Echothiophate Iodide Ophthalmic Solution shortage
Echothiophate Iodide Ophthalmic Solution is currently listed in shortage by the FDA. The FDA lists 1 affected product. The reported reason: Other. This page was last refreshed from FDA data on Sep 22, 2026.
Echothiophate iodide eye drops are in shortage, but the 0.125% strength is still available. Fera Pharmaceuticals supplies it through limited distribution at Walgreens Specialty Pharmacy.
Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers and your prescriber about a long-term plan.
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Echothiophate Iodide Ophthalmic Solution. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Sep 1, 2026Currently in shortage1 of 1 product affected.
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Sep 24, 2019First reported to the FDA1 product first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Fera Pharmaceuticals 📞 516-277-1449 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Phospholine Iodide, Ophthalmic Solution, 0.125% (NDC 48102-053-05) | — | Available | Available through limited distribution by Walgreens Specialty Pharmacy. | Other |
These rows are manufacturer reports to the FDA for Echothiophate Iodide Ophthalmic Solution — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Echothiophate Iodide Ophthalmic Solution? options further down this page.
Why is Echothiophate Iodide Ophthalmic Solution in shortage?
Echothiophate iodide ophthalmic solution 0.125% from Fera Pharmaceuticals (brand name Phospholine Iodide) is on the shortage list, though the manufacturer hasn't shared a specific public reason beyond a general "other" category. What we do know is that this particular product is still being made and is currently available — but it's only being distributed through a limited channel, specifically Walgreens Specialty Pharmacy.
So while it's not gone, access is restricted compared to what you might expect from a typical medication. The shortage listing reflects that not everyone can easily get it through their usual pharmacy.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Echothiophate Iodide Ophthalmic Solution, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Echothiophate Iodide Ophthalmic Solution?
Echothiophate iodide ophthalmic solution (also sold as Phospholine Iodide) is currently on the FDA drug-shortage list. This has been an ongoing situation for over a year, but the medicine does still have an available source, so I want to walk you through what that means for you.
The only strength involved here is the 0.125% eye drops, and that strength does have supply. There is no strength of this medicine that is completely without a source right now. One manufacturer is reporting available stock, distributed in a limited way through Walgreens Specialty Pharmacy. The reason on file is listed only as "Other," and there is no recovery date attached because supply is currently flowing through that specialty channel rather than typical wholesalers.
Because this drug moves through limited distribution, your regular pharmacy may not have it on the shelf and may need to direct your prescription to the specialty pharmacy.
Here are the steps I'd suggest:
- Do not stop, skip, or change your dose on your own.
- Ask your pharmacy to order the 0.125% strength, which still has supply.
- Since it's limited distribution, your pharmacy may route it through Walgreens Specialty Pharmacy.
- If it can't be filled, ask your prescriber or pharmacist about your options.
A manufacturer contact number is listed on this page for reference; pharmacies usually make these calls.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Therapeutic equivalents & pricing 1 productclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Phospholine Iodide | Fera | 1 kit | — | — | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Echothiophate Iodide Ophthalmic Solution — that fall in the same broad treatment class (miotics and other intraocular pressure reducers) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other ophthalmology shortages
Echothiophate Iodide Ophthalmic Solution shortage FAQs
Is Echothiophate Iodide Ophthalmic Solution in shortage?
Why is Echothiophate Iodide Ophthalmic Solution in shortage?
Which products are affected?
When will Echothiophate Iodide Ophthalmic Solution be available again?
What should I do if I take Echothiophate Iodide Ophthalmic Solution?
Still have a question about the Echothiophate Iodide Ophthalmic Solution shortage?
Ask a pharmacist about this shortage →View Echothiophate Iodide Ophthalmic Solution on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.