Alpha-linolenic Acid (ala) - Eliquis (Apixaban) Interaction

Herbal: Alpha-linolenic Acid (ala)
Also Known As: ALA, R-alpha-linolenic acid

Drug: Apixaban
Brand names: Eliquis

Medical Content Editor
Last updated Apr 13, 2024

Interaction Details

There were no interactions found between Apixaban and Alpha-linolenic Acid (ala). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.

Still looking for more information about combining Apixaban and Alpha-linolenic Acid (ala)? Ask Dr. Brian Staiger about it by contacting him directly.

Alpha-linolenic Acid (ala) Overview

Alpha-linolenic acid (ALA) is an essential omega-3 fatty acid. It is primarily found in vegetable oils like flaxseed, canola, and soybean oils, as well as in red meat, dairy products, margarines, and salad dressings containing vegetable oils. Walnuts and other edible nuts are also significant sources of ALA, along with smaller amounts in green leafy vegetables and chocolate. ALA is present in human breast milk, infant formulas, and intravenous fat emulsions. The body converts ALA into longer and more unsaturated omega-3 fatty acids, such as EPA and DHA, with conversion rates typically low but possibly as high as 30%. However, in some disease states like type 1 diabetes, chronic alcoholism, and schizophrenia, the conversion of ALA to longer-chain fatty acids is reduced, though the reason for this remains unknown. R-ALA, or R-alpha-linolenic acid, is a specific form of alpha-linolenic acid (ALA) that occurs naturally in foods. Unlike ALA, which encompasses both R-ALA and S-ALA forms, R-ALA is the biologically active isomer that is more readily absorbed and utilized by the body.
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Apixaban Overview

  • Apixaban is used help prevent strokes or blood clots in people who have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes) that is not caused by heart valve disease. Apixaban is also used to prevent deep vein thrombosis (DVT; a blood clot, usually in the leg) and pulmonary embolism (PE; a blood clot in the lung) in people who are having hip replacement or knee replacement surgery. Apixaban is also used to treat DVT and PE and may be continued to prevent DVT and PE from happening again after the initial treatment is completed. Apixaban is in a class of medications called factor Xa inhibitors. It works by blocking the action of a certain natural substance that helps blood clots to form.

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Alpha-linolenic Acid (ala) - More Interactions

Alpha-linolenic Acid (ala) interacts with 0 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Dr. Brian Staiger, PharmD

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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