Aldactone (Spironolactone) Tablet shortage
Not a nationwide shortage — Pfizer has told the FDA it is discontinuing its spironolactone tablets. The FDA lists this under “To be discontinued” as of Oct 5, 2026: a company stopping its own product. 21 other companies sell the same medicine and have not reported a problem, so your pharmacy may be able to order another company’s version.
Pfizer is stopping production of spironolactone tablets, and this change may be permanent. The same medicine is still listed by other makers not reporting a shortage, including 25 mg, 50 mg, and 100 mg strengths.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this medicine? See the ‘What to do’ note from Dr. Brian Staiger, PharmD →Is Aldactone still in shortage? — status as of Oct 5, 2026
Still listed as “To be discontinued” as of Oct 5, 2026. Pfizer is stopping its own version only; 21 other companies still sell the same medicine and have not reported a problem. Your pharmacy may need to order another company’s version.
The charts count only the companies that reported this shortage to the FDA; companies that haven’t reported a problem are in the green card, and the Supply-Risk rating counts them too.
Shortage timeline
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Dec 10, 2025Currently in shortage2 of 2 products affected.
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Dec 10, 2025First reported to the FDA2 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
Which Aldactone products are affected — by company
Company: Pfizer Inc. 📞 800-533-4535 2 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| To Be Discontinued | Aldactone Tablet, 100 mg | 100 mg | — | Discontinuation of the manufacture of the drug. | — |
| To Be Discontinued | Aldactone Tablet, 25 mg | 25 mg | — | Discontinuation of the manufacture of the drug. | — |
These rows are company reports to the FDA for Spironolactone Tablet — they do not cover every company that lists this medicine. A company appears here only if it told the FDA it has a supply problem, so other companies may still have stock. That’s the basis for the Where else can I get Aldactone or its generic? options further down this page.
Why is Pfizer discontinuing Aldactone?
Pfizer has reported to the FDA that it is permanently stopping the manufacture of its brand-name version of spironolactone, sold as Aldactone. Specifically, the two affected products are the 25 mg tablets and the 100 mg tablets — both are being discontinued by Pfizer.
No specific reason was shared publicly by Pfizer for why they are making this decision — just that manufacturing of these products is ending. It's also worth noting that this report only reflects what Pfizer has filed with the FDA, and it applies only to their Aldactone brand. Other manufacturers of spironolactone are listed separately and may not be affected by this same decision.
Based on the company-reported reason(s) and notes on file with the FDA for Spironolactone Tablet, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as companies report changes.
What should I do if I take Aldactone?
Spironolactone tablets are currently on the FDA shortage list, so I want to walk you through what this means and the steps you can take.
The shortage record here applies to both the 25 mg and 100 mg tablets, and neither strength has an available source from the manufacturer that filed this report. The reason given is that this maker (Pfizer, under the brand name Aldactone) is discontinuing the manufacture of these tablets. Because this is a discontinuation rather than a short-term delay, the supply problem from this maker may be permanent, which makes a conversation with your prescriber or pharmacist the right next step.
It's important to know this report reflects only one manufacturer. Spironolactone is the same medicine made by several other companies, so it may still be available from another maker.
Here is what I suggest:
- Do not stop, skip, or change your dose on your own.
- Ask your pharmacy to source spironolactone from another maker — options on record include Mylan, Accord Healthcare, Camber, Major, and PD-Rx; your pharmacy can check wholesalers, though a given product may not be in local stock.
- If your exact tablet cannot be found, ask your prescriber or pharmacist about options.
Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls. This is general, national information and may not match your pharmacy's actual stock.
- Ask your pharmacy to check other companies’ versions, other strengths, package sizes, and nearby stores — the options below are a starting point.
- If this is part of an ongoing or essential regimen (for example HIV, seizure, heart, transplant, diabetes or mental-health medicines), arrange continued supply before you run out rather than rationing doses.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Aldactone or its generic?
FDA shortages are company-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every company that lists spironolactone tablets is necessarily short. Below are the other listings in the current FDA NDC Directory that are not reported in shortage: the same medicine from companies that haven’t reported a problem (the reporting company is excluded), and other dosage forms. These are generic versions of Aldactone — a switch from the brand goes through your pharmacist or prescriber. Some listings are repackagers, which relabel another company’s product. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine from other companies (not reporting a shortage)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from companies that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Company | NDC |
|---|---|---|---|---|
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Mylan Pharmaceuticals Inc. | 00378-0243-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Mylan Pharmaceuticals Inc. | 00378-0437-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Mylan Pharmaceuticals Inc. | 00378-2146-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Major Pharmaceuticals | 00904-6927-61 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Accord Healthcare, Inc. | 16729-0225-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Accord Healthcare, Inc. | 16729-0226-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Accord Healthcare, Inc. | 16729-0227-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Camber Pharmaceuticals, Inc. | 31722-0094-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Camber Pharmaceuticals, Inc. | 31722-0095-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Camber Pharmaceuticals, Inc. | 31722-0096-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | PD-Rx Pharmaceuticals, Inc. | 43063-0832-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | PD-Rx Pharmaceuticals, Inc. | 43063-0835-30 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | PD-Rx Pharmaceuticals, Inc. | 43063-0974-90 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | A-S Medication Solutions | 50090-0136-00 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | A-S Medication Solutions | 50090-3747-00 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Coated · Oral | A-S Medication Solutions | 50090-6369-00 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | A-S Medication Solutions | 50090-6408-00 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | A-S Medication Solutions | 50090-6432-00 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Coated · Oral | A-S Medication Solutions | 50090-6458-00 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Coated · Oral | A-S Medication Solutions | 50090-6539-00 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet · Oral | A-S Medication Solutions | 50090-7082-00 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Mylan Institutional Inc. | 51079-0103-20 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Mylan Institutional Inc. | 51079-0979-20 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Mylan Institutional Inc. | 51079-0980-08 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Northwind Health Company, LLC | 51655-0344-26 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | Sun Pharmaceutical Industries, Inc. | 53489-0143-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Sun Pharmaceutical Industries, Inc. | 53489-0328-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Sun Pharmaceutical Industries, Inc. | 53489-0329-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | Amneal Pharmaceuticals of New York LLC | 53746-0511-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet · Oral | Amneal Pharmaceuticals of New York LLC | 53746-0514-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet · Oral | Amneal Pharmaceuticals of New York LLC | 53746-0515-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | Aurobindo Pharma Limited | 59651-0426-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet · Oral | Aurobindo Pharma Limited | 59651-0427-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet · Oral | Aurobindo Pharma Limited | 59651-0428-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Jubilant Cadista Pharmacuticals Inc. | 59746-0216-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Jubilant Cadista Pharmacuticals Inc. | 59746-0217-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Jubilant Cadista Pharmacuticals Inc. | 59746-0218-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | American Health Packaging | 60687-0465-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet · Oral | American Health Packaging | 60687-0476-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet · Oral | American Health Packaging | 60687-0487-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Proficient Rx LP | 63187-0841-03 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | Bryant Ranch Prepack | 63629-1061-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Bryant Ranch Prepack | 63629-1065-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Bryant Ranch Prepack | 63629-1094-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Bryant Ranch Prepack | 63629-2437-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | Rising Pharma Holdings, Inc. | 64980-0706-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet · Oral | Rising Pharma Holdings, Inc. | 64980-0707-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet · Oral | Rising Pharma Holdings, Inc. | 64980-0708-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | Amneal Pharmaceuticals LLC | 65162-0511-03 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet · Oral | Amneal Pharmaceuticals LLC | 65162-0514-03 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet · Oral | Amneal Pharmaceuticals LLC | 65162-0515-03 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Aphena Pharma Solutions - Tennessee, LLC | 67544-0310-30 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Film Coated · Oral | Zydus Pharmaceuticals (USA) Inc. | 68382-0660-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Zydus Pharmaceuticals (USA) Inc. | 68382-0661-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Zydus Pharmaceuticals (USA) Inc. | 68382-0662-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Coated · Oral | Oxford Pharmaceuticals, LLC | 69584-0852-09 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Coated · Oral | Oxford Pharmaceuticals, LLC | 69584-0853-09 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Coated · Oral | Oxford Pharmaceuticals, LLC | 69584-0854-09 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Coated · Oral | REMEDYREPACK INC. | 70518-3625-00 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Coated · Oral | REMEDYREPACK INC. | 70518-3655-02 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Coated · Oral | REMEDYREPACK INC. | 70518-3721-00 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Proficient Rx LP | 71205-0147-30 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Proficient Rx LP | 71205-0148-30 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | Proficient Rx LP | 71205-0772-30 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | Aphena Pharma Solutions - Tennessee, LLC | 71610-0102-60 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Film Coated · Oral | Aphena Pharma Solutions - Tennessee, LLC | 71610-0287-30 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Film Coated · Oral | Aphena Pharma Solutions - Tennessee, LLC | 71610-0288-30 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Coated · Oral | Direct_Rx | 72189-0496-30 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Coated · Oral | Direct_Rx | 72189-0497-30 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet · Oral | NorthStar Rx LLC | 72603-0134-01 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet · Oral | NorthStar Rx LLC | 72603-0135-01 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet · Oral | NorthStar Rx LLC | 72603-0136-01 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Coated · Oral | PD-Rx Pharmaceuticals, Inc. | 72789-0290-30 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Coated · Oral | PD-Rx Pharmaceuticals, Inc. | 72789-0291-30 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Coated · Oral | PD-Rx Pharmaceuticals, Inc. | 72789-0292-30 |
| Spironolactone | SPIRONOLACTONE 100 mg/1 | Tablet, Coated · Oral | Proficient Rx LP | 82804-0205-30 |
| Spironolactone | SPIRONOLACTONE 25 mg/1 | Tablet, Coated · Oral | Proficient Rx LP | 82804-0255-30 |
| Spironolactone | SPIRONOLACTONE 50 mg/1 | Tablet, Coated · Oral | Proficient Rx LP | 82804-0285-30 |
Other dosage forms of spironolactone
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 30 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Spironolactone 25 mg | Mylan | 100 tablets | $0.043 | AB | Availability likely |
| spironolactone 25 mg | Major | 100 tablets | $0.043 | AB | Availability likely |
| spironolactone 25 mg | Camber | 100 tablets | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | Mylan | 1 tablet | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | Sun | 100 tablets | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | Amneal | 100 tablets | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | Aurobindo | 100 tablets | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | American | 100 tablets | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | Rising | 100 tablets | $0.043 | AB | Availability likely |
| spironolactone 25 mg | Zydus | 100 tablets | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | Oxford | 100 tablets | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | NorthStar | 100 tablets | $0.043 | AB | Availability likely |
| Spironolactone 25 mg | Accord | 100 tablets | $0.045 | AB | Availability likely |
| Spironolactone 25 mg | Jubilant | 100 tablets | $0.052 | AB | FDA listed |
| Spironolactone 100 mg | Mylan | 100 tablets | $0.168 | AB | Availability likely |
| spironolactone 100 mg | Camber | 100 tablets | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | Mylan | 1 tablet | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | Sun | 100 tablets | $0.168 | AB | Discontinued |
| Spironolactone 100 mg | Amneal | 100 tablets | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | Aurobindo | 100 tablets | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | Jubilant | 100 tablets | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | American | 100 tablets | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | Rising | 100 tablets | $0.168 | AB | Availability likely |
| spironolactone 100 mg | Zydus | 100 tablets | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | Oxford | 100 tablets | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | NorthStar | 100 tablets | $0.168 | AB | Availability likely |
| Spironolactone 100 mg | Accord | 100 tablets | $0.178 | AB | Availability likely |
| Aldactone 100 mg | Pfizer | 100 tablets | — | AB | FDA listed |
| Spironolactone 100 mg | PD-Rx | 30 tablets | — | AB | FDA listed |
| Spironolactone 100 mg | Safecor | 1 tablet | — | AB | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Aldactone — that fall in the same broad treatment class (potassium sparing diuretics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Codes & classification for pharmacists and billers
Where does this data come from?
Other cardiovascular shortages
Aldactone shortage FAQs
Is Aldactone still in shortage?
Which strengths of Aldactone are affected?
Which Aldactone products are affected?
When will Aldactone be available again?
Can I still get Aldactone or its generic somewhere?
Is the brand or the generic affected?
What should I do if I take Aldactone?
Still have a question about the Aldactone shortage?
Ask a pharmacist about this shortage →View Spironolactone Tablet on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (companies listing the same ingredient & form — the "other companies" the rating counts); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.