Ascophyllum Nodosum - Amiodarone Interaction
Herbal: Ascophyllum Nodosum
Also Known As: Bladderwrack, Brown Marine Algae, Brown seaweed, Egg Wrack, Hebridean Seaweed, ID-alG, Irish Brown Seaweed, Kelp, Knotted Wrack, Norwegian Kelp, Rockweed, Tasco
Drug: Amiodarone
Brand names:
Pacerone, Cordarone
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 26, 2024
Interaction Details
Amiodarone is classified as belonging to the following category: Amiodarone (Cordarone)
Theoretically, combining Ascophyllum nodosum with amiodarone might cause excessively high iodine levels.
Ascophyllum nodosum contains iodine, although the bioavailability of iodine from Ascophyllum nodosum is lower than that of potassium iodide. Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Interaction Rating
Likelihood of Occurrence
ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
References
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7.
- Combet E, Ma ZF, Cousins F, et al. Low-level seaweed supplementation improves iodine status in iodine-insufficient women. Br J Nutr 2014;112:753-61.
- Simmons-Boyce JL, Purcell SL, Nelson CM, MacKinnon SL. Dietary Ascophyllum nodosum increases urinary excretion of tricarboxylic acid cycle intermediates in male Sprague-dawley rats. J Nutr 2009;139:1487-94.
- Sorge US, Henriksen M, Bastan A, et al. Short communication: Iodine concentrations in serum, milk, and tears after feeding Ascophyllum nodosum to dairy cows-A pilot study. J Dairy Sci 2016;99:8472-6.
Ascophyllum Nodosum Overview
Amiodarone Overview
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Amiodarone is used to treat and prevent certain types of serious, life-threatening ventricular arrhythmias (a certain type of abnormal heart rhythm when other medications did not help or could not be tolerated. Amiodarone is in a class of medications called antiarrhythmics. It works by relaxing overactive heart muscles.
Ascophyllum Nodosum - More Interactions
Ascophyllum Nodosum interacts with 22 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.