Ifosfamide Injection shortage
Ifosfamide Injection is currently listed in shortage by the FDA. The FDA lists 8 affected products. The reported reason: Demand increase for the drug; Requirements related to complying with good manufacturing practices. This page was last refreshed from FDA data on Oct 3, 2026.
Ifosfamide injection is in short supply, with the 50 mg/1 mL concentration currently unavailable from any source. The 1 g/20 mL and 3 g/60 mL concentrations still have available sources, and a lyophilized powder form is listed by Fresenius Kabi, which has not reported a shortage.
Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers (see options) and your prescriber about a long-term plan.
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Ifosfamide Injection. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Sep 18, 2026Currently in shortage8 of 8 products affected.
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Sep 17, 2026FDA refreshed this shortage record4 products updated.
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Sep 15, 2026FDA refreshed this shortage record1 product updated.
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Sep 8, 2026FDA refreshed this shortage record1 product updated.
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Jun 12, 2026First reported to the FDA8 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Baxter Healthcare 📞 888-229-0001 4 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Ifosfamide, Injection, 3 g/60 mL (NDC 10019-926-02) | — | Available | — | — |
| Current | IFEX, Injection, 1 g/20 mL (NDC 0338-3991-01) | — | Unavailable | Estimated recovery: September 2026 | Requirements related to complying with good manufacturing pr... |
| Current | IFEX, Injection, 3 g/60 mL (NDC 0338-3993-01) | — | Unavailable | Estimated recovery: October 2026 | Requirements related to complying with good manufacturing pr... |
| Current | Ifosfamide, Injection, 1 g/20 mL (NDC 10019-925-01) | — | Available | — | — |
Manufacturer: Fresenius Kabi USA, LLC 📞 888-386-1300 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Ifosfamide, Injection, 1 g/1 (NDC 63323-142-10) | — | Limited Availability | Check wholesalers for inventory | Demand increase for the drug |
Manufacturer: Hikma Pharmaceuticals USA, Inc. 📞 800-631-2174 2 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Ifosfamide, Injection, 50 mg/1 mL (NDC 0143-9530-01) | — | Unavailable | Additional lots will be available in the September 2026 timeframe. Product will be made available as it is released. | Demand increase for the drug |
| Current | Ifosfamide, Injection, 50 mg/1 mL (NDC 0143-9531-01) | — | Unavailable | Additional lots will be available in the September 2026 timeframe. Product will be made available as it is released. | Demand increase for the drug |
Manufacturer: SteriMax, Inc. 📞 877-373-4657 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Ifosfamide, Injection, 1 g/1 (NDC 21586-211-02) | — | Available | To place an order, please contact GlobalRX at [email protected] or (919) 245-8418 | — |
These rows are manufacturer reports to the FDA for Ifosfamide Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Ifosfamide Injection? options further down this page.
Why is Ifosfamide Injection in shortage?
There are two things driving the ifosfamide shortage right now. First, more people need this medication than usual, which has stretched supplies thin — particularly affecting Hikma's 50 mg/1 mL vials, with additional lots expected around September 2026. Second, Baxter is having issues meeting certain manufacturing quality standards (what the FDA calls "good manufacturing practices"), which has made their branded IFEX products temporarily unavailable — specifically the 1 g/20 mL vials (estimated back September 2026) and the 3 g/60 mL vials (estimated back October 2026). Fresenius Kabi's 1 g/1 vial is currently in limited supply, also due to higher-than-usual demand.
It's worth noting that not every product from every company is affected. Baxter's generic 1 g/20 mL and 3 g/60 mL ifosfamide vials are still listed as available, and SteriMax's 1 g/1 vial is also currently available through GlobalRX.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Ifosfamide Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Ifosfamide Injection?
Ifosfamide Injection is currently on the FDA shortage list. This is a chemotherapy medicine that is usually given in a clinic or hospital setting, so your care team manages the supply closely.
Here is how the strengths look right now. The 1 g/20 mL, 3 g/60 mL, and 1 g/1 strengths still have an available source from one or more manufacturers. The 50 mg/1 mL strength has no available source at this time; the maker reports additional lots are expected in the September 2026 timeframe, and product will be released as it becomes available.
The reasons given are increased demand for the drug and steps tied to meeting good manufacturing practices. Several manufacturers are still supplying ifosfamide, which is reassuring. Some estimated recovery notes point to September–October 2026 for the affected lots.
What you can do:
- Do not stop, skip, or change your treatment on your own — your oncology team coordinates this medicine.
- If you take a strength that still has supply, ask your pharmacy or clinic to order it; they can check wholesalers and other manufacturers.
- If your strength is hard to find, ask your prescriber or pharmacist about options, such as using a different available strength.
Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls.
This is national, manufacturer-reported data and may not match local stock.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Ifosfamide Injection?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Ifosfamide Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Ifosfamide | IFOSFAMIDE 1 g/1 | Injection, Powder, Lyophilized, For Solution · Intravenous | Fresenius Kabi USA, LLC | 63323-0142-12 |
Therapeutic equivalents & pricing 7 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Ifex 3 g/60mL | Baxter | 1 vial | — | AP | FDA listed |
| Ifosfamide 3 g/60mL | Baxter | 1 vial | — | AP | FDA listed |
| Ifosfamide 3 g/60mL | Baxter | 1 vial | — | AP | FDA listed |
| Ifex 1 g/20mL | Baxter | 1 vial | — | AP | FDA listed |
| Ifosfamide 1 g/20mL | Baxter | 1 vial | — | AP | FDA listed |
| Ifosfamide 1 g/20mL | Baxter | 1 vial | — | AP | FDA listed |
| Ifosfamide 1 g | Fresenius | 1 vial | — | AP | Discontinued |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Ifosfamide Injection — that fall in the same broad treatment class (antineoplastic - alkylating agents) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Ifosfamide Injection shortage FAQs
Is Ifosfamide Injection in shortage?
Why is Ifosfamide Injection in shortage?
Which products are affected?
When will Ifosfamide Injection be available again?
Can I still get Ifosfamide somewhere?
What should I do if I take Ifosfamide Injection?
Still have a question about the Ifosfamide Injection shortage?
Ask a pharmacist about this shortage →View Ifosfamide Injection on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.