Eltrombopag
Generic name: Pronounced as (el trom' boe pag)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 02/15/2019
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
IMPORTANT WARNING
If you have chronic hepatitis C (an ongoing viral infection that may damage the liver) and you take eltrombopag with medications for hepatitis C called interferon (Peginterferon, Pegintron, others) and ribavirin (Copegus, Rebetol, Ribasphere, others), there is an increased risk that you will develop serious liver damage. If you experience any of the following symptoms, call your doctor immediately: yellowing of the skin or eyes, dark urine, excessive tiredness, pain in the upper right part of the stomach, swelling of the stomach area, or confusion.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain laboratory tests before and during your treatment to check your body's response to eltrombopag.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with eltrombopag and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.
Talk to your doctor about the risks of taking eltrombopag.
Why is this medication prescribed?
Eltrombopag is used to increase the number of platelets (cells that help the blood clot) to decrease the risk of bleeding in adults and children 1 year of age and older who have chronic immune thrombocytopenia (ITP; an ongoing condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood) and who have not been helped or cannot be treated with other treatments, including medications or surgery to remove the spleen. Eltrombopag is also used to increase the number of platelets in people who have hepatitis C (a viral infection that may damage the liver) so that they can begin and continue treatment with interferon (Peginterferon, Pegintron, others) and ribavirin (Rebetol). Eltrombopag is also used in combination with other medications to treat aplastic anemia (condition in which the body does not make enough new blood cells) in adults and children 2 years of age and older. It is also used to treat aplastic anemia in adults who have not been helped with other medications. Eltrombopag is used to increase the number of platelets enough to decrease the risk of bleeding in people with ITP or aplastic anemia, or to allow treatment with interferon and ribavirin in people with hepatitis C. However it is not used to increase the number of platelets to a normal level. Eltrombopag should not be used to treat people who have low numbers of platelets due to conditions other than ITP, hepatitis C, or aplastic anemia. Eltrombopag is in a class of medications called thrombopoietin receptor agonists. It works by causing the cells in the bone marrow to produce more platelets.
How should this medicine be used?
Eltrombopag comes as a tablet and as a powder for oral suspension (liquid) to take by mouth. It is usually taken once a day on an empty stomach, at least 1 hour before or 2 hours after eating. Take eltrombopag at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take eltrombopag exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Take eltrombopag at least 2 hours before or 4 hours after you eat or drink foods that contain a lot of calcium, such as dairy products, calcium-fortified juices, cereals, oatmeal, and breads; trout; clams; leafy green vegetables such as spinach and collard greens; and tofu and other soy products. Ask your doctor if you are not sure if a food contains a lot of calcium. You may find it helpful to take eltrombopag close to the beginning or end of your day so that you will be able to eat these foods during most of your waking hours.
Swallow the tablets whole. Do not split, chew, or crush them and mix them into food or liquids.
If you are taking the powder for oral suspension, carefully read the manufacturer's instructions for use that comes with the medication. These instructions describe how to prepare and measure your dose. Mix the powder with cool or cold water before use. Do not mix the powder with hot water. Immediately after preparation, swallow the dose. If it is not taken within 30 minutes or if there is remaining liquid, dispose of the mixture in the trash (do not pour it down the sink).
Do not allow the powder to touch your skin. If you spill the powder on your skin, wash it off immediately with soap and water. Call your doctor if you have a skin reaction or if you have any questions.
Your doctor will probably start you on a low dose of eltrombopag and adjust your dose depending on your response to the medication. At the beginning of your treatment, your doctor will order a blood test to check your platelet level once every week. Your doctor may increase your dose if your platelet level is too low. If your platelet level is too high, your doctor may decrease your dose or may not give you eltrombopag for a time. After your treatment has continued for some time and your doctor has found the dose of eltrombopag that works for you, your platelet level will be checked less often. Your platelet level will also be checked weekly for at least 4 weeks after you stop taking eltrombopag.
If you have chronic ITP, you may receive other medications to treat your condition along with eltrombopag. Your doctor may decrease your dose of these medications if eltrombopag works well for you.
Eltrombopag does not work for everyone. If your platelet level does not increase enough after you have taken eltrombopag for some time, your doctor may tell you to stop taking eltrombopag.
Eltrombopag may help to control your condition but will not cure it. Continue to take eltrombopag even if you feel well. Do not stop taking eltrombopag without talking to your doctor.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking eltrombopag,
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tell your doctor and pharmacist if you are allergic to eltrombopag, any other medications, or any of the ingredients in eltrombopag tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants (blood thinners) such as warfarin (Coumadin, Jantoven); bosentan (Tracleer); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor, in Caduet), fluvastatin (Lescol), pitavastatin (Livalo, Zypitamag), pravastatin (Pravachol), rosuvastatin (Crestor), and simvastatin (Zocor, Flolopid, in Vytorin); ezetimibe (Zetia, in Vytorin); glyburide (Diabeta, Glynase); imatinib (Gleevec); irinotecan (Camptosar, Onivyde); olmesartan (Benicar, in Azor, in Tribenzor); lapatinib (Tykerb); methotrexate (Rasuvo, Trexall, others); mitoxantrone; repaglinide (Prandin): rifampin (Rimactane, Rifadin, in Rifamate, Rifater); sulfasalazine (Azulfidine); topotecan (Hycamtin), and valsartan (Diovan, in Byvalson, in Entresto, in Exforge). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with eltrombopag, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
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if you are taking antacids containing calcium, aluminum, or magnesium (Maalox, Mylanta, Tums) or vitamin or mineral supplements containing calcium, iron, zinc or selenium, take eltrombopag 2 hours before or 4 hours after you take them.
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tell your doctor if you are of East Asian (Chinese, Japanese, Taiwanese, or Korean) descent and if you have or have ever had a cataract (clouding of the lens of the eye that may cause vision problems), blood clots, any condition that increases the risk that you will develop a blood clot, bleeding problems, myelodysplastic syndrome (MDS; a blood disorder that can lead to cancer), or liver disease. Also tell your doctor if you have had surgery to remove your spleen.
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tell your doctor if you are pregnant, or plan to become pregnant. You should not become pregnant during your treatment with eltrombopag. Use effective birth control while you are receiving treatment and for 7 days after your last dose. If you become pregnant while taking eltrombopag, call your doctor.
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tell your doctor if you are breastfeeding. You should not breastfeed while you are taking eltrombopag.
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continue to avoid activities that may cause injury and bleeding during your treatment with eltrombopag. Eltrombopag is given to decrease the risk that you will experience severe bleeding, but there is still a risk that bleeding may occur.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Do not take more than one dose of eltrombopag in one day.
What side effects can this medication cause?
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Eltrombopag may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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back pain
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muscle aches or spasms
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headache
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flu symptoms such as fever, headache, sore throat, cough, tiredness, chills, and body aches
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weakness
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extreme tiredness
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decreased appetite
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pain or swelling in the mouth or throat
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hair loss
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rash
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skin color changes
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skin tingling, itching, or burning
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swelling of the ankles, feet, or lower legs
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toothache (in children)
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Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:
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swelling, pain, tenderness, warmth or redness in one leg
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shortness of breath, coughing up blood, fast heartbeat, fast breathing, pain when breathing deeply
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pain in the chest, arms, back, neck, jaw, or stomach, breaking out in cold sweat, lightheadedness
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slow or difficult speech, sudden weakness or numbness of the face, arm or leg, sudden headache, sudden vision problems, sudden difficulty walking
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stomach pain, nausea, vomiting, diarrhea
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cloudy, blurry vision, or other vision changes
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Eltrombopag may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). If your medication came with a desiccant packet (small packet that contains a substance that absorbs moisture to keep the medication dry), leave the packet in the bottle but be careful not to swallow it.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
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rash
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slowed heartbeat
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excessive tiredness
What OTHER INFORMATION should I know?
Your doctor will order an eye exam before and during your treatment with eltrombopag.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Moxifloxacin | Moxifloxacin The metabolism of Eltrombopag can be decreased when combined with Moxifloxacin. |
Repaglinide | Repaglinide The metabolism of Repaglinide can be decreased when combined with Eltrombopag. |
Montelukast | Montelukast The metabolism of Eltrombopag can be decreased when combined with Montelukast. |
Insulin Glargine (rDNA origin) Injection | Insulin Glargine (rDNA origin) Injection The metabolism of Eltrombopag can be increased when combined with Insulin glargine. |
Leflunomide | Leflunomide The serum concentration of Eltrombopag can be decreased when it is combined with Leflunomide. |
Nevirapine | Nevirapine The metabolism of Eltrombopag can be decreased when combined with Nevirapine. |
Atorvastatin | Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Eltrombopag. |
Aminophylline | Aminophylline The metabolism of Eltrombopag can be decreased when combined with Aminophylline. |
Anagrelide | Anagrelide The metabolism of Eltrombopag can be decreased when combined with Anagrelide. |
Calcium Carbonate | Calcium Carbonate The serum concentration of Eltrombopag can be decreased when it is combined with Calcium carbonate. |
Candesartan | Candesartan The metabolism of Eltrombopag can be decreased when combined with Candesartan. |
Cilostazol | Cilostazol The metabolism of Eltrombopag can be decreased when combined with Cilostazol. |
Clopidogrel | Clopidogrel The metabolism of Eltrombopag can be decreased when combined with Clopidogrel. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The excretion of Erythromycin can be decreased when combined with Eltrombopag. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) Eltrombopag may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level. |
Fenofibrate | Fenofibrate The metabolism of Eltrombopag can be decreased when combined with Fenofibrate. |
Magnesium Gluconate | Magnesium Gluconate Magnesium gluconate can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Magnesium Hydroxide | Magnesium Hydroxide Magnesium hydroxide can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Magnesium Oxide | Magnesium Oxide Magnesium oxide can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Mycophenolate | Mycophenolate The metabolism of Mycophenolic acid can be decreased when combined with Eltrombopag. |
Paregoric | Paregoric The metabolism of Morphine can be decreased when combined with Eltrombopag. |
Ranitidine | Ranitidine The metabolism of Eltrombopag can be decreased when combined with Ranitidine. |
Sumatriptan | Sumatriptan Eltrombopag may decrease the excretion rate of Sumatriptan which could result in a higher serum level. |
Tizanidine | Tizanidine The metabolism of Eltrombopag can be decreased when combined with Tizanidine. |
Zolmitriptan | Zolmitriptan The metabolism of Eltrombopag can be decreased when combined with Zolmitriptan. |
Famotidine Injection | Famotidine Injection The metabolism of Eltrombopag can be decreased when combined with Famotidine. |
Hydromorphone Injection | Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Eltrombopag. |
Interferon Beta-1b Injection | Interferon Beta-1b Injection The metabolism of Eltrombopag can be decreased when combined with Interferon beta-1b. |
Interferon Gamma-1b Injection | Interferon Gamma-1b Injection The metabolism of Eltrombopag can be decreased when combined with Interferon gamma-1b. |
Levofloxacin Injection | Levofloxacin Injection The metabolism of Eltrombopag can be decreased when combined with Levofloxacin. |
Meperidine Injection | Meperidine Injection The metabolism of Eltrombopag can be increased when combined with Meperidine. |
Metoclopramide Injection | Metoclopramide Injection The metabolism of Eltrombopag can be decreased when combined with Metoclopramide. |
Metronidazole Injection | Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Eltrombopag. |
Morphine Injection | Morphine Injection The metabolism of Morphine can be decreased when combined with Eltrombopag. |
Zidovudine Injection | Zidovudine Injection The metabolism of Eltrombopag can be increased when combined with Zidovudine. |
Ondansetron | Ondansetron The metabolism of Eltrombopag can be decreased when combined with Ondansetron. |
Torsemide | Torsemide The metabolism of Torasemide can be decreased when combined with Eltrombopag. |
Olanzapine | Olanzapine The metabolism of Eltrombopag can be decreased when combined with Olanzapine. |
Alosetron | Alosetron The metabolism of Eltrombopag can be decreased when combined with Alosetron. |
Entacapone | Entacapone The metabolism of Entacapone can be decreased when combined with Eltrombopag. |
Hydroxychloroquine | Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Eltrombopag. |
Telmisartan | Telmisartan The metabolism of Telmisartan can be decreased when combined with Eltrombopag. |
Anakinra | Anakinra The metabolism of Eltrombopag can be increased when combined with Anakinra. |
Etanercept Injection | Etanercept Injection The metabolism of Eltrombopag can be increased when combined with Etanercept. |
Modafinil | Modafinil The metabolism of Eltrombopag can be increased when combined with Modafinil. |
Epirubicin | Epirubicin The metabolism of Epirubicin can be decreased when combined with Eltrombopag. |
Zonisamide | Zonisamide The metabolism of Zonisamide can be decreased when combined with Eltrombopag. |
Adalimumab Injection | Adalimumab Injection The metabolism of Eltrombopag can be increased when combined with Adalimumab. |
Ezetimibe | Ezetimibe The metabolism of Ezetimibe can be decreased when combined with Eltrombopag. |
Atazanavir | Atazanavir The metabolism of Eltrombopag can be decreased when combined with Atazanavir. |
Almotriptan | Almotriptan The metabolism of Almotriptan can be decreased when combined with Eltrombopag. |
Rosuvastatin | Rosuvastatin The serum concentration of Rosuvastatin can be increased when it is combined with Eltrombopag. |
Interferon Beta-1a Subcutaneous Injection | Interferon Beta-1a Subcutaneous Injection The metabolism of Eltrombopag can be decreased when combined with Interferon beta-1a. |
Tegaserod | Tegaserod The metabolism of Eltrombopag can be decreased when combined with Tegaserod. |
Frovatriptan | Frovatriptan The metabolism of Eltrombopag can be decreased when combined with Frovatriptan. |
Gemifloxacin | Gemifloxacin The metabolism of Eltrombopag can be decreased when combined with Gemifloxacin. |
Apomorphine Injection | Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Eltrombopag. |
Infliximab Injection | Infliximab Injection The metabolism of Eltrombopag can be increased when combined with Infliximab. |
Rifaximin | Rifaximin The metabolism of Eltrombopag can be increased when combined with Rifaximin. |
Duloxetine | Duloxetine The metabolism of Eltrombopag can be decreased when combined with Duloxetine. |
Bosentan | Bosentan The excretion of Bosentan can be decreased when combined with Eltrombopag. |
Cinacalcet | Cinacalcet The metabolism of Eltrombopag can be decreased when combined with Cinacalcet. |
Erlotinib | Erlotinib The metabolism of Eltrombopag can be decreased when combined with Erlotinib. |
Eszopiclone | Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Eltrombopag. |
Entecavir | Entecavir The metabolism of Eltrombopag can be decreased when combined with Entecavir. |
Peginterferon Alfa-2a Injection | Peginterferon Alfa-2a Injection The metabolism of Eltrombopag can be decreased when combined with Peginterferon alfa-2a. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Eltrombopag can be increased when it is combined with Peginterferon alfa-2b. |
Ramelteon | Ramelteon The metabolism of Eltrombopag can be decreased when combined with Ramelteon. |
Deferasirox | Deferasirox The serum concentration of Eltrombopag can be increased when it is combined with Deferasirox. |
Phenylephrine | Phenylephrine The metabolism of Eltrombopag can be increased when combined with Phenylephrine. |
Tipranavir | Tipranavir The metabolism of Eltrombopag can be increased when combined with Tipranavir. |
Abatacept Injection | Abatacept Injection The metabolism of Eltrombopag can be increased when combined with Abatacept. |
Rasagiline | Rasagiline The metabolism of Eltrombopag can be decreased when combined with Rasagiline. |
Imatinib | Imatinib Eltrombopag may decrease the excretion rate of Imatinib which could result in a higher serum level. |
Sitagliptin | Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Eltrombopag. |
Gefitinib | Gefitinib Eltrombopag may decrease the excretion rate of Gefitinib which could result in a higher serum level. |
Bortezomib | Bortezomib The metabolism of Eltrombopag can be decreased when combined with Bortezomib. |
Clofarabine Injection | Clofarabine Injection Eltrombopag may decrease the excretion rate of Clofarabine which could result in a higher serum level. |
Fulvestrant Injection | Fulvestrant Injection The metabolism of Fulvestrant can be decreased when combined with Eltrombopag. |
Insulin Glulisine (rDNA origin) Injection | Insulin Glulisine (rDNA origin) Injection The metabolism of Eltrombopag can be increased when combined with Insulin glulisine. |
Oxaliplatin Injection | Oxaliplatin Injection Eltrombopag may decrease the excretion rate of Oxaliplatin which could result in a higher serum level. |
Primaquine | Primaquine The metabolism of Eltrombopag can be decreased when combined with Primaquine. |
Pemetrexed Injection | Pemetrexed Injection The metabolism of Eltrombopag can be decreased when combined with Pemetrexed. |
Nabilone | Nabilone The metabolism of Eltrombopag can be decreased when combined with Nabilone. |
Sorafenib | Sorafenib The metabolism of Eltrombopag can be decreased when combined with Sorafenib. |
Lapatinib | Lapatinib The metabolism of Lapatinib can be decreased when combined with Eltrombopag. |
Dasatinib | Dasatinib Eltrombopag may decrease the excretion rate of Dasatinib which could result in a higher serum level. |
Mexiletine | Mexiletine The metabolism of Eltrombopag can be decreased when combined with Mexiletine. |
Armodafinil | Armodafinil The metabolism of Eltrombopag can be increased when combined with Armodafinil. |
Ivermectin | Ivermectin Eltrombopag may decrease the excretion rate of Ivermectin which could result in a higher serum level. |
Nilotinib | Nilotinib The metabolism of Eltrombopag can be decreased when combined with Nilotinib. |
Raltegravir | Raltegravir The metabolism of Raltegravir can be decreased when combined with Eltrombopag. |
Bexarotene | Bexarotene The metabolism of Eltrombopag can be decreased when combined with Bexarotene. |
Mitoxantrone Injection | Mitoxantrone Injection Eltrombopag may decrease the excretion rate of Mitoxantrone which could result in a higher serum level. |
Tretinoin | Tretinoin The metabolism of Tretinoin can be decreased when combined with Eltrombopag. |
Bendamustine Injection | Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Eltrombopag. |
Flecainide | Flecainide The metabolism of Eltrombopag can be decreased when combined with Flecainide. |
Certolizumab Injection | Certolizumab Injection The metabolism of Eltrombopag can be increased when combined with Certolizumab pegol. |
Irinotecan Injection | Irinotecan Injection The risk or severity of neutropenia can be increased when Eltrombopag is combined with Irinotecan. |
Praziquantel | Praziquantel The metabolism of Eltrombopag can be decreased when combined with Praziquantel. |
Silodosin | Silodosin The metabolism of Silodosin can be decreased when combined with Eltrombopag. |
Midazolam | Midazolam The metabolism of Midazolam can be decreased when combined with Eltrombopag. |
Naltrexone Injection | Naltrexone Injection The metabolism of Naltrexone can be decreased when combined with Eltrombopag. |
Betaxolol | Betaxolol The metabolism of Eltrombopag can be decreased when combined with Betaxolol. |
Pralatrexate Injection | Pralatrexate Injection Eltrombopag may decrease the excretion rate of Pralatrexate which could result in a higher serum level. |
Tapentadol | Tapentadol The metabolism of Tapentadol can be decreased when combined with Eltrombopag. |
Topotecan | Topotecan Eltrombopag may decrease the excretion rate of Topotecan which could result in a higher serum level. |
Golimumab Injection | Golimumab Injection The metabolism of Eltrombopag can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The metabolism of Eltrombopag can be decreased when combined with Pazopanib. |
Asenapine | Asenapine The metabolism of Asenapine can be decreased when combined with Eltrombopag. |
Pitavastatin | Pitavastatin Eltrombopag may decrease the excretion rate of Pitavastatin which could result in a higher serum level. |
Albendazole | Albendazole The metabolism of Eltrombopag can be decreased when combined with Albendazole. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Eltrombopag can be increased when combined with Tocilizumab. |
Cabazitaxel Injection | Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Eltrombopag. |
Acetaminophen Injection | Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Eltrombopag. |
Telaprevir | Telaprevir The metabolism of Eltrombopag can be decreased when combined with Glecaprevir. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Eltrombopag. |
Abiraterone | Abiraterone The serum concentration of Eltrombopag can be increased when it is combined with Abiraterone. |
Rivaroxaban | Rivaroxaban Eltrombopag may decrease the excretion rate of Rivaroxaban which could result in a higher serum level. |
Vemurafenib | Vemurafenib The serum concentration of Eltrombopag can be increased when it is combined with Vemurafenib. |
Vismodegib | Vismodegib The metabolism of Eltrombopag can be decreased when combined with Vismodegib. |
Deferiprone | Deferiprone The serum concentration of Deferiprone can be increased when it is combined with Eltrombopag. |
Axitinib | Axitinib The metabolism of Axitinib can be decreased when combined with Eltrombopag. |
Naloxone Injection | Naloxone Injection The metabolism of Naloxone can be decreased when combined with Eltrombopag. |
Ambrisentan | Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Eltrombopag. |
Ezogabine | Ezogabine The metabolism of Tiagabine can be decreased when combined with Eltrombopag. |
Enzalutamide | Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Eltrombopag. |
Regorafenib | Regorafenib The metabolism of Eltrombopag can be decreased when combined with Regorafenib. |
Bosutinib | Bosutinib The metabolism of Eltrombopag can be decreased when combined with Bosutinib. |
Teriflunomide | Teriflunomide The serum concentration of Eltrombopag can be decreased when it is combined with Teriflunomide. |
Cabozantinib (thyroid cancer) | Cabozantinib (thyroid cancer) The metabolism of Eltrombopag can be decreased when combined with Cabozantinib. |
Ponatinib | Ponatinib The metabolism of Ponatinib can be decreased when combined with Eltrombopag. |
Pomalidomide | Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Eltrombopag. |
Apixaban | Apixaban Eltrombopag may decrease the excretion rate of Apixaban which could result in a higher serum level. |
Canagliflozin | Canagliflozin The metabolism of Canagliflozin can be decreased when combined with Eltrombopag. |
Dabrafenib | Dabrafenib The metabolism of Eltrombopag can be decreased when combined with Dabrafenib. |
Trametinib | Trametinib The metabolism of Eltrombopag can be decreased when combined with Trametinib. |
Dolutegravir | Dolutegravir The metabolism of Dolutegravir can be decreased when combined with Eltrombopag. |
Afatinib | Afatinib Eltrombopag may decrease the excretion rate of Afatinib which could result in a higher serum level. |
Levomilnacipran | Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Eltrombopag. |
Vortioxetine | Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Eltrombopag. |
Perampanel | Perampanel The metabolism of Perampanel can be decreased when combined with Eltrombopag. |
Ketorolac Injection | Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Eltrombopag. |
Simeprevir | Simeprevir Eltrombopag may decrease the excretion rate of Simeprevir which could result in a higher serum level. |
Sofosbuvir | Sofosbuvir Eltrombopag may decrease the excretion rate of Sofosbuvir which could result in a higher serum level. |
Dapagliflozin | Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Eltrombopag. |
Iron Sucrose Injection | Iron Sucrose Injection Iron sucrose can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Apremilast | Apremilast The metabolism of Eltrombopag can be increased when combined with Apremilast. |
Siltuximab Injection | Siltuximab Injection The metabolism of Eltrombopag can be increased when combined with Siltuximab. |
Eslicarbazepine | Eslicarbazepine The metabolism of Eslicarbazepine can be decreased when combined with Eltrombopag. |
Iron Dextran Injection | Iron Dextran Injection Iron Dextran can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Belinostat Injection | Belinostat Injection The metabolism of Belinostat can be decreased when combined with Eltrombopag. |
Idelalisib | Idelalisib Eltrombopag may decrease the excretion rate of Idelalisib which could result in a higher serum level. |
Testosterone Injection | Testosterone Injection Eltrombopag may decrease the excretion rate of Testosterone which could result in a higher serum level. |
Peginterferon Beta-1a Injection | Peginterferon Beta-1a Injection The metabolism of Eltrombopag can be decreased when combined with Peginterferon beta-1a. |
Caspofungin Injection | Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Eltrombopag. |
Tasimelteon | Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Eltrombopag. |
Riociguat | Riociguat Eltrombopag may decrease the excretion rate of Riociguat which could result in a higher serum level. |
Pirfenidone | Pirfenidone The metabolism of Eltrombopag can be decreased when combined with Pirfenidone. |
Nintedanib | Nintedanib The metabolism of Nintedanib can be decreased when combined with Eltrombopag. |
Secukinumab Injection | Secukinumab Injection The metabolism of Eltrombopag can be increased when combined with Secukinumab. |
Palbociclib | Palbociclib Eltrombopag may decrease the excretion rate of Palbociclib which could result in a higher serum level. |
Insulin Human Inhalation | Insulin Human Inhalation The metabolism of Eltrombopag can be increased when combined with Insulin human. |
Lenvatinib | Lenvatinib Eltrombopag may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Haloperidol Injection | Haloperidol Injection The metabolism of Haloperidol can be decreased when combined with Eltrombopag. |
Eluxadoline | Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Eltrombopag. |
Insulin Degludec (rDNA Origin) Injection | Insulin Degludec (rDNA Origin) Injection The metabolism of Eltrombopag can be increased when combined with Insulin degludec. |
Cobimetinib | Cobimetinib The excretion of Cobimetinib can be decreased when combined with Eltrombopag. |
Osimertinib | Osimertinib The serum concentration of Eltrombopag can be decreased when it is combined with Osimertinib. |
Rifapentine | Rifapentine The metabolism of Eltrombopag can be increased when combined with Rifapentine. |
Dexamethasone Injection | Dexamethasone Injection The metabolism of Eltrombopag can be increased when combined with Dexamethasone. |
Venetoclax | Venetoclax Eltrombopag may decrease the excretion rate of Venetoclax which could result in a higher serum level. |
Selexipag | Selexipag The metabolism of Selexipag can be decreased when combined with Eltrombopag. |
Obeticholic Acid | Obeticholic Acid The metabolism of Eltrombopag can be decreased when combined with Obeticholic acid. |
Furosemide Injection | Furosemide Injection The metabolism of Furosemide can be decreased when combined with Eltrombopag. |
Rucaparib | Rucaparib The metabolism of Eltrombopag can be decreased when combined with Rucaparib. |
Brigatinib | Brigatinib The metabolism of Brigatinib can be decreased when combined with Eltrombopag. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Eltrombopag can be decreased when combined with Doxepin. |
Safinamide | Safinamide The metabolism of Eltrombopag can be decreased when combined with Safinamide. |
Naldemedine | Naldemedine The metabolism of Naldemedine can be decreased when combined with Eltrombopag. |
Midostaurin | Midostaurin The metabolism of Eltrombopag can be decreased when combined with Midostaurin. |
Enasidenib | Enasidenib The metabolism of Enasidenib can be decreased when combined with Eltrombopag. |
Copanlisib Injection | Copanlisib Injection Eltrombopag may decrease the excretion rate of Copanlisib which could result in a higher serum level. |
Delafloxacin | Delafloxacin The metabolism of Delafloxacin can be decreased when combined with Eltrombopag. |
Abemaciclib | Abemaciclib Eltrombopag may decrease the excretion rate of Abemaciclib which could result in a higher serum level. |
Letermovir | Letermovir The metabolism of Letermovir can be decreased when combined with Eltrombopag. |
Ertugliflozin | Ertugliflozin The metabolism of Eltrombopag can be decreased when combined with Ertugliflozin. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Eltrombopag. |
Apalutamide | Apalutamide The metabolism of Apalutamide can be decreased when combined with Eltrombopag. |
Penicillamine | Penicillamine The excretion of Penicillamine can be decreased when combined with Eltrombopag. |
Fostamatinib | Fostamatinib The metabolism of Eltrombopag can be decreased when combined with Fostamatinib. |
Avatrombopag | Avatrombopag The metabolism of Eltrombopag can be increased when combined with Avatrombopag. |
Lofexidine | Lofexidine The metabolism of Eltrombopag can be decreased when combined with Lofexidine. |
Binimetinib | Binimetinib The metabolism of Binimetinib can be decreased when combined with Eltrombopag. |
Lusutrombopag | Lusutrombopag Eltrombopag may decrease the excretion rate of Lusutrombopag which could result in a higher serum level. |
Elagolix | Elagolix The metabolism of Elagolix can be decreased when combined with Eltrombopag. |
Cannabidiol | Cannabidiol The metabolism of Eltrombopag can be decreased when combined with Cannabidiol. |
Dacomitinib | Dacomitinib The metabolism of Eltrombopag can be decreased when combined with Dacomitinib. |
Duvelisib | Duvelisib Eltrombopag may decrease the excretion rate of Duvelisib which could result in a higher serum level. |
Baloxavir Marboxil | Baloxavir Marboxil The metabolism of Baloxavir marboxil can be decreased when combined with Eltrombopag. |
Stiripentol | Stiripentol The metabolism of Eltrombopag can be decreased when combined with Stiripentol. |
Talazoparib | Talazoparib Eltrombopag may decrease the excretion rate of Talazoparib which could result in a higher serum level. |
Glasdegib | Glasdegib The metabolism of Glasdegib can be decreased when combined with Eltrombopag. |
Lorlatinib | Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Eltrombopag. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Eltrombopag. |
Rifamycin | Rifamycin The metabolism of Eltrombopag can be increased when combined with Rifamycin. |
Magnesium Citrate | Magnesium Citrate Magnesium citrate can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Eltrombopag can be increased when combined with Emapalumab. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic The metabolism of Eltrombopag can be decreased when combined with Acyclovir. |
Alpelisib | Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Eltrombopag. |
Cladribine | Cladribine Eltrombopag may decrease the excretion rate of Cladribine which could result in a higher serum level. |
Darolutamide | Darolutamide Eltrombopag may decrease the excretion rate of Darolutamide which could result in a higher serum level. |
Triclabendazole | Triclabendazole The metabolism of Eltrombopag can be decreased when combined with Triclabendazole. |
Pexidartinib | Pexidartinib The metabolism of Eltrombopag can be decreased when combined with Pexidartinib. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Eltrombopag. |
Pitolisant | Pitolisant The metabolism of Eltrombopag can be increased when combined with Pitolisant. |
Phenytoin Injection | Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Eltrombopag. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Eltrombopag. |
Lumateperone | Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Eltrombopag. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Eltrombopag. |
Calcium Acetate | Calcium Acetate The serum concentration of Eltrombopag can be decreased when it is combined with Calcium acetate. |
Tazemetostat | Tazemetostat Eltrombopag may decrease the excretion rate of Tazemetostat which could result in a higher serum level. |
Bempedoic Acid | Bempedoic Acid The metabolism of Bempedoic acid can be decreased when combined with Eltrombopag. |
Cenobamate | Cenobamate The metabolism of Cenobamate can be decreased when combined with Eltrombopag. |
Ozanimod | Ozanimod Eltrombopag may decrease the excretion rate of Ozanimod which could result in a higher serum level. |
Selumetinib | Selumetinib The metabolism of Selumetinib can be decreased when combined with Eltrombopag. |
Rimegepant | Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Eltrombopag. |
Tucatinib | Tucatinib Eltrombopag may decrease the excretion rate of Tucatinib which could result in a higher serum level. |
Remdesivir Injection | Remdesivir Injection The excretion of Remdesivir can be decreased when combined with Eltrombopag. |
Sacituzumab govitecan-hziy Injection | Sacituzumab govitecan-hziy Injection The serum concentration of Sacituzumab govitecan can be increased when it is combined with Eltrombopag. |
Ripretinib | Ripretinib Eltrombopag may decrease the excretion rate of Ripretinib which could result in a higher serum level. |
Selpercatinib | Selpercatinib The serum concentration of Eltrombopag can be increased when it is combined with Selpercatinib. |
Capmatinib | Capmatinib The metabolism of Eltrombopag can be decreased when combined with Capmatinib. |
Fostemsavir | Fostemsavir Eltrombopag may decrease the excretion rate of Fostemsavir which could result in a higher serum level. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection The excretion of Belantamab mafodotin can be decreased when combined with Eltrombopag. |
Pralsetinib | Pralsetinib Eltrombopag may decrease the excretion rate of Pralsetinib which could result in a higher serum level. |
Opicapone | Opicapone The metabolism of Eltrombopag can be decreased when combined with Opicapone. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Eltrombopag can be decreased when it is combined with Satralizumab. |
Viloxazine | Viloxazine The metabolism of Eltrombopag can be decreased when combined with Viloxazine. |
Theophylline | Theophylline The metabolism of Theophylline can be decreased when combined with Eltrombopag. |
Indomethacin | Indomethacin The metabolism of Eltrombopag can be decreased when combined with Indomethacin. |
Mefenamic Acid | Mefenamic Acid The metabolism of Eltrombopag can be decreased when combined with Mefenamic acid. |
Naproxen | Naproxen The metabolism of Naproxen can be decreased when combined with Eltrombopag. |
Sucralfate | Sucralfate Sucralfate can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Phenobarbital | Phenobarbital The metabolism of Eltrombopag can be increased when combined with Phenobarbital. |
Methotrexate Injection | Methotrexate Injection Eltrombopag may decrease the excretion rate of Methotrexate which could result in a higher serum level. |
Primidone | Primidone The metabolism of Eltrombopag can be increased when combined with Primidone. |
Chlorpromazine | Chlorpromazine The metabolism of Eltrombopag can be decreased when combined with Chlorpromazine. |
Oxazepam | Oxazepam The metabolism of Oxazepam can be decreased when combined with Eltrombopag. |
Carmustine | Carmustine The metabolism of Eltrombopag can be decreased when combined with Carmustine. |
Codeine | Codeine The metabolism of Codeine can be decreased when combined with Eltrombopag. |
Tranylcypromine | Tranylcypromine The metabolism of Eltrombopag can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine The metabolism of Eltrombopag can be decreased when combined with Phenelzine. |
Trifluoperazine | Trifluoperazine The metabolism of Eltrombopag can be decreased when combined with Trifluoperazine. |
Dapsone | Dapsone The metabolism of Dapsone can be decreased when combined with Eltrombopag. |
Sulfadiazine | Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Eltrombopag. |
Methadone | Methadone The metabolism of Methadone can be decreased when combined with Eltrombopag. |
Oxybutynin | Oxybutynin The metabolism of Eltrombopag can be decreased when combined with Oxybutynin. |
Maprotiline | Maprotiline The metabolism of Eltrombopag can be decreased when combined with Maprotiline. |
Ibuprofen | Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Eltrombopag. |
Orphenadrine | Orphenadrine The metabolism of Eltrombopag can be decreased when combined with Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Eltrombopag can be decreased when combined with Perphenazine. |
Azathioprine | Azathioprine The metabolism of Eltrombopag can be decreased when combined with Azathioprine. |
Sulfasalazine | Sulfasalazine Eltrombopag may decrease the excretion rate of Sulfasalazine which could result in a higher serum level. |
Hydrocortisone | Hydrocortisone The metabolism of Eltrombopag can be increased when combined with Hydrocortisone. |
Doxorubicin | Doxorubicin Eltrombopag may decrease the excretion rate of Doxorubicin which could result in a higher serum level. |
Dactinomycin | Dactinomycin Eltrombopag may decrease the excretion rate of Dactinomycin which could result in a higher serum level. |
Carbamazepine | Carbamazepine The metabolism of Eltrombopag can be increased when combined with Carbamazepine. |
Clonidine | Clonidine The metabolism of Eltrombopag can be decreased when combined with Clonidine. |
Prazosin | Prazosin Eltrombopag may decrease the excretion rate of Prazosin which could result in a higher serum level. |
Cimetidine | Cimetidine The metabolism of Eltrombopag can be decreased when combined with Cimetidine. |
Warfarin | Warfarin The metabolism of Eltrombopag can be decreased when combined with Warfarin. |
Loperamide | Loperamide The metabolism of Loperamide can be decreased when combined with Eltrombopag. |
Daunorubicin | Daunorubicin Eltrombopag may decrease the excretion rate of Daunorubicin which could result in a higher serum level. |
Nitrofurantoin | Nitrofurantoin Eltrombopag may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level. |
Griseofulvin | Griseofulvin The metabolism of Eltrombopag can be increased when combined with Griseofulvin. |
Digoxin | Digoxin The excretion of Digoxin can be decreased when combined with Eltrombopag. |
Chloroquine | Chloroquine The metabolism of Chloroquine can be decreased when combined with Eltrombopag. |
Quinine | Quinine The metabolism of Eltrombopag can be decreased when combined with Quinine. |
Triamterene | Triamterene The metabolism of Eltrombopag can be decreased when combined with Triamterene. |
Sulfinpyrazone | Sulfinpyrazone The metabolism of Eltrombopag can be decreased when combined with Sulfinpyrazone. |
Secobarbital | Secobarbital The metabolism of Eltrombopag can be increased when combined with Secobarbital. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Eltrombopag. |
Imipramine | Imipramine The metabolism of Eltrombopag can be decreased when combined with Imipramine. |
Probenecid | Probenecid The metabolism of Eltrombopag can be decreased when combined with Probenecid. |
Quinidine | Quinidine The metabolism of Eltrombopag can be decreased when combined with Quinidine. |
Isoniazid | Isoniazid The metabolism of Eltrombopag can be decreased when combined with Isoniazid. |
Rifampin | Rifampin The metabolism of Eltrombopag can be increased when combined with Rifampicin. |
Disopyramide | Disopyramide The metabolism of Eltrombopag can be decreased when combined with Disopyramide. |
Valproic Acid | Valproic Acid The metabolism of Valproic acid can be decreased when combined with Eltrombopag. |
Tamoxifen | Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Eltrombopag. |
Levothyroxine | Levothyroxine The metabolism of Levothyroxine can be decreased when combined with Eltrombopag. |
Liothyronine | Liothyronine The metabolism of Liothyronine can be decreased when combined with Eltrombopag. |
Methimazole | Methimazole The metabolism of Eltrombopag can be decreased when combined with Methimazole. |
Tolbutamide | Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Eltrombopag. |
Dextromethorphan | Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Eltrombopag. |
Dinoprostone | Dinoprostone The excretion of Dinoprostone can be decreased when combined with Eltrombopag. |
Cyclobenzaprine | Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Eltrombopag. |
Cyproheptadine | Cyproheptadine The metabolism of Cyproheptadine can be decreased when combined with Eltrombopag. |
Chlorzoxazone | Chlorzoxazone The metabolism of Eltrombopag can be decreased when combined with Chlorzoxazone. |
Folic Acid | Folic Acid Eltrombopag may decrease the excretion rate of Folic acid which could result in a higher serum level. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The metabolism of Eltrombopag can be decreased when combined with Propranolol. |
Minoxidil | Minoxidil The metabolism of Minoxidil can be decreased when combined with Eltrombopag. |
Spironolactone | Spironolactone The metabolism of Eltrombopag can be decreased when combined with Spironolactone. |
Allopurinol | Allopurinol Eltrombopag may decrease the excretion rate of Allopurinol which could result in a higher serum level. |
Fluorouracil Injection | Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Eltrombopag. |
Colchicine | Colchicine The metabolism of Eltrombopag can be decreased when combined with Colchicine. |
Dacarbazine | Dacarbazine The metabolism of Eltrombopag can be decreased when combined with Dacarbazine. |
Iron Supplements | Iron Supplements Iron can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Ketoconazole | Ketoconazole The metabolism of Eltrombopag can be decreased when combined with Ketoconazole. |
Vincristine Injection | Vincristine Injection Eltrombopag may decrease the excretion rate of Vincristine which could result in a higher serum level. |
Thiothixene | Thiothixene The metabolism of Eltrombopag can be decreased when combined with Thiothixene. |
Aspirin | Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Eltrombopag. |
Trimethoprim | Trimethoprim The metabolism of Eltrombopag can be decreased when combined with Trimethoprim. |
Diltiazem | Diltiazem The metabolism of Eltrombopag can be decreased when combined with Diltiazem. |
Nifedipine | Nifedipine The metabolism of Eltrombopag can be decreased when combined with Nifedipine. |
Verapamil | Verapamil The metabolism of Verapamil can be decreased when combined with Eltrombopag. |
Piroxicam | Piroxicam The metabolism of Piroxicam can be decreased when combined with Eltrombopag. |
Streptozocin | Streptozocin The metabolism of Eltrombopag can be increased when combined with Streptozocin. |
Etoposide | Etoposide The metabolism of Etoposide can be decreased when combined with Eltrombopag. |
Glyburide | Glyburide Eltrombopag may decrease the excretion rate of Glyburide which could result in a higher serum level. |
Glipizide | Glipizide The metabolism of Glipizide can be decreased when combined with Eltrombopag. |
Nafcillin Injection | Nafcillin Injection The metabolism of Eltrombopag can be increased when combined with Nafcillin. |
Pentoxifylline | Pentoxifylline The metabolism of Eltrombopag can be decreased when combined with Pentoxifylline. |
Labetalol | Labetalol The metabolism of Labetalol can be decreased when combined with Eltrombopag. |
Gemfibrozil | Gemfibrozil The metabolism of Eltrombopag can be decreased when combined with Gemfibrozil. |
Guanabenz | Guanabenz The metabolism of Eltrombopag can be decreased when combined with Guanabenz. |
Ketoprofen | Ketoprofen The metabolism of Ketoprofen can be decreased when combined with Eltrombopag. |
Pimozide | Pimozide The metabolism of Eltrombopag can be decreased when combined with Pimozide. |
Enalapril | Enalapril The excretion of Enalapril can be decreased when combined with Eltrombopag. |
Flurbiprofen | Flurbiprofen The metabolism of Eltrombopag can be decreased when combined with Flurbiprofen. |
Amiodarone | Amiodarone The metabolism of Amiodarone can be decreased when combined with Eltrombopag. |
Lovastatin | Lovastatin The metabolism of Lovastatin can be decreased when combined with Eltrombopag. |
Ciprofloxacin | Ciprofloxacin The metabolism of Eltrombopag can be decreased when combined with Ciprofloxacin. |
Diclofenac | Diclofenac The metabolism of Diclofenac can be decreased when combined with Eltrombopag. |
Fluoxetine | Fluoxetine The metabolism of Eltrombopag can be decreased when combined with Fluoxetine. |
Interferon Alfa-2b Injection | Interferon Alfa-2b Injection The metabolism of Eltrombopag can be decreased when combined with Interferon alfa-2b. |
Clozapine | Clozapine The metabolism of Eltrombopag can be decreased when combined with Clozapine. |
Ofloxacin | Ofloxacin The metabolism of Eltrombopag can be decreased when combined with Ofloxacin. |
Etodolac | Etodolac The metabolism of Etodolac can be decreased when combined with Eltrombopag. |
Felodipine | Felodipine The metabolism of Eltrombopag can be decreased when combined with Felodipine. |
Nabumetone | Nabumetone The metabolism of Eltrombopag can be decreased when combined with Nabumetone. |
Pravastatin | Pravastatin Eltrombopag may decrease the excretion rate of Pravastatin which could result in a higher serum level. |
Simvastatin | Simvastatin The metabolism of Simvastatin can be decreased when combined with Eltrombopag. |
Teniposide Injection | Teniposide Injection Eltrombopag may decrease the excretion rate of Teniposide which could result in a higher serum level. |
Rifabutin | Rifabutin The metabolism of Eltrombopag can be increased when combined with Rifabutin. |
Zolpidem | Zolpidem The metabolism of Eltrombopag can be decreased when combined with Zolpidem. |
Omeprazole | Omeprazole The metabolism of Omeprazole can be decreased when combined with Eltrombopag. |
Cisapride | Cisapride The metabolism of Cisapride can be decreased when combined with Eltrombopag. |
Fluvastatin | Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Eltrombopag. |
Fluvoxamine | Fluvoxamine The metabolism of Eltrombopag can be decreased when combined with Fluvoxamine. |
Lamotrigine | Lamotrigine The metabolism of Eltrombopag can be increased when combined with Lamotrigine. |
Losartan | Losartan The metabolism of Losartan can be decreased when combined with Eltrombopag. |
Tramadol | Tramadol The metabolism of Tramadol can be decreased when combined with Eltrombopag. |
Lansoprazole | Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Eltrombopag. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Eltrombopag. |
Nicardipine | Nicardipine The metabolism of Eltrombopag can be decreased when combined with Nicardipine. |
Ticlopidine | Ticlopidine The metabolism of Eltrombopag can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The metabolism of Eltrombopag can be decreased when combined with Saquinavir. |
Lamivudine | Lamivudine Eltrombopag may decrease the excretion rate of Lamivudine which could result in a higher serum level. |
Riluzole | Riluzole Eltrombopag may decrease the excretion rate of Riluzole which could result in a higher serum level. |
Anastrozole | Anastrozole The metabolism of Eltrombopag can be decreased when combined with Anastrozole. |
Indinavir | Indinavir The metabolism of Eltrombopag can be decreased when combined with Indinavir. |
Ritonavir | Ritonavir The metabolism of Eltrombopag can be decreased when combined with Ritonavir. |
Clomipramine | Clomipramine The metabolism of Eltrombopag can be decreased when combined with Clomipramine. |
Zafirlukast | Zafirlukast The metabolism of Eltrombopag can be decreased when combined with Zafirlukast. |
Mirtazapine | Mirtazapine The metabolism of Eltrombopag can be decreased when combined with Mirtazapine. |
Zileuton | Zileuton The metabolism of Zileuton can be decreased when combined with Eltrombopag. |
Valsartan | Valsartan The excretion of Valsartan can be decreased when combined with Eltrombopag. |
Insulin Lispro Injection | Insulin Lispro Injection The metabolism of Eltrombopag can be increased when combined with Insulin lispro. |
Donepezil | Donepezil Eltrombopag may decrease the excretion rate of Donepezil which could result in a higher serum level. |
Nelfinavir | Nelfinavir The metabolism of Eltrombopag can be increased when combined with Nelfinavir. |
Fexofenadine | Fexofenadine The excretion of Fexofenadine can be decreased when combined with Eltrombopag. |
Loratadine | Loratadine The metabolism of Eltrombopag can be decreased when combined with Loratadine. |
Carvedilol | Carvedilol The metabolism of Carvedilol can be decreased when combined with Eltrombopag. |
Nilutamide | Nilutamide The metabolism of Eltrombopag can be decreased when combined with Nilutamide. |
Flutamide | Flutamide The metabolism of Eltrombopag can be decreased when combined with Flutamide. |
Selegiline | Selegiline The metabolism of Selegiline can be decreased when combined with Eltrombopag. |
Propafenone | Propafenone The metabolism of Eltrombopag can be decreased when combined with Propafenone. |
Raloxifene | Raloxifene The metabolism of Raloxifene can be decreased when combined with Eltrombopag. |
Irbesartan | Irbesartan The metabolism of Eltrombopag can be decreased when combined with Irbesartan. |
Paroxetine | Paroxetine The metabolism of Eltrombopag can be decreased when combined with Paroxetine. |
Citalopram | Citalopram The metabolism of Eltrombopag can be decreased when combined with Citalopram. |
Efavirenz | Efavirenz The metabolism of Eltrombopag can be increased when combined with Efavirenz. |
Abacavir | Abacavir The metabolism of Abacavir can be decreased when combined with Eltrombopag. |
Pioglitazone | Pioglitazone The metabolism of Eltrombopag can be decreased when combined with Pioglitazone. |
Celecoxib | Celecoxib The metabolism of Celecoxib can be decreased when combined with Eltrombopag. |
Rosiglitazone | Rosiglitazone The metabolism of Eltrombopag can be decreased when combined with Rosiglitazone. |
Aluminum Hydroxide | Aluminum Hydroxide Aluminum hydroxide can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Nateglinide | Nateglinide The metabolism of Nateglinide can be decreased when combined with Eltrombopag. |
Rabeprazole | Rabeprazole The metabolism of Eltrombopag can be decreased when combined with Rabeprazole. |
Terbinafine | Terbinafine The metabolism of Terbinafine can be decreased when combined with Eltrombopag. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists