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Desmopressin

Desmopressin is a man-made version of the body's antidiuretic hormone, used for central diabetes insipidus, bleeding disorders (hemophilia A and von Willebrand’s disease Type I), and, in tablet form, bedwetting (primary nocturnal enuresis).

Brand names DdavpStimateNoctivaNocdurnaDesmoda
Drug classes Factor Viii Activator
Rx Forms 4
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 23 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

Other forms & routes:
Nasal
Desmopressin at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Desmopressin is a man-made copy of the body's antidiuretic hormone that makes the kidneys hold on to water and raises clotting factor VIII, so it is a long-standing first choice for central diabetes insipidus and is also used for mild to moderate hemophilia A, von Willebrand's disease Type I and, as tablets, bedwetting; it has been around since about 1982 and is available generically. Most people tolerate it well, with headache, nausea, flushing or (from the nasal spray) a stuffy nose the usual complaints. Its real danger is low blood sodium (hyponatremia), the subject of the injection's boxed warning, so stick to your fluid limit and keep your sodium checks.

Clinical pearls

  • Act fast on signs of low sodium, such as a bad headache, vomiting, confusion, muscle cramps or sudden weight gain.
  • Tell every prescriber you take it, since loop diuretics, steroids (even inhaled) and many antidepressants and pain medicines raise the sodium risk.
  • If a stomach bug, fever or anything else upsets your fluid balance, call your prescriber, since doses may need pausing.
  • Prime a new nasal spray pump before the first dose, and never swap between nasal, tablet and injection products on your own.
How we write & review this content — our editorial policy →
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

Desmopressin injection can cause dangerously low blood sodium (hyponatremia), which can be life-threatening. Severe cases can lead to seizures, coma, stopped breathing, or death.

The injection must not be used by people at higher risk, including those who drink too much fluid, have illnesses that upset fluid or salt balance, or take loop diuretics or steroids (systemic or inhaled). Sodium should be normal before starting, and checked within about a week, at about a month, and regularly after. People 65 and older and those at higher risk need more frequent checks. Treatment may need to be paused or stopped if sodium drops.

Read the full warning on DailyMed →
How you get itPrescription only
Comes asInjection, Tablet, Nasal spray +1
Earliest FDA record1978
Companies listing it with the FDA28
FDA label last updatedAug 27, 2026
FDA’s strongest warning (boxed)Yes, read the warning

Patient information guide A plain-language walkthrough of Desmopressin, written from its FDA label.

What Desmopressin is used for

▾

Desmopressin is used for several conditions, depending on the product.

  • Central diabetes insipidus: desmopressin acetate injection, Ddavp and Desmopressin Acetate tablets, Desmopressin Acetate nasal spray (ages 4 and up), and Desmoda oral solution.
  • Temporary heavy urination and thirst after head trauma or pituitary surgery: injection and tablets.
  • Hemophilia A (factor VIII above 5%): desmopressin acetate injection and Stimate nasal spray.
  • von Willebrand’s disease Type I (mild to moderate): desmopressin acetate injection and Stimate nasal spray.
  • Primary nocturnal enuresis (bedwetting): Ddavp and Desmopressin Acetate tablets.
  • Not for nephrogenic diabetes insipidus, severe Type I von Willebrand’s disease, or hemophilia B.

How Desmopressin works

▾

Desmopressin is a synthetic form of the hormone that tells the kidneys to hold on to water. It stimulates V2 receptors in the kidney, so more water is reabsorbed and less urine is made. Its structure was changed so it lasts longer and has far less effect on blood vessels and gut muscle. It also raises factor VIII activity, helping blood clot in hemophilia A and von Willebrand’s disease Type I.

Desmopressin dosage

▾

Dosing depends on the product and the condition.

  • Injection: under the skin or into a vein; for bleeding disorders, a diluted intravenous infusion.
  • Nasal spray: sprayed into the nose after priming the pump.
  • Tablets: taken by mouth, adjusted to your response.

Your prescriber will tailor the dose. Ask them about fluid limits and what to do if you miss a dose.

Dosing details from the FDA-approved label

From the Desmopressin prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Diabetes Insipidus (treatment naïve patients)
    • Recommended starting daily dosage is 2 mcg to 4 mcg administered as one or two divided doses by subcutaneous or intravenous injection
    • Do not dilute for the Diabetes Insipidus population
    • Morning and evening doses should be separately adjusted
    • Adjust dose based upon response (adequate duration of sleep and adequate, not excessive, water turnover)
    • Initiate fluid restriction during treatment
  • Diabetes Insipidus (patients changing from intranasal desmopressin)
    • Recommended starting dose is 1/10th the daily maintenance intranasal dose administered by subcutaneous or intravenous injection as one or two divided doses
    • Dose should be titrated individually according to diuresis and serum sodium
  • Hemophilia A and von Willebrand's Disease (Type I)
    • 0.3 mcg/kg actual body weight administered by intravenous infusion over 15 minutes to 30 minutes
    • If used preoperatively, administer 30 minutes prior to the procedure
    • If used to reduce spontaneous or traumatic bleeding, doses may be repeated after 8 hours to 12 hours and once daily thereafter, if needed, based upon clinical condition and von Willebrand fact
    • Maximum: 20 mcg
    • Dilute in 0.9% Sodium Chloride Injection, USP: 10 mL if 10 kg or less, 50 mL if more than 10 kg
Read the label’s full dosing text

2 DOSAGE AND ADMINISTRATION Diabetes Insipidus: The daily dose is 2 mcg to 4 mcg administered as one or two divided doses by subcutaneous or intravenous injection. The dosage must be determined for each patient and adjusted according to the pattern of response. ( 2.1 ) Hemophilia A and von Willebrand’s Disease (Type I): 0.3 mcg/kg (to a maximum of 20 mcg) administered by intravenous infusion. Dilute dose as appropriate. ( 2.1 ) See Full Prescribing Information for instructions on reconstitution, preparation, and administration ( 2 ). 2.1 Pretreatment Testing and On-Treatment Monitoring Diabetes Insipidus Prior to treatment with desmopressin acetate, assess serum sodium, urine volume and osmolality. Intermittently during treatment, assess serum sodium, urine volume and osmolality or plasma osmolality. Hemophilia A Prior to treatment with desmopressin acetate injection, verify that factor VIII coagulant activity levels are >5% and exclude the presence of factor VIII autoantibodies. Also assess serum sodium and aPTT prior to treatment. In certain clinical situations, it may be justified to try desmopressin acetate in patients with factor VIII levels between 2% to 5%; however, these patients should be carefully monitored. von Willebrand’s Disease (Type I) Prior to treatment with desmopressin acetate injection, verify that factor VIII coagulant activity levels are >5% and exclude severe von Willebrand’s disease (Type I) and presence of abnormal molecular form of factor VIII antigen. During treatment with desmopressin acetate injection, assess serum sodium, bleeding time, factor VIII coagulant activity, ristocetin cofactor activity, and von Willebrand antigen to ensure that adequate levels are being achieved. For All Patients Receiving Repeated Doses: Restrict free water intake and monitor for hyponatremia. Ensure that serum sodium is normal prior to initiating or resuming treatment with desmopressin acetate injection. 2.2 Recommended Dosage Initiate fluid restriction during treatment with desmopressin acetate injection [see Warnings and Precautions ( 5.1 ), Use in Specific Populations ( 8.4 , 8.5 )] . Diabetes Insipidus Treatment naïve patients: The recommended starting daily dosage is 2 mcg to 4 mcg administered as one or two divided doses by subcutaneous or intravenous injection.

Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →

Desmopressin side effects

▾

Reported side effects include:

Common side effects

  • Headache
  • Nausea
  • Stomach pain or cramps
  • Nasal congestion, runny nose or nosebleeds (nasal forms)
  • Flushing
  • Fast heartbeat
  • Eye redness
  • Dizziness

When to get medical help

  • Seek medical help for signs of low sodium (hyponatremia): severe headache, nausea or vomiting, confusion, weight gain, muscle cramps or weakness, or seizures.
  • Get emergency help for signs of a severe allergic reaction, such as trouble breathing or swelling.
  • Call your doctor if you have rapid weight gain or swelling from fluid retention.
  • Report significant changes in blood pressure or heart rate, or chest pain.
  • Tell your doctor if you have trouble passing urine.

Seek help for signs of low sodium, allergic reaction, or marked swelling or weight gain.

Desmopressin warnings and precautions

▾
  • Low blood sodium (hyponatremia) can be life-threatening. Limit fluids as directed and get sodium checked.
  • Blood pressure can rise or fall; monitoring matters especially with heart disease.
  • Serious allergic reactions, including anaphylaxis, have occurred.
  • Fluid retention can worsen heart failure or uncontrolled high blood pressure.
  • In Type IIB von Willebrand’s disease it may cause clots and low platelets.
  • Not recommended with a history of urinary retention or risk of raised pressure in the head.

Desmopressin interactions

▾

Some medicines raise the risk of low sodium or blood pressure effects.

  • Loop diuretics and systemic or inhaled glucocorticoids: must not be combined with the injection.
  • Antidepressants (tricyclics, SSRIs), NSAIDs, opiates, thiazides, carbamazepine, lamotrigine, chlorpromazine, sulfonylureas, oxybutynin: can add to sodium lowering, so more sodium checks are needed.
  • Other vasoconstrictors: may require a lower desmopressin dose.

Interactions listed in the FDA-approved label

From the Desmopressin prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Drugs that may increase risk of water intoxication with hyponatremia (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine): Concomitant use with desmopressin acetate injection may increase the risk of water intoxication with hyponatremia. Requires more frequent serum sodium monitoring, including when doses of these drugs are increased.
  • Other vasoconstrictors: Desmopressin acetate injection can elevate blood pressure, and use with other vasoconstrictors may require a reduction of its dosage. May require a reduction of the desmopressin acetate injection dosage.
Read the label’s full interactions text

7 DRUG INTERACTIONS Drugs that increase risk of hyponatremia: Require more frequent serum sodium monitoring. ( 7.1 ) Other vasoconstrictors: May require a reduction of the desmopressin acetate dosage. ( 7.2 ) 7.1 Other Drugs that may Increase Risk of Hyponatremia The concomitant administration of desmopressin acetate injection with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine), requires more frequent serum sodium monitoring. Monitor serum sodium more frequently in patients taking desmopressin acetate injection concomitantly with these drugs and when doses of these drugs are increased [see Contraindications ( 4 ), Warnings and Precautions ( 5.1 ), Drug Interactions ( 7.1 ), Use in Specific Populations ( 8.4 , 8.5 )]. 7.2 Other Vasoconstrictors Desmopressin acetate injection can elevate blood pressure. Use of desmopressin acetate injection with other vasoconstrictors may require a reduction of the desmopressin acetate injection dosage [see Warnings and Precautions ( 5.2 ), Adverse Reactions ( 6 )].

7.1 Other Drugs that may Increase Risk of Hyponatremia The concomitant administration of desmopressin acetate injection with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine), requires more frequent serum sodium monitoring.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

🌿17 supplements and herbs with documented Desmopressin interactions, ranked by severity Check Desmopressin against a supplement or herb →

Before taking Desmopressin

▾
  • Moderate to severe kidney impairment: the injection is contraindicated.
  • History of low sodium, SIADH, or heavy water drinking: the injection is contraindicated.
  • Heart failure or uncontrolled high blood pressure: the injection is contraindicated.
  • Illnesses causing fluid or salt imbalance, such as gastroenteritis or infection: avoid the injection.
  • Children and older adults: need careful fluid restriction. Older adults may need kidney monitoring.
  • Pregnancy: no drug-related risk identified with the injection.
  • Breastfeeding: only negligible amounts pass into breast milk.

Desmopressin overdose

▾

Too much desmopressin lasts longer and raises the risk of water retention and low sodium. Signs include headache, belly cramps, nausea, flushing, confusion, drowsiness, trouble passing urine, and rapid weight gain. The dose may be reduced, given less often, or stopped, sodium is checked, and low sodium is treated. There is no specific antidote.

What Desmopressin does in the body

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Stimate raises Factor VIII and von Willebrand factor to about 150 to 250 percent of starting levels, peaking at about 1.5 hours. In people with von Willebrand’s disease, levels stayed above 30 U/dL for 8 hours after a 300 mcg dose. The antidiuretic effect lowers urine volume and raises urine concentration. Tablets begin working at about 1 hour and peak at about 4 to 7 hours.

How your body processes Desmopressin

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Desmopressin injection has a terminal half-life of about 2.8 hours. It is not broken down by the CYP450 liver enzyme system. About 52% of an intravenous dose is cleared in urine unchanged within 24 hours. Kidney impairment slows clearance, raising drug levels. Tablets are absorbed at only a small fraction compared with the injection.

How to store Desmopressin

▾

Store refrigerated 2° to 8°C (36° to 46°F).

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

17

Supplements & herbs that interact with Desmopressin

17 supplements and herbal products have documented interactions with Desmopressin in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 1
  • Moderate · 7
  • Minor · 9
ACTIVATED CHARCOAL Major COFFEE CHARCOAL Moderate EUROPEAN MANDRAKE Moderate GLUCOMANNAN Moderate GUAR GUM Moderate GUM ARABIC Moderate SLIPPERY ELM Moderate TRAGACANTH Moderate +9 more
Every supplement checked against Desmopressin — ranked by severity The full interaction hub: 1 major · 7 moderate · 9 minor · every one linked to its full report. Check Desmopressin against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

Desmopressin: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Desmopressin — the kind of thing our pharmacy team would talk through with you at the counter.

What is desmopressin for?

▾
It depends on the product. It replaces the hormone that helps your body hold on to water in central diabetes insipidus. Some forms also treat hemophilia A and von Willebrand’s disease Type I, and the tablets are also used for bedwetting. Your prescriber chose the form that fits your condition.

Why do I need to limit how much I drink?

▾
Desmopressin makes your body hold on to water. Drinking too much can dilute the sodium in your blood, which can be dangerous. Ask your prescriber exactly how much fluid is right for you.

What side effects should I expect?

▾
Headache, nausea, stomach cramps, and flushing are possible. Nasal forms can cause a stuffy or runny nose or nosebleeds. Call right away for severe headache, confusion, vomiting, quick weight gain, swelling, or seizures.

Can I take it with my other medicines?

▾
Check with me first. Loop diuretics and steroids should not be combined with the injection. Antidepressants, NSAIDs, opioid pain relievers, and some seizure and water pills can also lower sodium, so you may need more blood tests.

Is it safe in pregnancy or while breastfeeding?

▾
Long experience with the injection hasn't shown a drug-related risk of birth defects or miscarriage. Only tiny amounts reach breast milk. Talk with your prescriber to weigh your own situation.

Who shouldn't use it?

▾
The injection isn't for people with moderate to severe kidney problems, past low sodium, heart failure, or uncontrolled high blood pressure. It also isn't for those who drink excessive fluids or have SIADH. Tell your prescriber about your full history.

Is Desmopressin available over the counter?

▾
No. Desmopressin is a prescription medicine: every Desmopressin product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Desmopressin first available?

▾
The earliest FDA record we hold for Desmopressin is from 1978: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Desmopressin was first used.

Who makes Desmopressin?

▾
28 companies currently list Desmopressin products in the FDA's NDC Directory, including Ferring Pharmaceuticals Inc., Nordic Pharma, Inc., Apotex Corp.. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Desmopressin on HelloPharmacist

📊Desmopressin supplement interactions17 checked — ranked by severity 🌿Drug & Supplement CheckerDesmopressin vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Desmopressin NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
Detailed data & references for Desmopressin Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Desmopressin forms and strengths (how it comes)

Desmopressin is available in 4 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Desmopressin inactive ingredients by manufacturer.

Injection

Into a vein · Under the skin
Brands Ddavp
How this form is used
What it may be used for
  • Desmopressin acetate injection is used for central diabetes insipidus and temporary urination and thirst after head trauma or pituitary surgery.
  • Desmopressin acetate injection is used for hemophilia A and von Willebrand’s disease (Type I).
  • Desmopressin acetate injection is not for nephrogenic diabetes insipidus.
Important instructions
  • For diabetes insipidus, desmopressin acetate injection is given once or twice daily under the skin or into a vein.
  • For hemophilia A and von Willebrand’s disease, it is given as a diluted intravenous infusion.
  • Fluid intake should be kept to a minimum from 1 hour before until 8 hours after desmopressin acetate injection.
  • Sodium is checked before treatment and during treatment.
Available strengths 2 strengths
4 mcg/mL 40 mcg/10 mL
44 FDA-listed product records ⓘ

Tablet

By mouth
Brands Ddavp
How this form is used
What it may be used for
  • Ddavp and Desmopressin Acetate tablets are used for central diabetes insipidus and temporary urination and thirst after head trauma or pituitary surgery.
  • Ddavp and Desmopressin Acetate tablets are used for primary nocturnal enuresis, alone or with behavioral conditioning.
  • Ddavp and Desmopressin Acetate tablets do not work for nephrogenic diabetes insipidus.
Important instructions
  • Desmopressin Acetate tablet dosing is individualized based on your response.
  • People switching from nasal desmopressin start tablets 12 hours after the last nasal dose.
  • Ddavp tablets come with fluid restriction advice, especially for children and older adults.
Available strengths 2 strengths
0.1 mg 0.2 mg
39 FDA-listed product records ⓘ

Nasal spray

In the nose
Brands Stimate
How this form is used
What it may be used for
  • Desmopressin Acetate nasal spray is used for central diabetes insipidus in adults and children 4 years and older.
  • Stimate is used for hemophilia A and von Willebrand’s disease (Type I).
  • Desmopressin Acetate nasal spray is not for nephrogenic diabetes insipidus or bedwetting.
Important instructions
  • Desmopressin Acetate nasal spray is for use in the nose only, and the pump must be primed before first use.
  • Desmopressin Acetate nasal spray comes with fluid restriction instructions.
  • Stimate is not used in infants younger than 11 months.
  • Stimate dosing depends on body weight.
Available strengths 3 strengths
10 mcg 0.1 mg/mL 1.5 mg/mL
10 FDA-listed product records ⓘ

Oral solution

By mouth
Brands Desmoda
How this form is used
What it may be used for
  • Desmoda is used for central diabetes insipidus in adults and children.
  • Desmoda is not for nephrogenic diabetes insipidus.
Available strengths 1 strength
0.05 mg/mL
1 FDA-listed product record ⓘ

Desmopressin on the U.S. market: products, makers and brands

How Desmopressin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

28 companies list 55 Desmopressin product records with the FDA, mostly as injection, tablet, nasal spray; the earliest marketing or approval year on record is 1978. Brand names on the directory include Ddavp, Stimate, Noctiva and 2 more; the rest are generics.

4
Dose forms ⓘ
28
Labelers (makers, repackagers, distributors)
4
Brand names
55
FDA-listed product records ⓘ
1978
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (30) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Ferring Pharmaceuticals Inc.9%
Nordic Pharma, Inc.7%
Apotex Corp.5%
UBI Pharma Inc.5%
American Health Packaging4%
Armas Pharmaceuticals Inc.4%
Other makers65%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Desmopressin is used (Medicaid data)

A general measure of how commonly Desmopressin is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Desmopressin is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

357,369
Medicaid prescriptions filled (Q1–Q4 2025)
$13.6M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Desmopressin prescribed? Of the 1,601 medications we measure, Desmopressin ranks #299 by Medicaid prescriptions — more than 81% of them.

Where Desmopressin ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #299 of 1,601
#294 Finasteride 375,944 Rx #295 Neomycin, Polymyxin, a... 367,823 Rx #296 Hydromorphone 367,041 Rx #297 Calcitriol 366,263 Rx #298 Enalapril 361,404 Rx #299 Desmopressin 357,369 Rx #300 Aripiprazole Injection 354,838 Rx #301 Emtricitabine and Teno... 354,223 Rx #302 Emtricitabine / Tenofo... 354,223 Rx #303 Vortioxetine 354,075 Rx #304 Azelastine Ophthalmic 347,051 Rx

Utilization by Desmopressin product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 0.2 mg oral tablet is the most-dispensed Desmopressin product — about 73% of these Medicaid prescriptions.

desmopressin acetate 0.2 MG Oral Tablet Most dispensed

259,634 Medicaid prescriptions (Q1–Q4 2025) 73% of Desmopressin prescriptions shown $8.9M gross reimbursement (before rebates) ≈ $34 per prescription (gross)

Summed across the 7 of 33 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 833008

desmopressin acetate 0.1 MG Oral Tablet

81,884 Medicaid prescriptions (Q1–Q4 2025) 23% of Desmopressin prescriptions shown $2.3M gross reimbursement (before rebates) ≈ $29 per prescription (gross)

Summed across the 5 of 26 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 849515

desmopressin acetate 0.01 MG/ACTUAT Nasal Spray

14,664 Medicaid prescriptions (Q1–Q4 2025) 4% of Desmopressin prescriptions shown $1.9M gross reimbursement (before rebates) ≈ $127 per prescription (gross)

Summed across the 3 of 9 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 849506

desmopressin acetate 0.004 MG/ML Injectable Solution

930 Medicaid prescriptions (Q1–Q4 2025) <1% of Desmopressin prescriptions shown $384,350 gross reimbursement (before rebates) ≈ $413 per prescription (gross)

Summed across the 5 of 21 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 849501

1 ML desmopressin acetate 0.004 MG/ML Injection

257 Medicaid prescriptions (Q1–Q4 2025) <1% of Desmopressin prescriptions shown $67,811 gross reimbursement (before rebates) ≈ $264 per prescription (gross)

Summed across the 6 of 26 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1723232

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Desmopressin, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 26 of 115 listed Desmopressin NDCs with Medicaid activity.

Compare Desmopressin products

A representative set of FDA-listed product records for Desmopressin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 55 of 55 products — FDA National Drug Code Directory. See every product, package size and price: browse all 55 Desmopressin NDCs →

Desmopressin recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list one Desmopressin recall since July 2021. It is no longer listed as ongoing. A recall names specific lots from one company, so check the lot number on your own bottle rather than assuming every product is affected; your pharmacist can check whether your supply came from an affected lot.

Class II Nov 23, 2022 · Terminated · Heritage Pharmaceuticals Inc
Subpotent Drug
  • Desmopressin Acetate Tablets 0.2mg, 100-count bottles, RX Only, Distributed by: Avet Pharmaceuticals Inc. East Brunswick, NJ 08816, NDC 23155-490-01 Lots: Lot #: 220440A, Exp. Date 05/2024 FDA record D-0072-2023 →

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Desmopressin RxCUI 3251 8 dose forms · 12 strengths
  1. Dose form (SCDF) Injectable Solution RxCUI 371714 In current FDA listings
    Clinical drug / strength (SCD) acetate 0.004 MG/ML RxCUI 849501
  3. Dose form (SCDF) Metered Dose Nasal Spray RxCUI 1797858 In current FDA listings
    Clinical drug / strength (SCD) acetate 0.00083 MG/ACTUAT RxCUI 1874124 acetate 0.00166 MG/ACTUAT RxCUI 1874132 acetate 0.15 MG/ACTUAT RxCUI 1797859
  4. Dose form (SCDF) Nasal Solution RxCUI 371715 In current FDA listings
    Clinical drug / strength (SCD) acetate 0.1 MG/ML RxCUI 849520
  5. Dose form (SCDF) Nasal Spray RxCUI 374371 In current FDA listings
    Clinical drug / strength (SCD) acetate 0.01 MG/ACTUAT RxCUI 849506
  6. Dose form (SCDF) Oral Solution RxCUI 2738080 In current FDA listings
    Clinical drug / strength (SCD) acetate 0.05 MG/ML RxCUI 2738083
  7. Dose form (SCDF) Oral Tablet RxCUI 371716 In current FDA listings
    Clinical drug / strength (SCD) acetate 0.1 MG RxCUI 849515 acetate 0.2 MG RxCUI 833008
  8. Dose form (SCDF) Sublingual Tablet RxCUI 2048571 No current FDA listing
    Clinical drug / strength (SCD) acetate 0.0277 MG RxCUI 2048716 acetate 0.0553 MG RxCUI 2048720

Look up RxCUI 3251 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Desmopressin costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet · Oral 0.2 mg $0.373 per tablet NDC details & price history
Tablet · Oral 0.1 mg $0.373 per tablet NDC details & price history
Injection, Solution · Intravenous, Subcutaneous 4 mcg/mL $19.15 per mL NDC details & price history
Injection, Solution · Intravenous, Subcutaneous 40 mcg/10 mL $19.15 per mL NDC details & price history
Solution · Nasal 0.1 mg/mL $23.92 per mL NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Desmopressin brand names

Desmopressin is sold under 5 brand names in the FDA directory — Ddavp, Stimate, Noctiva, Nocdurna and others. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Ddavp Stimate Noctiva Nocdurna Desmoda

Who makes Desmopressin: manufacturers and labelers

28 companies list Desmopressin products with the FDA. By number of product records, the largest are Ferring Pharmaceuticals Inc., Nordic Pharma, Inc., Apotex Corp.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Ferring Pharmaceuticals Inc. 5 Nordic Pharma, Inc. 4 Apotex Corp. 3 UBI Pharma Inc. 3 American Health Packaging 2 Armas Pharmaceuticals Inc. 2 Aurobindo Pharma Limited 2 BluePoint Laboratories 2 Bryant Ranch Prepack 2 Caplin Steriles Limited 2 Dr. Reddy's Laboratories Inc. 2 Fresenius Kabi USA, LLC 2 Gland Pharma Limited 2 Glenmark Pharmaceuticals Inc.,USA 2 Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 2 Kvk-tech, Inc. 2 Meitheal Pharmaceuticals Inc. 2 Sagent Pharmaceuticals 2 Sun Pharmaceutical Industries Limited 2 XGen Pharmaceuticals DJB, Inc. 2 Avenacy, Inc. 1 Bauch & Lomb Incorporated 1 Eton Pharmaceuticals, Inc. 1 Northwind Health Company, LLC 1

…and 4 more on the FDA NDC directory.

Desmopressin drug class (RxNorm)

Desmopressin belongs to the Vasopressin Analog class.

Pharmacologic class Vasopressin Analog, Factor VIII Activator
Drug family (ATC) Vasopressin and analogues

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Desmopressin page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Aug 27, 2026
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Desmopressin.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Desmopressin after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
23
Finished products in the current FDA directory
55
Companies listing them (makers, repackagers, distributors)
28
FDA labeler codes behind them ⓘ
29
Linked representative label ⓘ
The J. Molner Company LLC
Linked label effective
Aug 27, 2026
Composite sections available
22
Linked SPL Set ID
52680415-52a0-61c2-e063-6294a90ae27e
Linked SPL Document ID
5a144051-0656-4da5-e063-6294a90a18cf
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. The J. Molner Company LLC is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →