Interaction Details

There were no interactions found between Nifedipine and Alchemilla. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Nifedipine and Alchemilla? Ask Dr. Brian Staiger about it by contacting him directly.

Alchemilla Overview

Alchemilla Alchemilla, a perennial herb found throughout Europe, is traditionally used orally for gastrointestinal issues, inflammation, and as a diuretic. Its above-ground parts are also used topically for their astringent properties. Alchemilla contains 6-16% tannins (ellagic and gallic acids) and 2.22% flavonoids (quercetin, luteolin, and proanthocyanidins). Studies show that alchemilla's aqueous extracts have antioxidant effects, countering lipid peroxidation and scavenging superoxide anions. In dermatology, alchemilla extracts inhibit proteolytic enzymes and promote fibroblast migration, potentially aiding in wound healing. A small human study suggests that alchemilla extract in gels improves skin moisturization, particularly when skin is pre-treated with drying agents like sodium laurel sulfate, although the exact mechanism is unclear. Most dietary supplements that contain Alchemilla refer to it solely as 'Lady's Mantle'.
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Nifedipine Overview

  • Nifedipine is used to treat high blood pressure and to control angina (chest pain). Nifedipine is in a class of medications called calcium-channel blockers. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. It controls chest pain by increasing the supply of blood and oxygen to the heart.

  • High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

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Alchemilla - More Interactions

Alchemilla interacts with 183 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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