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Calcium Chloride Injection shortage

Calcium Chloride Injection is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Sep 25, 2026.

To Be Discontinued ⚠ Supply risk: High Cardiovascular, Endocrinology/Metabolism 1 product 322 days First posted Nov 7, 2025 Updated Nov 7, 2025
Here’s the bottom line

Hospira (a Pfizer company) is stopping production of Calcium Chloride Injection 100 mg/mL, and this change may be permanent. No other manufacturers are currently listed as a source for this medicine.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
1
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/1
Affected strengths supplied
322
Days in shortage
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Sep 25, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Calcium Chloride Injection. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
1 NDCs
To be discontinued 1
Affected strengths still supplied
Among manufacturers reporting this shortage
0/1 strengths
No supply 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Calcium Chloride Injection from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Plus 1 alternative dosage form of Calcium Chloride.
See all other options & details →
Shortage timeline
  1. Nov 7, 2025
    Currently in shortage
    1 of 1 product affected.
  2. Nov 7, 2025
    First reported to the FDA
    1 product first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Hospira, Inc., a Pfizer Company 📞 844-646-4398 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Calcium Chloride, Injection, 100 mg/1 mL (NDC 0409-4928-34) NDC 00409-4928-34 — — Discontinuation of the manufacture of the drug —

These rows are manufacturer reports to the FDA for Calcium Chloride Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Calcium Chloride Injection? options further down this page.

Why is Calcium Chloride Injection in shortage?

Hospira, Inc. (a Pfizer company) has let the FDA know that they are permanently stopping the manufacture of their Calcium Chloride Injection 100 mg/1 mL product (the specific package listed under NDC 0409-4928-34). This means that particular product from Hospira will no longer be made going forward.

It's worth knowing that Hospira did not share a specific public reason why they made this decision — just that manufacturing of this product is being discontinued. This report reflects only what Hospira has filed with the FDA, so it applies only to their specific 100 mg/1 mL presentation, not necessarily to every version of calcium chloride injection that exists on the market.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Calcium Chloride Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Calcium Chloride Injection?

Calcium Chloride Injection (100 mg/1 mL) is currently on the FDA drug-shortage list, and the record shows this product is being discontinued by the manufacturer that filed the report.

The single strength tracked here, 100 mg/1 mL, has no available source reported at this time. There is no other strength listed with active supply, and our records do not show another maker for this same medicine on this report.

The reason given is straightforward: the manufacturer, Hospira, Inc. (a Pfizer Company), has reported discontinuing production of this drug. Because this is a discontinuation rather than a temporary delay, the supply problem may be permanent. That makes a conversation with your prescriber the right next step, since they can plan ahead for your care.

Here is what I suggest, in order:

  1. Do not stop, skip, or change how you use this medicine on your own.
  2. Ask your pharmacy to check wholesalers and other manufacturers — local stock can differ from national reports.
  3. Because this strength is being discontinued, talk with your prescriber or pharmacist about a clinician-chosen option that fits your needs.

A manufacturer contact number is listed on this page for reference, though pharmacies usually handle those calls. This is general information and may not match your pharmacy's actual stock.

See “Where else can I get Calcium Chloride Injection?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Calcium Chloride guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Calcium Chloride guide →

Where else can I get Calcium Chloride Injection?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Calcium Chloride Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Alternative dosage forms of Calcium Chloride

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 13 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Calcium Chloride 100 mg/mLNDC 00409-1631-10 Hospira, 1 syringe — AP FDA listed
Calcium Chloride 100 mg/mLNDC 51662-1209-01 HF 1 syringe — — FDA listed
Calcium Chloride 100 mg/mLNDC 51662-1379-01 HF 1 syringe — AP FDA listed
Calcium Chloride 100 mg/mLNDC 51662-1452-01 HF 1 syringe — AP FDA listed
Calcium Chloride 100 mg/mLNDC 64253-0900-36 Medefil, 60 syringes — AP FDA listed
calcium chloride 100 mg/mLNDC 70121-2308-04 Amneal 1 syringe — AP FDA listed
Calcium Chloride 100 mg/mLNDC 70518-4180-00 REMEDYREPACK 10 syringes — AP FDA listed
Calcium Chloride 100 mg/mLNDC 71872-7044-01 Medical 1 syringe — — FDA listed
Calcium Chloride 100 mg/mLNDC 71872-7045-01 Medical 1 syringe — AP FDA listed
Calcium Chloride 100 mg/mLNDC 71872-7193-01 Medical 1 syringe — AP FDA listed
Calcium Chloride 100 mg/mLNDC 76329-3304-01 International 10 syringes — AP FDA listed
Calcium Chloride 100 mg/mLNDC 84549-0304-01 ProPharma 10 ml — AP FDA listed
Calcium Chloride 100 mg/mLNDC 00409-4928-34 Hospira, 1 syringe — — Discontinued

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Calcium Chloride Injection — that fall in the same broad treatment class (calcium replacement) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 001349
GCN 03751
HICL code 000582
Ingredient (HICL) Calcium Chloride
HIC1 code C
Therapeutic class — broad (HIC1) Electrolyte Balance/Metabolism/Nutrition
HIC2 code C1
Therapeutic class — intermediate (HIC2) Drugs Affecting Electrolyte Balance
HIC3 code C1F
Therapeutic class — specific (HIC3) Calcium Replacement
AHFS code 40:12.00.00
AHFS class Replacement Preparations
FDB label name CALCIUM CHLORIDE 1 GM/10ML SYR
FDB brand name Calcium Chloride
Legend status F — Federal legend — prescription drug or device
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other cardiovascular, endocrinology/metabolism shortages

Calcium Chloride Injection shortage FAQs

Is Calcium Chloride Injection in shortage?
Yes — the FDA currently lists Calcium Chloride Injection in shortage (status: “To Be Discontinued”, first reported Nov 7, 2025). 1 of 1 product is affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Calcium Chloride, Injection, 100 mg/1 mL (NDC 0409-4928-34) (NDC 00409-4928-34). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Calcium Chloride Injection be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Calcium Chloride somewhere?
1 alternative dosage form of Calcium Chloride is also listed. See “Where else can I get Calcium Chloride Injection?” above — stock still varies by pharmacy.
What should I do if I take Calcium Chloride Injection?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Calcium Chloride Injection shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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