Progesterone Vaginal Gel shortage
Progesterone Vaginal Gel is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Oct 2, 2026.
AbbVie is permanently stopping production of Crinone (progesterone vaginal gel) 4%. No other makers of this gel are currently listed as having supply available.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Progesterone Vaginal Gel. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Mar 27, 2026Currently in shortage1 of 1 product affected.
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Mar 27, 2026First reported to the FDA1 product first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: AbbVie Inc. 📞 800-678-1605 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | Crinone, Vaginal Gel, 4% (NDC 0023-6150-04) | — | — | Discontinuation of the manufacture of the drug | — |
These rows are manufacturer reports to the FDA for Progesterone Vaginal Gel — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Progesterone Vaginal Gel? options further down this page.
Why is Progesterone Vaginal Gel in shortage?
AbbVie has reported to the FDA that they are permanently stopping the manufacture of Crinone (progesterone vaginal gel, 4%). That's the specific product affected here — no particular reason for the decision was shared publicly, just that production is ending for good.
It's worth knowing that this report only covers AbbVie's version of this product. Other manufacturers may still make progesterone vaginal gel, and those would be listed separately on this page.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Progesterone Vaginal Gel, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Progesterone Vaginal Gel?
Progesterone vaginal gel (4%) is currently on the FDA drug-shortage list, and I want to walk you through what that means for you.
This shortage affects the 4% strength, which is the only strength on this record. There is no available source reported for it right now. The manufacturer, AbbVie, has listed the product (Crinone, 4%) as being discontinued, which means this supply problem may be permanent rather than a short-term gap. Because the reason given is discontinuation of manufacture, a conversation with your prescriber is the right next step.
Please keep this in mind, in order:
- Do not stop, skip, or change your doses on your own.
- Ask your pharmacy to check with their wholesalers, since local stock can differ from national reports and some supply may still be found.
- If your pharmacy cannot locate the 4% gel, talk with your prescriber or pharmacist about a clinician-chosen option that fits your needs.
- Manufacturer contact numbers are listed on this page for reference, though your pharmacy usually handles those calls.
This information comes from national, manufacturer-reported FDA data and is general, not personal medical advice. Your care team can help you decide what is best for you.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Progesterone Vaginal Gel?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Progesterone Vaginal Gel is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Alternative dosage forms of Progesterone
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 1 productclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Crinone 45 mg/1.125g | Allergan, | 6 applicators | $16.844 | — | Availability likely |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Progesterone Vaginal Gel — that fall in the same broad treatment class (progestational agents) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other urology shortages
Progesterone Vaginal Gel shortage FAQs
Is Progesterone Vaginal Gel in shortage?
Which products are affected?
When will Progesterone Vaginal Gel be available again?
Can I still get Progesterone somewhere?
What should I do if I take Progesterone Vaginal Gel?
Still have a question about the Progesterone Vaginal Gel shortage?
Ask a pharmacist about this shortage →View Progesterone Vaginal Gel on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.