7,8-benzoflavone - Venclexta (Venetoclax) Interaction

Herbal: 7,8-benzoflavone

Drug: Venetoclax
Brand names: Venclexta

Medical Content Editor
Last updated Apr 13, 2024

Interaction Details

There were no interactions found between Venetoclax and 7,8-benzoflavone. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.

Still looking for more information about combining Venetoclax and 7,8-benzoflavone? Ask Dr. Brian Staiger about it by contacting him directly.

7,8-benzoflavone Overview

7,8-Benzoflavone acts as a steroidal aromatase inhibitor, which means it helps increase testosterone levels by blocking the conversion of testosterone to estrogen. This can be particularly beneficial when used alongside anabolic steroids to minimize side effects like gynecomastia caused by excess testosterone converting to estrogen. However, it's important to note that the World Anti-Doping Agency (WADA) has banned the use of aromatase inhibitors in sports to maintain fairness and integrity in athletic competition. Moreover, the consumption of dietary supplements containing aromatase inhibitors can pose significant risks. Adverse effects linked to these inhibitors encompass aggressive behavior, adrenal insufficiency, reduced bone maturation and growth rates, diminished sperm production, infertility, kidney failure, and liver dysfunction. The use of aromatase inhibitors (of which many are available by prescription) should be under the supervision of a medical professional.
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Venetoclax Overview

  • Venetoclax is used alone or in combination with obinutuzumab (Gazyva) or rituximab (Rituxan) to treat certain types of chronic lymphocytic leukemia (CLL; a type of cancer that begins in the white blood cells) or certain types of small lymphocytic lymphoma (SLL; a type of cancer that begins mostly in the lymph nodes). It is also used in combination with either azacitidine (Vidaza), decitabine (Dacogen), or cytarabine as a first treatment for acute myeloid leukemia (AML; a type of cancer that begins in the white blood cells) in people 75 years of age or older, or in adults who have medical conditions that prevents them from being treated with other chemotherapy medications. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It works by blocking the action of a certain protein in the body that helps cancer cells survive. This helps to kill cancer cells.

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7,8-benzoflavone - More Interactions

7,8-benzoflavone interacts with 0 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Dr. Brian Staiger, PharmD

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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