Desmopressin Acetate Spray shortage
Desmopressin Acetate Spray is currently listed in shortage by the FDA. The FDA lists 4 affected products. The reported reason: Requirements related to complying with good manufacturing practices. This page was last refreshed from FDA data on Sep 22, 2026.
Desmopressin acetate nasal spray has been in shortage for over a year, with most strengths currently unavailable from any maker. Only the 10 mcg strength still has a listed supply, and Ferring has no recovery date set.
Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers (see options) and your prescriber about a long-term plan.
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Desmopressin Acetate Spray. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Sep 16, 2026Currently in shortage4 of 4 products affected.
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May 1, 2026FDA refreshed this shortage record3 products updated.
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Mar 12, 2021First reported to the FDA4 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Apotex Corp. 📞 800-706-5575 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Desmopressin Acetate (needs No Refrigeration), Spray, 10 ug (NDC 60505-0815-0) | — | Available | — | — |
Manufacturer: Ferring 📞 888-337-7464 3 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Desmopressin Acetate, Spray, 10 ug/.1 mL (NDC 69918-501-05) | — | Unavailable | Estimated recovery: TBD | Requirements related to complying with good manufacturing pr... |
| Current | Ddavp, Spray, .1 ug/1 mL (NDC 55566-2500-0) | — | Unavailable | Estimated recovery: TBD | Requirements related to complying with good manufacturing pr... |
| Current | Stimate, Spray, 1.5 mg/1 mL (NDC 0053-6871-00) | — | Unavailable | Estimated recovery: TBD | Requirements related to complying with good manufacturing pr... |
These rows are manufacturer reports to the FDA for Desmopressin Acetate Spray — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Desmopressin Acetate Spray? options further down this page.
Why is Desmopressin Acetate Spray in shortage?
Ferring Pharmaceuticals has three versions of desmopressin acetate nasal spray that are currently unavailable — Stimate (1.5 mg/1 mL), DDAVP (0.1 mcg/1 mL), and their generic desmopressin acetate (10 mcg/0.1 mL) — because Ferring is working to meet FDA manufacturing quality standards, sometimes called "good manufacturing practices." These are the rules the FDA sets to make sure medicines are made safely and consistently, and when a company needs to come into compliance with them, production can be paused.
Unfortunately, Ferring has not yet given an estimated date for when these products will be back in supply — all three are listed as "TBD," meaning to be determined. It's worth knowing that this shortage report reflects only Ferring's products; other manufacturers may have their own listings elsewhere.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Desmopressin Acetate Spray, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Desmopressin Acetate Spray?
Desmopressin Acetate Spray is currently on the FDA shortage list, and I want to walk you through what that means for the strength you use.
The picture depends on which strength you take. The 10 ug spray is still available from a manufacturer right now. Three other strengths do not have an available source at this time: the 1.5 mg/1 mL spray (Stimate), the .1 ug/1 mL spray (Ddavp), and the 10 ug/.1 mL spray. For each of those, the estimated recovery is listed as to-be-determined.
The reported reason involves requirements tied to good manufacturing practices. One of the two manufacturers on this record is still supplying, and this shortage has lasted over a year, so it may take time to fully resolve.
Here is what I suggest:
- Do not stop, skip, or change your dose on your own.
- If you use the 10 ug spray, ask your pharmacy to order it — they can check wholesalers and other manufacturers.
- If your strength is one of the unavailable ones, ask your prescriber or pharmacist about options, such as adjusting to reach your dose or a clinician-chosen alternative.
- Manufacturer contact numbers are listed on this page for reference; your pharmacy usually makes these calls.
This is national, manufacturer-reported data and may not match your local pharmacy's actual stock.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Desmopressin Acetate Spray?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Desmopressin Acetate Spray is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Alternative dosage forms of Desmopressin Acetate
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 3 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Desmopressin Acetate 10 ug | Apotex | 1 bottle | $9.282 | AB | Availability likely |
| Desmopressin Acetate .1 mg/mL | Bauch | 1 bottle | $23.917 | AB | FDA listed |
| Desmopressin Acetate .1 mg/mL | Oceanside | 1 bottle | — | AB | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Desmopressin Acetate Spray — that fall in the same broad treatment class (antidiuretic and vasopressor hormones) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other hematology shortages
Desmopressin Acetate Spray shortage FAQs
Is Desmopressin Acetate Spray in shortage?
Why is Desmopressin Acetate Spray in shortage?
Which products are affected?
When will Desmopressin Acetate Spray be available again?
Can I still get Desmopressin Acetate somewhere?
What should I do if I take Desmopressin Acetate Spray?
Still have a question about the Desmopressin Acetate Spray shortage?
Ask a pharmacist about this shortage →View Desmopressin Acetate Spray on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.