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Isocarboxazid Tablet shortage

Isocarboxazid Tablet is currently listed in shortage by the FDA. The FDA lists 1 affected product. The reported reason: Other. This page was last refreshed from FDA data on Oct 2, 2026.

Current ⚠ Supply risk: Medium Psychiatry 1 product 169 days First posted Apr 16, 2026 Updated Aug 6, 2026
Here’s the bottom line

Isocarboxazid (Marplan) 10 mg tablets are currently in shortage, though the one manufacturer on record, Lifsa Drugs, still lists some supply available. No other makers of this medicine are on file, so availability may be limited.

Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers and your prescriber about a long-term plan.

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
1
Affected NDCs
1
Reporting manufacturers
1/1
Reporting mfrs supplying
1/1
Affected strengths supplied
0%
NDCs unavailable
169
Days in shortage
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 2, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Isocarboxazid Tablet. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
1 NDCs
Limited 1
Affected strengths still supplied
Among manufacturers reporting this shortage
1/1 strengths
Sourceable 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
1/1 makers
With supply 1
Other manufacturers
We couldn’t automatically confirm other manufacturers of Isocarboxazid Tablet that aren’t reporting a shortage. Ask your pharmacist whether a different manufacturer or strength can be ordered.
Shortage timeline
  1. Aug 6, 2026
    Currently in shortage
    1 of 1 product affected.
  2. Apr 16, 2026
    First reported to the FDA
    1 product first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Lifsa Drugs LLC 📞 833.627.0070 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
Current Marplan, Tablet, 10 mg, 100 count bottle (NDC 72336-032-01) NDC 72336-0032-01 — Limited Availability Estimated recovery: TBD Other

These rows are manufacturer reports to the FDA for Isocarboxazid Tablet — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Isocarboxazid Tablet? options further down this page.

Why is Isocarboxazid Tablet in shortage?

Right now, the 10 mg Isocarboxazid (Marplan) tablets — specifically the 100-count bottle made by Lifsa Drugs LLC — are in limited supply. The FDA has this listed under the reason category of "Other," which basically means the specific cause of the shortage hasn't been publicly shared. Unfortunately, Lifsa Drugs LLC also hasn't given a timeline for when things will get back to normal — their estimated recovery date is listed as "to be determined."

So to put it simply, we know there's a supply problem with this particular product from this manufacturer, but we don't yet know exactly why or when it will be resolved. That's not a lot of information, I know, and I wish I could give you more details — but that's all that's been reported to the FDA at this time.

FDA reason code(s): Other

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Isocarboxazid Tablet, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Isocarboxazid Tablet?

Isocarboxazid tablets are currently on the FDA drug-shortage list. If you take this medicine, please keep taking it as prescribed while supply steadies.

This medicine comes in one strength, 10 mg, and that strength still has an available source. The manufacturer on this record, Lifsa Drugs LLC, reports it as limited availability, so your pharmacy may need a little extra time to order it. No strength is listed as completely unavailable right now.

The reported reason is listed only as "Other," and an estimated recovery date has not yet been set. One manufacturer is currently supplying this medicine, so it has not stopped being made — it is simply harder to get in the short term.

Here are practical steps you can take:

  • Do not stop, skip, or change your dose on your own.
  • Ask your pharmacy to order the 10 mg tablets; they can check wholesalers and manufacturers for available stock.
  • If your pharmacy cannot locate it soon, ask your prescriber or pharmacist about your options rather than going without.
  • Manufacturer contact numbers are listed on this page for reference, though your pharmacy usually handles those calls.

This is general, national information from FDA data and may not match your local pharmacy's stock, so please check with them directly.

If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Isocarboxazid guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Isocarboxazid guide →
Therapeutic equivalents & pricing 1 productclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Marplan 10 mgNDC 72336-0032-01 Lifsa 100 tablets — — FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Isocarboxazid Tablet — that fall in the same broad treatment class (maois -non-selective,irreversible antidepressants) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 046262
GCN 16416
HICL code 001638
Ingredient (HICL) Isocarboxazid
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H7
Therapeutic class — intermediate (HIC2) Psychoactive Drugs (Continued 1)
HIC3 code H7J
Therapeutic class — specific (HIC3) Maois -Non-Selective,Irreversible Antidepressants
AHFS code 28:16.04.12
AHFS class Monoamine Oxidase Inhibitors
FDB label name MARPLAN 10 MG TABLET
FDB brand name Marplan
Legend status F — Federal legend — prescription drug or device
GPI-1458100010000305
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other psychiatry shortages

Isocarboxazid Tablet shortage FAQs

Is Isocarboxazid Tablet in shortage?
Yes — the FDA currently lists Isocarboxazid Tablet in shortage (status: “Current”, first reported Apr 16, 2026). 1 of 1 product is affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Why is Isocarboxazid Tablet in shortage?
The manufacturer-reported reason on file with the FDA: Other.
Which products are affected?
Marplan, Tablet, 10 mg, 100 count bottle (NDC 72336-032-01) (NDC 72336-0032-01). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Isocarboxazid Tablet be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
What should I do if I take Isocarboxazid Tablet?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Isocarboxazid Tablet shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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