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Medroxyprogesterone Acetate Tablet shortage

Medroxyprogesterone Acetate Tablet is currently listed in shortage by the FDA. The FDA lists 2 affected products. This page was last refreshed from FDA data on Oct 3, 2026.

To Be Discontinued ⚠ Supply risk: High Urology 2 products 33 days First posted Aug 31, 2026 Updated Aug 31, 2026
Here’s the bottom line

Pfizer is stopping production of medroxyprogesterone acetate tablets, with withdrawal from sale expected by late 2026. Other makers still list this medicine — including Provera (medroxyprogesterone acetate) — so it may be available from other sources.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
2
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/2
Affected strengths supplied
33
Days in shortage
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 3, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Medroxyprogesterone Acetate Tablet. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
2 NDCs
To be discontinued 2
Affected strengths still supplied
Among manufacturers reporting this shortage
0/2 strengths
No supply 2
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Medroxyprogesterone Acetate Tablet from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Pharmacia & Upjohn Company LLC Teva Pharmaceuticals USA, Inc. A-S Medication Solutions PD-Rx Pharmaceuticals, Inc. Mylan Pharmaceuticals Inc. American Health Packaging
Plus 7 alternative dosage forms of Medroxyprogesterone Acetate.
See all other options & details →
Shortage timeline
  1. Aug 31, 2026
    Currently in shortage
    2 of 2 products affected.
  2. Aug 31, 2026
    First reported to the FDA
    2 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Pfizer Inc. 📞 800-533-4535 2 NDCS click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued PROVERA, Tablet, 2.5 mg (NDC 0009-0065-01) NDC 00009-0065-01 — — Discontinuation of the manufacture of the drug; Withdrawal from sale expected early October 2026. —
To Be Discontinued PROVERA, Tablet, 10 mg (NDC 0009-0051-01) NDC 00009-0051-01 — — Discontinuation of the manufacture of the drug; Withdrawal from sale expected September 2026. —

These rows are manufacturer reports to the FDA for Medroxyprogesterone Acetate Tablet — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Medroxyprogesterone Acetate Tablet? options further down this page.

Why is Medroxyprogesterone Acetate Tablet in shortage?

Pfizer has let the FDA know that they are permanently stopping the manufacturing of their brand-name version of this medication, Provera. This affects two specific strengths: the 10 mg tablets, which Pfizer expects to pull from sale around September 2026, and the 2.5 mg tablets, which are expected to be withdrawn from sale in early October 2026. No specific reason was shared publicly for why Pfizer made this decision — just that they are discontinuing production of these particular products.

It's worth knowing that this report only covers Pfizer's Provera tablets. Other manufacturers may make their own versions of medroxyprogesterone acetate and are listed separately on this page.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Medroxyprogesterone Acetate Tablet, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Medroxyprogesterone Acetate Tablet?

Medroxyprogesterone acetate tablets are currently listed on the FDA shortage report, and I want to walk you through what that means for you.

The report covers both the 2.5 mg and 10 mg tablets, and neither strength has an available source from the manufacturer that filed this record (Pfizer, maker of the brand Provera). The reason listed is that this manufacturer is discontinuing production — the 10 mg is expected to be withdrawn from sale around September 2026, and the 2.5 mg around early October 2026. Because this is a discontinuation, the supply problem from this maker may be permanent, which makes a conversation with your prescriber the right next step.

This report reflects only one manufacturer, and the same medicine is still made by other companies. Please don't make any changes on your own.

  • Do not stop, skip, or change your dose on your own.
  • Ask your pharmacy to check wholesalers and other makers — the same medicine (medroxyprogesterone acetate) is listed from Teva and Mylan in 2.5 mg and 10 mg, though it may not be in local stock.
  • If your exact tablet can't be found, ask your prescriber or pharmacist about options.

Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls. This is national, manufacturer-reported data and may not match your local pharmacy's actual stock.

See “Where else can I get Medroxyprogesterone Acetate Tablet?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Medroxyprogesterone guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Medroxyprogesterone guide →

Where else can I get Medroxyprogesterone Acetate Tablet?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Medroxyprogesterone Acetate Tablet is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Provera MEDROXYPROGESTERONE ACETATE 5 mg/1 Tablet · Oral Pharmacia & Upjohn Company LLC 00009-0287-01
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 10 mg/1 Tablet · Oral Teva Pharmaceuticals USA, Inc. 00555-0779-02
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 2.5 mg/1 Tablet · Oral Teva Pharmaceuticals USA, Inc. 00555-0872-02
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 5 mg/1 Tablet · Oral Teva Pharmaceuticals USA, Inc. 00555-0873-02
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 10 mg/1 Tablet · Oral A-S Medication Solutions 50090-0166-00
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 2.5 mg/1 Tablet · Oral A-S Medication Solutions 50090-0490-02
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 5 mg/1 Tablet · Oral A-S Medication Solutions 50090-0491-01
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 10 mg/1 Tablet · Oral PD-Rx Pharmaceuticals, Inc. 55289-0160-05
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 2.5 mg/1 Tablet · Oral Mylan Pharmaceuticals Inc. 59762-0055-01
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 10 mg/1 Tablet · Oral Mylan Pharmaceuticals Inc. 59762-0056-01
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 5 mg/1 Tablet · Oral Mylan Pharmaceuticals Inc. 59762-0058-01
Medroxyprogesterone Acetate MEDROXYPROGESTERONE ACETATE 10 mg/1 Tablet · Oral American Health Packaging 60687-0105-21

Alternative dosage forms of Medroxyprogesterone Acetate

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 22 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Medroxyprogesterone Acetate 2.5 mgNDC 00555-0872-02 Teva 100 tablets $0.116 AB Availability likely
medroxyprogesterone acetate 2.5 mgNDC 59762-0055-01 Mylan 100 tablets $0.116 AB Availability likely
Medroxyprogesterone Acetate 10 mgNDC 00555-0779-02 Teva 100 tablets $0.152 AB Availability likely
medroxyprogesterone acetate 10 mgNDC 59762-0056-01 Mylan 100 tablets $0.152 AB Availability likely
Medroxyprogesterone Acetate 10 mgNDC 60687-0105-21 American 30 tablets $0.152 AB Availability likely
Provera 2.5 mgNDC 00009-0065-01 Pharmacia 100 tablets — AB FDA listed
Medroxyprogesterone Acetate 2.5 mgNDC 50090-0490-00 A-S 10 tablets — AB Discontinued
Medroxyprogesterone Acetate 2.5 mgNDC 63629-8825-01 Bryant 100 tablets — AB FDA listed
Medroxyprogesterone Acetate 2.5 mgNDC 67046-1480-03 Coupler 30 tablets — AB FDA listed
Medroxyprogesterone Acetate 2.5 mgNDC 70518-4666-00 REMEDYREPACK 50 tablets — AB FDA listed
Medroxyprogesterone Acetate 2.5 mgNDC 72789-0043-30 PD-Rx 30 tablets — AB FDA listed
Provera 10 mgNDC 00009-0051-01 Pharmacia 100 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 50090-0166-00 A-S 10 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 51655-0520-52 Northwind 30 tablets — AB FDA listed
Medroxyprogesterone 10 mgNDC 54348-0805-05 PharmPak, 5 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 55289-0160-05 PD-Rx 5 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 63187-0382-10 Proficient 10 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 63629-2612-01 Bryant 10 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 63629-8824-01 Bryant 100 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 68071-4132-01 NuCare 10 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 68788-9899-01 Preferred 10 tablets — AB FDA listed
Medroxyprogesterone Acetate 10 mgNDC 70518-3070-01 REMEDYREPACK 30 tablets — AB Discontinued

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Medroxyprogesterone Acetate Tablet — that fall in the same broad treatment class (progestational agents) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 003272
GCN 11261
HICL code 001442
Ingredient (HICL) Medroxyprogesterone Acetate
HIC1 code G
Therapeutic class — broad (HIC1) Female Genital System
HIC2 code G2
Therapeutic class — intermediate (HIC2) Progestogens
HIC3 code G2A
Therapeutic class — specific (HIC3) Progestational Agents
AHFS code 68:32.00.00
AHFS class Progestins
FDB label name PROVERA 2.5 MG TABLET
FDB brand name Provera
Legend status F — Federal legend — prescription drug or device
GPI-1426000020200305
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other urology shortages

Medroxyprogesterone Acetate Tablet shortage FAQs

Is Medroxyprogesterone Acetate Tablet in shortage?
Yes — the FDA currently lists Medroxyprogesterone Acetate Tablet in shortage (status: “To Be Discontinued”, first reported Aug 31, 2026). 2 of 2 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
PROVERA, Tablet, 2.5 mg (NDC 0009-0065-01) (NDC 00009-0065-01); PROVERA, Tablet, 10 mg (NDC 0009-0051-01) (NDC 00009-0051-01). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Medroxyprogesterone Acetate Tablet be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Medroxyprogesterone Acetate somewhere?
Other manufacturers (Pharmacia & Upjohn Company LLC, Teva Pharmaceuticals USA, Inc., A-S Medication Solutions and others) still market it and have not reported a shortage. 7 alternative dosage forms of Medroxyprogesterone Acetate are also listed. See “Where else can I get Medroxyprogesterone Acetate Tablet?” above — stock still varies by pharmacy.
What should I do if I take Medroxyprogesterone Acetate Tablet?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Medroxyprogesterone Acetate Tablet shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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