-8091-31
Azithromycin AZITHROMYCIN DIHYDRATE 250 mg/1 Tablet, Film Coated · Oral Major Pharmaceuticals 00904-7350-06
Azithromycin AZITHROMYCIN DIHYDRATE 500 mg/1 Tablet, Film Coated · Oral Major Pharmaceuticals 00904-7351-04
Azithromycin AZITHROMYCIN MONOHYDRATE 600 mg/1 Tablet, Film Coated · Oral AvKARE 42291-0044-30
Azithromycin AZITHROMYCIN DIHYDRATE 250 mg/1 Tablet, Film Coated · Oral AvKARE 42291-0082-06
Azithromycin AZITHROMYCIN DIHYDRATE 500 mg/1 Tablet, Film Coated · Oral AvKARE 42291-0083-03

Alternative dosage forms of Azithromycin

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 30 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
azithromycin 250 mgNDC 00527-2370-32 Lannett 30 tablets $0.268 save 87% AB Availability likely
Azithromycin 250 mgNDC 00781-8089-26 Sandoz 1 tablet $0.268 save 87% AB Availability likely
azithromycin 250 mgNDC 00904-7350-06 Major 50 tablets $0.268 save 87% AB Availability likely
Azithromycin 250 mgNDC 50111-0787-10 Teva 30 tablets $0.268 save 87% AB Availability likely
Azithromycin 250 mgNDC 60687-0742-01 American 100 tablets $0.268 save 87% AB Availability likely
Azithromycin Dihydrate 250 mgNDC 68094-0900-06 Precision 6 tablets $0.268 save 87% AB Availability likely
azithromycin 250 mgNDC 68180-0861-06 Lupin 30 tablets $0.268 save 87% AB Availability likely
Azithromycin 250 mgNDC 69452-0171-04 Bionpharma 6 tablets $0.268 save 87% AB Availability likely
Azithromycin Dihydrate 250 mgNDC 50268-0074-13 AvPAK 1 tablet $0.357 save 83% AB Discontinued
Azithromycin Dihydrate 250 mgNDC 51224-0022-06 TAGI 6 tablets $0.357 save 83% AB FDA listed
azithromycin 500 mgNDC 00527-2395-32 Lannett 30 tablets $0.560 AB Availability likely
Azithromycin 500 mgNDC 00781-8090-03 Sandoz 3 tablets $0.560 AB Availability likely
azithromycin 500 mgNDC 00904-7351-04 Major 30 tablets $0.560 AB Availability likely
Azithromycin 500 mgNDC 50111-0788-10 Teva 30 tablets $0.560 AB Availability likely
Azithromycin 500 mgNDC 60687-0753-21 American 30 tablets $0.560 AB Availability likely
Azithromycin 500 mgNDC 65862-0642-30 Aurobindo 30 tablets $0.560 AB Availability likely
Azithromycin Dihydrate 500 mgNDC 68094-0799-03 Precision 3 tablets $0.560 AB Availability likely
azithromycin 500 mgNDC 68180-0862-06 Lupin 30 tablets $0.560 AB Availability likely
Azithromycin 500 mgNDC 69452-0172-13 Bionpharma 30 tablets $0.560 AB Availability likely
Azithromycin Dihydrate 500 mgNDC 51224-0122-03 TAGI 3 tablets $0.676 AB Discontinued
Zithromax 250 mgNDC 00069-4061-01 Pfizer 30 tablets $2.067 AB Availability likely
Zithromax 250 mgNDC 00069-3060-30 Pfizer 30 tablets $2.081 +1% AB Discontinued
Zithromax 500 mgNDC 00069-3070-30 Pfizer 30 tablets AB FDA listed
Azithromycin 500 mgNDC 42291-0083-03 AvKARE 3 tablets AB FDA listed
Azithromycin 500 mgNDC 46708-0058-03 Alembic 3 tablets AB FDA listed
Azithromycin 500 mgNDC 50090-5366-00 A-S 5 tablets AB FDA listed
Azithromycin 500 mgNDC 50090-5376-00 A-S 2 tablets AB FDA listed
Azithromycin Dihydrate 500 mgNDC 50090-7298-00 A-S 5 tablets AB FDA listed
Azithromycin Dihydrate 500 mgNDC 50090-7299-00 A-S 2 tablets AB FDA listed
Azithromycin Dihydrate 500 mgNDC 50090-7506-00 A-S 1 tablet AB FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Azithromycin Tablet — that fall in the same broad treatment class (macrolide antibiotics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 022624
GCN 61198
HICL code 006334
Ingredient (HICL) Azithromycin
HIC1 code W
Therapeutic class — broad (HIC1) Anti-Infecting Agents
HIC2 code W1
Therapeutic class — intermediate (HIC2) Antibiotics
HIC3 code W1D
Therapeutic class — specific (HIC3) Macrolide Antibiotics
AHFS code 08:12.12.08
AHFS class Other Macrolide Antibiotics
FDB label name ZITHROMAX 500 MG TABLET
FDB brand name Zithromax
Legend status F — Federal legend — prescription drug or device
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other anti-infective shortages

Azithromycin Tablet shortage FAQs

Is Azithromycin Tablet in shortage?
Yes — the FDA currently lists Azithromycin Tablet in shortage (status: “To Be Discontinued”, first reported Apr 9, 2026). 2 of 2 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Zithromax, Tablet, 500 mg (NDC 0069-3070-30) (NDC 00069-3070-30); Zithromax, Tablet, 250 mg (NDC 0069-4061-01) (NDC 00069-4061-01). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Azithromycin Tablet be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Azithromycin somewhere?
Other manufacturers (Pfizer Laboratories Div Pfizer Inc, Lannett Company, Inc., Sandoz Inc and others) still market it and have not reported a shortage. 15 alternative dosage forms of Azithromycin are also listed. See “Where else can I get Azithromycin Tablet?” above — stock still varies by pharmacy.
What should I do if I take Azithromycin Tablet?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Azithromycin Tablet shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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