Atropine Sulfate Injection shortage
Atropine Sulfate Injection is currently listed in shortage by the FDA. The FDA lists 19 affected products. The reported reason: Requirements related to complying with good manufacturing practices; Discontinuation of the manufacture of the drug; Other. This page was last refreshed from FDA data on Sep 24, 2026.
Some strengths of atropine sulfate injection are currently hard to get, particularly the 0.05 mg/mL vials and certain LifeShield® prefilled glass syringes. Several other strengths remain listed as available from multiple manufacturers, including Hikma, Amneal, and others not reporting a shortage.
Don’t stop or change your therapy on your own — talk with your prescriber about the plan that fits you, and ask your pharmacist what’s actually available (see options).
Do you take this drug? See the ‘What to do’ recommendation from Dr. Brian Staiger, PharmD →What’s in shortage — at a glance
These figures count only the manufacturers that reported this shortage to the FDA — not every company that makes Atropine Sulfate Injection. Other makers that haven’t reported a problem are shown in the green card below.
Shortage timeline
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Sep 22, 2026Currently in shortage19 of 19 products affected.
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Sep 18, 2026FDA refreshed this shortage record1 product updated.
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Sep 16, 2026FDA refreshed this shortage record1 product updated.
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Sep 15, 2026FDA refreshed this shortage record6 products updated.
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Sep 11, 2026FDA refreshed this shortage record3 products updated.
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Sep 1, 2026FDA refreshed this shortage record4 products updated.
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Aug 24, 2026FDA refreshed this shortage record1 product updated.
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Nov 7, 2025FDA refreshed this shortage record2 products updated.
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Nov 7, 2025More presentations reported2 more products added to the shortage.
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Dec 20, 2023More presentations reported1 more product added to the shortage.
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Jan 1, 2020More presentations reported4 more products added to the shortage.
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Jan 1, 2012First reported to the FDA12 products first listed.
Built from FDA posting and update dates. The end date FDA publishes is the posting/update date, not a true resolution date, so durations are approximate.
What exactly is on backorder — by manufacturer
Manufacturer: Accord Healthcare Inc. 📞 866-941-7875, option 2 6 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Atropine Sulfate, Injection, 0.1 mg/1 mL (NDC 16729-484-45) | — | Available | — | — |
| Current | Atropine Sulfate, Injection, .05 mg/1 mL (NDC 16729-483-03) | — | Unavailable | Discontinuation of the manufacture of the drug | Discontinuation of the manufacture of the drug |
| Current | Atropine Sulfate, Injection, .1 mg/1 mL (NDC 16729-484-90) | — | Unavailable | Discontinuation of the manufacture of the drug | Discontinuation of the manufacture of the drug |
| Current | Atropine Sulfate, Injection, .4 mg/1 mL (NDC 16729-525-08) | — | Unavailable | Estimated recovery: mid-September 2026 | Requirements related to complying with good manufacturing pr... |
| Current | Atropine Sulfate, Injection, .4 mg/1 mL (NDC 16729-512-43) | — | Unavailable | Estimated recovery: TBD | Requirements related to complying with good manufacturing pr... |
| Current | Atropine Sulfate, Injection, 1 mg/1 mL (NDC 16729-526-08) | — | Unavailable | Estimated recovery: TBD | Requirements related to complying with good manufacturing pr... |
Manufacturer: American Regent, Inc. 📞 800-645-1706 2 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Atropine Sulfate, Injection, .4 mg/1 mL (NDC 0517-1004-25) | — | Available | — | — |
| Current | Atropine Sulfate, Injection, 1 mg/1 mL (NDC 0517-1001-25) | — | Available | — | — |
Manufacturer: Amphastar Pharmaceuticals, Inc. 📞 800-423-4136 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Atropine Sulfate, Injection, .1 mg/1 mL (NDC 76329-3340-1) | — | Available | — | — |
Manufacturer: Fresenius Kabi USA, LLC 📞 888-386-1300 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Atropine Sulfate, Injection, .4 mg/1 mL (NDC 63323-580-20) | — | Available | Check wholesalers for inventory | — |
Manufacturer: Hikma Pharmaceuticals USA, Inc. 📞 800-631-2174 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Atropine Sulfate, Injection, 0.4 mg/1 mL (NDC 0641-6251-10) | — | Available | — | — |
Manufacturer: Hospira, Inc., a Pfizer Company 📞 844-646-4398 4 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Atropine Sulfate, Injection, 0.25 mg/5 mL (0.05 mg/mL) Syringes (NDC 0409-9630-05) | — | Available | — | — |
| Current | Atropine Sulfate, Injection, 1 mg/10 mL (0.1 mg/mL) Syringes (NDC 0409-1630-10) | — | Unavailable | Next Delivery: August 2026; Estimated Recovery: September 2026; Shortage per Manufacturer: Manufacturing Delay | Other |
| To Be Discontinued | Atropine Sulfate, Injection, (Adult) 0.5 mg/5 mL (0.1 mg/mL) LifeShield® ABBOJECT® Glass Syringe (20 G x 1 1/2) (NDC 0409-4910-34)" | — | — | Discontinuation of the manufacture of the drug | — |
| To Be Discontinued | Atropine Sulfate, Injection, (Adult)1 mg/10 mL (0.1 mg/mL) LifeShield® ABBOJECT® Glass Syringe (20 G x 1 1/2) (NDC 0409-4911-34)" | — | — | Discontinuation of the manufacture of the drug | — |
Manufacturer: Medefil, Inc. 📞 630-682-4600 1 NDC click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Atropine Sulfate, Injection, 1 mg/10 mL (0.1 mg/mL) Syringes (NDC 64253-400-91) | — | Available | — | — |
Manufacturer: Somerset Therapeutics, LLC 📞 732-554-1037 3 NDCS click to expand
| Status | NDC / product | Strength | Availability | Related information | Reason |
|---|---|---|---|---|---|
| Current | Atropine Sulfate, Injection, .4 mg/1 mL (NDC 70069-631-25) | — | Available | — | — |
| Current | Atropine Sulfate, Injection, .4 mg/1 mL (NDC 70069-481-10) | — | Available | — | — |
| Current | Atropine Sulfate, Injection, 1 mg/1 mL (NDC 70069-641-25) | — | Available | — | — |
These rows are manufacturer reports to the FDA for Atropine Sulfate Injection — they do not necessarily cover every manufacturer that makes this drug. A company appears here only if it told the FDA it has a supply problem, so other makers may still have stock. That’s the basis for the Where else can I get Atropine Sulfate Injection? options further down this page.
Why is Atropine Sulfate Injection in shortage?
There are a few different things going on with Atropine Sulfate Injection from the manufacturers covered in this report. Accord Healthcare has permanently stopped making two of its strengths — the 0.05 mg/1 mL and 0.1 mg/1 mL vials — meaning those specific products won't be coming back from them. Several of Accord's other strengths (1 mg/1 mL and two versions of 0.4 mg/1 mL) are currently unavailable due to manufacturing compliance issues, with one of the 0.4 mg/1 mL versions expected to recover around mid-September 2026 and the others still listed as "to be determined." Accord's 0.1 mg/1 mL (a different package) is still available from them.
Hospira (a Pfizer company) has permanently stopped making its two LifeShield® ABBOJECT® glass syringe versions — the adult 1 mg/10 mL and 0.5 mg/5 mL glass syringes. Their 1 mg/10 mL plastic syringe is temporarily unavailable due to a manufacturing delay, with the next delivery expected in August 2026 and recovery estimated for September 2026. Their 0.25 mg/5 mL syringe remains available. This report covers only these specific manufacturers and their products.
Based on the manufacturer-reported reason(s) and notes on file with the FDA for Atropine Sulfate Injection, summarized in plain English by HelloPharmacist. A drug can be short for more than one reason, and the FDA updates these as manufacturers report changes.
What should I do if I take Atropine Sulfate Injection?
Atropine Sulfate Injection is currently on the FDA drug-shortage list. This is a medicine that hospitals and clinics often use, and I want to walk you through where supply stands so you can find the strength you take.
Several strengths still have an available source, including 0.1 mg/1 mL, 1 mg/1 mL, 0.4 mg/1 mL, and the 0.25 mg/5 mL syringes. A few others currently have no available source: the 0.05 mg/1 mL vial, and two adult prefilled glass syringes (1 mg/10 mL and 0.5 mg/5 mL). These three are reported as discontinued by the maker that filed this record, so for those the supply problem may be lasting.
The reported reasons include manufacturing-practice requirements, product discontinuation, and other factors. Importantly, all eight manufacturers on this record still report some available supply, and one syringe product lists an estimated recovery around September 2026.
Do not stop, skip, or change your dose on your own. Instead:
- If your strength still has supply, ask your pharmacy to order it — they can check wholesalers and other makers.
- The same medicine may be available from another manufacturer; your pharmacy may be able to source one, though it may not be in local stock.
- If your exact strength is discontinued or cannot be found, ask your prescriber or pharmacist about options.
Manufacturer contact numbers are listed on this page for reference. This reflects national data and may not match your local pharmacy's stock.
- Don’t stop or change the medication on your own — talk to your prescriber first.
- If this is part of an ongoing or essential regimen (for example HIV treatment or prevention, seizure, heart, transplant, diabetes or mental-health medicines), do not skip or ration doses — contact your pharmacist or prescriber right away to arrange continued supply before you run out.
- Ask your pharmacy to check other manufacturers, strengths, package sizes, and nearby stores.
- Ask your prescriber whether a different strength, formulation, or the brand/generic version is appropriate.
Uses, dosing, side effects, prices, and the complete FDA label — written in plain English and pharmacist-reviewed.
Where else can I get Atropine Sulfate Injection?
FDA shortages are manufacturer-reported — a company only shows up on the shortage list if it told the FDA it has a supply problem, so not every maker of Atropine Sulfate Injection is necessarily short. Below we pull together the other still-marketed options that are not reported in shortage: the same medicine from manufacturers that haven’t reported a problem, and alternative dosage forms. These may still be out of stock at your pharmacy, and only your prescriber or pharmacist can decide what’s right for you.
Same medicine, other manufacturers (not reported short)
Same active ingredient, dosage form & route as the shortage (matched on the FDB HICL ingredient code), from makers that have not filed a shortage with the FDA:
| Product | Strength | Form / route | Manufacturer | NDC |
|---|---|---|---|---|
| Atropine Sulfate | ATROPINE SULFATE 1 mg/mL | Injection · Intravenous | Hikma Pharmaceuticals USA Inc. | 00641-6275-25 |
| Atropine Sulfate | ATROPINE SULFATE .05 mg/mL | Injection · Intravenous | Accord Healthcare, Inc., | 16729-0483-31 |
| Atropine Sulfate | ATROPINE SULFATE .1 mg/mL | Injection · Intravenous | Accord Healthcare, Inc., | 16729-0484-03 |
| Atropine Sulfate | ATROPINE SULFATE .1 mg/mL | Injection · Intravenous | A-S Medication Solutions | 50090-5924-00 |
| Atropine Sulfate | ATROPINE SULFATE .1 mg/mL | Injection, Solution · Intravenous | Amneal Pharmaceuticals LLC | 70121-1705-07 |
| Atropine Sulfate | ATROPINE SULFATE .1 mg/mL | Injection · Intravenous | REMEDYREPACK INC. | 70518-3120-00 |
| Atropine Sulfate | ATROPINE SULFATE .4 mg/mL | Injection, Solution · Endotracheal, Intramedullary, Intramuscular, Intravenous, Subcutaneous | REMEDYREPACK INC. | 70518-4188-00 |
| Atropine Sulfate | ATROPINE SULFATE .4 mg/mL | Injection · Endotracheal, Intramedullary, Intramuscular, Intravenous, Subcutaneous | REMEDYREPACK INC. | 70518-4329-00 |
Alternative dosage forms of Atropine Sulfate
A different form of the same drug (for example a solution when capsules are short). A form change is a clinical decision — ask your prescriber:
Therapeutic equivalents & pricing 18 productsclick to expand
Orange Book–rated equivalents of the affected strengths, with the latest NADAC price (a federal retail-acquisition benchmark, not your copay) and an evidence-based availability label. Cheapest first.
| Product | Manufacturer | Package | NADAC $/unit | AB rating | Availability |
|---|---|---|---|---|---|
| Atropine Sulfate .1 mg/mL | Medical | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | Medical | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | Henry | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | A-S | 1 ml | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | HF | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | REMEDYREPACK | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | Accord | 10 syringes | — | AP | FDA listed |
| atropine sulfate .1 mg/mL | Amneal | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | Hospira, | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | ProPharma | 10 ml | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | HF | 1 syringe | — | — | FDA listed |
| Atropine Sulfate .1 mg/mL | HF | 1 syringe | — | — | FDA listed |
| atropine sulfate .1 mg/mL | Amneal | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | International | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .05 mg/mL | Henry | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .05 mg/mL | Hospira, | 1 syringe | — | AP | FDA listed |
| Atropine Sulfate .05 mg/mL | Accord | 10 syringes | — | AP | FDA listed |
| Atropine Sulfate .1 mg/mL | Accord | 10 syringes | — | AP | FDA listed |
Equivalents share the same ingredient, strength, dosage form and route; an AB rating means the FDA considers them substitutable. NADAC is a national retail-pharmacy acquisition benchmark from CMS — not what you pay. Availability is inferred from recent pricing, not a stock check.
Other drugs in the same treatment class
These are different medicines — not other versions of Atropine Sulfate Injection — that fall in the same broad treatment class (belladonna alkaloids) . They are not automatic substitutes: they can differ in how they work, dosing, effectiveness, side effects and what they’re approved to treat. Do not switch on your own. This list is for information only — ask your prescriber or pharmacist whether any of them is appropriate for you.
Identity & classification
Where does this data come from?
Atropine Sulfate Injection shortage FAQs
Is Atropine Sulfate Injection in shortage?
Why is Atropine Sulfate Injection in shortage?
Which products are affected?
When will Atropine Sulfate Injection be available again?
Can I still get Atropine Sulfate somewhere?
What should I do if I take Atropine Sulfate Injection?
Still have a question about the Atropine Sulfate Injection shortage?
Ask a pharmacist about this shortage →View Atropine Sulfate Injection on the FDA drug-shortage database →
Where does this data come from?
/drug/shortages) — drug, manufacturer & contact, NDC/product, status, availability, reason, therapeutic category and posting/update dates. Current / To Be Discontinued = active; Resolved is kept for history. The Supply-Risk rating is assessed per active ingredient and adds the FDA NDC Directory (still-marketed manufacturers by ingredient & form); same-medicine and equivalent products use First Databank classification + CMS NADAC pricing; Medicaid use + most-affected states come from CMS Medicaid State Drug Utilization Data. Reference only — confirm current status with the manufacturer or FDA before acting on it.