Skip to the answer

Magnesium Sulfate Heptahydrate

Magnesium sulfate is a magnesium salt used as an IV or injected medicine for low magnesium and for preventing and controlling seizures in preeclampsia and eclampsia, and as an oral product for occasional constipation.

Brand names Magnesium SulfateMagnesium Sulfate in WaterMagnesium Sulfate in 5% DextroseMagnesium Sulfate in DextroseSal Inglesa EPSOM SALT +1 more
Drug classes Calculi Dissolution Agent
Rx/OTC Forms 2
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 18 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 7, 2026
Magnesium Sulfate Heptahydrate at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Magnesium sulfate is a familiar magnesium salt given by injection in the hospital to correct low magnesium and, as the usual first choice, to prevent and control seizures in preeclampsia and eclampsia (it quiets nerve signals to muscles and calms the brain), and it is also sold as Epsom salts for occasional constipation. Most people on the injection notice flushing, sweating and sleepiness, while Epsom salts mainly bring a quick, loose bowel movement. With the injection, the thing to watch for is magnesium toxicity (slowed breathing, weak reflexes, low blood pressure), so the care team checks blood levels, reflexes, breathing and urine output closely.

Clinical pearls

  • Mix Epsom salts into a full 8-ounce glass of water, and stop after a week unless a doctor says otherwise.
  • Magnesium leaves the body only through the kidneys, so kidney problems mean lower doses and a higher toxicity risk.
  • If surgery or a C-section is possible, the anesthesia team needs to know, since magnesium strengthens muscle relaxants, opioids and propofol.
  • Continuous use in pregnancy beyond 5 to 7 days can lower the baby's calcium and affect bone development.
How we write & review this content — our editorial policy →
How you get itPrescription and over the counter
Comes asInjection, Other oral form
Earliest FDA record2000
Companies listing it with the FDA14
FDA label last updatedNov 4, 2024
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Magnesium Sulfate Heptahydrate, written from its FDA label.

What Magnesium Sulfate Heptahydrate is used for

▾

Magnesium sulfate is used in several ways, depending on the product.

  • Magnesium Sulfate Injection (IV or IM) replaces magnesium in deficiency, especially acute low magnesium with tetany (muscle spasms).
  • Magnesium Sulfate Injection can be added to total parenteral nutrition (TPN) to correct or prevent low magnesium.
  • Magnesium Sulfate Injection and Magnesium Sulfate in Water prevent and control seizures in preeclampsia and eclampsia.
  • Magnesium Sulfate in Dextrose prevents eclampsia in preeclampsia and treats and prevents recurrent seizures in eclampsia.
  • Epsom Salts, Sal Inglesa and Rapidol Sal Inglesa (oral) relieve occasional constipation.

How Magnesium Sulfate Heptahydrate works

▾

Magnesium blocks communication between nerves and muscles by lowering the amount of acetylcholine released. This is how it prevents and controls seizures in preeclampsia and eclampsia.

It also depresses the central nervous system and relaxes blood vessels.

Magnesium Sulfate Heptahydrate dosage

▾

Injectable products are given by healthcare professionals, either into a vein or, for some products, into a muscle. IV solutions are diluted, and dosing is adjusted to your response and magnesium levels.

  • Magnesium Sulfate in Dextrose is given by infusion pump, with magnesium levels checked.
  • Oral products are dissolved in a full glass of water and taken once daily or in divided doses.
  • Epsom Salts: no more than 2 doses per day.

Follow your prescriber's and the label's directions.

Dosing details from the FDA-approved label

From the Magnesium Sulfate Heptahydrate prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Mild magnesium deficiency
    • Usual adult dose is 1 g, equivalent to 8.12 mEq of magnesium (2 mL of the 50% solution) injected IM every six hours for four doses (equivalent to a total of 32.5 mEq of magnesium per 24 hours)
    • caution must be observed to prevent exceeding the renal excretory capacity
  • Severe hypomagnesemia
    • As much as 250 mg (approximately 2 mEq) per kg of body weight (0.5 mL of the 50% solution) may be given IM within a period of four hours if necessary
    • Alternatively, 5 g (approximately 40 mEq) added to one liter of 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP for slow IV infusion over a three-hour period
    • caution must be observed to prevent exceeding the renal excretory capacity
  • Hyperalimentation (TPN), adults
    • Maintenance dose ranges from 8 to 24 mEq (1 to 3 g) daily
    • maintenance requirements for magnesium are not precisely known
  • Hyperalimentation (TPN), infants
    • Range is 2 to 10 mEq (0.25 to 1.25 g) daily
    • maintenance requirements for magnesium are not precisely known
  • Severe pre-eclampsia or eclampsia
    • Total initial dose is 10 to 14 g of magnesium sulfate
    • IV: 4 to 5 g in 250 mL of 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP, with simultaneous IM doses of up to 10 g (5 g or 10 mL of undiluted 50% solution in each buttock)
    • Alternatively initial IV dose of 4 g diluted to 10 or 20% injected over three to four minutes
    • Subsequently 4 to
    • Maximum: A total daily (24 hr) dose of 30 to 40 g should not be exceeded
    • severe renal insufficiency: maximum dosage is 20 grams/48 hours with frequent serum magnesium concentrations; use beyond 5 to 7 days in pregnancy can cause fetal abnormalities
  • Barium poisoning (counteracting muscle-stimulating effects)
    • Usual dose is 1 to 2 g given IV
  • Seizures associated with epilepsy, glomerulonephritis or hypothyroidism
    • Usual adult dose is 1 g administered IM or IV
  • Paroxysmal atrial tachycardia
    • Usual dose is 3 to 4 g (30 to 40 mL of a 10% solution) administered IV over 30 seconds with extreme caution
    • use only if simpler measures have failed and there is no evidence of myocardial damage
  • Reduction of cerebral edema
    • 2.5 g (25 mL of a 10% solution) is given IV
Read the label’s full dosing text

DOSAGE AND ADMINISTRATION: Dosage of magnesium sulfate must be carefully adjusted according to individual requirements and response, and administration of the drug should be discontinued as soon as the desired effect is obtained. Both IV and IM administration are appropriate. IM administration of the undiluted 50% solution results in therapeutic plasma levels in 60 minutes, whereas IV doses will provide a therapeutic level almost immediately. The rate of IV injection should generally not exceed 150 mg/minute (1.5 mL of a 10% concentration or its equivalent), except in severe eclampsia with seizures (see below). Continuous maternal administration of magnesium sulfate injection in pregnancy beyond 5 to 7 days can cause fetal abnormalities. Solutions for IV infusion must be diluted to a concentration of 20% or less prior to administration. The diluents commonly used are 5% Dextrose Injection, USP and 0.9% Sodium Chloride Injection, USP. Deep IM injection of the undiluted (50%) solution is appropriate for adults, but the solution should be diluted to a 20% or less concentration prior to such injection in children. In Magnesium Deficiency In the treatment of mild magnesium deficiency, the usual adult dose is 1 g, equivalent to 8.12 mEq of magnesium (2 mL of the 50% solution) injected IM every six hours for four doses (equivalent to a total of 32.5 mEq of magnesium per 24 hours). For severe hypomagnesemia, as much as 250 mg (approximately 2 mEq) per kg of body weight (0.5 mL of the 50% solution) may be given IM within a period of four hours if necessary. Alternatively, 5 g (approximately 40 mEq) can be added to one liter of 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP for slow IV infusion over a three-hour period. In the treatment of deficiency states, caution must be observed to prevent exceeding the renal excretory capacity. In Hyperalimentation In TPN, maintenance requirements for magnesium are not precisely known. The maintenance dose used in adults ranges from 8 to 24 mEq (1 to 3 g) daily; for infants, the range is 2 to 10 mEq (0.25 to 1.25 g) daily. In Pre-eclampsia or Eclampsia In severe pre-eclampsia or eclampsia, the total initial dose is 10 to 14 g of magnesium sulfate. Intravenously, a dose of 4 to 5 g in 250 mL of 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP may be infused.

Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →

Magnesium Sulfate Heptahydrate side effects

▾

Most side effects come from magnesium building up in the body.

Common side effects

  • Flushing
  • Sweating
  • Low blood pressure
  • Reduced reflexes
  • Low body temperature
  • Lethargy, sedation or sleepiness
  • Visual disturbances
  • Slowed heart rate

When to get medical help

  • Trouble breathing, a slowed breathing rate, or weak reflexes can be signs of magnesium toxicity and need immediate attention.
  • Severe weakness, trouble swallowing, drooping eyelids or facial droop in someone with myasthenia gravis can signal a life-threatening myasthenic crisis.
  • Signs of low calcium, such as muscle spasms (tetany), should be reported.
  • Shortness of breath may point to fluid in the lungs (pulmonary edema).
  • With the oral laxative, stop and ask a doctor if you have rectal bleeding or no bowel movement after use.
  • With the oral laxative, ask a doctor if you need it for more than a week.

Slowed breathing, circulatory collapse, fluid in the lungs, low calcium with muscle spasms, or myasthenic crisis need urgent medical care.

Magnesium Sulfate Heptahydrate warnings and precautions

▾
  • Magnesium toxicity: can cause breathing problems, low blood pressure and loss of reflexes. Levels and signs are monitored, and calcium is kept ready to reverse it.
  • Pregnancy: use beyond 5 to 7 days can cause low calcium and bone problems in the baby.
  • Kidney problems: raise the risk of toxicity and aluminum buildup.
  • Myasthenia gravis: can trigger a life-threatening myasthenic crisis.
  • Dextrose products: can raise blood sugar.
  • Oral laxative: do not use for more than a week unless directed.

Magnesium Sulfate Heptahydrate interactions

▾

Some medicines can add to magnesium's effects or change magnesium levels.

  • Neuromuscular blocking agents: stronger, longer muscle relaxation.
  • Narcotics and propofol: stronger, longer pain relief and sedation.
  • Dihydropyridine calcium channel blockers such as nifedipine: blood pressure may drop too far.
  • Terbutaline and nifedipine as unapproved labor-delaying drugs: serious problems including lung fluid and low blood pressure.
  • Alcohol, aminoglycosides, amphotericin B, cisplatin, cyclosporine, digitalis and diuretics: can cause magnesium loss.
  • Salicylates and alkali carbonates: incompatible in the same IV line as Magnesium Sulfate in 5% Dextrose.

Interactions listed in the FDA-approved label

From the Magnesium Sulfate Heptahydrate prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Neuromuscular blocking agents (succinylcholine, atracurium, cisatracurium, pancuronium, rocuronium, vecuronium): Potentiation and prolongation of neuromuscular blockade is possible. Monitor respiration and depth of neuromuscular blockade frequently (e.g., train-of-four); adjust the blocker dosage; the amount of reversal agent required may also be increased.
  • Narcotics and/or propofol: Potentiation and prolongation of analgesia and CNS depression is possible. Monitor depth of CNS depression frequently using a reliable instrument; adjust narcotic and/or propofol dosage to maintain desired analgesia and sedation.
  • Dihydropyridine calcium channel blockers (amlodipine, clevidipine, felodipine, isradipine, nicardipine, nifedipine, nimodipine, nisoldipine): An exaggerated hypotensive response is possible. Monitor vital signs (heart rate, blood pressure, respiration) frequently; supportive care and/or discontinuation of the calcium channel blocker may be required.
  • Drugs that may induce magnesium loss (alcohol, aminoglycosides, amphotericin B, cisplatin, cyclosporine, digitalis, loop diuretics, thiazide diuretics): Reduced magnesium concentrations may impact efficacy. Monitor magnesium concentrations frequently and adjust the dosage to maintain concentrations in the target range.
  • Streptomycin, tetracycline and tobramycin: Magnesium may reduce the antibiotic activity of these drugs when given together.
Read the label’s full interactions text

7 DRUG INTERACTIONS Table 1 presents the potential clinical impact of medications that may be commonly administered concomitantly with Magnesium Sulfate in 5% Dextrose Injection in the clinical setting. Table 1: Potential Clinically Significant Drug Interactions with Magnesium Sulfate in 5% Dextrose Injection For drug incompatibility information [see Dosage and Administration (2.4) ] . Neuromuscular Blocking Agents Clinical Impact: Potentiation and prolongation of neuromuscular blockade is possible with the concomitant use of magnesium sulfate and neuromuscular blocking agents [see Clinical Pharmacology (12.2) ] . The underlying mechanism of this interaction may involve suppression of peripheral neuromuscular function by decreasing acetylcholine release, reduction of endplate sensitivity, and decreased muscle fiber excitability with magnesium sulfate therapy. Intervention: Monitor respiration and the depth of neuromuscular blockade frequently (e.g., train-of-four monitoring) when a neuromuscular blocking agent is used concomitantly with Magnesium Sulfate in 5% Dextrose Injection. Adjust the dosage of the neuromuscular blocking agent accordingly to maintain the desired level of musculoskeletal activity. The amount of reversal agent(s) required to achieve adequate reversal of the neuromuscular blocking agent(s) may also be increased. Examples: Depolarizing neuromuscular blockers: succinylcholine Non-depolarizing neuromuscular blockers: atracurium, cisatracurium, pancuronium, rocuronium, vecuronium Narcotics and/or Propofol Clinical Impact: Potentiation and prolongation of analgesia and CNS depression is possible with the concomitant use of Magnesium Sulfate in 5% Dextrose Injection with narcotics and/or propofol. The potential for magnesium sulfate to affect other CNS depressants is unknown [see Clinical Pharmacology (12.2) ] . The underlying mechanism of this interaction may involve antagonism of N-methyl-D-aspartate (NMDA) by magnesium sulfate therapy.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

Check Magnesium Sulfate Heptahydrate against a supplement or herb →

Before taking Magnesium Sulfate Heptahydrate

▾
  • Not for people with heart block, myocardial damage, diabetic coma or myasthenia gravis (Magnesium Sulfate in 5% Dextrose Injection).
  • Tell your team about kidney problems.
  • Use caution with diabetes or prediabetes for dextrose-containing products.
  • Pregnancy: prolonged use can harm the baby; not approved for preterm labor.
  • Breastfeeding: IV magnesium raises milk levels only slightly.
  • Children: oral dosing depends on age, and children under 6 need a doctor's guidance or should not use some oral products.
  • Liver problems: no dose adjustment is needed.

Magnesium Sulfate Heptahydrate overdose

▾

Too much magnesium can cause low blood pressure, difficulty breathing and loss of the knee-jerk reflex. At higher levels it can cause respiratory paralysis, cardiac arrest and heart rhythm changes. Treatment is to stop the infusion, give an injectable calcium salt, and provide artificial respiration if needed.

What Magnesium Sulfate Heptahydrate does in the body

▾

After IV dosing, the anticonvulsant effect begins right away and lasts about 30 minutes. Effective blood levels for seizure control range from 2.5 to 7.5 mEq per liter. Reflexes begin to weaken above 4 mEq per liter and may disappear near 10 mEq per liter.

How your body processes Magnesium Sulfate Heptahydrate

▾

IV magnesium is absorbed immediately. It is not metabolized, and about 30% is bound to albumin. The kidneys clear it, so kidney problems raise levels. In women with preeclampsia the half-life is about 4 to 5 hours. IM injection of the undiluted solution reaches therapeutic levels in about 60 minutes.

How to store Magnesium Sulfate Heptahydrate

▾

Store at 20° to 25°C (68° to 77°F); excursions permitted between 15° to 30°C (59° to 86°F). Protect from freezing.

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

Magnesium Sulfate Heptahydrate: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Magnesium Sulfate Heptahydrate — the kind of thing our pharmacy team would talk through with you at the counter.

What is magnesium sulfate used for?

▾
It depends on the product. Injections treat low magnesium and prevent and control seizures in preeclampsia and eclampsia. Oral products such as Epsom Salts relieve occasional constipation.

How do I take the oral laxative forms?

▾
Dissolve the dose in a full glass (8 ounces) of water and drink it, with extra liquid as directed. A bowel movement usually comes in ½ to 6 hours. Follow the age-based package directions, and don't use it for more than a week unless a doctor says so.

What side effects should I expect with the injection?

▾
Flushing, sweating, low blood pressure, drowsiness and weaker reflexes are the most common. Your care team watches for these and checks your magnesium levels.

When should I get help right away?

▾
Trouble breathing, a slowed breathing rate, severe weakness or trouble swallowing need urgent attention. With the oral laxative, stop and call a doctor if you have rectal bleeding or no bowel movement.

Is it safe in pregnancy?

▾
For preeclampsia and eclampsia it is used in pregnancy. But continuous use beyond 5 to 7 days can cause low calcium and bone problems in the baby. It is not approved for preterm labor.

Do my other medicines matter?

▾
Yes. Tell your team about anesthesia drugs, narcotics, propofol, nifedipine or similar blood pressure medicines, and drugs like diuretics, digitalis or cyclosporine, because they can change magnesium's effects or levels.

Is Magnesium Sulfate Heptahydrate available over the counter?

▾
Both. Some Magnesium Sulfate Heptahydrate products are sold over the counter and others need a prescription. According to their FDA listings, the other oral form form is sold over the counter and the injection form needs a prescription. The package says which kind you have. Your pharmacist can tell you which product is right for you.

When was Magnesium Sulfate Heptahydrate first available?

▾
The earliest FDA record we hold for Magnesium Sulfate Heptahydrate is from 2000: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Magnesium Sulfate Heptahydrate was first used.

Who makes Magnesium Sulfate Heptahydrate?

▾
14 companies currently list Magnesium Sulfate Heptahydrate products in the FDA's NDC Directory, including Fresenius Kabi USA, LLC, B. Braun Medical Inc., Baxter Healthcare Corporation. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Magnesium Sulfate Heptahydrate on HelloPharmacist

🌿Drug & Supplement CheckerMagnesium Sulfate Heptahydrate vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Magnesium Sulfate Heptahydrate NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
Detailed data & references for Magnesium Sulfate Heptahydrate Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Magnesium Sulfate Heptahydrate forms and strengths (how it comes)

Magnesium Sulfate Heptahydrate is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Magnesium Sulfate Heptahydrate inactive ingredients by manufacturer.

Injection

Into a muscle · Into a vein
Brands Magnesium Sulfate Magnesium Sulfate in 5% Dextrose Magnesium Sulfate in Dextrose Magnesium Sulfate in Water
How this form is used
What it may be used for
  • Magnesium Sulfate Injection is used to replace magnesium in deficiency and to correct or prevent low magnesium in total parenteral nutrition (TPN).
  • Magnesium Sulfate Injection is also used to prevent and control seizures in preeclampsia and eclampsia.
  • Magnesium Sulfate in Dextrose is used to prevent eclampsia in preeclampsia and to treat and prevent recurrent seizures in eclampsia.
  • Magnesium Sulfate in Water is used to prevent and control seizures in preeclampsia and eclampsia.
Important instructions
  • Magnesium Sulfate in Dextrose is given by IV infusion pump, with magnesium levels checked to adjust the dose.
  • Magnesium Sulfate in Dextrose is not recommended beyond 5 to 7 days.
  • Magnesium Sulfate in Water is for intravenous use only.
  • Magnesium Sulfate Injection IV solutions must be diluted before infusion.
Available strengths 9 strengths
10 mg/mL 40 mg/mL 80 mg/mL 500 mg/mL 1 g/100 mL 2 g/50 mL
Show 3 more strengths Show fewer strengths
3 g/100 mL 4 g/50 mL 4 g/100 mL
60 FDA-listed product records ⓘ

Other oral form

By mouth
Brands Rapidol Sal Inglesa
How this form is used
What it may be used for
  • Rapidol Sal Inglesa is used for relief of occasional constipation, usually producing a bowel movement in ½ to 6 hours.
  • Sal Inglesa is used for relief of occasional constipation, usually producing a bowel movement in ½ to 6 hours.
Important instructions
  • Sal Inglesa is dissolved in a full glass (8 oz) of water and can be taken once daily or in divided doses.
  • Sal Inglesa is not recommended for children under 6.
  • Rapidol Sal Inglesa: drink a full glass of liquid with each dose; consult a doctor for children under 6.
Available strengths 1 strength
1 g/g
2 FDA-listed product records ⓘ

Magnesium Sulfate Heptahydrate on the U.S. market: products, makers and brands

How Magnesium Sulfate Heptahydrate appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

14 companies list 27 Magnesium Sulfate Heptahydrate product records with the FDA, mostly as injection, other oral form; the earliest marketing or approval year on record is 2000. Brand names on the directory include Magnesium Sulfate, Magnesium Sulfate in Water, Magnesium Sulfate in 5% Dextrose and 3 more; the rest are generics.

2
Dose forms ⓘ
14
Labelers (makers, repackagers, distributors)
6
Brand names
27
FDA-listed product records ⓘ
2000
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Crystal (3) · Granule (2) · Powder (2) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Fresenius Kabi USA, LLC19%
B. Braun Medical Inc.15%
Baxter Healthcare Corporation15%
Medical Purchasing Solutions, LLC11%
Gland Pharma Limited7%
Camber Pharmaceuticals, Inc.4%
Other makers30%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Magnesium Sulfate Heptahydrate is used (Medicaid data)

A general measure of how commonly Magnesium Sulfate Heptahydrate is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Magnesium Sulfate Heptahydrate is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

113,083
Medicaid prescriptions filled (Q1–Q4 2025)
$18.1M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Magnesium Sulfate Heptahydrate prescribed? Of the 1,601 medications we measure, Magnesium Sulfate Heptahydrate ranks #491 by Medicaid prescriptions — more than 69% of them.

Where Magnesium Sulfate Heptahydrate ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #491 of 1,601
#486 Pseudoephedrine 118,552 Rx #487 Rifaximin 118,294 Rx #488 Modafinil 117,062 Rx #489 Palonosetron Injection 116,599 Rx #490 Cefpodoxime 115,402 Rx #491 Magnesium Sulfate Hept... 113,083 Rx #492 Nystatin and Triamcino... 112,193 Rx #493 Vancomycin Injection 112,053 Rx #494 Atropine 111,807 Rx #495 Lifitegrast Ophthalmic 109,594 Rx #496 Midazolam Nasal Spray 109,459 Rx

Utilization by Magnesium Sulfate Heptahydrate product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

Other Magnesium Sulfate Heptahydrate products — combination packs and listings not yet matched to a specific clinical product (kept visible so every prescription is accounted for)

113,083 Medicaid prescriptions (Q1–Q4 2025) 100% of Magnesium Sulfate Heptahydrate prescriptions shown $18.1M gross reimbursement (before rebates) ≈ $160 per prescription (gross)

Summed across the 24 of 87 listed NDC products with Medicaid activity.

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Magnesium Sulfate Heptahydrate, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 24 of 87 listed Magnesium Sulfate Heptahydrate NDCs with Medicaid activity.

Compare Magnesium Sulfate Heptahydrate products

A representative set of FDA-listed product records for Magnesium Sulfate Heptahydrate — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 27 of 27 products — FDA National Drug Code Directory. See every product, package size and price: browse all 27 Magnesium Sulfate Heptahydrate NDCs →

Magnesium Sulfate Heptahydrate side effects reported to the FDA (FAERS)

After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Magnesium Sulfate Heptahydrate — a signal of what to watch for, not proof the drug caused it.

The effects most often named in FDA reports that mention Magnesium Sulfate Heptahydrate are nausea, pyrexia, pain; about 89% of the reports were classed as serious. These are voluntary reports, so they show what people report, not how often it happens.

13,457
Reports mentioning it
89%
Reported as serious
12
Distinct effects shown
Most reported effects
Nausea
868
Pyrexia
801
Pain
741
Foetal Exposure During Pregnancy
689
Diarrhoea
677
Premature Baby
672
Dyspnoea
616
Hypotension
571
Anaemia
562
Vomiting
541
Age groups
Adult · 912Elderly · 702Neonate · 401Infant · 63Child · 55Adolescent · 39

Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Magnesium Sulfate Heptahydrate in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.

Magnesium Sulfate Heptahydrate recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list no Magnesium Sulfate Heptahydrate recalls since July 2021.

✅No Magnesium Sulfate Heptahydrate recalls on record since July 2021

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

Magnesium Sulfate Heptahydrate brand names

Magnesium Sulfate Heptahydrate is sold under 6 brand names in the FDA directory — Magnesium Sulfate, Magnesium Sulfate in Water, Magnesium Sulfate in 5% Dextrose, Magnesium Sulfate in Dextrose and others. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Magnesium Sulfate Magnesium Sulfate in Water Magnesium Sulfate in 5% Dextrose Magnesium Sulfate in Dextrose Sal Inglesa EPSOM SALT Rapidol Sal Inglesa

Who makes Magnesium Sulfate Heptahydrate: manufacturers and labelers

14 companies list Magnesium Sulfate Heptahydrate products with the FDA. By number of product records, the largest are Fresenius Kabi USA, LLC, B. Braun Medical Inc., Baxter Healthcare Corporation. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Fresenius Kabi USA, LLC 5 B. Braun Medical Inc. 4 Baxter Healthcare Corporation 4 Medical Purchasing Solutions, LLC 3 Gland Pharma Limited 2 Camber Pharmaceuticals, Inc. 1 Civica, Inc. 1 Henry Schein, Inc. 1 Menper Distributors, Inc 1 Pharmadel LLC 1 ProPharma Distribution 1 Remedyrepack Inc. 1 Sagent Pharmaceuticals 1 Sun Pharmaceutical Industries, Inc. 1

Sources for this Magnesium Sulfate Heptahydrate page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Nov 4, 2024
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Magnesium Sulfate Heptahydrate.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Magnesium Sulfate Heptahydrate after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
18
Finished products in the current FDA directory
27
Companies listing them (makers, repackagers, distributors)
14
FDA labeler codes behind them ⓘ
14
Linked representative label ⓘ
B. Braun Medical Inc.
Linked label effective
Nov 4, 2024
Composite sections available
24
Linked SPL Set ID
4876dcd9-5e8f-47ed-af4f-6a4009ccffd1
Linked SPL Document ID
27f278a7-1ccc-4f74-99bd-2e9c806d4663
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. B. Braun Medical Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →