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Aspirin Suppository shortage

Aspirin Suppository is currently listed in shortage by the FDA. The FDA lists 1 affected product. This page was last refreshed from FDA data on Sep 22, 2026.

To Be Discontinued ⚠ Supply risk: High Analgesia/Addiction, Cardiovascular 1 product 62 days First posted Jul 23, 2026 Updated Jul 23, 2026
Here’s the bottom line

Padagis is permanently stopping production of aspirin suppositories (300 mg). No other manufacturer is currently listed as a source for this product.

Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
1
Affected NDCs
1
Reporting manufacturers
0/1
Reporting mfrs supplying
0/1
Affected strengths supplied
62
Days in shortage
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Sep 22, 2026 · yesterday

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Aspirin Suppository. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
1 NDCs
To be discontinued 1
Affected strengths still supplied
Among manufacturers reporting this shortage
0/1 strengths
No supply 1
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
0/1 makers
No supply 1
✓ Other manufacturers not reporting a shortage
Still-marketed Aspirin Suppository from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Plus 22 alternative dosage forms of Aspirin.
See all other options & details →
Shortage timeline
  1. Jul 23, 2026
    Currently in shortage
    1 of 1 product affected.
  2. Jul 23, 2026
    First reported to the FDA
    1 product first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Padagis US LLC 📞 (800) 775-2054 1 NDC click to expand
Status NDC / product Strength Availability Related information Reason
To Be Discontinued Aspirin, Suppository, 300 mg (NDC 0574-7034-12) NDC 00574-7034-12 Discontinuation of the manufacture of the drug

These rows are manufacturer reports to the FDA for Aspirin Suppository — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Aspirin Suppository? options further down this page.

Why is Aspirin Suppository in shortage?

Padagis US LLC has reported to the FDA that they are permanently stopping the manufacture of their 300 mg aspirin suppositories (the 12-count package). That's the reason this product appears on the shortage list — it's not a temporary delay or a supply hiccup, but a full discontinuation of that specific product by this manufacturer.

It's worth knowing that Padagis did not share a more detailed reason for why they made this decision — just that they are stopping production of it. No specific reason was provided in the FDA report beyond the discontinuation itself.

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Aspirin Suppository, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Aspirin Suppository?

Aspirin suppositories, 300 mg, are currently listed on the FDA drug-shortage report. I want to walk you through what this means so you can plan your next steps calmly.

The only strength on this record is the 300 mg suppository, and it does not have an available source right now. The manufacturer that filed this report, Padagis US LLC, lists the reason as a discontinuation of the manufacture of the drug. Because this is marked "to be discontinued," this supply problem may be permanent rather than temporary. No other maker is listed on this record, so I don't have a same-medicine option to point you to here.

Please keep in mind this information comes from national, manufacturer-reported data and may not match what any single pharmacy has on its shelves.

Here is what I suggest, in order:

  • Do not stop, skip, or change how you use this medicine on your own.
  • Because this strength is being discontinued, ask your prescriber or pharmacist about options — for example a clinician-chosen alternative that fits your needs.
  • Your pharmacy can also check wholesalers and other manufacturers to see whether any supply remains.
  • The manufacturer's contact number is listed on this page for reference; pharmacies usually handle those calls.

A short conversation with your prescriber is the right next step.

See “Where else can I get Aspirin Suppository?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Aspirin Rectal guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Aspirin Rectal guide →

Where else can I get Aspirin Suppository?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Aspirin Suppository is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Alternative dosage forms of Aspirin

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 1 productclick to expand

Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
aspirin 300 mgNDC 00574-7034-12 Padagis 12 suppositories FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Aspirin Suppository — that fall in the same broad treatment class (analgesic/antipyretics, salicylates) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 004371
GCN 16696
HICL code 001820
Ingredient (HICL) Aspirin
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H3
Therapeutic class — intermediate (HIC2) Analgesics
HIC3 code H3D
Therapeutic class — specific (HIC3) Analgesic/Antipyretics, Salicylates
AHFS code 20:12.18.00
AHFS class Platelet-Aggregation Inhibitors
FDB label name ASPIRIN 300 MG SUPPOSITORY
FDB brand name Aspirin
Legend status O — Over-the-counter (OTC) drug or device
GPI-1464100010005218
GPI classAspirin
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Aspirin Suppository shortage FAQs

Is Aspirin Suppository in shortage?
Yes — the FDA currently lists Aspirin Suppository in shortage (status: “To Be Discontinued”, first reported Jul 23, 2026). 1 of 1 product is affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Which products are affected?
Aspirin, Suppository, 300 mg (NDC 0574-7034-12) (NDC 00574-7034-12). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Aspirin Suppository be available again?
The FDA does not publish a guaranteed restock date, and no estimated-recovery note is on file. Availability can change daily — confirm with your pharmacy.
Can I still get Aspirin somewhere?
22 alternative dosage forms of Aspirin are also listed. See “Where else can I get Aspirin Suppository?” above — stock still varies by pharmacy.
What should I do if I take Aspirin Suppository?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Aspirin Suppository shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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