Home › NDC Lookup › Drug shortages › Dextrose Monohydrate 50% Injection

Dextrose Monohydrate 50% Injection shortage

Dextrose Monohydrate 50% Injection is currently listed in shortage by the FDA. The FDA lists 4 affected products. The reported reason: Other. This page was last refreshed from FDA data on Oct 2, 2026.

Current ⚠ Supply risk: Medium Endocrinology/Metabolism, Gastroenterolo... 4 products 2 manufacturers 1,723 days · 4.7 yr First posted Jan 13, 2022 Updated Sep 22, 2026
Here’s the bottom line

Dextrose 50% injection (dextrose monohydrate) is in a lasting shortage, with one strength — the 0.5 g/mL ABBOJECT® glass syringe — having no available source from reporting makers. Other strengths, including 25 g/50 mL, are still listed by ICU Medical and RemedyRepack.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
4
Affected NDCs
2
Reporting manufacturers
2/2
Reporting mfrs supplying
1/2
Affected strengths supplied
0%
NDCs unavailable
1,723
Days in shortage
3,521
Medicaid Rx (2025)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 2, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Dextrose Monohydrate 50% Injection. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
4 NDCs
Available 2 Limited 1 To be discontinued 1
Affected strengths still supplied
Among manufacturers reporting this shortage
1/2 strengths
Sourceable 1 No supply 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
2/2 makers
With supply 2
✓ Other manufacturers not reporting a shortage
Still-marketed Dextrose Monohydrate 50% Injection from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
ICU Medical Inc. REMEDYREPACK INC.
See all other options & details →
Shortage timeline
  1. Sep 22, 2026
    Currently in shortage
    4 of 4 products affected.
  2. Sep 16, 2026
    FDA refreshed this shortage record
    1 product updated.
  3. Aug 24, 2026
    FDA refreshed this shortage record
    1 product updated.
  4. Nov 7, 2025
    FDA refreshed this shortage record
    1 product updated.
  5. Nov 7, 2025
    More presentations reported
    1 more product added to the shortage.
  6. Jan 13, 2022
    First reported to the FDA
    3 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Amphastar Pharmaceuticals, Inc. 📞 800-423-4136 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
Current Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 76329-3302-1) NDC 76329-3302-01 — Available — —
Manufacturer: Hospira, Inc., a Pfizer Company 📞 844-646-4398 3 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
Current Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 0409-7517-16) NDC 00409-7517-16 — Available — —
Current Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 0409-6648-02) NDC 00409-6648-02 — Limited Availability Next Delivery: November 2026; Estimated Recovery: December 2026. Shortage per Manufacturer: Manufacturing Delay Other
To Be Discontinued Dextrose Monohydrate 50%, Injection, 50% Dextrose Injection 0.5 g/mL; ABBOJECT® Glass Syringe (NDC 0409-4902-34) NDC 00409-4902-34 — — Discontinuation of the manufacture of the drug —

These rows are manufacturer reports to the FDA for Dextrose Monohydrate 50% Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Dextrose Monohydrate 50% Injection? options further down this page.

Why is Dextrose Monohydrate 50% Injection in shortage?

For one of Hospira/Pfizer's versions of this product — the 25 g/50 mL vial (NDC 0409-6648-02) — there's been a hold-up at their manufacturing facility, which has limited how much is available right now. According to Hospira, they expect their next delivery in November 2026, with supply expected to recover by December 2026. It's worth knowing that Hospira's other 25 g/50 mL presentation (NDC 0409-7517-16) is currently available from them, and Amphastar's 25 g/50 mL version is available as well.

Hospira is also permanently stopping production of their 50% Dextrose ABBOJECT® Glass Syringe (0.5 g/mL). That specific package — the prefilled glass syringe format — is being discontinued by the manufacturer, meaning they don't plan to make it again. The FDA listed the overall reason category as "Other," so beyond what's noted above, Hospira hasn't shared additional public details about what caused the manufacturing delay.

FDA reason code(s): Other

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Dextrose Monohydrate 50% Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Dextrose Monohydrate 50% Injection?

Dextrose Monohydrate 50% Injection is currently on the FDA shortage list. If you or the person you care for uses this medicine, the supply picture depends on which form you take, and I want to walk you through it clearly.

The 25 g/50 mL vial still has an available source — both manufacturers on this record report supply, though one delivery is running behind, with an estimated recovery around December 2026. The older 50% Dextrose 0.5 g/mL ABBOJECT® glass syringe, however, is listed as being discontinued by its manufacturer, so that particular form may not return. The overall reason reported to the FDA is listed only as "other," and this shortage has lasted more than a year.

Here is what I suggest, in order:

  • Do not stop, skip, or change your dose on your own.
  • If you use the 25 g/50 mL form, ask your pharmacy to order it — they can check wholesalers and both manufacturers.
  • The same medicine is also made by ICU Medical and RemedyRepack; your pharmacy may be able to source one of these, though it may not be in local stock.
  • If your exact form (the ABBOJECT® syringe) cannot be found, talk with your prescriber or pharmacist about a suitable option.

Manufacturer contact numbers are listed on this page for reference, though pharmacies usually handle those calls. This is general, national data and may not match your local pharmacy's stock.

See “Where else can I get Dextrose Monohydrate 50% Injection?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Dextrose guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Dextrose guide →

Where else can I get Dextrose Monohydrate 50% Injection?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Dextrose Monohydrate 50% Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Dextrose DEXTROSE MONOHYDRATE 50 g/100mL Injection, Solution · Intravenous ICU Medical Inc. 00990-7936-19
Dextrose DEXTROSE MONOHYDRATE 25 g/50mL Injection, Solution · Intravenous REMEDYREPACK INC. 70518-4219-00
Therapeutic equivalents & pricing 15 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Dextrose 25 g/50mLNDC 00404-9845-50 Henry 1 syringe — — FDA listed
Dextrose 25 g/50mLNDC 00409-7517-16 Hospira, 1 syringe — — FDA listed
50% Dextrose 25 g/50mLNDC 51662-1216-01 HF 1 syringe — — FDA listed
Dextrose Monohydrate 25 g/50mLNDC 51662-1453-01 HF 1 syringe — — Discontinued
Dextrose monohydrate 25 g/50mLNDC 51662-1584-01 HF 1 syringe — AP FDA listed
Dextrose 25 g/50mLNDC 70518-4219-00 REMEDYREPACK 1 syringe — — FDA listed
Dextrose 25 g/50mLNDC 71872-7003-01 Medical 1 syringe — — FDA listed
Dextrose 25 g/50mLNDC 71872-7102-01 Medical 1 syringe — — FDA listed
Dextrose Monohydrate 25 g/50mLNDC 71872-7282-01 Medical 1 syringe — AP FDA listed
Dextrose Monohydrate 25 g/50mLNDC 76329-3302-01 International 1 syringe — AP FDA listed
Dextrose 25 g/50mLNDC 84549-0517-16 ProPharma 50 ml — — FDA listed
Dextrose 25 g/50mLNDC 71872-7057-01 Medical 1 vial — — FDA listed
Dextrose 25 g/50mLNDC 00404-9847-50 Henry 1 vial — — FDA listed
Dextrose 25 g/50mLNDC 00409-6648-02 Hospira, 25 vials — — FDA listed
Dextrose 25 g/50mLNDC 51662-1215-01 HF 50 ml — — FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Dextrose Monohydrate 50% Injection — that fall in the same broad treatment class (iv solutions: dextrose-water) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 001989
GCN 06771
HICL code 000926
Ingredient (HICL) Dextrose 50 % In Water
HIC1 code C
Therapeutic class — broad (HIC1) Electrolyte Balance/Metabolism/Nutrition
HIC2 code C5
Therapeutic class — intermediate (HIC2) Carbohydrates And/Or Proteins
HIC3 code C5J
Therapeutic class — specific (HIC3) Iv Solutions: Dextrose-Water
AHFS code 40:20.00.00
AHFS class Caloric Agents
FDB label name DEXTROSE 50%-WATER SYRINGE
FDB brand name Dextrose In Water
Legend status F — Federal legend — prescription drug or device
GPI-1480100020002050
GPI classDextrose
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other endocrinology/metabolism, gastroenterology, pediatric shortages

Dextrose Monohydrate 50% Injection shortage FAQs

Is Dextrose Monohydrate 50% Injection in shortage?
Yes — the FDA currently lists Dextrose Monohydrate 50% Injection in shortage (status: “Current”, first reported Jan 13, 2022). 4 of 4 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Why is Dextrose Monohydrate 50% Injection in shortage?
The manufacturer-reported reason on file with the FDA: Other.
Which products are affected?
Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 76329-3302-1) (NDC 76329-3302-01); Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 0409-7517-16) (NDC 00409-7517-16); Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 0409-6648-02) (NDC 00409-6648-02). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Dextrose Monohydrate 50% Injection be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Dextrose Monohydrate 50% somewhere?
Other manufacturers (ICU Medical Inc., REMEDYREPACK INC.) still market it and have not reported a shortage. See “Where else can I get Dextrose Monohydrate 50% Injection?” above — stock still varies by pharmacy.
What should I do if I take Dextrose Monohydrate 50% Injection?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Dextrose Monohydrate 50% Injection shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
← Back to all current drug shortages