Home › NDC Lookup › Drug shortages › Ampicillin Sodium Injection

Ampicillin Sodium Injection shortage

Ampicillin Sodium Injection is currently listed in shortage by the FDA. The FDA lists 5 affected products. This page was last refreshed from FDA data on Oct 3, 2026.

To Be Discontinued ⚠ Supply risk: High Anti-Infective 5 products 299 days First posted Dec 8, 2025 Updated Dec 8, 2025
Here’s the bottom line

Sandoz is stopping its private-label ampicillin sodium injection, and this change may be permanent. Other makers — including Sagent Pharmaceuticals and WG Critical Care — still list ampicillin sodium injection in multiple strengths, including 125 mg, 250 mg, 500 mg, and 1 g.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
5
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/3
Affected strengths supplied
299
Days in shortage
147
Medicaid Rx (2026)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 3, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Ampicillin Sodium Injection. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
5 NDCs
To be discontinued 5
Affected strengths still supplied
Among manufacturers reporting this shortage
0/3 strengths
No supply 3
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Ampicillin Sodium Injection from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Sandoz Inc Sagent Pharmaceuticals WG Critical Care, LLC
Plus 3 alternative dosage forms of Ampicillin Sodium.
See all other options & details →
Shortage timeline
  1. Dec 8, 2025
    Currently in shortage
    5 of 5 products affected.
  2. Dec 8, 2025
    First reported to the FDA
    5 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Sandoz Inc. 📞 800-525-8747 5 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Ampicillin Sodium, Injection, 2 g (NDC 0781-9413-92) NDC 00781-9413-92 — — Discontinuation of private label only —
To Be Discontinued Ampicillin Sodium, Injection, 2 g (NDC 0781-9408-95) NDC 00781-9408-95 — — Discontinuation of private label only —
To Be Discontinued Ampicillin Sodium, Injection, 1 g (NDC 0781-9404-95) NDC 00781-9404-95 — — Discontinuation of private label only —
To Be Discontinued Ampicillin Sodium, Injection, 10 g (NDC 0781-9409-95) NDC 00781-9409-95 — — Discontinuation of private label only —
To Be Discontinued Ampicillin Sodium, Injection, 1 g (NDC 0781-9412-92) NDC 00781-9412-92 — — Discontinuation of private label only —

These rows are manufacturer reports to the FDA for Ampicillin Sodium Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Ampicillin Sodium Injection? options further down this page.

Why is Ampicillin Sodium Injection in shortage?

Here's what's going on with this one. Sandoz is permanently stopping certain specific versions of ampicillin sodium injection — the 1 g, 2 g, and 10 g strengths — but only what's called their "private label" products. A private label product is essentially the same medicine sold under a different brand or distributor name, rather than directly under Sandoz's own label.

It's worth knowing that Sandoz did not share a more detailed public reason for why they're making this change. Also, because this only affects their private label versions, it does not necessarily mean all ampicillin sodium injection products from this manufacturer are going away — and other manufacturers may make this medication as well.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Ampicillin Sodium Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Ampicillin Sodium Injection?

Ampicillin Sodium Injection is currently on the FDA shortage list. This report comes from one manufacturer, Sandoz Inc., and reflects their supply only — not every company that makes this medicine.

For the strengths covered in this report — the 1 g, 2 g, and 10 g — none have an available source from the filing manufacturer right now. The reason listed is a discontinuation of the private-label product. Because this is a discontinuation, this particular supply may not return, which makes a conversation with your prescriber or pharmacist the right next step. Keep in mind the same medicine is still listed from other makers, so your pharmacy may be able to track it down from another source.

Here is how to approach this:

  1. Do not stop, skip, or change how your medicine is used on your own.
  2. Ask your pharmacy to check wholesalers and other manufacturers — the same ampicillin sodium injection (including 1 g, 2 g, and 10 g) is listed from makers such as Sagent Pharmaceuticals and WG Critical Care, though it may not be in local stock.
  3. If your exact product cannot be found, ask your prescriber or pharmacist about options, such as a different strength or a clinician-chosen alternative.

Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle these calls. This is general, national information and may not match your local pharmacy's actual stock.

See “Where else can I get Ampicillin Sodium Injection?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Ampicillin guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Ampicillin guide →

Where else can I get Ampicillin Sodium Injection?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Ampicillin Sodium Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Ampicillin AMPICILLIN SODIUM 125 mg/1 Injection, Powder, For Solution · Intramuscular, Intravenous Sandoz Inc 00781-3400-95
Ampicillin AMPICILLIN SODIUM 250 mg/1 Injection, Powder, For Solution · Intramuscular, Intravenous Sandoz Inc 00781-3402-95
Ampicillin AMPICILLIN SODIUM 1 g/1 Injection, Powder, For Solution · Intramuscular, Intravenous Sandoz Inc 00781-3404-95
Ampicillin AMPICILLIN SODIUM 500 mg/1 Injection, Powder, For Solution · Intramuscular, Intravenous Sandoz Inc 00781-3407-95
Ampicillin AMPICILLIN SODIUM 2 g/1 Injection, Powder, For Solution · Intramuscular, Intravenous Sandoz Inc 00781-3408-95
Ampicillin AMPICILLIN SODIUM 10 g/1 Injection, Powder, For Solution · Intravenous Sandoz Inc 00781-3409-95
Ampicillin AMPICILLIN SODIUM 1 g/1 Injection, Powder, For Solution · Intramuscular, Intravenous Sagent Pharmaceuticals 25021-0136-10
Ampicillin AMPICILLIN SODIUM 2 g/1 Injection, Powder, For Solution · Intramuscular, Intravenous Sagent Pharmaceuticals 25021-0137-20
Ampicillin Sodium AMPICILLIN SODIUM 10 g/100mL Injection, Powder, For Solution · Intravenous Sagent Pharmaceuticals 25021-0197-99
Ampicillin AMPICILLIN SODIUM 250 mg/1 Injection, Powder, For Solution · Intramuscular, Intravenous WG Critical Care, LLC 44567-0100-10
Ampicillin AMPICILLIN SODIUM 500 mg/1 Injection, Powder, For Solution · Intramuscular, Intravenous WG Critical Care, LLC 44567-0101-10
Ampicillin AMPICILLIN SODIUM 1 g/1 Injection, Powder, For Solution · Intramuscular, Intravenous WG Critical Care, LLC 44567-0102-10

Alternative dosage forms of Ampicillin Sodium

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 30 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Ampicillin 2 gNDC 00404-9818-99 Henry 1 vial — AP FDA listed
Ampicillin 2 gNDC 00781-3408-95 Sandoz 10 vials — AP FDA listed
Ampicillin 2 gNDC 00781-3413-92 Sandoz 10 vials — — FDA listed
Ampicillin 2 gNDC 00781-9273-95 Sandoz 10 vials — AP FDA listed
Ampicillin 2 gNDC 00781-9408-95 Sandoz 10 vials — AP FDA listed
Ampicillin 2 gNDC 00781-9413-92 Sandoz 10 vials — — FDA listed
Ampicillin 2 g/2gNDC 23155-0917-41 Heritage 10 vials — AP FDA listed
ampicillin 2 gNDC 25021-0137-20 Sagent 10 vials — AP FDA listed
Ampicillin 2 gNDC 44567-0103-10 WG 10 vials — AP FDA listed
Ampicillin 2 gNDC 51662-1560-03 HF 10 pouches — AP FDA listed
Ampicillin 2 gNDC 55150-0114-20 Eugia 10 vials — AP FDA listed
Ampicillin 2 gNDC 65219-0020-23 Fresenius 10 vials — AP FDA listed
Ampicillin 2 gNDC 71872-7139-01 Medical 1 vial — AP FDA listed
Ampicillin 2 gNDC 71872-7240-01 Medical 1 vial — AP FDA listed
Ampicillin sodium 2 gNDC 71872-7342-01 Medical 1 vial — AP FDA listed
Ampicillin sodium 2 gNDC 72485-0422-10 Armas 10 vials — AP FDA listed
Ampicillin 2 gNDC 72572-0017-10 Civica, 10 vials — AP FDA listed
Ampicillin sodium 2 gNDC 72572-0094-10 Civica, 10 vials — AP FDA listed
Ampicillin 2 gNDC 72603-0454-10 NorthStar 10 vials — AP FDA listed
Ampicillin 2 gNDC 83270-0314-10 ONESOURCE 10 vials — AP FDA listed
Ampicillin 1 gNDC 00781-3404-95 Sandoz 10 vials — AP FDA listed
Ampicillin 1 gNDC 00781-3412-92 Sandoz 10 vials — — FDA listed
Ampicillin 1 gNDC 00781-9261-95 Sandoz 10 vials — AP FDA listed
Ampicillin 1 gNDC 00781-9404-95 Sandoz 10 vials — AP FDA listed
Ampicillin 1 gNDC 00781-9412-92 Sandoz 10 vials — — FDA listed
Ampicillin 1 g/gNDC 23155-0916-41 Heritage 10 vials — AP FDA listed
ampicillin 1 gNDC 25021-0136-10 Sagent 10 vials — AP FDA listed
Ampicillin 1 gNDC 44567-0102-10 WG 10 vials — AP FDA listed
Ampicillin 1 gNDC 55150-0113-10 Eugia 10 vials — AP FDA listed
Ampicillin 1 gNDC 65219-0018-10 Fresenius 10 vials — AP FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Ampicillin Sodium Injection — that fall in the same broad treatment class (penicillin antibiotics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 059863
GCN 25775
HICL code 003952
Ingredient (HICL) Ampicillin Sodium
HIC1 code W
Therapeutic class — broad (HIC1) Anti-Infecting Agents
HIC2 code W1
Therapeutic class — intermediate (HIC2) Antibiotics
HIC3 code W1A
Therapeutic class — specific (HIC3) Penicillin Antibiotics
AHFS code 08:12.16.08
AHFS class Aminopenicillin Antibiotics
FDB label name AMPICILLIN 2 GM ADD-VANTAGE VL
FDB brand name Ampicillin Sodium
Legend status F — Federal legend — prescription drug or device
GPI-1401200020302127
GPI classAmpicillin Sodium
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other anti-infective shortages

Ampicillin Sodium Injection shortage FAQs

Is Ampicillin Sodium Injection in shortage?
Yes — the FDA currently lists Ampicillin Sodium Injection in shortage (status: “To Be Discontinued”, first reported Dec 8, 2025). 5 of 5 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Ampicillin Sodium, Injection, 2 g (NDC 0781-9413-92) (NDC 00781-9413-92); Ampicillin Sodium, Injection, 2 g (NDC 0781-9408-95) (NDC 00781-9408-95); Ampicillin Sodium, Injection, 1 g (NDC 0781-9404-95) (NDC 00781-9404-95). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Ampicillin Sodium Injection be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Ampicillin Sodium somewhere?
Other manufacturers (Sandoz Inc, Sagent Pharmaceuticals, WG Critical Care, LLC) still market it and have not reported a shortage. 3 alternative dosage forms of Ampicillin Sodium are also listed. See “Where else can I get Ampicillin Sodium Injection?” above — stock still varies by pharmacy.
What should I do if I take Ampicillin Sodium Injection?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Ampicillin Sodium Injection shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
← Back to all current drug shortages