Pilocarpine Hydrochloride Ophthalmic Solution shortage
Pilocarpine Hydrochloride Ophthalmic Solution is currently listed in shortage by the FDA. The FDA lists 5 affected products. This page was last refreshed from FDA data on Oct 4, 2026.
AbbVie is permanently stopping its pilocarpine hydrochloride eye drops (12.5 mg/mL). Other manufacturers not reporting a shortage still list pilocarpine hydrochloride eye drops in multiple strengths, including 12.5 mg/mL.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Pilocarpine Hydrochloride Ophthalmic Solution. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Mar 24, 2026Currently in shortage5 of 5 products affected.
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Mar 24, 2026First reported to the FDA5 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: AbbVie Inc. 📞 800-633-9110 5 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | Vuity, Ophthalmic Solution, 12.5 mg/1 mL (NDC 0074-7098-05) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Vuity, Ophthalmic Solution, 12.5 mg/1 mL (NDC 0074-7098-03) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Vuity, Ophthalmic Solution, 12.5 mg/1 mL (NDC 0074-7098-04) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Vuity, Ophthalmic Solution, 12.5 mg/1 mL (NDC 0074-7098-06) | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Vuity, Ophthalmic Solution, 12.5 mg/1 mL (NDC 0074-7098-01) | — | — | Discontinuation of the manufacture of the drug | — |
These rows are manufacturer reports to the FDA for Pilocarpine Hydrochloride Ophthalmic Solution — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Pilocarpine Hydrochloride Ophthalmic Solution? options further down this page.
Why is Pilocarpine Hydrochloride Ophthalmic Solution in shortage?
AbbVie has reported to the FDA that it is permanently stopping the manufacturing of Vuity (pilocarpine hydrochloride ophthalmic solution, 12.5 mg/1 mL) across all of its package sizes. This means AbbVie will no longer be making this specific product going forward. No specific reason was shared publicly as to why they made this decision.
It's worth knowing that this report reflects only what AbbVie has filed with the FDA — it covers their Vuity brand specifically, not every version of pilocarpine eye drops that may exist from other manufacturers.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Pilocarpine Hydrochloride Ophthalmic Solution, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Pilocarpine Hydrochloride Ophthalmic Solution?
Pilocarpine hydrochloride ophthalmic solution (the eye drop sold as Vuity, 12.5 mg/1 mL) is currently on the FDA shortage list. I want to walk you through what this means so you can plan your next steps calmly.
The one strength covered by this report, 12.5 mg/1 mL, has no available source right now. The reason listed is that the manufacturer, AbbVie, is discontinuing production of this product. Because this is a discontinuation rather than a temporary delay, this particular supply problem may be permanent. That makes a conversation with your prescriber the right next step.
The good thing to keep in mind is that pilocarpine itself is still made by other companies in different strengths and forms. Please don't make any changes to your drops on your own first.
- Do not stop or change your eye drops without guidance from your pharmacist or prescriber.
- Ask your pharmacy whether the same ingredient from another maker (for example, Amneal, Sandoz, Somerset, or Orasis products) could work for you — these may need ordering and may not be in local stock.
- Ask your prescriber or pharmacist about the best option for your specific condition.
Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls. This is national data and may not match your local pharmacy's actual stock.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Pilocarpine Hydrochloride Ophthalmic Solution?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Pilocarpine Hydrochloride Ophthalmic Solution is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Pilocarpine Hydrochloride Ophthalmic | PILOCARPINE HYDROCHLORIDE 12.5 mg/mL | Solution/ Drops · Ophthalmic | Amneal Pharmaceuticals NY LLC | 60219-2366-02 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 10 mg/mL | Solution/ Drops · Ophthalmic | Sandoz Inc | 61314-0203-15 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 20 mg/mL | Solution/ Drops · Ophthalmic | Sandoz Inc | 61314-0204-15 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 40 mg/mL | Solution/ Drops · Ophthalmic | Sandoz Inc | 61314-0206-15 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 10 mg/mL | Solution/ Drops · Ophthalmic | Amneal Pharmaceuticals NY LLC | 69238-1745-08 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 20 mg/mL | Solution/ Drops · Ophthalmic | Amneal Pharmaceuticals NY LLC | 69238-1746-08 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 40 mg/mL | Solution/ Drops · Ophthalmic | Amneal Pharmaceuticals NY LLC | 69238-1747-08 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 10 mg/mL | Solution/ Drops · Ophthalmic | Somerset Therapeutics, LLC | 70069-0181-01 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 20 mg/mL | Solution/ Drops · Ophthalmic | Somerset Therapeutics, LLC | 70069-0191-01 |
| Pilocarpine Hydrochloride | PILOCARPINE HYDROCHLORIDE 40 mg/mL | Solution/ Drops · Ophthalmic | Somerset Therapeutics, LLC | 70069-0201-01 |
| Qlosi | PILOCARPINE HYDROCHLORIDE 4 mg/mL | Solution · Ophthalmic | Orasis Pharmaceuticals, Inc. | 83661-0018-10 |
Alternative dosage forms of Pilocarpine Hydrochloride
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 5 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Pilocarpine Hydrochloride Ophthalmic 12.5 mg/mL | Amneal | 1 bottle | $19.391 | — | Availability likely |
| Pilocarpine Hydrochloride Ophthalmic 12.5 mg/mL | Amneal | 1 bottle | $24.740 | — | Availability likely |
| Vuity 12.5 mg/mL | AbbVie | 1 bottle | $31.394 | — | Discontinued |
| Vuity 12.5 mg/mL | AbbVie | 1 bottle | — | — | Discontinued |
| Vuity 12.5 mg/mL | AbbVie | 3 bottles | — | — | Discontinued |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Pilocarpine Hydrochloride Ophthalmic Solution — that fall in the same broad treatment class (miotics and other intraocular pressure reducers) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other ophthalmology shortages
Pilocarpine Hydrochloride Ophthalmic Solution shortage FAQs
Is Pilocarpine Hydrochloride Ophthalmic Solution in shortage?
Which products are affected?
When will Pilocarpine Hydrochloride Ophthalmic Solution be available again?
Can I still get Pilocarpine Hydrochloride somewhere?
What should I do if I take Pilocarpine Hydrochloride Ophthalmic Solution?
Still have a question about the Pilocarpine Hydrochloride Ophthalmic Solution shortage?
Ask a pharmacist about this shortage →View Pilocarpine Hydrochloride Ophthalmic Sol... on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.