Conivaptan Hydrochloride Injection shortage
Conivaptan Hydrochloride Injection is currently listed in shortage by the FDA. The FDA lists 1 affected product. The reported reason: Delay in shipping of the drug. This page was last refreshed from FDA data on Sep 21, 2026.
Conivaptan hydrochloride injection (20 mg/100 mL) is currently unavailable due to a shipping delay reported by Cumberland Pharmaceuticals, with no estimated recovery date. No other manufacturers of this medicine are on record, so there is no available source right now.
Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers and your prescriber about a long-term plan.
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Conivaptan Hydrochloride Injection. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Sep 16, 2026Currently in shortage1 of 1 product affected.
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Mar 14, 2022First reported to the FDA1 product first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Cumberland Pharmaceuticals Inc. 📞 800-706-5575 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Vaprisol Dextrose In Plastic Container, Injection, 20 mg/100 mL (NDC 66220-160-10) | — | Unavailable | Estimated recovery: TBD | Delay in shipping of the drug |
These rows are manufacturer reports to the FDA for Conivaptan Hydrochloride Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Conivaptan Hydrochloride Injection? options further down this page.
Why is Conivaptan Hydrochloride Injection in shortage?
Right now, Cumberland Pharmaceuticals is having trouble getting their version of conivaptan hydrochloride (Vaprisol) shipped out. Specifically, the 20 mg/100 mL bag in the plastic container (the 10-pack) is currently unavailable because of a shipping delay — meaning the product may be ready, but it's not making it through the distribution process on time. Unfortunately, Cumberland hasn't given a firm date for when this will be resolved, so the recovery timeline is listed as "to be determined."
Because this is a shipping issue rather than a manufacturing stoppage, the situation could change, but there's no estimated return date to share just yet.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Conivaptan Hydrochloride Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Conivaptan Hydrochloride Injection?
Conivaptan Hydrochloride Injection is currently on the FDA drug-shortage list. I want to walk you through what this means so you know what to expect and what steps make sense.
The one strength on this record, 20 mg/100 mL, has no available source reported right now. This is the only strength listed, and there are no other strengths showing supply at this time. The reported reason is a delay in shipping of the drug, and only one manufacturer is on this record. An estimated recovery date has not yet been set (listed as TBD), and this shortage has lasted more than a year.
Even so, this report reflects only the manufacturer that filed it, so it does not mean every supplier is out. Here is what you can do:
- Do not stop, skip, or change your dose on your own.
- Ask your pharmacy to check wholesalers and other manufacturers, since this is a hospital-administered injection and local availability can differ from national data.
- If your dose cannot be found, ask your prescriber or pharmacist about options they can choose for you.
- Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle these calls.
This is general, manufacturer-reported information and may not match your local stock, so please lean on your care team for guidance.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Other drugs in the same treatment class
These are different medicines — not other versions of Conivaptan Hydrochloride Injection — that fall in the same broad treatment class (arginine vasopressin (avp) receptor antagonists) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Other cardiovascular shortages
Conivaptan Hydrochloride Injection shortage FAQs
Is Conivaptan Hydrochloride Injection in shortage?
Why is Conivaptan Hydrochloride Injection in shortage?
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When will Conivaptan Hydrochloride Injection be available again?
What should I do if I take Conivaptan Hydrochloride Injection?
Still have a question about the Conivaptan Hydrochloride Injection shortage?
Ask a pharmacist about this shortage →View Conivaptan Hydrochloride Injection on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.