Agar - Aricept (Donepezil) Interaction
Herbal: Agar
Also Known As: Agar-Agar, Agarose, Agarose Gel, Agaropectin, Agarweed, Algue de Java, Chinese Gelatin, Colle du Japon, Gelosa, Gélose, Japanese Isinglas, Kanten Diet, Kanten Jelly, Kanten Plan, Layor Carang, Mousse de Ceylan, Mousse de Jaffna, Qion Zhi, Seaweed Gelatin, Vegetable Gelatin
Drug: Donepezil
Brand names:
Aricept, Adlarity
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Donepezil is classified as belonging to the following category: Oral Drugs
Agar forms a thick gel, which may disrupt the absorption of nutrients and medications. Animal research suggests that consuming a diet consisting of 5% to 10% agar alters the absorption of nutrients from the diet. In one study, consuming a diet composed of 10% agar reduced the absorption of all evaluated minerals. Theoretically, agar may also impair the absorption of oral drugs.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Kondo H, Osada A. Influence of dietary fiber on the bioavailability of zinc in rats. Biomed Environ Sci. 1996 Sept;9(2-3):204-8.
- Harmuth-Hoene, A. E. and Schelenz, R. Effect of dietary fiber on mineral absorption in growing rats. J Nutr 1980;110(9):1774-1784.
Agar Overview
Agar is a type of polysaccharide that is extracted from red algae. It is used as a gelling agent in food, pharmaceuticals, and other products. In cooking, agar is commonly used to make jellies, puddings, and other desserts. It is also used in scientific laboratories as a solid growth medium for microorganisms (i.e., an agar petri dish). Agar is a vegetarian alternative to gelatin, and is a food rich in certain minerals, vitamins, and dietary fiber.
Donepezil Overview
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Donepezil is used to treat dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and may cause changes in mood and personality) in people who have Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Donepezil is in a class of medications called cholinesterase inhibitors. It improves mental function (such as memory, attention, the ability to interact with others, speak, think clearly, and perform regular daily activities) by increasing the amount of a certain naturally occurring substance in the brain. Donepezil may improve the ability to think and remember or slow the loss of these abilities in people who have AD. However, donepezil will not cure AD or prevent the loss of mental abilities at some time in the future.
Agar - More Interactions
Agar interacts with 1987 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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