Digoxin
Generic name: Pronounced as (di jox' in)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 06/15/2017
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
Why is this medication prescribed?
Digoxin is used to treat heart failure and abnormal heart rhythms (arrhythmias). It helps the heart work better and it helps control your heart rate.
How should this medicine be used?
Digoxin comes as a tablet, capsule, or pediatric elixir (liquid) to take by mouth. Digoxin is usually taken once a day. The pediatric elixir comes with a specially marked dropper for measuring the dose. If you have difficulty, ask your pharmacist to show you how to use it. It is important that you always take the same brand of digoxin. Different brands of digoxin have different amounts of active drug and your dose would need to be changed.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take digoxin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Digoxin helps control your condition but will not cure it. Continue to take digoxin even if you feel well. Do not stop taking digoxin without talking to your doctor.
Other uses for this medicine
Digoxin is also used to treat heart pain (angina) and may be used after a heart attack. Talk to your doctor about the possible risks of using this drug for your condition.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking digoxin,
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tell your doctor and pharmacist if you are allergic to digoxin, digitoxin, or any other drugs.
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tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antacids, antibiotics, calcium, corticosteroids, diuretics ('water pills'), other medications for heart disease, thyroid medications, and vitamins.
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tell your doctor if you have or have ever had thyroid problems, heart arrhythmias, cancer, or kidney disease.
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tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking digoxin, call your doctor.
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talk to your doctor about the risks and benefits of taking this medication if you are 65 years of age or older. Older adults should usually receive low doses of digoxin because higher doses may cause serious side effects.
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if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking digoxin.
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you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
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remember that alcohol can add to the drowsiness caused by this medication.
What special dietary instructions should I follow?
Your doctor may recommend a low-sodium (low-salt) diet and a potassium supplement. Ask your pharmacist or doctor for a list of foods that are low in sodium and high in potassium. Follow all diet directions carefully.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Digoxin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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dizziness or lightheadedness
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drowsiness
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vision changes (blurred or yellow)
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rash
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irregular heartbeat
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Some side effects may be serious. If you experience any of the following symptoms, call your doctor immediately:
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upset stomach
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vomiting
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diarrhea
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loss of appetite
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swelling of the feet or hands
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unusual weight gain
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difficulty breathing
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will need to determine your response to digoxin. You may have electrocardiograms (EKGs) and blood tests periodically, and your dose may need to be adjusted. Your doctor may ask you to check your pulse (heart rate). Ask your pharmacist or doctor to teach you how to take your pulse. If your pulse is faster or slower than it should be, call your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Moxifloxacin | Moxifloxacin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Moxifloxacin. |
Repaglinide | Repaglinide Repaglinide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Atorvastatin | Atorvastatin The serum concentration of Digoxin can be increased when it is combined with Atorvastatin. |
Dolasetron | Dolasetron The risk or severity of QTc prolongation can be increased when Digoxin is combined with Dolasetron. |
Anagrelide | Anagrelide The risk or severity of QTc prolongation can be increased when Digoxin is combined with Anagrelide. |
Calcium Carbonate | Calcium Carbonate Calcium carbonate may increase the arrhythmogenic activities of Digoxin. |
Candesartan | Candesartan The excretion of Digoxin can be decreased when combined with Candesartan. |
Cilostazol | Cilostazol Cilostazol may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Diphenoxylate | Diphenoxylate The serum concentration of Digoxin can be increased when it is combined with Diphenoxylate. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The serum concentration of Digoxin can be increased when it is combined with Erythromycin. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Fenofibrate | Fenofibrate Digoxin may decrease the excretion rate of Fenofibrate which could result in a higher serum level. |
Guanfacine | Guanfacine Guanfacine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Magnesium Hydroxide | Magnesium Hydroxide Magnesium hydroxide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Magnesium Oxide | Magnesium Oxide The serum concentration of Digoxin can be decreased when it is combined with Magnesium oxide. |
Miglitol | Miglitol The serum concentration of Digoxin can be decreased when it is combined with Miglitol. |
Mycophenolate | Mycophenolate Mycophenolic acid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Olsalazine | Olsalazine Olsalazine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Paregoric | Paregoric The serum concentration of Digoxin can be increased when it is combined with Morphine. |
Penbutolol | Penbutolol Acebutolol may increase the arrhythmogenic activities of Digoxin. |
Polyethylene glycol-electrolyte solution (PEG-ES) | Polyethylene glycol-electrolyte solution (PEG-ES) The serum concentration of Digoxin can be decreased when it is combined with Polyethylene glycol. |
Potassium | Potassium Digoxin may decrease the excretion rate of Potassium cation which could result in a higher serum level. |
Prednisone | Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Digoxin. |
Ranitidine | Ranitidine Digoxin may decrease the excretion rate of Ranitidine which could result in a higher serum level. |
Reserpine | Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Digoxin. |
Rizatriptan | Rizatriptan Rizatriptan may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sumatriptan | Sumatriptan Sumatriptan may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tacrolimus | Tacrolimus Tacrolimus may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tizanidine | Tizanidine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Tizanidine. |
Triamcinolone | Triamcinolone The risk or severity of hypokalemia can be increased when Triamcinolone is combined with Digoxin. |
Ampicillin Injection | Ampicillin Injection Ampicillin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Doxycycline Injection | Doxycycline Injection Doxycycline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Famotidine Injection | Famotidine Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Famotidine. |
Fluconazole Injection | Fluconazole Injection Fluconazole may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Foscarnet Injection | Foscarnet Injection Foscarnet may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Hydromorphone Injection | Hydromorphone Injection Hydromorphone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Levofloxacin Injection | Levofloxacin Injection Digoxin may decrease the excretion rate of Levofloxacin which could result in a higher serum level. |
Meperidine Injection | Meperidine Injection Digoxin may decrease the excretion rate of Meperidine which could result in a higher serum level. |
Methylprednisolone Injection | Methylprednisolone Injection The risk or severity of adverse effects can be increased when Methylprednisolone is combined with Digoxin. |
Metoclopramide Injection | Metoclopramide Injection The serum concentration of Digoxin can be decreased when it is combined with Metoclopramide. |
Metronidazole Injection | Metronidazole Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Metronidazole. |
Morphine Injection | Morphine Injection The serum concentration of Digoxin can be increased when it is combined with Morphine. |
Pamidronate Injection | Pamidronate Injection Pamidronic acid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Vancomycin Injection | Vancomycin Injection Vancomycin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Altretamine | Altretamine Amphetamine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefuroxime | Cefuroxime Cefuroxime may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cyclosporine | Cyclosporine The serum concentration of Digoxin can be increased when it is combined with Cyclosporine. |
Ondansetron | Ondansetron The risk or severity of QTc prolongation can be increased when Digoxin is combined with Ondansetron. |
Enoxaparin Injection | Enoxaparin Injection The risk or severity of hyperkalemia can be increased when Digoxin is combined with Enoxaparin. |
Granisetron | Granisetron The risk or severity of QTc prolongation can be increased when Digoxin is combined with Granisetron. |
Olanzapine | Olanzapine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Digoxin. |
Dofetilide | Dofetilide The risk or severity of torsade de pointes can be increased when Dofetilide is combined with Digoxin. |
Eprosartan | Eprosartan The risk or severity of hyperkalemia can be increased when Digoxin is combined with Eprosartan. |
Hydroxychloroquine | Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Hydroxychloroquine. |
Pantoprazole | Pantoprazole Pantoprazole may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sevelamer | Sevelamer Sevelamer can cause a decrease in the absorption of Digoxin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Telmisartan | Telmisartan The serum concentration of Digoxin can be increased when it is combined with Telmisartan. |
Temozolomide | Temozolomide Temozolomide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Zaleplon | Zaleplon Zaleplon may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Desloratadine | Desloratadine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Desloratadine. |
Rivastigmine | Rivastigmine Digoxin may increase the bradycardic activities of Rivastigmine. |
Trimipramine | Trimipramine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Trimipramine. |
Glycopyrrolate | Glycopyrrolate The serum concentration of Digoxin can be increased when it is combined with Glycopyrronium. |
Perindopril | Perindopril Perindopril may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tenofovir | Tenofovir Tenofovir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sirolimus | Sirolimus The serum concentration of Digoxin can be increased when it is combined with Sirolimus. |
Epinephrine Injection | Epinephrine Injection The risk or severity of Cardiac Arrhythmia can be increased when Epinephrine is combined with Digoxin. |
Epirubicin | Epirubicin Epirubicin may decrease the cardiotoxic activities of Digoxin. |
Eplerenone | Eplerenone Eplerenone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Escitalopram | Escitalopram The risk or severity of QTc prolongation can be increased when Digoxin is combined with Escitalopram. |
Zonisamide | Zonisamide Zonisamide may increase the arrhythmogenic activities of Digoxin. |
Aripiprazole | Aripiprazole The risk or severity of QTc prolongation can be increased when Digoxin is combined with Aripiprazole. |
Atomoxetine | Atomoxetine Atomoxetine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ezetimibe | Ezetimibe Ezetimibe may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Teriparatide Injection | Teriparatide Injection The risk or severity of adverse effects can be increased when Teriparatide is combined with Digoxin. |
Atazanavir | Atazanavir Atazanavir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Almotriptan | Almotriptan Almotriptan may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Mefloquine | Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Digoxin. |
Polyethylene Glycol 3350 | Polyethylene Glycol 3350 The serum concentration of Digoxin can be decreased when it is combined with Polyethylene glycol. |
Rosuvastatin | Rosuvastatin Rosuvastatin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Vardenafil | Vardenafil Vardenafil may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Alfuzosin | Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Digoxin. |
Emtricitabine | Emtricitabine Digoxin may decrease the excretion rate of Emtricitabine which could result in a higher serum level. |
Memantine | Memantine Memantine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tegaserod | Tegaserod The serum concentration of Digoxin can be increased when it is combined with Tegaserod. |
Tadalafil | Tadalafil Tadalafil may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Gemifloxacin | Gemifloxacin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Gemifloxacin. |
Progesterone | Progesterone Progesterone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Apomorphine Injection | Apomorphine Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Apomorphine. |
Protriptyline | Protriptyline The risk or severity of QTc prolongation can be increased when Protriptyline is combined with Digoxin. |
Duloxetine | Duloxetine Digoxin may decrease the excretion rate of Duloxetine which could result in a higher serum level. |
Tinidazole | Tinidazole Tinidazole may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Bosentan | Bosentan Bosentan may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefditoren | Cefditoren Cefdinir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cyanocobalamin Injection | Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Erlotinib | Erlotinib The risk or severity of QTc prolongation can be increased when Digoxin is combined with Erlotinib. |
Eszopiclone | Eszopiclone Eszopiclone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ganciclovir | Ganciclovir Ganciclovir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ribavirin | Ribavirin Ribavirin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Solifenacin | Solifenacin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Solifenacin. |
Valganciclovir | Valganciclovir Valganciclovir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Voriconazole | Voriconazole The risk or severity of QTc prolongation can be increased when Digoxin is combined with Voriconazole. |
Adefovir | Adefovir Adefovir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dextroamphetamine | Dextroamphetamine Amphetamine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Peginterferon Alfa-2a Injection | Peginterferon Alfa-2a Injection Digoxin may decrease the cardiotoxic activities of Peginterferon alfa-2a. |
Exenatide Injection | Exenatide Injection The serum concentration of Digoxin can be decreased when it is combined with Exenatide. |
Ibandronate | Ibandronate The risk or severity of QTc prolongation can be increased when Digoxin is combined with Ibandronate. |
Ramelteon | Ramelteon Ramelteon may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Fentanyl | Fentanyl Digoxin may decrease the excretion rate of Fentanyl which could result in a higher serum level. |
Pregabalin | Pregabalin Pregabalin may increase the arrhythmogenic activities of Digoxin. |
Tipranavir | Tipranavir Tipranavir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Felbamate | Felbamate The risk or severity of QTc prolongation can be increased when Digoxin is combined with Felbamate. |
Rasagiline | Rasagiline Rasagiline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Imatinib | Imatinib Digoxin may decrease the excretion rate of Imatinib which could result in a higher serum level. |
Sitagliptin | Sitagliptin Sitagliptin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Varenicline | Varenicline Varenicline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Bevacizumab Injection | Bevacizumab Injection Digoxin may decrease the cardiotoxic activities of Bevacizumab. |
Albuterol | Albuterol The serum concentration of Digoxin can be decreased when it is combined with Salbutamol. |
Paliperidone | Paliperidone Paliperidone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Bortezomib | Bortezomib The risk or severity of QTc prolongation can be increased when Digoxin is combined with Bortezomib. |
Clofarabine Injection | Clofarabine Injection Clofarabine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lubiprostone | Lubiprostone Lubiprostone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Oxaliplatin Injection | Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Oxaliplatin. |
Posaconazole | Posaconazole The serum concentration of Digoxin can be increased when it is combined with Posaconazole. |
Primaquine | Primaquine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Primaquine. |
Aliskiren | Aliskiren The risk or severity of hyperkalemia can be increased when Digoxin is combined with Aliskiren. |
Bismuth Subsalicylate | Bismuth Subsalicylate The serum concentration of Digoxin can be decreased when it is combined with Bismuth subsalicylate. |
Darunavir | Darunavir The excretion of Digoxin can be decreased when combined with Darunavir. |
Pemetrexed Injection | Pemetrexed Injection Digoxin may decrease the excretion rate of Pemetrexed which could result in a higher serum level. |
Dimenhydrinate | Dimenhydrinate The risk or severity of QTc prolongation can be increased when Digoxin is combined with Dimenhydrinate. |
Vorinostat | Vorinostat The risk or severity of QTc prolongation can be increased when Digoxin is combined with Vorinostat. |
Sorafenib | Sorafenib Sorafenib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sunitinib | Sunitinib The risk or severity of QTc prolongation can be increased when Digoxin is combined with Sunitinib. |
Lapatinib | Lapatinib The bioavailability of Digoxin can be increased when combined with Lapatinib. |
Levocetirizine | Levocetirizine Levocetirizine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pegaptanib Injection | Pegaptanib Injection Pegaptanib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dasatinib | Dasatinib The serum concentration of Digoxin can be increased when it is combined with Dasatinib. |
Mexiletine | Mexiletine Mexiletine may increase the arrhythmogenic activities of Digoxin. |
Azacitidine Injection | Azacitidine Injection Azacitidine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ivermectin | Ivermectin The excretion of Digoxin can be decreased when combined with Ivermectin. |
Temsirolimus | Temsirolimus The serum concentration of Digoxin can be increased when it is combined with Temsirolimus. |
Lenalidomide | Lenalidomide Lenalidomide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Nilotinib | Nilotinib Nilotinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Toremifene | Toremifene Toremifene may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Budesonide | Budesonide The risk or severity of adverse effects can be increased when Budesonide is combined with Digoxin. |
Desmopressin | Desmopressin Desmopressin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Doripenem Injection | Doripenem Injection Doripenem may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Etravirine | Etravirine The serum concentration of Digoxin can be increased when it is combined with Etravirine. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection Digoxin may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. |
Mitoxantrone Injection | Mitoxantrone Injection Digoxin may decrease the cardiotoxic activities of Mitoxantrone. |
Desvenlafaxine | Desvenlafaxine Desvenlafaxine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cevimeline | Cevimeline Cevimeline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Nebivolol | Nebivolol Nebivolol may increase the arrhythmogenic activities of Digoxin. |
Tretinoin | Tretinoin Digoxin may decrease the cardiotoxic activities of Tretinoin. |
Bendamustine Injection | Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Digoxin. |
Flecainide | Flecainide The serum concentration of Digoxin can be increased when it is combined with Flecainide. |
Certolizumab Injection | Certolizumab Injection Certolizumab pegol may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ixabepilone Injection | Ixabepilone Injection The serum concentration of Digoxin can be increased when it is combined with Ixabepilone. |
Irinotecan Injection | Irinotecan Injection The excretion of Digoxin can be decreased when combined with Irinotecan. |
Daptomycin Injection | Daptomycin Injection Daptomycin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Methylnaltrexone Injection | Methylnaltrexone Injection Methylnaltrexone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Silodosin | Silodosin The serum concentration of Digoxin can be increased when it is combined with Silodosin. |
Midazolam | Midazolam Midazolam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dexrazoxane Injection | Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Eltrombopag | Eltrombopag The excretion of Digoxin can be decreased when combined with Eltrombopag. |
Milnacipran | Milnacipran The risk or severity of hypotension can be increased when Milnacipran is combined with Digoxin. |
Plerixafor Injection | Plerixafor Injection Plerixafor may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sodium Phosphate | Sodium Phosphate Sodium phosphate, monobasic may increase the hyperkalemic activities of Digoxin. |
Fesoterodine | Fesoterodine Fesoterodine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Degarelix Injection | Degarelix Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Degarelix. |
Betaxolol | Betaxolol Betaxolol may increase the arrhythmogenic activities of Digoxin. |
Iloperidone | Iloperidone The risk or severity of QTc prolongation can be increased when Digoxin is combined with Iloperidone. |
Prasugrel | Prasugrel Prasugrel may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lacosamide | Lacosamide Digoxin may increase the bradycardic activities of Lacosamide. |
Everolimus | Everolimus The serum concentration of Digoxin can be increased when it is combined with Everolimus. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The serum concentration of Digoxin can be increased when it is combined with Tolvaptan. |
Dronedarone | Dronedarone Digoxin may increase the atrioventricular blocking (AV block) activities of Dronedarone. |
Pralatrexate Injection | Pralatrexate Injection Pralatrexate may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Palonosetron Injection | Palonosetron Injection Palonosetron may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Saxagliptin | Saxagliptin Saxagliptin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Telavancin Injection | Telavancin Injection Telavancin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Romidepsin Injection | Romidepsin Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Romidepsin. |
Topotecan | Topotecan Topotecan may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pazopanib | Pazopanib The serum concentration of Digoxin can be increased when it is combined with Pazopanib. |
Asenapine | Asenapine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Asenapine. |
Pitavastatin | Pitavastatin Pitavastatin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dalfampridine | Dalfampridine Dalfampridine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Fingolimod | Fingolimod Digoxin may increase the bradycardic activities of Fingolimod. |
Eribulin Injection | Eribulin Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Eribulin. |
Cabazitaxel Injection | Cabazitaxel Injection The serum concentration of Digoxin can be increased when it is combined with Cabazitaxel. |
Ceftaroline Injection | Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lurasidone | Lurasidone The risk or severity of QTc prolongation can be increased when Digoxin is combined with Lurasidone. |
Acetaminophen Injection | Acetaminophen Injection Acetaminophen may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Vilazodone | Vilazodone The serum concentration of Digoxin can be increased when it is combined with Vilazodone. |
Ipilimumab Injection | Ipilimumab Injection Ipilimumab may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Terbutaline Injection | Terbutaline Injection Terbutaline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Azilsartan | Azilsartan The risk or severity of hyperkalemia can be increased when Digoxin is combined with Azilsartan medoxomil. |
Busulfan Injection | Busulfan Injection Digoxin may decrease the cardiotoxic activities of Busulfan. |
Roflumilast | Roflumilast Roflumilast may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Linagliptin | Linagliptin Linagliptin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Rilpivirine | Rilpivirine The risk or severity of QTc prolongation can be increased when Rilpivirine is combined with Digoxin. |
Telaprevir | Telaprevir Glecaprevir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Potassium Iodide | Potassium Iodide The serum concentration of Digoxin can be increased when it is combined with Potassium Iodide. |
Cyclophosphamide Injection | Cyclophosphamide Injection Digoxin may decrease the cardiotoxic activities of Cyclophosphamide. |
Triptorelin Injection | Triptorelin Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Triptorelin. |
Rivaroxaban | Rivaroxaban Rivaroxaban may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ticagrelor | Ticagrelor The serum concentration of Digoxin can be increased when it is combined with Ticagrelor. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Digoxin. |
Ruxolitinib | Ruxolitinib Ruxolitinib may increase the bradycardic activities of Digoxin. |
Vandetanib | Vandetanib Vandetanib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Clobazam | Clobazam Clobazam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Vemurafenib | Vemurafenib The serum concentration of Digoxin can be increased when it is combined with Vemurafenib. |
Ivacaftor | Ivacaftor Ivacaftor may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Deferiprone | Deferiprone Deferiprone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Axitinib | Axitinib The serum concentration of Axitinib can be increased when it is combined with Digoxin. |
Crizotinib | Crizotinib Crizotinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cabergoline | Cabergoline The serum concentration of Cabergoline can be increased when it is combined with Digoxin. |
Naloxone Injection | Naloxone Injection Naloxone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ambrisentan | Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Digoxin. |
Fondaparinux Injection | Fondaparinux Injection Fondaparinux may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pertuzumab Injection | Pertuzumab Injection Digoxin may decrease the cardiotoxic activities of Pertuzumab. |
Carfilzomib Injection | Carfilzomib Injection Digoxin may decrease the excretion rate of Carfilzomib which could result in a higher serum level. |
Enzalutamide | Enzalutamide Enzalutamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Mirabegron | Mirabegron Mirabegron may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Bosutinib | Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Digoxin. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The risk or severity of adverse effects can be increased when Corticotropin is combined with Digoxin. |
Teriflunomide | Teriflunomide The excretion of Digoxin can be decreased when combined with Teriflunomide. |
Teduglutide Injection | Teduglutide Injection Teduglutide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Bedaquiline | Bedaquiline The risk or severity of QTc prolongation can be increased when Digoxin is combined with Bedaquiline. |
Tofacitinib | Tofacitinib Digoxin may increase the bradycardic activities of Tofacitinib. |
Alogliptin | Alogliptin Alogliptin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ponatinib | Ponatinib Ponatinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pomalidomide | Pomalidomide Pomalidomide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The serum concentration of Digoxin can be increased when it is combined with Trastuzumab emtansine. |
Apixaban | Apixaban The serum concentration of Digoxin can be increased when it is combined with Apixaban. |
Canagliflozin | Canagliflozin The serum concentration of Digoxin can be increased when it is combined with Canagliflozin. |
Methazolamide | Methazolamide Methazolamide may increase the excretion rate of Digoxin which could result in a lower serum level and potentially a reduction in efficacy. |
Dabrafenib | Dabrafenib The serum concentration of Digoxin can be increased when it is combined with Dabrafenib. |
Trametinib | Trametinib Trametinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dolutegravir | Dolutegravir The serum concentration of Digoxin can be increased when it is combined with Dolutegravir. |
Afatinib | Afatinib Afatinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Levomilnacipran | Levomilnacipran The risk or severity of hypotension can be increased when Levomilnacipran is combined with Digoxin. |
Ertapenem Injection | Ertapenem Injection Ertapenem may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tigecycline Injection | Tigecycline Injection Tigecycline can cause an increase in the absorption of Digoxin resulting in an increased serum concentration and potentially a worsening of adverse effects. |
Vortioxetine | Vortioxetine Vortioxetine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lomitapide | Lomitapide Lomitapide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ketorolac Injection | Ketorolac Injection Ketorolac may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Simeprevir | Simeprevir Simeprevir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sofosbuvir | Sofosbuvir Sofosbuvir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dapagliflozin | Dapagliflozin Dapagliflozin may increase the excretion rate of Digoxin which could result in a lower serum level and potentially a reduction in efficacy. |
Apremilast | Apremilast Apremilast may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Droxidopa | Droxidopa Droxidopa may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ceritinib | Ceritinib Digoxin may increase the bradycardic activities of Ceritinib. |
Belinostat Injection | Belinostat Injection The serum concentration of Digoxin can be increased when it is combined with Belinostat. |
Idelalisib | Idelalisib The serum concentration of Digoxin can be increased when it is combined with Idelalisib. |
Testosterone Injection | Testosterone Injection Digoxin may decrease the excretion rate of Testosterone which could result in a higher serum level. |
Vorapaxar | Vorapaxar Vorapaxar may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Suvorexant | Suvorexant Suvorexant may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Edoxaban | Edoxaban Edoxaban may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Caspofungin Injection | Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Digoxin. |
Methamphetamine | Methamphetamine Metamfetamine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tasimelteon | Tasimelteon Tasimelteon may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lanreotide Injection | Lanreotide Injection Digoxin may increase the bradycardic activities of Lanreotide. |
Nintedanib | Nintedanib The serum concentration of Digoxin can be increased when it is combined with Nintedanib. |
Risperidone Injection | Risperidone Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Risperidone. |
Palbociclib | Palbociclib Palbociclib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lenvatinib | Lenvatinib Lenvatinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Panobinostat | Panobinostat The serum concentration of Digoxin can be increased when it is combined with Panobinostat. |
Haloperidol Injection | Haloperidol Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Haloperidol. |
Deoxycholic Acid Injection | Deoxycholic Acid Injection Deoxycholic acid may increase the excretion rate of Digoxin which could result in a lower serum level and potentially a reduction in efficacy. |
Ivabradine | Ivabradine Ivabradine may increase the bradycardic activities of Digoxin. |
Amiloride | Amiloride Amiloride may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Isavuconazonium Injection | Isavuconazonium Injection The serum concentration of Digoxin can be increased when it is combined with Isavuconazonium. |
Macitentan | Macitentan Macitentan may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Flibanserin | Flibanserin Flibanserin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Rolapitant | Rolapitant Rolapitant may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Prednisolone | Prednisolone The risk or severity of adverse effects can be increased when Prednisolone is combined with Digoxin. |
Daclatasvir | Daclatasvir Daclatasvir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ziprasidone Injection | Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Ziprasidone. |
Penicillin G Procaine Injection | Penicillin G Procaine Injection Procaine benzylpenicillin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Eluxadoline | Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Digoxin. |
Cobimetinib | Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Digoxin. |
Osimertinib | Osimertinib The serum concentration of Digoxin can be increased when it is combined with Osimertinib. |
Ixazomib | Ixazomib Ixazomib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lesinurad | Lesinurad Lesinurad may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection The risk or severity of adverse effects can be increased when Amphotericin B is combined with Digoxin. |
Dexamethasone Injection | Dexamethasone Injection The risk or severity of adverse effects can be increased when Dexamethasone is combined with Digoxin. |
Brivaracetam Injection | Brivaracetam Injection Brivaracetam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Venetoclax | Venetoclax Venetoclax may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cobicistat | Cobicistat Cobicistat may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Midodrine | Midodrine Digoxin may increase the bradycardic, atrioventricular blocking (AV block), and arrhythmogenic activities of Midodrine. |
Selexipag | Selexipag The serum concentration of Selexipag can be increased when it is combined with Digoxin. |
Diphenhydramine Injection | Diphenhydramine Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Diphenhydramine. |
Calcifediol | Calcifediol The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Digoxin. |
Ergocalciferol | Ergocalciferol The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Ergocalciferol is combined with Digoxin. |
Doxercalciferol | Doxercalciferol The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Doxercalciferol is combined with Digoxin. |
Furosemide Injection | Furosemide Injection The risk or severity of adverse effects can be increased when Furosemide is combined with Digoxin. |
Rucaparib | Rucaparib Rucaparib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lixisenatide Injection | Lixisenatide Injection Lixisenatide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ribociclib | Ribociclib The risk or severity of QTc prolongation can be increased when Digoxin is combined with Ribociclib. |
Parathyroid Hormone Injection | Parathyroid Hormone Injection The risk or severity of adverse effects can be increased when Parathyroid hormone is combined with Digoxin. |
Doxepin (Insomnia) | Doxepin (Insomnia) Digoxin may decrease the excretion rate of Doxepin which could result in a higher serum level. |
Deutetrabenazine | Deutetrabenazine Digoxin may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level. |
Valbenazine | Valbenazine Valbenazine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Deflazacort | Deflazacort The risk or severity of adverse effects can be increased when Deflazacort is combined with Digoxin. |
Naldemedine | Naldemedine Naldemedine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Neratinib | Neratinib Neratinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Enasidenib | Enasidenib Enasidenib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Digoxin can be increased when it is combined with Inotuzumab ozogamicin. |
Benznidazole | Benznidazole Benznidazole may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Copanlisib Injection | Copanlisib Injection The serum concentration of Digoxin can be increased when it is combined with Copanlisib. |
Delafloxacin | Delafloxacin Delafloxacin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Abemaciclib | Abemaciclib The serum concentration of Abemaciclib can be increased when it is combined with Digoxin. |
Betrixaban | Betrixaban The serum concentration of Digoxin can be increased when it is combined with Betrixaban. |
Letermovir | Letermovir Digoxin may decrease the excretion rate of Letermovir which could result in a higher serum level. |
Tetrabenazine | Tetrabenazine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Tetrabenazine. |
Ertugliflozin | Ertugliflozin The serum concentration of Digoxin can be increased when it is combined with Ertugliflozin. |
Apalutamide | Apalutamide The serum concentration of Digoxin can be decreased when it is combined with Apalutamide. |
Penicillamine | Penicillamine The serum concentration of Digoxin can be decreased when it is combined with Penicillamine. |
Avatrombopag | Avatrombopag The serum concentration of Digoxin can be increased when it is combined with Avatrombopag. |
Baricitinib | Baricitinib Baricitinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lofexidine | Lofexidine Lofexidine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Plazomicin Injection | Plazomicin Injection Plazomicin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Eliglustat | Eliglustat The serum concentration of Digoxin can be increased when it is combined with Eliglustat. |
Encorafenib | Encorafenib The risk or severity of QTc prolongation can be increased when Digoxin is combined with Encorafenib. |
Binimetinib | Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Digoxin. |
Ivosidenib | Ivosidenib Ivosidenib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lusutrombopag | Lusutrombopag The serum concentration of Digoxin can be increased when it is combined with Lusutrombopag. |
Elagolix | Elagolix Digoxin may decrease the excretion rate of Elagolix which could result in a higher serum level. |
Eravacycline Injection | Eravacycline Injection Eravacycline can cause an increase in the absorption of Digoxin resulting in an increased serum concentration and potentially a worsening of adverse effects. |
Tafenoquine | Tafenoquine The serum concentration of Digoxin can be increased when it is combined with Tafenoquine. |
Dacomitinib | Dacomitinib Dacomitinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Duvelisib | Duvelisib The serum concentration of Digoxin can be increased when it is combined with Duvelisib. |
Omadacycline | Omadacycline Omadacycline can cause an increase in the absorption of Digoxin resulting in an increased serum concentration and potentially a worsening of adverse effects. |
Sarecycline | Sarecycline Sarecycline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Stiripentol | Stiripentol Stiripentol may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Talazoparib | Talazoparib The serum concentration of Digoxin can be increased when it is combined with Talazoparib. |
Gilteritinib | Gilteritinib The serum concentration of Digoxin can be increased when it is combined with Gilteritinib. |
Glasdegib | Glasdegib Glasdegib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Larotrectinib | Larotrectinib The serum concentration of Digoxin can be increased when it is combined with Larotrectinib. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection Paclitaxel may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Rifamycin | Rifamycin Rifamycin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Prucalopride | Prucalopride Prucalopride may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Erdafitinib | Erdafitinib The serum concentration of Digoxin can be increased when it is combined with Erdafitinib. |
Esomeprazole Injection | Esomeprazole Injection The serum concentration of Digoxin can be increased when it is combined with Esomeprazole. |
Cladribine | Cladribine Digoxin may decrease the cardiotoxic activities of Cladribine. |
Solriamfetol | Solriamfetol Solriamfetol may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Darolutamide | Darolutamide The serum concentration of Digoxin can be increased when it is combined with Darolutamide. |
Triclabendazole | Triclabendazole The risk or severity of QTc prolongation can be increased when Digoxin is combined with Triclabendazole. |
Entrectinib | Entrectinib The risk or severity of QTc prolongation can be increased when Digoxin is combined with Entrectinib. |
Pexidartinib | Pexidartinib The excretion of Digoxin can be decreased when combined with Pexidartinib. |
Istradefylline | Istradefylline The serum concentration of Digoxin can be increased when it is combined with Istradefylline. |
Pitolisant | Pitolisant Pitolisant may increase the QTc-prolonging activities of Digoxin. |
Fedratinib | Fedratinib Digoxin may decrease the excretion rate of Fedratinib which could result in a higher serum level. |
Lefamulin | Lefamulin Digoxin may increase the QTc-prolonging activities of Lefamulin. |
Phenytoin Injection | Phenytoin Injection The serum concentration of Digoxin can be decreased when it is combined with Phenytoin. |
Enfortumab vedotin-ejfv Injection | Enfortumab vedotin-ejfv Injection The serum concentration of Digoxin can be increased when it is combined with Enfortumab vedotin. |
Lasmiditan | Lasmiditan The serum concentration of Digoxin can be increased when it is combined with Lasmiditan. |
Ubrogepant | Ubrogepant The serum concentration of Digoxin can be increased when it is combined with Ubrogepant. |
Calcium Acetate | Calcium Acetate Calcium acetate may increase the arrhythmogenic and cardiotoxic activities of Digoxin. |
Tazemetostat | Tazemetostat The serum concentration of Digoxin can be increased when it is combined with Tazemetostat. |
Bempedoic Acid | Bempedoic Acid The excretion of Digoxin can be decreased when combined with Bempedoic acid. |
Selumetinib | Selumetinib The serum concentration of Digoxin can be increased when it is combined with Selumetinib. |
Rimegepant | Rimegepant The serum concentration of Digoxin can be increased when it is combined with Rimegepant. |
Tucatinib | Tucatinib Tucatinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Remdesivir Injection | Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Digoxin. |
Ripretinib | Ripretinib Ripretinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Capmatinib | Capmatinib The serum concentration of Digoxin can be increased when it is combined with Capmatinib. |
Lemborexant | Lemborexant The serum concentration of Digoxin can be increased when it is combined with Lemborexant. |
Fostemsavir | Fostemsavir The risk or severity of QTc prolongation can be increased when Digoxin is combined with Fostemsavir. |
Octreotide | Octreotide The serum concentration of Digoxin can be decreased when it is combined with Octreotide. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection Digoxin may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level. |
Pralsetinib | Pralsetinib Pralsetinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Relugolix | Relugolix The risk or severity of QTc prolongation can be increased when Digoxin is combined with Relugolix. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives Digoxin may increase the excretion rate of Drospirenone which could result in a lower serum level and potentially a reduction in efficacy. |
Vibegron | Vibegron The serum concentration of Digoxin can be increased when it is combined with Vibegron. |
Viloxazine | Viloxazine Viloxazine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tobramycin Injection | Tobramycin Injection Tobramycin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Fenoprofen | Fenoprofen Fenoprofen may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Indomethacin | Indomethacin The serum concentration of Digoxin can be increased when it is combined with Indomethacin. |
Mefenamic Acid | Mefenamic Acid Mefenamic acid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Naproxen | Naproxen Naproxen may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tolmetin | Tolmetin Tolmetin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sulindac | Sulindac Sulindac may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Trazodone | Trazodone The serum concentration of Digoxin can be increased when it is combined with Trazodone. |
Isotretinoin | Isotretinoin Digoxin may decrease the excretion rate of Isotretinoin which could result in a higher serum level. |
Sucralfate | Sucralfate Sucralfate can cause a decrease in the absorption of Digoxin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Sodium Bicarbonate | Sodium Bicarbonate The serum concentration of Digoxin can be decreased when it is combined with Sodium bicarbonate. |
Floxuridine | Floxuridine Floxuridine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Phenobarbital | Phenobarbital Phenobarbital may increase the excretion rate of Digoxin which could result in a lower serum level and potentially a reduction in efficacy. |
Metaxalone | Metaxalone Metaxalone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Methotrexate Injection | Methotrexate Injection Methotrexate may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Methsuximide | Methsuximide Methsuximide may increase the arrhythmogenic activities of Digoxin. |
Chlorpromazine | Chlorpromazine Chlorpromazine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Diazepam | Diazepam Diazepam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Oxazepam | Oxazepam Oxazepam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Flurazepam | Flurazepam Digoxin may decrease the excretion rate of Flurazepam which could result in a higher serum level. |
Clorazepate | Clorazepate Clorazepic acid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Lorazepam | Lorazepam Lorazepam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Carmustine | Carmustine Carmustine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Amantadine | Amantadine Amantadine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Codeine | Codeine Codeine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Phenelzine | Phenelzine Phenelzine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tetracycline | Tetracycline The serum concentration of Digoxin can be increased when it is combined with Tetracycline. |
Minocycline | Minocycline Minocycline can cause an increase in the absorption of Digoxin resulting in an increased serum concentration and potentially a worsening of adverse effects. |
Demeclocycline | Demeclocycline Demeclocycline can cause an increase in the absorption of Digoxin resulting in an increased serum concentration and potentially a worsening of adverse effects. |
Prochlorperazine | Prochlorperazine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Prochlorperazine. |
Thioridazine | Thioridazine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Thioridazine. |
Bleomycin | Bleomycin Bleomycin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sulfadiazine | Sulfadiazine Sulfadiazine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Methadone | Methadone Methadone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Benztropine | Benztropine Benzatropine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Colestipol | Colestipol The serum concentration of Digoxin can be decreased when it is combined with Colestipol. |
Maprotiline | Maprotiline Maprotiline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ibuprofen | Ibuprofen The serum concentration of Digoxin can be increased when it is combined with Ibuprofen. |
Orphenadrine | Orphenadrine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Orphenadrine. |
Azathioprine | Azathioprine Azathioprine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Methylphenidate | Methylphenidate Methylphenidate may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Amoxapine | Amoxapine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Amoxapine. |
Sulfasalazine | Sulfasalazine The serum concentration of Digoxin can be decreased when it is combined with Sulfasalazine. |
Hydrocortisone | Hydrocortisone The risk or severity of adverse effects can be increased when Hydrocortisone is combined with Digoxin. |
Doxorubicin | Doxorubicin Digoxin may decrease the excretion rate of Doxorubicin which could result in a higher serum level. |
Mechlorethamine | Mechlorethamine Digoxin may decrease the cardiotoxic activities of Mechlorethamine. |
Dactinomycin | Dactinomycin The serum concentration of Digoxin can be increased when it is combined with Dactinomycin. |
Phenazopyridine | Phenazopyridine Phenazopyridine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Carbamazepine | Carbamazepine Digoxin may decrease the excretion rate of Carbamazepine which could result in a higher serum level. |
Methyldopa | Methyldopa Methyldopa may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Clonidine | Clonidine Clonidine may increase the atrioventricular blocking (AV block) activities of Digoxin. |
Hydralazine | Hydralazine Hydralazine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cimetidine | Cimetidine Cimetidine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Gentamicin Injection | Gentamicin Injection The serum concentration of Digoxin can be increased when it is combined with Gentamicin. |
Warfarin | Warfarin Digoxin may decrease the excretion rate of Warfarin which could result in a higher serum level. |
Clonazepam | Clonazepam Clonazepam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Loperamide | Loperamide Loperamide may increase the arrhythmogenic activities of Digoxin. |
Promethazine | Promethazine Digoxin may decrease the excretion rate of Promethazine which could result in a higher serum level. |
Meclofenamate | Meclofenamate Meclofenamic acid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Daunorubicin | Daunorubicin Digoxin may decrease the excretion rate of Daunorubicin which could result in a higher serum level. |
Nitrofurantoin | Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Loxapine | Loxapine Loxapine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Chloroquine | Chloroquine Digoxin may decrease the excretion rate of Chloroquine which could result in a higher serum level. |
Quinine | Quinine The serum concentration of Digoxin can be increased when it is combined with Quinine. |
Ethosuximide | Ethosuximide Ethosuximide may increase the arrhythmogenic activities of Digoxin. |
Calcitriol | Calcitriol The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcitriol is combined with Digoxin. |
Triamterene | Triamterene Triamterene may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sulfinpyrazone | Sulfinpyrazone Sulfinpyrazone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Chlorothiazide | Chlorothiazide Chlorothiazide may increase the hypokalemic activities of Digoxin. |
Chlorthalidone | Chlorthalidone The risk or severity of adverse effects can be increased when Chlorthalidone is combined with Digoxin. |
Metolazone | Metolazone Metolazone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Isosorbide | Isosorbide Isosorbide may increase the excretion rate of Digoxin which could result in a lower serum level and potentially a reduction in efficacy. |
Clindamycin Injection | Clindamycin Injection The serum concentration of Digoxin can be increased when it is combined with Clindamycin. |
Secobarbital | Secobarbital Secobarbital may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Desipramine | Desipramine Digoxin may decrease the excretion rate of Desipramine which could result in a higher serum level. |
Amitriptyline | Amitriptyline Amitriptyline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Imipramine | Imipramine Digoxin may decrease the excretion rate of Imipramine which could result in a higher serum level. |
Probenecid | Probenecid Probenecid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Quinidine | Quinidine The serum concentration of Digoxin can be increased when it is combined with Quinidine. |
Procainamide | Procainamide Digoxin may increase the arrhythmogenic activities of Procainamide. |
Isoniazid | Isoniazid Isoniazid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pyrazinamide | Pyrazinamide Pyrazinamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Rifampin | Rifampin The serum concentration of Digoxin can be decreased when it is combined with Rifampicin. |
Disopyramide | Disopyramide Digoxin may increase the arrhythmogenic activities of Disopyramide. |
Valproic Acid | Valproic Acid The risk or severity of QTc prolongation can be increased when Digoxin is combined with Valproic acid. |
Tamoxifen | Tamoxifen Tamoxifen may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Mitomycin | Mitomycin Digoxin may decrease the cardiotoxic activities of Mitomycin. |
Butabarbital | Butabarbital Butabarbital may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Levothyroxine | Levothyroxine Levothyroxine may increase the excretion rate of Digoxin which could result in a lower serum level and potentially a reduction in efficacy. |
Liothyronine | Liothyronine The serum concentration of Liothyronine can be decreased when it is combined with Digoxin. |
Methimazole | Methimazole The serum concentration of Digoxin can be increased when it is combined with Methimazole. |
Propylthiouracil | Propylthiouracil The serum concentration of Digoxin can be increased when it is combined with Propylthiouracil. |
Chlorpropamide | Chlorpropamide Chlorpropamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tolbutamide | Tolbutamide Tolbutamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tolazamide | Tolazamide Tolazamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dinoprostone | Dinoprostone The excretion of Dinoprostone can be decreased when combined with Digoxin. |
Baclofen | Baclofen Baclofen may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Doxylamine | Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Digoxin. |
Cyproheptadine | Cyproheptadine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Cyproheptadine. |
Clemastine | Clemastine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Clemastine. |
Chlorpheniramine | Chlorpheniramine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Chlorpheniramine. |
Brompheniramine | Brompheniramine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Dexbrompheniramine. |
Ethambutol | Ethambutol Ethambutol may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Methyclothiazide | Methyclothiazide Methyclothiazide may increase the hypokalemic activities of Digoxin. |
Hydrochlorothiazide | Hydrochlorothiazide Hydrochlorothiazide may increase the hypokalemic activities of Digoxin. |
Dantrolene | Dantrolene The risk or severity of hyperkalemia can be increased when Digoxin is combined with Dantrolene. |
Chlorzoxazone | Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pyridoxine | Pyridoxine Pyridoxine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Folic Acid | Folic Acid Folic acid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Disulfiram | Disulfiram Disulfiram may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) Propranolol may increase the arrhythmogenic activities of Digoxin. |
Nortriptyline | Nortriptyline The risk or severity of QTc prolongation can be increased when Digoxin is combined with Nortriptyline. |
Spironolactone | Spironolactone The serum concentration of Digoxin can be increased when it is combined with Spironolactone. |
Amphotericin B Injection | Amphotericin B Injection The risk or severity of adverse effects can be increased when Amphotericin B is combined with Digoxin. |
Phytonadione | Phytonadione Phylloquinone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Amikacin Injection | Amikacin Injection Amikacin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Nadolol | Nadolol Nadolol may increase the arrhythmogenic activities of Digoxin. |
Cholestyramine Resin | Cholestyramine Resin The serum concentration of Digoxin can be decreased when it is combined with Cholestyramine. |
Allopurinol | Allopurinol Allopurinol may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Oxytocin Injection | Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Digoxin. |
Clomiphene | Clomiphene The serum concentration of Digoxin can be increased when it is combined with Clomifene. |
Flavoxate | Flavoxate Flavoxate may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Papaverine | Papaverine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Papaverine. |
Fluorouracil Injection | Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Digoxin is combined with Fluorouracil. |
Colchicine | Colchicine Colchicine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefaclor | Cefaclor Cefaclor may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefadroxil | Cefadroxil Cefadroxil may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection Cefazolin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cephalexin | Cephalexin Cephalexin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefoxitin Injection | Cefoxitin Injection Cefoxitin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dacarbazine | Dacarbazine Dacarbazine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Acetazolamide | Acetazolamide Acetazolamide may increase the excretion rate of Digoxin which could result in a lower serum level and potentially a reduction in efficacy. |
Nystatin | Nystatin The excretion of Digoxin can be decreased when combined with Nystatin. |
Cefotaxime Injection | Cefotaxime Injection Cefotaxime may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ketoconazole | Ketoconazole The serum concentration of Digoxin can be increased when it is combined with Ketoconazole. |
Pyrantel | Pyrantel Pyrantel may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Vincristine Injection | Vincristine Injection Vincristine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Captopril | Captopril The serum concentration of Digoxin can be increased when it is combined with Captopril. |
Dipyridamole | Dipyridamole Dipyridamole may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Vinblastine | Vinblastine Vinblastine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ethacrynic Acid | Ethacrynic Acid The risk or severity of adverse effects can be increased when Etacrynic acid is combined with Digoxin. |
Colistimethate Injection | Colistimethate Injection Colistimethate may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Metoprolol | Metoprolol Metoprolol may increase the arrhythmogenic activities of Digoxin. |
Hydroxyzine | Hydroxyzine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Hydroxyzine. |
Thiothixene | Thiothixene The risk or severity of QTc prolongation can be increased when Digoxin is combined with Thiothixene. |
Aspirin | Aspirin Acetylsalicylic acid may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Salsalate | Salsalate Salsalate may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Alprazolam | Alprazolam The serum concentration of Digoxin can be increased when it is combined with Alprazolam. |
Temazepam | Temazepam Temazepam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Triazolam | Triazolam Triazolam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dicyclomine | Dicyclomine Dicyclomine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Hyoscyamine | Hyoscyamine Digoxin may increase the arrhythmogenic activities of Hyoscyamine. |
Propantheline | Propantheline The serum concentration of Digoxin can be increased when it is combined with Propantheline. |
Trimethoprim | Trimethoprim The serum concentration of Digoxin can be increased when it is combined with Trimethoprim. |
Diltiazem | Diltiazem The serum concentration of Digoxin can be increased when it is combined with Diltiazem. |
Nifedipine | Nifedipine The serum concentration of Digoxin can be increased when it is combined with Nifedipine. |
Timolol | Timolol Timolol may increase the arrhythmogenic activities of Digoxin. |
Verapamil | Verapamil The serum concentration of Digoxin can be increased when it is combined with Verapamil. |
Atenolol | Atenolol Atenolol may increase the arrhythmogenic activities of Digoxin. |
Pindolol | Pindolol Pindolol may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cisplatin Injection | Cisplatin Injection Cisplatin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Diflunisal | Diflunisal Diflunisal may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Piroxicam | Piroxicam Piroxicam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Bumetanide | Bumetanide The risk or severity of adverse effects can be increased when Bumetanide is combined with Digoxin. |
Etoposide | Etoposide The serum concentration of Digoxin can be increased when it is combined with Etoposide. |
Glyburide | Glyburide Glyburide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Glipizide | Glipizide Glipizide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Indapamide | Indapamide Indapamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Amoxicillin | Amoxicillin Amoxicillin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Oxacillin Injection | Oxacillin Injection Oxacillin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pentoxifylline | Pentoxifylline Pentoxifylline may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pentamidine Injection | Pentamidine Injection Pentamidine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ceftriaxone Injection | Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Labetalol | Labetalol Labetalol may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Auranofin | Auranofin Auranofin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Leuprolide Injection | Leuprolide Injection Leuprolide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Gemfibrozil | Gemfibrozil Gemfibrozil may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ceftazidime Injection | Ceftazidime Injection Ceftazidime may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ketoprofen | Ketoprofen Ketoprofen may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefotetan Injection | Cefotetan Injection Cefotetan may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pimozide | Pimozide The risk or severity of QTc prolongation can be increased when Digoxin is combined with Pimozide. |
Enalapril | Enalapril The excretion of Enalapril can be decreased when combined with Digoxin. |
Flurbiprofen | Flurbiprofen Flurbiprofen may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Amiodarone | Amiodarone The serum concentration of Digoxin can be increased when it is combined with Amiodarone. |
Aztreonam Injection | Aztreonam Injection Aztreonam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Buspirone | Buspirone Digoxin may decrease the excretion rate of Buspirone which could result in a higher serum level. |
Ciprofloxacin | Ciprofloxacin Ciprofloxacin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Mesalamine | Mesalamine Mesalazine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Diclofenac | Diclofenac The serum concentration of Digoxin can be increased when it is combined with Diclofenac. |
Fluoxetine | Fluoxetine The risk or severity of QTc prolongation can be increased when Fluoxetine is combined with Digoxin. |
Nimodipine | Nimodipine Nimodipine may increase the arrhythmogenic activities of Digoxin. |
Clozapine | Clozapine Clozapine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Estazolam | Estazolam Estazolam may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Idarubicin | Idarubicin Digoxin may decrease the cardiotoxic activities of Idarubicin. |
Ofloxacin | Ofloxacin Ofloxacin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Didanosine | Didanosine Didanosine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Fludarabine Injection | Fludarabine Injection Digoxin may decrease the cardiotoxic activities of Fludarabine. |
Pentostatin Injection | Pentostatin Injection Pentostatin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Clarithromycin | Clarithromycin The serum concentration of Digoxin can be increased when it is combined with Clarithromycin. |
Benazepril | Benazepril The risk or severity of hyperkalemia can be increased when Digoxin is combined with Benazepril. |
Etodolac | Etodolac Etodolac may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Felodipine | Felodipine Felodipine may increase the arrhythmogenic activities of Digoxin. |
Fosinopril | Fosinopril Fosinopril may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Nabumetone | Nabumetone Nabumetone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Pravastatin | Pravastatin Pravastatin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Quinapril | Quinapril The risk or severity of hyperkalemia can be increased when Digoxin is combined with Quinapril. |
Ramipril | Ramipril The risk or severity of hyperkalemia can be increased when Ramipril is combined with Digoxin. |
Simvastatin | Simvastatin The serum concentration of Digoxin can be increased when it is combined with Simvastatin. |
Amlodipine | Amlodipine Amlodipine may increase the arrhythmogenic activities of Digoxin. |
Teniposide Injection | Teniposide Injection Digoxin may decrease the cardiotoxic activities of Teniposide. |
Itraconazole | Itraconazole The serum concentration of Digoxin can be increased when it is combined with Itraconazole. |
Lisinopril | Lisinopril Lisinopril may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Oxaprozin | Oxaprozin Oxaprozin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sotalol | Sotalol Sotalol may increase the arrhythmogenic activities of Digoxin. |
Bisoprolol | Bisoprolol The therapeutic efficacy of Digoxin can be increased when used in combination with Bisoprolol. |
Isradipine | Isradipine Isradipine may increase the arrhythmogenic activities of Digoxin. |
Omeprazole | Omeprazole The serum concentration of Digoxin can be increased when it is combined with Omeprazole. |
Cisapride | Cisapride The risk or severity of QTc prolongation can be increased when Digoxin is combined with Cisapride. |
Fluvastatin | Fluvastatin The excretion of Fluvastatin can be decreased when combined with Digoxin. |
Venlafaxine | Venlafaxine Venlafaxine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Fluvoxamine | Fluvoxamine Fluvoxamine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Nefazodone | Nefazodone The serum concentration of Digoxin can be increased when it is combined with Nefazodone. |
Lamotrigine | Lamotrigine Lamotrigine may increase the arrhythmogenic activities of Digoxin. |
Losartan | Losartan Losartan may increase the arrhythmogenic activities of Digoxin. |
Valacyclovir | Valacyclovir Valaciclovir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tramadol | Tramadol The risk or severity of adverse effects can be increased when Tramadol is combined with Digoxin. |
Vinorelbine Injection | Vinorelbine Injection Digoxin may decrease the cardiotoxic activities of Vinorelbine. |
Carboplatin Injection | Carboplatin Injection Carboplatin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Moexipril | Moexipril The risk or severity of QTc prolongation can be increased when Digoxin is combined with Moexipril. |
Lansoprazole | Lansoprazole The serum concentration of Digoxin can be increased when it is combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection Ifosfamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Nicardipine | Nicardipine Nicardipine may increase the arrhythmogenic activities of Digoxin. |
Bupropion | Bupropion Bupropion may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ticlopidine | Ticlopidine Ticlopidine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Saquinavir | Saquinavir The serum concentration of Digoxin can be increased when it is combined with Saquinavir. |
Metformin | Metformin The serum concentration of Digoxin can be increased when it is combined with Metformin. |
Dalteparin Injection | Dalteparin Injection The risk or severity of hyperkalemia can be increased when Digoxin is combined with Dalteparin. |
Nisoldipine | Nisoldipine Nisoldipine may increase the arrhythmogenic activities of Digoxin. |
Lamivudine | Lamivudine Lamivudine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Acarbose | Acarbose The serum concentration of Digoxin can be decreased when it is combined with Acarbose. |
Glimepiride | Glimepiride Glimepiride may increase the arrhythmogenic activities of Digoxin. |
Anastrozole | Anastrozole Digoxin may decrease the cardiotoxic activities of Anastrozole. |
Gemcitabine Injection | Gemcitabine Injection Gemcitabine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Indinavir | Indinavir Indinavir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Ritonavir | Ritonavir The bioavailability of Digoxin can be increased when combined with Ritonavir. |
Docetaxel Injection | Docetaxel Injection Digoxin may decrease the cardiotoxic activities of Docetaxel. |
Cidofovir Injection | Cidofovir Injection Cidofovir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Meropenem Injection | Meropenem Injection Meropenem may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Clomipramine | Clomipramine Digoxin may decrease the excretion rate of Clomipramine which could result in a higher serum level. |
Fosfomycin | Fosfomycin Fosfomycin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Mirtazapine | Mirtazapine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Digoxin. |
Trandolapril | Trandolapril The risk or severity of hyperkalemia can be increased when Digoxin is combined with Trandolapril. |
Topiramate | Topiramate Topiramate may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Valsartan | Valsartan The risk or severity of hyperkalemia can be increased when Valsartan is combined with Digoxin. |
Pramipexole | Pramipexole Pramipexole may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Donepezil | Donepezil Digoxin may increase the bradycardic activities of Donepezil. |
Nelfinavir | Nelfinavir Nelfinavir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Fexofenadine | Fexofenadine The serum concentration of Digoxin can be increased when it is combined with Fexofenadine. |
Azithromycin | Azithromycin The serum concentration of Digoxin can be increased when it is combined with Azithromycin. |
Loratadine | Loratadine Loratadine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Carvedilol | Carvedilol The serum concentration of Digoxin can be increased when it is combined with Carvedilol. |
Nilutamide | Nilutamide Nilutamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Flutamide | Flutamide Flutamide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Propafenone | Propafenone The serum concentration of Digoxin can be increased when it is combined with Propafenone. |
Raloxifene | Raloxifene The excretion of Raloxifene can be decreased when combined with Digoxin. |
Irbesartan | Irbesartan The risk or severity of hyperkalemia can be increased when Digoxin is combined with Irbesartan. |
Tamsulosin | Tamsulosin Tamsulosin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Quetiapine | Quetiapine Digoxin may decrease the excretion rate of Quetiapine which could result in a higher serum level. |
Cefepime Injection | Cefepime Injection Cefepime may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefprozil | Cefprozil Cefprozil may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cefpodoxime | Cefpodoxime Cefpodoxime may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Cetirizine | Cetirizine Cetirizine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tolcapone | Tolcapone Tolcapone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Citalopram | Citalopram The risk or severity of QTc prolongation can be increased when Digoxin is combined with Citalopram. |
Capecitabine | Capecitabine Capecitabine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Efavirenz | Efavirenz Efavirenz may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Abacavir | Abacavir Abacavir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Sildenafil | Sildenafil Sildenafil may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Trastuzumab Injection | Trastuzumab Injection Digoxin may decrease the cardiotoxic activities of Trastuzumab. |
Celecoxib | Celecoxib Celecoxib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Rosiglitazone | Rosiglitazone Rosiglitazone may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Tolterodine | Tolterodine Tolterodine may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Thalidomide | Thalidomide Digoxin may decrease the cardiotoxic activities of Thalidomide. |
Oseltamivir | Oseltamivir Oseltamivir may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Aluminum Hydroxide | Aluminum Hydroxide The serum concentration of Digoxin can be decreased when it is combined with Aluminum hydroxide. |
Colesevelam | Colesevelam Colesevelam can cause a decrease in the absorption of Digoxin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Balsalazide | Balsalazide Balsalazide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Nateglinide | Nateglinide Nateglinide may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Galantamine | Galantamine The risk or severity of QTc prolongation can be increased when Digoxin is combined with Galantamine. |
Rabeprazole | Rabeprazole The serum concentration of Digoxin can be increased when it is combined with Rabeprazole. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists