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Bumetanide Injection shortage

Bumetanide Injection is currently listed in shortage by the FDA. The FDA lists 12 affected products. The reported reason: Demand increase for the drug. This page was last refreshed from FDA data on Sep 21, 2026.

Current ⚠ Supply risk: Low Cardiovascular 12 products 5 manufacturers 3,204 days · 8.8 yr First posted Dec 13, 2017 Updated Sep 16, 2026
Here’s the bottom line

Bumetanide injection has been in short supply for over a year due to higher demand. All strengths still have at least some supply available, and other manufacturers not reporting a shortage also list this medicine.

Don’t stop or change your therapy on your own — ask your pharmacist about other manufacturers (see options) and your prescriber about a long-term plan.

Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →
12
Affected NDCs
5
Reporting manufacturers
5/5
Reporting mfrs supplying
6/6
Affected strengths / sizes supplied
8%
NDCs unavailable
3,204
Days in shortage
477
Medicaid Rx (2026)
Source: FDA Drug Shortages Database API (openFDA). Last refreshed Sep 21, 2026 · today

What’s in shortage — at a glance

These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Bumetanide Injection. Other makers that haven’t reported a problem are shown in the green card below.

Availability of affected NDCs
From the FDA shortage report
12 NDCs
Available 11 Unavailable 1
Affected strengths / sizes still supplied
Among manufacturers reporting this shortage
6/6 strengths / sizes
Sourceable 6
FDA-reporting manufacturers with supply
Among manufacturers reporting this shortage
5/5 makers
With supply 5
✓ Other manufacturers not reporting a shortage
Still-marketed Bumetanide Injection from companies that have not filed an FDA shortage — these are not counted in the figures above. Stock can still vary by pharmacy.
Hikma Pharmaceuticals USA Inc. Camber Pharmaceuticals, Inc. GLENMARK PHARMACEUTICALS INC., USA Lupin Pharmaceuticals, Inc. Bryant Ranch Prepack Civica, Inc.
Plus 6 alternative dosage forms of Bumetanide.
See all other options & details →
Shortage timeline
  1. Sep 16, 2026
    Currently in shortage
    12 of 12 products affected.
  2. Sep 15, 2026
    FDA refreshed this shortage record
    2 products updated.
  3. Sep 3, 2026
    FDA refreshed this shortage record
    2 products updated.
  4. Aug 18, 2026
    FDA refreshed this shortage record
    2 products updated.
  5. Jan 31, 2018
    More presentations reported
    6 more products added to the shortage.
  6. Dec 13, 2017
    First reported to the FDA
    6 products first listed.

Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.

What exactly is on backorder — by manufacturer

Manufacturer: Fresenius Kabi USA, LLC 📞 888-386-1300 2 NDCS click to expand
Status NDC / product Strength / size Availability Related information Reason
Current Bumetanide, Injection, .25 mg/1 mL (NDC 65219-572-10) NDC 65219-0572-10 Available Check wholesalers for inventory
Current Bumetanide, Injection, .25 mg/1 mL (NDC 65219-570-04) NDC 65219-0570-04 Available Check wholesalers for inventory
Manufacturer: Hikma Pharmaceuticals USA, Inc. 📞 800-631-2174 2 NDCS click to expand
Status NDC / product Strength / size Availability Related information Reason
Current Bumetanide, Injection, .25 mg/1 mL (NDC 0641-6008-10) NDC 00641-6008-10 Available Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Current Bumetanide, Injection, .25 mg/1 mL (NDC 0641-6007-10) NDC 00641-6007-10 Unavailable Additional lots will be available in the September 2026 timeframe. Product will be made available as it is released. Demand increase for the drug
Manufacturer: MSN Laboratories Private Limited 📞 855-668-2369; [email protected] 4 NDCS click to expand
Status NDC / product Strength / size Availability Related information Reason
Current Bumetanide, Injection, 0.25 mg/1 mL (NDC 72205-102-07) NDC 72205-0102-07 Available
Current Bumetanide, Injection, 0.25 mg/mL, 4mL (NDC 72205-101-01) NDC 72205-0101-01 Available
Current Bumetanide, Injection, 0.25 mg/1 mL (NDC 72205-101-07) NDC 72205-0101-07 Available
Current Bumetanide, Injection, 0.25 mg/mL, 10 mL (NDC 72205-102-01) NDC 72205-0102-01 Available
Manufacturer: Mullan Pharmaceutical Inc. 📞 800-673-9839 2 NDCS click to expand
Status NDC / product Strength / size Availability Related information Reason
Current Bumetanide, Injection, 2.5 mg/10 mL (0.25 mg/mL) (NDC 83301-0081-2) NDC 83301-0081-02 Available
Current Bumetanide, Injection, 1 mg/4 mL (0.25 mg/mL) (NDC 83301-0080-2) NDC 83301-0080-02 Available
Manufacturer: Sagent Pharmaceuticals 📞 866-625-1618 2 NDCS click to expand
Status NDC / product Strength / size Availability Related information Reason
Current Bumetanide, Injection, .25 mg/1 mL (NDC 25021-321-10) NDC 25021-0321-10 Available
Current Bumetanide, Injection, .25 mg/1 mL (NDC 25021-321-04) NDC 25021-0321-04 Available

These rows are manufacturer reports to the FDA for Bumetanide Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Bumetanide Injection? options further down this page.

Why is Bumetanide Injection in shortage?

The main reason Bumetanide Injection is on the FDA shortage list is that more people need it than the usual supply can keep up with — what the FDA calls a "demand increase." For Hikma Pharmaceuticals specifically, one of their 0.25 mg/1 mL presentations is currently unavailable because of this higher-than-normal demand, and they expect additional lots of that product to be ready around September 2026. Their other 0.25 mg/1 mL presentation is still available, with more manufacturing scheduled to help meet demand.

It's worth knowing that this shortage report covers multiple manufacturers, and several of them — including MSN Laboratories, Fresenius Kabi, Mullan Pharmaceutical, and Sagent Pharmaceuticals — are reporting their Bumetanide Injection products as currently available. Fresenius Kabi notes that you may need to check with wholesalers to find their inventory.

FDA reason code(s): Demand increase for the drug

Based on the manufacturer-reported reason(s) and notes on file with the FDA for Bumetanide Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.

What should I do if I take Bumetanide Injection?

Bumetanide Injection is currently on the FDA shortage list, but supply overall remains strong, so this should have little effect on your care.

Here is the part that matters most for finding what you take: every strength on this record still has an available source. That includes the 0.25 mg/mL vials in the 4 mL, 10 mL, and 2.5 mg/10 mL sizes, as well as the 1 mg/4 mL size. No strength is currently listed with no source at all. One manufacturer marked a single lot as temporarily unavailable, with additional lots expected around September 2026, but four other makers still report the same medicine as available.

The reported reason is simply higher demand. All five manufacturers on this record are still supplying, and more lots are scheduled to be made.

What you can do:

  • Do not stop, skip, or change your dose on your own.
  • Ask your pharmacy to order your strength — they can check wholesalers and other manufacturers, since supply exists.
  • If your usual product is briefly out, this same medicine is available from other makers your pharmacy may be able to source, though it may not be in local stock.
  • If a specific product cannot be found, ask your prescriber or pharmacist about options.

Manufacturer contact numbers are listed on this page for reference; pharmacies usually handle those calls. This reflects national data and may not match your local pharmacy's stock.

See “Where else can I get Bumetanide Injection?” below ↓ The same medicine from manufacturers not reporting a shortage, alternative dosage forms, and therapeutic equivalents with pricing.
If you are a patient:
  • Don’t stop or change the medication on your own — talk to your prescriber first.
  • If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
  • Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
  • Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Keep reading
Our full Bumetanide guide

Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.

Read the Bumetanide guide →

Where else can I get Bumetanide Injection?

FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Bumetanide Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.

Same medicine, other manufacturers (not reported short)

Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:

ProductStrengthForm / routeManufacturerNDC
Bumetanide BUMETANIDE .25 mg/mL Injection · Intramuscular, Intravenous Hikma Pharmaceuticals USA Inc. 00641-6284-10
Bumetanide BUMETANIDE .25 mg/mL Injection · Intramuscular, Intravenous Camber Pharmaceuticals, Inc. 31722-0368-32
Bumetanide BUMETANIDE .25 mg/mL Injection · Intramuscular, Intravenous GLENMARK PHARMACEUTICALS INC., USA 68462-0469-54
Bumetanide BUMETANIDE .25 mg/mL Injection · Intramuscular, Intravenous Lupin Pharmaceuticals, Inc. 70748-0323-10
Bumetanide BUMETANIDE .25 mg/mL Injection · Intramuscular, Intravenous Bryant Ranch Prepack 72162-2632-02
Bumetanide BUMETANIDE .25 mg/mL Injection · Intramuscular, Intravenous Civica, Inc. 72572-0040-10

Alternative dosage forms of Bumetanide

A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:

Therapeutic equivalents & pricing 30 productsclick to expand

Orange Book–rated equivalents of the affected strengths / sizes, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.

ProductManufacturerPackageNADAC $/unitAB ratingAvailability
Bumetanide .25 mg/mLNDC 00641-6007-10 Hikma 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 00641-6285-10 Hikma 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 25021-0321-04 Sagent 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 31722-0369-32 Camber 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 65219-0572-10 Fresenius 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 67184-0594-02 Qilu 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 68083-0497-10 Gland 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 68462-0470-54 GLENMARK 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 70748-0323-10 Lupin 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 72162-2632-02 Bryant 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 72205-0102-07 Novadoz 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 72572-0041-10 Civica, 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 83301-0081-02 Mullan 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 65219-0570-04 Fresenius 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 68083-0496-10 Gland 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 72205-0101-07 Novadoz 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 72572-0040-10 Civica, 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 00641-6008-10 Hikma 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 00641-6284-10 Hikma 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 83854-0007-10 Anthea 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 31722-0368-32 Camber 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 67184-0593-02 Qilu 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 68462-0469-54 GLENMARK 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 51662-1449-01 HF 4 ml AP FDA listed
Bumetanide .25 mg/mLNDC 72162-2633-02 Bryant 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 83301-0080-02 Mullan 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 55154-1527-05 Cardinal 5 vials AP FDA listed
Bumetanide .25 mg/mLNDC 55154-5131-05 Cardinal 5 vials AP FDA listed
Bumetanide .25 mg/mLNDC 83854-0035-10 Anthea 10 vials AP FDA listed
Bumetanide .25 mg/mLNDC 72572-0211-10 Civica, 10 vials AP FDA listed

Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.

Other drugs in the same treatment class

These are different medicines — not other versions of Bumetanide Injection — that fall in the same broad treatment class (loop diuretics) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.

Identity & classification

GCN Seq No 008220
GCN 34810
HICL code 003664
Ingredient (HICL) Bumetanide
HIC1 code R
Therapeutic class — broad (HIC1) Kidney/Urinary Tract
HIC2 code R1
Therapeutic class — intermediate (HIC2) Affect Primarily Kidneys/Urinary Tract
HIC3 code R1M
Therapeutic class — specific (HIC3) Loop Diuretics
AHFS code 24:36.08.00
AHFS class Loop Diuretics (24:36)
FDB label name BUMETANIDE 2.5 MG/10 ML VIAL
FDB brand name Bumetanide
Legend status F — Federal legend — prescription drug or device
GPI-1437200010002005
Where does this data come from?
Identity codes come from First Databank (FDB) (HICL ingredient, HIC1–3 therapeutic-class hierarchy, GCN, AHFS class, legend status) and Medi-Span GPI, mapped from a representative affected NDC. Licensed reference data — for identification only.

Other cardiovascular shortages

Bumetanide Injection shortage FAQs

Is Bumetanide Injection in shortage?
Yes — the FDA currently lists Bumetanide Injection in shortage (status: “Current”, first reported Dec 13, 2017). 12 of 12 products are affected. This is national, manufacturer-reported data, so your pharmacy may still have stock.
Why is Bumetanide Injection in shortage?
The manufacturer-reported reason on file with the FDA: Demand increase for the drug. Additional lots will be available in the September 2026 timeframe. Product will be made available as it is released.
Which products are affected?
Bumetanide, Injection, .25 mg/1 mL (NDC 65219-572-10) (NDC 65219-0572-10); Bumetanide, Injection, .25 mg/1 mL (NDC 65219-570-04) (NDC 65219-0570-04); Bumetanide, Injection, .25 mg/1 mL (NDC 0641-6008-10) (NDC 00641-6008-10). The full per-NDC list (availability, manufacturer and status) is in the table above — each NDC links to its own page.
When will Bumetanide Injection be available again?
The manufacturer reports: Additional lots will be available in the September 2026 timeframe. Product will be made available as it is released. The FDA does not publish a single guaranteed restock date — confirm with your pharmacy.
Can I still get Bumetanide somewhere?
Other manufacturers (Hikma Pharmaceuticals USA Inc., Camber Pharmaceuticals, Inc., GLENMARK PHARMACEUTICALS INC., USA and others) still market it and have not reported a shortage. 6 alternative dosage forms of Bumetanide are also listed. See “Where else can I get Bumetanide Injection?” above — stock still varies by pharmacy.
What should I do if I take Bumetanide Injection?
Don’t stop or change it on your own. Ask your pharmacist whether they can order it from another manufacturer or a different strength/package size, and ask your prescriber about a long-term plan before your supply runs out.

Still have a question about the Bumetanide Injection shortage?

Ask a pharmacist about this shortage →
How to read the Supply-Risk rating
Low (1–2)Multiple manufacturers still supplying and most strengths or pack sizes sourceable.
Medium (3)Some constraint — fewer suppliers or a notable share of NDCs unavailable.
High (4–5)Down to a single source, most strengths or pack sizes unsourceable, or a long-running outage.
Where does this data come from?
Shortage records come from the FDA Drug Shortages Database API via openFDA (/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.
Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD.
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