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Zanosar (Streptozocin) Powder for Solution shortage

Zanosar (streptozocin powders for solution) is on the FDA’s drug shortage list as of Oct 5, 2026. The companies reporting it blame reasons the companies did not specify.

Current ⚠ Supply risk: High Oncology 2 products 2 companies reporting 1,547 days · 4.2 yr First posted Jul 12, 2022 Updated Sep 16, 2026
Here’s the bottom line

Streptozocin powder for solution is currently in shortage, with the 100 mg/1 mL concentration having no available source right now. The 1 g/10 mL strength still has a listed supply from one manufacturer.

Don’t stop or change your therapy on your own — ask your pharmacist about other companies’ versions and your prescriber about a long-term plan.

Do you take this medicine? See the ‘What to do’ note from Dr. Brian Staiger, PharmD →
2
Affected NDCs
1/2
Reporting makers with supply
1/2
Affected strengths still listed
1,547
Days on the list
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Oct 5, 2026 · yesterday

Is Zanosar still in shortage? — status as of Oct 5, 2026

Yes, still current as of Oct 5, 2026. 1 of the 2 strengths is still made by at least one company; 1 is not. 1 of the 2 companies that reported this shortage says it still has some supply, and no other company sells the same medicine. Your pharmacy may still need to order it or offer another company’s version.

⚠ Supply risk: High 5 of 5 risk factors
  1. Every strength is still listed by a company — 1 of 2 strengths
  2. More than one company still lists it — 1 of 2 reporting companies with supply
  3. Most affected NDCs still available — 50% unavailable
  4. Not a long-running shortage — 1,546 days
  5. Listed by several companies — 2 companies (2 reporting)

A rule-based estimate of national supply risk, counting both the companies reporting the shortage and the companies listing the same medicine without a report — never your local pharmacy’s stock. How the rating works.

The charts count only the companies that reported this shortage to the FDA; we could not confirm another company listing it (see below).

Availability of affected NDCs
From the FDA shortage report
2 NDCs
Available 1 Unavailable 1
Affected strengths still listed by a company
A reporting maker with supply, or another company listing that strength
1/2 strengths
Has a listed source 1 No listed source 1
Reporting companies with supply
Among the 2 companies that reported this shortage
1/2 reporting
Reporting supply 1 Reporting no supply 1
Other companies
We couldn’t confirm another company listing Streptozocin Powder for Solution in the FDA NDC Directory without a shortage report. Ask your pharmacist whether a different company’s version or another strength can be ordered.
Shortage timeline
  1. Sep 16, 2026
    Currently in shortage
    2 of 2 products affected.
  2. Sep 15, 2026
    FDA refreshed this shortage record
    1 product updated.
  3. Jul 12, 2022
    First reported to the FDA
    2 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

Which Zanosar products are affected — by company

Company: ESTEVE PHARMACEUTICALS, S.A. 📞 [email protected] 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
Current Zanosar Powder for Solution, 1 g/10 mL NDC 68118-0100-01 1 g/10 mL Available — —
Company: Teva Pharmaceuticals USA, Inc. 📞 800-545-8800 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
Current Zanosar Powder for Solution, 100 mg/1 mL NDC 00703-4636-01 100 mg/1 mL Unavailable Estimated recovery: TBD Other

These rows are company reports to the FDA for Streptozocin Powder for Solution — they do not cover every company that lists this medicine. A company appears here only if it told the FDA it has a supply problem, so other companies may still have stock.

Why is Zanosar in shortage?

A note from Dr. Brian Staiger, PharmD · Written Oct 4, 2026

Right now, the 100 mg/1 mL vial of Zanosar (streptozocin) made by Teva Pharmaceuticals is unavailable. Unfortunately, Teva hasn't shared a specific public reason for the shortage beyond classifying it as "other," so I can't tell you exactly what's causing the hold-up on their end. There's also no estimated recovery date yet — it's listed as "TBD," meaning to be determined.

The good news is that this report only covers Teva's specific 100 mg/1 mL presentation. The 1 g/10 mL vial of Zanosar from ESTEVE Pharmaceuticals is currently listed as available, so that strength and package size is not affected by this shortage.

FDA reason code(s): Other

Based on the company-reported reason(s) and notes on file with the FDA for Streptozocin Powder for Solution, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as companies report changes.

What should I do if I take Zanosar?

A note from Dr. Brian Staiger, PharmD · Written Oct 4, 2026

Streptozocin (also sold as Zanosar) is currently on the FDA drug-shortage list, and I want to walk you through what that means for your treatment.

There are two strengths on this record, and they are in different situations right now. The 1 g/10 mL strength still has an available source from a manufacturer. The 100 mg/1 mL strength has no available source at this time, with an estimated recovery date listed as to-be-determined.

The reported reason is listed only as "other," so there is no further detail on the cause. One of the two manufacturers on this record is still supplying the 1 g/10 mL strength, and this shortage has been ongoing for over a year. That is a long stretch, but it also means pharmacies have had time to learn how to work around it.

Here is what I suggest:

  • Do not stop, skip, or change your dose on your own.
  • If you take the 1 g/10 mL strength, ask your pharmacy to order it — they can check wholesalers and manufacturers for you.
  • If your exact strength cannot be found, ask your prescriber or pharmacist about options, such as using an available strength to make up the dose.

Manufacturer contact numbers are listed on this page for reference, though your pharmacy usually handles these calls. This is national data and may not match your local pharmacy's stock.

Quick checklist for the pharmacy counter:
  • Ask your pharmacy to check other companies’ versions, other strengths, package sizes, and nearby stores.
  • If this is part of an ongoing or essential regimen (for example HIV, seizure, heart, transplant, diabetes or mental-health medicines), arrange continued supply before you run out rather than rationing doses.
Keep reading
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Read the Cetirizine guide →
Therapeutic equivalents & pricing 4 productsclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Quzyttir 10 mg/mLNDC 68118-0100-01 ESTEVE 1 vial — — Discontinued
Quzyttir 10 mg/mLNDC 70720-0100-10 TerSera 1 vial — — FDA listed
Quzyttir 10 mg/mLNDC 68118-0200-10 ESTEVE 1 vial — — FDA listed
Zanosar 100 mg/mLNDC 00703-4636-01 Teva 10 ml — — Discontinued

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Zanosar — that fall in the same broad treatment class (antibiotic antineoplastics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Codes & classification for pharmacists and billers
GCN Seq No 008825
GCN 38630
HICL code 003920
Ingredient (HICL) Streptozocin
HIC1 code V
Therapeutic class — broad (HIC1) Neoplasms
HIC2 code V1
Therapeutic class — intermediate (HIC2) Antineoplastic Drugs
HIC3 code V1D
Therapeutic class — specific (HIC3) Antibiotic Antineoplastics
AHFS code 10:00.00.00
AHFS class Antineoplastic Agents
FDB label name ZANOSAR 1 GM VIAL
FDB brand name Zanosar
Legend status F — Federal legend — prescription drug or device
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

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Zanosar shortage FAQs

Is Zanosar still in shortage?
Yes — as of Oct 5, 2026 the FDA lists Zanosar (streptozocin powders for solution) as a current shortage (status: “Current”, first reported Jul 12, 2022). The FDA’s record for this shortage covers 2 products from 2 companies. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which strengths of Zanosar are affected?
The FDA record covers 2 strengths: 1 g/10 mL, 100 mg/1 mL. No listed source right now: 100 mg/1 mL. Every other strength on the record is still listed by someone — a reporting maker with supply, or another company listing it with the FDA.
Why is Zanosar in shortage?
The companies reporting it told the FDA the cause is reasons the companies did not specify.
Which Zanosar products are affected?
Zanosar Powder for Solution, 1 g/10 mL (NDC 68118-0100-01); Zanosar Powder for Solution, 100 mg/1 mL (NDC 00703-4636-01). The full per-NDC list (availability, company and status) is in the table above — each NDC links to its own page.
When will Zanosar be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Is the brand or the generic affected?
Only the brand (Zanosar) is on this FDA record; it lists no generic streptozocin powders for solution. Availability can still differ between companies and package sizes — check the per-NDC table and confirm with your pharmacy.
What should I do if I take Zanosar?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another company or a different strength or package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Zanosar shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (0–2)Several companies still list it and most strengths or pack sizes are still listed by someone — counting both the companies reporting the shortage and the companies listing the same medicine without a report. A listing is not a stock check.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes without a source, or a long-running outage. A company’s discontinuation notice is not an outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (companies listing the same ingredient & form — the "other companies" the rating counts); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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