Angelica Archangelica - Tapentadol Interaction
Herbal: Angelica Archangelica
Also Known As: American Angelica, Angelicae Fructus, Angelicae Herba, Angelicae Radix, Angel's Wort, Archangel, Bai Zhi, Canda, Dang Gui (Angelica root), Du Huo, European Angelica, Garden Angelica, Root of the Holy Ghost, Wild Angelica, Wild Parsnip
Drug: Tapentadol
Brand names:
Nucynta, Nucynta ER
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Tapentadol and Angelica Archangelica. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Angelica Archangelica Overview
Angelica archangelica, a perennial herb in the Apiaceae/Umbelliferae family, is characterized by its tall stature, typically reaching heights between 50-250 cm, and large, abundant leaves. Originating from the coastal regions of the North and Baltic Seas, this herb, also known as wild parsnip, has a notable history of use in culinary practices, traditional Chinese medicine, and as a flavoring agent in beverages and liqueurs. With its composition rich in essential oils, phytosterols, caffeic acid derivatives, and flavonoids, along with furanocoumarin compounds such as angelicin and imperatorin, Angelica archangelica is associated with various potential health benefits. These include antioxidant, anti-cancer, anti-fungal, anti-hypertensive, anxiolytic, and cognitive effects. Further research is required to fully elucidate its mechanisms of action and efficacy in treating different conditions. Angelica archangelica has Generally Recognized as Safe (GRAS) status in the United States.
Tapentadol Overview
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Tapentadol tablets are used to treat moderate to severe acute pain (pain that begins suddenly, has a specific cause, and is expected to go away when the cause of the pain is healed). Tapentadol extended-release tablets are used to treat severe neuropathic pain (pain caused by nerve damage) in people who have diabetes. Tapentadol extended-release tablets are only used to treat people who are expected to need medication around-the-clock to relieve pain that cannot be controlled by the use of other pain medications. Tapentadol is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.
Angelica Archangelica - More Interactions
Angelica Archangelica interacts with 333 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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