Interaction Details

There were no interactions found between Pegloticase and Arsenic. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Pegloticase and Arsenic? Ask Dr. Brian Staiger about it by contacting him directly.

Arsenic Overview

Arsenic Arsenic is a trace element naturally present in the diet, with organic forms being generally non-toxic in low amounts, while inorganic forms can be harmful. It is found in foods such as seafood, poultry, grains (especially rice), bread, cereal products, mushrooms, and dairy. The estimated daily intake of organic arsenic is 12-50 mcg, with a suggested requirement of 12-25 mcg daily, while inorganic arsenic intake is estimated at 3.5-10 mcg daily. Arsenic plays a potential role in metabolism, the recycling of methionine, taurine function, and the regulation of gene expression in the body. In traditional Chinese medicine, arsenic has been used to treat various inflammatory disorders, but it is generally only found in homeopathic preparations.
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Pegloticase Overview

  • Pegloticase injection is used alone or in combination with methotrexate (Trexall, Xatmep) and folic acid to treat chronic gout (sudden, severe pain, redness, and swelling in one or more joints caused by abnormally high levels of a substance called uric acid in the blood) in adults who cannot take or did not respond to other medications. Pegloticase injection is in a class of medications called PEGylated uric acid specific enzymes. It works by decreasing the amount of uric acid in the body. Pegloticase injection is used to prevent gout attacks but not to treat them once they occur.

See More Information Regarding Pegloticase Injection

Arsenic - More Interactions

Arsenic interacts with 157 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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