Alpha-linolenic Acid (ala) - Promacta (Eltrombopag) Interaction

Herbal: Alpha-linolenic Acid (ala)
Also Known As: ALA, R-alpha-linolenic acid

Drug: Eltrombopag
Brand names: Promacta, Revolade

Medical Content Editor
Last updated Jun 23, 2024

Interaction Details

There were no interactions found between Eltrombopag and Alpha-linolenic Acid (ala). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.

Still looking for more information about combining Eltrombopag and Alpha-linolenic Acid (ala)? Ask Dr. Brian Staiger about it by contacting him directly.

Alpha-linolenic Acid (ala) Overview

Alpha-linolenic acid (ALA) is an essential omega-3 fatty acid. It is primarily found in vegetable oils like flaxseed, canola, and soybean oils, as well as in red meat, dairy products, margarines, and salad dressings containing vegetable oils. Walnuts and other edible nuts are also significant sources of ALA, along with smaller amounts in green leafy vegetables and chocolate. ALA is present in human breast milk, infant formulas, and intravenous fat emulsions. The body converts ALA into longer and more unsaturated omega-3 fatty acids, such as EPA and DHA, with conversion rates typically low but possibly as high as 30%. However, in some disease states like type 1 diabetes, chronic alcoholism, and schizophrenia, the conversion of ALA to longer-chain fatty acids is reduced, though the reason for this remains unknown. R-ALA, or R-alpha-linolenic acid, is a specific form of alpha-linolenic acid (ALA) that occurs naturally in foods. Unlike ALA, which encompasses both R-ALA and S-ALA forms, R-ALA is the biologically active isomer that is more readily absorbed and utilized by the body.
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Eltrombopag Overview

  • Eltrombopag is used to increase the number of platelets (cells that help the blood clot) to decrease the risk of bleeding in adults and children 1 year of age and older who have chronic immune thrombocytopenia (ITP; an ongoing condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood) and who have not been helped or cannot be treated with other treatments, including medications or surgery to remove the spleen. Eltrombopag is also used to increase the number of platelets in people who have hepatitis C (a viral infection that may damage the liver) so that they can begin and continue treatment with interferon (Peginterferon, Pegintron, others) and ribavirin (Rebetol). Eltrombopag is also used in combination with other medications to treat aplastic anemia (condition in which the body does not make enough new blood cells) in adults and children 2 years of age and older. It is also used to treat aplastic anemia in adults who have not been helped with other medications. Eltrombopag is used to increase the number of platelets enough to decrease the risk of bleeding in people with ITP or aplastic anemia, or to allow treatment with interferon and ribavirin in people with hepatitis C. However it is not used to increase the number of platelets to a normal level. Eltrombopag should not be used to treat people who have low numbers of platelets due to conditions other than ITP, hepatitis C, or aplastic anemia. Eltrombopag is in a class of medications called thrombopoietin receptor agonists. It works by causing the cells in the bone marrow to produce more platelets.

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Alpha-linolenic Acid (ala) - More Interactions

Alpha-linolenic Acid (ala) interacts with 0 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Dr. Brian Staiger, PharmD

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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