Amiodarone
Generic name: Pronounced as (a mee' oh da rone)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 03/15/2017
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
IMPORTANT WARNING
Amiodarone may cause lung damage that can be serious or life-threatening. Tell your doctor if you have or have ever had any type of lung disease or if you have ever developed lung damage or breathing problems while taking amiodarone. If you experience any of the following symptoms, call your doctor immediately: fever, shortness of breath, wheezing, other breathing problems, cough, or coughing or spitting up blood.
Amiodarone may also cause liver damage. Tell your doctor if you have or have ever had liver disease. If you experience any of the following symptoms, call your doctor immediately: nausea, vomiting, dark colored urine, excessive tiredness, yellowing of the skin or eyes, itching, or pain in the upper right part of the stomach.
Amiodarone may cause your arrhythmia (irregular heart rhythm) to worsen or may cause you to develop new arrhythmias. Tell your doctor if you have ever been dizzy or lightheaded or have fainted because your heartbeat was too slow and if you have or have ever had low levels of potassium or magnesium in your blood; heart or thyroid disease; or any problems with your heart rhythm other than the arrhythmia that is being treated. Tell your doctor and pharmacist if you are taking any of the following medications: antifungals such as fluconazole (Diflucan), ketoconazole (Nizoral), and itraconazole (Onmel, Sporanox); azithromycin (Zithromax, Zmax); beta blockers such as propranolol (Hemangeol, Inderal, Innopran); calcium channel blockers such as diltiazem (Cardizem, Cartia, Diltzac, Tiazac, others), and verapamil (Calan, Covera, Verelan, in Tarka); cisapride (Propulsid; not available in the US); clarithromycin (Biaxin); clonidine (Catapres, Kapvay); diuretics ('water pills'); dofetilide (Tikosyn); erythromycin (E.E.S., E-Mycin, Erythrocin); fluoroquinolone antibiotics such as ciprofloxacin (Cipro), levofloxacin (Levaquin), lomefloxacin (not available in the US), moxifloxacin (Avelox), norfloxacin (not available in the US), ofloxacin, and sparfloxacin (not available in the US); other medications for irregular heartbeat such as digoxin (Lanoxin), disopyramide (Norpace), flecainide, ivabradine (Corlanor), phenytoin (Dilantin, Phenytek), procainamide, quinidine (in Nuedexta), and sotalol (Betapace, Sorine, Sotylize); and thioridazine. If you have any of the following symptoms, call your doctor immediately: lightheadedness; fainting; fast, slow, or pounding heartbeat; or feeling that your heart has skipped a beat.
You will probably be hospitalized for one week or longer when you begin your treatment with amiodarone. Your doctor will monitor you carefully during this time and for as long as you continue to take amiodarone. Your doctor will probably start you on a high dose of amiodarone and gradually decrease your dose as the medication begins to work. Your doctor may decrease your dose during your treatment if you develop side effects. Follow your doctor's directions carefully.
Do not stop taking amiodarone without talking to your doctor. You may need to be closely monitored or even hospitalized when you stop taking amiodarone. Amiodarone may remain in your body for some time after you stop taking it, so your doctor will watch you carefully during this time.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests, such as blood tests, X-rays, and electrocardiograms (EKGs, tests that record the electrical activity of the heart) before and during your treatment to be sure that it is safe for you to take amiodarone and to check your body's response to the medication.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with amiodarone and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also obtain the Medication Guide from the FDA website: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.
Talk to your doctor about the risks of taking amiodarone.
Why is this medication prescribed?
Amiodarone is used to treat and prevent certain types of serious, life-threatening ventricular arrhythmias (a certain type of abnormal heart rhythm when other medications did not help or could not be tolerated. Amiodarone is in a class of medications called antiarrhythmics. It works by relaxing overactive heart muscles.
How should this medicine be used?
Amiodarone comes as a tablet to take by mouth. It is usually taken once or twice a day. You may take amiodarone either with or without food, but be sure to take it the same way each time.Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amiodarone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Other uses for this medicine
Amiodarone is also sometimes used to treat other types of arrhythmias. Talk to your doctor about the risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking amiodarone,
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tell your doctor and pharmacist if you are allergic to amiodarone, iodine, any other medications, or any of the ingredients in amiodarone tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: antidepressants ('mood elevators') such as trazodone (Oleptro); anticoagulants ('blood thinners') such as dabigatran (Pradaxa) and warfarin (Coumadin, Jantoven); certain cholesterol lowering medications such as atorvastatin (Lipitor, in Caduet, in Liptruzet), cholestyramine (Prevalite), lovastatin (Altoprev, in Advicor), and simvastatin (Zocor, in Simcor, in Vytorin); cimetidine; clopidogrel (Plavix); cyclosporine (Gengraf, Neoral, Sandimmune); dextromethorphan (a medication in many cough preparations); fentanyl (Actiq, Duragesic, Fentora, others); HIV protease inhibitors such as indinavir (Crixivan) and ritonavir (Norvir, in Kaletra, in Viekira Pak); ledipasvir and sofosbuvir (Harvoni); lithium (Lithobid); loratadine (Claritin); medications for diabetes or seizures; methotrexate (Otrexup, Rasuvo, Trexall); narcotic medications for pain; rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); and sofosbuvir (Solvaldi) with simeprevir (Olysio). Many other medications may interact with amiodarone, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may have to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor what herbal products you are taking, especially St. John's wort.
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tell your doctor if you have diarrhea or have or have ever had any of the conditions mentioned in the IMPORTANT WARNING section or problems with your blood pressure.
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tell your doctor if you are pregnant or plan to become pregnant. Talk to your doctor if you plan to become pregnant during your treatment because amiodarone may remain in your body for some time after you stop taking it. If you become pregnant while taking amiodarone, call your doctor immediately. Amiodarone can cause fetal harm.
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tell your doctor if you are breastfeeding. Do not breastfeed while you are taking amiodarone.
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talk to your doctor about the risks of taking this medication if you are 65 years of age or older. Older adults should not usually take amiodarone because it is not as safe or effective as other medication(s) that can be used to treat the same condition.
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if you are having surgery, including dental surgery or laser eye surgery, tell your doctor or dentist that you are taking amiodarone.
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plan to avoid unnecessary or prolonged exposure to sunlight or sunlamps and to wear protective clothing, sunglasses, and sunscreen. Amiodarone may make your skin sensitive to sunlight. Exposed skin may turn blue-gray and may not return to normal even after you stop taking this medication.
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you should know that amiodarone may cause vision problems including permanent blindness. Be sure to have regular eye exams during your treatment and call your doctor if your eyes become dry, sensitive to light, if you see halos, or have blurred vision or any other problems with your vision.
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you should know that amiodarone may remain in your body for several months after you stop taking it. You may continue to experience side effects of amiodarone during this time. Be sure to tell every health care provider who treats you or prescribes any medication for you during this time that you have recently stopped taking amiodarone.
What special dietary instructions should I follow?
Do not drink grapefruit juice while you are taking this medication.
What should I do if I forget a dose?
Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Amiodarone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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constipation
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loss of appetite
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headache
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decreased sex drive
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difficulty falling asleep or staying asleep
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flushing
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changes in ability to taste and smell
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changes in amount of saliva
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Some side effects can be serious. If you experience any of the following symptoms, or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:
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rash
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weight loss or gain
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restlessness
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weakness
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nervousness
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irritability
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intolerance to heat or cold
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thinning hair
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excessive sweating
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changes in menstrual cycle
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swelling in the front of the neck (goiter)
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swelling of the hands, feet, ankles, or lower legs
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uncontrollable shaking of a part of the body
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decreased concentration
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movements that you cannot control
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poor coordination or trouble walking
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numbness or tingling in the hands, legs, and feet
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muscle weakness
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Amiodarone may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include:
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slow heartbeat
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nausea
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blurred vision
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lightheadedness
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fainting
What OTHER INFORMATION should I know?
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Moxifloxacin | Moxifloxacin The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Amiodarone. |
Repaglinide | Repaglinide The metabolism of Amiodarone can be decreased when combined with Repaglinide. |
Montelukast | Montelukast The metabolism of Amiodarone can be decreased when combined with Montelukast. |
Insulin Glargine (rDNA origin) Injection | Insulin Glargine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Insulin glargine. |
Leflunomide | Leflunomide The metabolism of Leflunomide can be decreased when combined with Amiodarone. |
Delavirdine | Delavirdine The metabolism of Amiodarone can be decreased when combined with Delavirdine. |
Nevirapine | Nevirapine The metabolism of Nevirapine can be decreased when combined with Amiodarone. |
Atorvastatin | Atorvastatin The serum concentration of Atorvastatin can be increased when it is combined with Amiodarone. |
Dolasetron | Dolasetron The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Dolasetron. |
Alendronate | Alendronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Alendronic acid is combined with Amiodarone. |
Aminophylline | Aminophylline The metabolism of Aminophylline can be decreased when combined with Amiodarone. |
Anagrelide | Anagrelide The risk or severity of QTc prolongation can be increased when Anagrelide is combined with Amiodarone. |
Bisacodyl | Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Amiodarone. |
Candesartan | Candesartan The metabolism of Amiodarone can be decreased when combined with Candesartan. |
Cilostazol | Cilostazol The metabolism of Cilostazol can be decreased when combined with Amiodarone. |
Clopidogrel | Clopidogrel The risk or severity of bleeding can be increased when Amiodarone is combined with Clopidogrel. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The metabolism of Amiodarone can be decreased when combined with Erythromycin. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The metabolism of Amiodarone can be decreased when combined with Conjugated estrogens. |
Fenofibrate | Fenofibrate The metabolism of Amiodarone can be decreased when combined with Fenofibrate. |
Guanfacine | Guanfacine The risk or severity of adverse effects can be increased when Amiodarone is combined with Guanfacine. |
Magnesium Gluconate | Magnesium Gluconate The risk or severity of hypotension can be increased when Amiodarone is combined with Magnesium gluconate. |
Magnesium Hydroxide | Magnesium Hydroxide The risk or severity of hypotension can be increased when Amiodarone is combined with Magnesium hydroxide. |
Magnesium Oxide | Magnesium Oxide The risk or severity of hypotension can be increased when Amiodarone is combined with Magnesium oxide. |
Methylergonovine | Methylergonovine The metabolism of Amiodarone can be decreased when combined with Methylergometrine. |
Miglitol | Miglitol The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Miglitol. |
Nafarelin | Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nafarelin is combined with Amiodarone. |
Olsalazine | Olsalazine The risk or severity of hyperkalemia can be increased when Amiodarone is combined with Olsalazine. |
Paregoric | Paregoric The metabolism of Amiodarone can be decreased when combined with Morphine. |
Penbutolol | Penbutolol The therapeutic efficacy of Acebutolol can be increased when used in combination with Amiodarone. |
Polyethylene glycol-electrolyte solution (PEG-ES) | Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Amiodarone. |
Potassium | Potassium Potassium may increase the hyperkalemic activities of Amiodarone. |
Psyllium | Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Amiodarone. |
Ranitidine | Ranitidine The metabolism of Ranitidine can be decreased when combined with Amiodarone. |
Reserpine | Reserpine The serum concentration of Amiodarone can be increased when it is combined with Reserpine. |
Tacrolimus | Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Amiodarone. |
Tizanidine | Tizanidine The metabolism of Amiodarone can be decreased when combined with Tizanidine. |
Triamcinolone | Triamcinolone The metabolism of Amiodarone can be increased when combined with Triamcinolone. |
Zolmitriptan | Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Amiodarone. |
Doxycycline Injection | Doxycycline Injection The metabolism of Amiodarone can be decreased when combined with Doxycycline. |
Famotidine Injection | Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Amiodarone. |
Fluconazole Injection | Fluconazole Injection The metabolism of Amiodarone can be decreased when combined with Fluconazole. |
Foscarnet Injection | Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Amiodarone. |
Hydromorphone Injection | Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Amiodarone. |
Levofloxacin Injection | Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Levofloxacin is combined with Amiodarone. |
Meperidine Injection | Meperidine Injection The metabolism of Amiodarone can be increased when combined with Meperidine. |
Methylprednisolone Injection | Methylprednisolone Injection The metabolism of Amiodarone can be increased when combined with Methylprednisolone. |
Metoclopramide Injection | Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Amiodarone. |
Metronidazole Injection | Metronidazole Injection The metabolism of Amiodarone can be decreased when combined with Metronidazole. |
Morphine Injection | Morphine Injection The metabolism of Amiodarone can be decreased when combined with Morphine. |
Pamidronate Injection | Pamidronate Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pamidronic acid is combined with Amiodarone. |
Zidovudine Injection | Zidovudine Injection The metabolism of Amiodarone can be decreased when combined with Zidovudine. |
Altretamine | Altretamine Amiodarone may increase the orthostatic hypotensive activities of Amphetamine. |
Cyclosporine | Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Amiodarone. |
Ondansetron | Ondansetron The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Ondansetron. |
Enoxaparin Injection | Enoxaparin Injection The risk or severity of hyperkalemia can be increased when Amiodarone is combined with Enoxaparin. |
Granisetron | Granisetron The risk or severity of QTc prolongation can be increased when Granisetron is combined with Amiodarone. |
Torsemide | Torsemide The metabolism of Amiodarone can be decreased when combined with Torasemide. |
Olanzapine | Olanzapine The metabolism of Olanzapine can be decreased when combined with Amiodarone. |
Alosetron | Alosetron The metabolism of Alosetron can be decreased when combined with Amiodarone. |
Dofetilide | Dofetilide The risk or severity of adverse effects can be increased when Dofetilide is combined with Amiodarone. |
Eprosartan | Eprosartan The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Eprosartan is combined with Amiodarone. |
Hydroxychloroquine | Hydroxychloroquine The metabolism of Amiodarone can be decreased when combined with Hydroxychloroquine. |
Meloxicam | Meloxicam The metabolism of Amiodarone can be decreased when combined with Meloxicam. |
Orlistat | Orlistat Orlistat can cause a decrease in the absorption of Amiodarone resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Oxcarbazepine | Oxcarbazepine The metabolism of Amiodarone can be increased when combined with Oxcarbazepine. |
Risedronate | Risedronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Risedronic acid is combined with Amiodarone. |
Sevelamer | Sevelamer The excretion of Amiodarone can be increased when combined with Sevelamer. |
Telmisartan | Telmisartan The risk or severity of adverse effects can be increased when Amiodarone is combined with Telmisartan. |
Anakinra | Anakinra The metabolism of Amiodarone can be increased when combined with Anakinra. |
Desloratadine | Desloratadine The risk or severity of QTc prolongation can be increased when Desloratadine is combined with Amiodarone. |
Linezolid | Linezolid Linezolid may increase the orthostatic hypotensive activities of Amiodarone. |
Rivastigmine | Rivastigmine Rivastigmine may increase the bradycardic activities of Amiodarone. |
Trimipramine | Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Amiodarone. |
Etanercept Injection | Etanercept Injection The metabolism of Amiodarone can be increased when combined with Etanercept. |
Modafinil | Modafinil The metabolism of Amiodarone can be increased when combined with Modafinil. |
Perindopril | Perindopril The risk or severity of hyperkalemia can be increased when Perindopril is combined with Amiodarone. |
Tenofovir | Tenofovir The metabolism of Amiodarone can be decreased when combined with Tenofovir. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate The risk or severity of hyperkalemia can be increased when Amiodarone is combined with Choline magnesium trisalicylate. |
Sirolimus | Sirolimus Amiodarone may increase the immunosuppressive activities of Sirolimus. |
Epinephrine Injection | Epinephrine Injection The metabolism of Amiodarone can be decreased when combined with Epinephrine. |
Eplerenone | Eplerenone The risk or severity of adverse effects can be increased when Amiodarone is combined with Eplerenone. |
Escitalopram | Escitalopram The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Escitalopram. |
Olmesartan | Olmesartan The risk or severity of adverse effects can be increased when Amiodarone is combined with Olmesartan. |
Zonisamide | Zonisamide The risk or severity of adverse effects can be increased when Zonisamide is combined with Amiodarone. |
Adalimumab Injection | Adalimumab Injection The metabolism of Amiodarone can be increased when combined with Adalimumab. |
Aripiprazole | Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Amiodarone. |
Atomoxetine | Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Amiodarone. |
Atazanavir | Atazanavir The serum concentration of Amiodarone can be increased when it is combined with Atazanavir. |
Almotriptan | Almotriptan The metabolism of Amiodarone can be decreased when combined with Almotriptan. |
Eletriptan | Eletriptan The metabolism of Eletriptan can be decreased when combined with Amiodarone. |
Mefloquine | Mefloquine The metabolism of Amiodarone can be decreased when combined with Mefloquine. |
Polyethylene Glycol 3350 | Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Amiodarone. |
Rosuvastatin | Rosuvastatin The metabolism of Rosuvastatin can be increased when combined with Amiodarone. |
Vardenafil | Vardenafil The metabolism of Vardenafil can be decreased when combined with Amiodarone. |
Alfuzosin | Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Amiodarone. |
Aprepitant | Aprepitant The metabolism of Amiodarone can be decreased when combined with Aprepitant. |
Memantine | Memantine The serum concentration of Memantine can be increased when it is combined with Amiodarone. |
Tegaserod | Tegaserod The metabolism of Tegaserod can be decreased when combined with Amiodarone. |
Tadalafil | Tadalafil Amiodarone may increase the hypotensive activities of Tadalafil. |
Fosamprenavir | Fosamprenavir The serum concentration of Amiodarone can be increased when it is combined with Fosamprenavir. |
Frovatriptan | Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Amiodarone. |
Gemifloxacin | Gemifloxacin The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Amiodarone. |
Progesterone | Progesterone The metabolism of Amiodarone can be increased when combined with Progesterone. |
Apomorphine Injection | Apomorphine Injection The metabolism of Amiodarone can be decreased when combined with Apomorphine. |
Infliximab Injection | Infliximab Injection The metabolism of Amiodarone can be increased when combined with Infliximab. |
Protriptyline | Protriptyline The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Protriptyline. |
Rifaximin | Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Amiodarone. |
Duloxetine | Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Amiodarone is combined with Duloxetine. |
Norethindrone | Norethindrone The metabolism of Amiodarone can be decreased when combined with Norethisterone. |
Bosentan | Bosentan The metabolism of Amiodarone can be increased when combined with Bosentan. |
Cinacalcet | Cinacalcet The metabolism of Cinacalcet can be decreased when combined with Amiodarone. |
Erlotinib | Erlotinib The metabolism of Amiodarone can be decreased when combined with Erlotinib. |
Eszopiclone | Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Amiodarone. |
Ganciclovir | Ganciclovir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ganciclovir is combined with Amiodarone. |
Insulin Aspart (rDNA Origin) Injection | Insulin Aspart (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Insulin aspart. |
Solifenacin | Solifenacin The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Solifenacin. |
Voriconazole | Voriconazole The metabolism of Amiodarone can be decreased when combined with Voriconazole. |
Dextroamphetamine | Dextroamphetamine Amiodarone may increase the orthostatic hypotensive activities of Amphetamine. |
Entecavir | Entecavir The metabolism of Entecavir can be decreased when combined with Amiodarone. |
Pramlintide Injection | Pramlintide Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Pramlintide. |
Exenatide Injection | Exenatide Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Exenatide. |
Ibandronate | Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Amiodarone. |
Isocarboxazid | Isocarboxazid Isocarboxazid may increase the orthostatic hypotensive activities of Amiodarone. |
Ramelteon | Ramelteon The metabolism of Ramelteon can be decreased when combined with Amiodarone. |
Darifenacin | Darifenacin The metabolism of Darifenacin can be decreased when combined with Amiodarone. |
Fentanyl | Fentanyl The risk or severity of adverse effects can be increased when Amiodarone is combined with Fentanyl. |
Pregabalin | Pregabalin The risk or severity of adverse effects can be increased when Pregabalin is combined with Amiodarone. |
Deferasirox | Deferasirox The metabolism of Amiodarone can be decreased when combined with Deferasirox. |
Phenylephrine | Phenylephrine The risk or severity of hypertension can be decreased when Phenylephrine is combined with Amiodarone. |
Tipranavir | Tipranavir The metabolism of Amiodarone can be decreased when combined with Tipranavir. |
Felbamate | Felbamate The metabolism of Amiodarone can be increased when combined with Felbamate. |
Insulin Detemir (rDNA Origin) Injection | Insulin Detemir (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Insulin detemir. |
Ranolazine | Ranolazine The serum concentration of Amiodarone can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Amiodarone can be increased when combined with Abatacept. |
Rasagiline | Rasagiline Rasagiline may increase the orthostatic hypotensive activities of Amiodarone. |
Imatinib | Imatinib The metabolism of Amiodarone can be decreased when combined with Imatinib. |
Sitagliptin | Sitagliptin The metabolism of Amiodarone can be decreased when combined with Sitagliptin. |
Varenicline | Varenicline The excretion of Varenicline can be decreased when combined with Amiodarone. |
Gefitinib | Gefitinib The metabolism of Amiodarone can be decreased when combined with Gefitinib. |
Albuterol | Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Amiodarone. |
Paliperidone | Paliperidone The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Paliperidone. |
Bortezomib | Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Amiodarone. |
Clofarabine Injection | Clofarabine Injection The serum concentration of Amiodarone can be increased when it is combined with Clofarabine. |
Insulin Glulisine (rDNA origin) Injection | Insulin Glulisine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Insulin glulisine. |
Lubiprostone | Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Amiodarone. |
Oxaliplatin Injection | Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Oxaliplatin is combined with Amiodarone. |
Posaconazole | Posaconazole The metabolism of Amiodarone can be decreased when combined with Posaconazole. |
Primaquine | Primaquine The metabolism of Amiodarone can be decreased when combined with Primaquine. |
Aliskiren | Aliskiren The risk or severity of hyperkalemia can be increased when Amiodarone is combined with Aliskiren. |
Darunavir | Darunavir The serum concentration of Amiodarone can be increased when it is combined with Darunavir. |
Pemetrexed Injection | Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Amiodarone. |
Dimenhydrinate | Dimenhydrinate The risk or severity of QTc prolongation can be increased when Dimenhydrinate is combined with Amiodarone. |
Lisdexamfetamine | Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Amiodarone. |
Nabilone | Nabilone The metabolism of Amiodarone can be decreased when combined with Nabilone. |
Retapamulin | Retapamulin The metabolism of Retapamulin can be decreased when combined with Amiodarone. |
Vorinostat | Vorinostat The risk or severity of QTc prolongation can be increased when Vorinostat is combined with Amiodarone. |
Sorafenib | Sorafenib The metabolism of Amiodarone can be decreased when combined with Sorafenib. |
Sunitinib | Sunitinib The metabolism of Amiodarone can be decreased when combined with Sunitinib. |
Dronabinol | Dronabinol The metabolism of Dronabinol can be decreased when combined with Amiodarone. |
Lapatinib | Lapatinib The metabolism of Amiodarone can be decreased when combined with Lapatinib. |
Levocetirizine | Levocetirizine The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Amiodarone. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be decreased when combined with Amiodarone. |
Mexiletine | Mexiletine The risk or severity of adverse effects can be increased when Amiodarone is combined with Mexiletine. |
Armodafinil | Armodafinil The metabolism of Amiodarone can be increased when combined with Armodafinil. |
Ivermectin | Ivermectin The metabolism of Amiodarone can be increased when combined with Ivermectin. |
Paclitaxel (with polyoxyethylated castor oil) Injection | Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Amiodarone. |
Temsirolimus | Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Amiodarone. |
Nilotinib | Nilotinib The metabolism of Amiodarone can be decreased when combined with Nilotinib. |
Toremifene | Toremifene The risk or severity of QTc prolongation can be increased when Toremifene is combined with Amiodarone. |
Raltegravir | Raltegravir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amiodarone is combined with Raltegravir. |
Bexarotene | Bexarotene The metabolism of Amiodarone can be increased when combined with Bexarotene. |
Budesonide | Budesonide The metabolism of Amiodarone can be increased when combined with Budesonide. |
Chloramphenicol Injection | Chloramphenicol Injection The metabolism of Amiodarone can be decreased when combined with Chloramphenicol. |
Etravirine | Etravirine The metabolism of Amiodarone can be increased when combined with Etravirine. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Arsenic trioxide. |
Mitoxantrone Injection | Mitoxantrone Injection The metabolism of Mitoxantrone can be decreased when combined with Amiodarone. |
Desvenlafaxine | Desvenlafaxine The metabolism of Amiodarone can be decreased when combined with Desvenlafaxine. |
Cevimeline | Cevimeline The metabolism of Cevimeline can be decreased when combined with Amiodarone. |
Nebivolol | Nebivolol The therapeutic efficacy of Nebivolol can be increased when used in combination with Amiodarone. |
Tretinoin | Tretinoin The metabolism of Amiodarone can be decreased when combined with Tretinoin. |
Bendamustine Injection | Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Amiodarone. |
Pilocarpine | Pilocarpine The metabolism of Amiodarone can be decreased when combined with Pilocarpine. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Amiodarone. |
Certolizumab Injection | Certolizumab Injection The metabolism of Amiodarone can be increased when combined with Certolizumab pegol. |
Ixabepilone Injection | Ixabepilone Injection The metabolism of Amiodarone can be decreased when combined with Ixabepilone. |
Irinotecan Injection | Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Amiodarone. |
Daptomycin Injection | Daptomycin Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Amiodarone. |
Praziquantel | Praziquantel The metabolism of Praziquantel can be decreased when combined with Amiodarone. |
Mitotane | Mitotane The metabolism of Amiodarone can be increased when combined with Mitotane. |
Rufinamide | Rufinamide The metabolism of Amiodarone can be increased when combined with Rufinamide. |
Silodosin | Silodosin The serum concentration of Silodosin can be increased when it is combined with Amiodarone. |
Midazolam | Midazolam The serum concentration of Midazolam can be increased when it is combined with Amiodarone. |
Naltrexone Injection | Naltrexone Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Naltrexone is combined with Amiodarone. |
Eltrombopag | Eltrombopag The metabolism of Amiodarone can be decreased when combined with Eltrombopag. |
Milnacipran | Milnacipran The metabolism of Amiodarone can be decreased when combined with Milnacipran. |
Sodium Phosphate | Sodium Phosphate Amiodarone may increase the hyperkalemic activities of Sodium phosphate, monobasic. |
Fesoterodine | Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Amiodarone. |
Degarelix Injection | Degarelix Injection The risk or severity of QTc prolongation can be increased when Degarelix is combined with Amiodarone. |
Betaxolol | Betaxolol The therapeutic efficacy of Betaxolol can be increased when used in combination with Amiodarone. |
Iloperidone | Iloperidone The metabolism of Iloperidone can be decreased when combined with Amiodarone. |
Prasugrel | Prasugrel The metabolism of Prasugrel can be decreased when combined with Amiodarone. |
Lacosamide | Lacosamide The metabolism of Amiodarone can be decreased when combined with Lacosamide. |
Everolimus | Everolimus The serum concentration of Everolimus can be increased when it is combined with Amiodarone. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Amiodarone. |
Dronedarone | Dronedarone Amiodarone may increase the QTc-prolonging activities of Dronedarone. |
Palonosetron Injection | Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Amiodarone. |
Saxagliptin | Saxagliptin The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Saxagliptin. |
Telavancin Injection | Telavancin Injection The risk or severity of QTc prolongation can be increased when Telavancin is combined with Amiodarone. |
Romidepsin Injection | Romidepsin Injection The serum concentration of Amiodarone can be increased when it is combined with Romidepsin. |
Tapentadol | Tapentadol The metabolism of Tapentadol can be decreased when combined with Amiodarone. |
Topotecan | Topotecan The serum concentration of Topotecan can be increased when it is combined with Amiodarone. |
Golimumab Injection | Golimumab Injection The metabolism of Amiodarone can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Amiodarone. |
Asenapine | Asenapine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Asenapine. |
Pitavastatin | Pitavastatin The metabolism of Pitavastatin can be increased when combined with Amiodarone. |
Albendazole | Albendazole The metabolism of Amiodarone can be decreased when combined with Albendazole. |
Oxymorphone | Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Amiodarone. |
Liraglutide Injection | Liraglutide Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Liraglutide. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Amiodarone can be increased when combined with Tocilizumab. |
Dalfampridine | Dalfampridine The serum concentration of Dalfampridine can be increased when it is combined with Amiodarone. |
Fingolimod | Fingolimod Fingolimod may increase the arrhythmogenic activities of Amiodarone. |
Eribulin Injection | Eribulin Injection The risk or severity of QTc prolongation can be increased when Eribulin is combined with Amiodarone. |
Cabazitaxel Injection | Cabazitaxel Injection The metabolism of Amiodarone can be decreased when combined with Cabazitaxel. |
Lurasidone | Lurasidone The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Amiodarone. |
Acetaminophen Injection | Acetaminophen Injection The metabolism of Amiodarone can be increased when combined with Acetaminophen. |
Vilazodone | Vilazodone The metabolism of Vilazodone can be decreased when combined with Amiodarone. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection The metabolism of Amiodarone can be decreased when combined with Aldesleukin. |
Terbutaline Injection | Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Amiodarone. |
Azilsartan | Azilsartan The risk or severity of hyperkalemia can be increased when Amiodarone is combined with Azilsartan medoxomil. |
Busulfan Injection | Busulfan Injection The metabolism of Amiodarone can be decreased when combined with Busulfan. |
Roflumilast | Roflumilast The metabolism of Amiodarone can be decreased when combined with Roflumilast. |
Linagliptin | Linagliptin The metabolism of Amiodarone can be decreased when combined with Linagliptin. |
Rilpivirine | Rilpivirine The metabolism of Amiodarone can be decreased when combined with Rilpivirine. |
Telaprevir | Telaprevir The metabolism of Glecaprevir can be decreased when combined with Amiodarone. |
Potassium Iodide | Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Amiodarone. |
Cyclophosphamide Injection | Cyclophosphamide Injection The risk or severity of pulmonary toxicity can be increased when Cyclophosphamide is combined with Amiodarone. |
Abiraterone | Abiraterone The metabolism of Amiodarone can be decreased when combined with Abiraterone. |
Triptorelin Injection | Triptorelin Injection The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Amiodarone. |
Rivaroxaban | Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Amiodarone. |
Ticagrelor | Ticagrelor The metabolism of Ticagrelor can be decreased when combined with Amiodarone. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Amiodarone. |
Ruxolitinib | Ruxolitinib Ruxolitinib may increase the bradycardic activities of Amiodarone. |
Vandetanib | Vandetanib The metabolism of Vandetanib can be decreased when combined with Amiodarone. |
Clobazam | Clobazam The metabolism of Clobazam can be increased when combined with Amiodarone. |
Vemurafenib | Vemurafenib The metabolism of Vemurafenib can be decreased when combined with Amiodarone. |
Vismodegib | Vismodegib The metabolism of Amiodarone can be decreased when combined with Vismodegib. |
Ivacaftor | Ivacaftor The metabolism of Amiodarone can be decreased when combined with Ivacaftor. |
Axitinib | Axitinib The metabolism of Amiodarone can be decreased when combined with Axitinib. |
Crizotinib | Crizotinib The metabolism of Amiodarone can be decreased when combined with Crizotinib. |
Cabergoline | Cabergoline The metabolism of Amiodarone can be decreased when combined with Cabergoline. |
Naloxone Injection | Naloxone Injection The metabolism of Amiodarone can be decreased when combined with Naloxone. |
Ambrisentan | Ambrisentan The serum concentration of Amiodarone can be increased when it is combined with Ambrisentan. |
Carfilzomib Injection | Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Amiodarone. |
Iloprost | Iloprost The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Iloprost is combined with Amiodarone. |
Enzalutamide | Enzalutamide The metabolism of Amiodarone can be increased when combined with Enzalutamide. |
Mirabegron | Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Amiodarone. |
Regorafenib | Regorafenib The metabolism of Amiodarone can be decreased when combined with Regorafenib. |
Bosutinib | Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Amiodarone. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The metabolism of Amiodarone can be increased when combined with Corticotropin. |
Linaclotide | Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Amiodarone. |
Teriflunomide | Teriflunomide The metabolism of Amiodarone can be decreased when combined with Teriflunomide. |
Lorcaserin | Lorcaserin The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Mecasermin. |
Cabozantinib (thyroid cancer) | Cabozantinib (thyroid cancer) The metabolism of Amiodarone can be decreased when combined with Cabozantinib. |
Bedaquiline | Bedaquiline The risk or severity of QTc prolongation can be increased when Bedaquiline is combined with Amiodarone. |
Mipomersen Injection | Mipomersen Injection Amiodarone may increase the hepatotoxic activities of Mipomersen. |
Tofacitinib | Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Amiodarone. |
Alogliptin | Alogliptin The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Alogliptin. |
Ponatinib | Ponatinib The metabolism of Amiodarone can be decreased when combined with Ponatinib. |
Pomalidomide | Pomalidomide The serum concentration of Amiodarone can be increased when it is combined with Pomalidomide. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The metabolism of Amiodarone can be decreased when combined with Trastuzumab emtansine. |
Apixaban | Apixaban The metabolism of Amiodarone can be decreased when combined with Apixaban. |
Canagliflozin | Canagliflozin The serum concentration of Amiodarone can be increased when it is combined with Canagliflozin. |
Methazolamide | Methazolamide The risk or severity of adverse effects can be increased when Methazolamide is combined with Amiodarone. |
Dabrafenib | Dabrafenib The metabolism of Amiodarone can be increased when combined with Dabrafenib. |
Ospemifene | Ospemifene The metabolism of Ospemifene can be decreased when combined with Amiodarone. |
Trametinib | Trametinib The metabolism of Amiodarone can be increased when combined with Trametinib. |
Dolutegravir | Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Amiodarone. |
Afatinib | Afatinib The serum concentration of Afatinib can be increased when it is combined with Amiodarone. |
Levomilnacipran | Levomilnacipran The metabolism of Amiodarone can be decreased when combined with Levomilnacipran. |
Vortioxetine | Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Amiodarone. |
Perampanel | Perampanel The metabolism of Amiodarone can be increased when combined with Perampanel. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Amiodarone. |
Lomitapide | Lomitapide The metabolism of Amiodarone can be decreased when combined with Lomitapide. |
Avanafil | Avanafil The risk or severity of hypotension can be increased when Avanafil is combined with Amiodarone. |
Ketorolac Injection | Ketorolac Injection The metabolism of Amiodarone can be decreased when combined with Ketorolac. |
Obinutuzumab Injection | Obinutuzumab Injection The risk or severity of adverse effects can be increased when Amiodarone is combined with Obinutuzumab. |
Simeprevir | Simeprevir The metabolism of Amiodarone can be decreased when combined with Simeprevir. |
Sofosbuvir | Sofosbuvir Sofosbuvir may increase the bradycardic activities of Amiodarone. |
Dapagliflozin | Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Amiodarone. |
Apremilast | Apremilast The metabolism of Amiodarone can be increased when combined with Apremilast. |
Ceritinib | Ceritinib Amiodarone may increase the bradycardic activities of Ceritinib. |
Siltuximab Injection | Siltuximab Injection The metabolism of Amiodarone can be increased when combined with Siltuximab. |
Albiglutide Injection | Albiglutide Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Albiglutide. |
Eslicarbazepine | Eslicarbazepine The metabolism of Amiodarone can be increased when combined with Eslicarbazepine. |
Belinostat Injection | Belinostat Injection The serum concentration of Belinostat can be increased when it is combined with Amiodarone. |
Idelalisib | Idelalisib The metabolism of Idelalisib can be decreased when combined with Amiodarone. |
Testosterone Injection | Testosterone Injection The metabolism of Amiodarone can be increased when combined with Testosterone. |
Oritavancin Injection | Oritavancin Injection The metabolism of Amiodarone can be increased when combined with Oritavancin. |
Empagliflozin | Empagliflozin The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Empagliflozin. |
Vorapaxar | Vorapaxar The metabolism of Amiodarone can be decreased when combined with Vorapaxar. |
Hydrocodone | Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Amiodarone. |
Suvorexant | Suvorexant The metabolism of Amiodarone can be decreased when combined with Suvorexant. |
Dulaglutide Injection | Dulaglutide Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Dulaglutide. |
Edoxaban | Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Amiodarone. |
Olaparib | Olaparib The metabolism of Amiodarone can be decreased when combined with Olaparib. |
Methamphetamine | Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Amiodarone. |
Tasimelteon | Tasimelteon The metabolism of Amiodarone can be decreased when combined with Tasimelteon. |
Riociguat | Riociguat The metabolism of Amiodarone can be decreased when combined with Riociguat. |
Lanreotide Injection | Lanreotide Injection The metabolism of Amiodarone can be decreased when combined with Lanreotide. |
Pirfenidone | Pirfenidone The metabolism of Amiodarone can be decreased when combined with Pirfenidone. |
Nintedanib | Nintedanib The metabolism of Amiodarone can be decreased when combined with Nintedanib. |
Secukinumab Injection | Secukinumab Injection The metabolism of Amiodarone can be increased when combined with Secukinumab. |
Risperidone Injection | Risperidone Injection Amiodarone may increase the hypotensive activities of Risperidone. |
Palbociclib | Palbociclib The metabolism of Amiodarone can be decreased when combined with Palbociclib. |
Insulin Human Inhalation | Insulin Human Inhalation The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Insulin human. |
Lenvatinib | Lenvatinib The metabolism of Lenvatinib can be increased when combined with Amiodarone. |
Naloxegol | Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Amiodarone. |
Panobinostat | Panobinostat The serum concentration of Panobinostat can be increased when it is combined with Amiodarone. |
Dinutuximab Injection | Dinutuximab Injection The risk or severity of adverse effects can be increased when Amiodarone is combined with Dinutuximab. |
Haloperidol Injection | Haloperidol Injection The risk or severity of QTc prolongation can be increased when Haloperidol is combined with Amiodarone. |
Ivabradine | Ivabradine Ivabradine may increase the bradycardic activities of Amiodarone. |
Amiloride | Amiloride The risk or severity of hyperkalemia can be increased when Amiloride is combined with Amiodarone. |
Isavuconazonium Injection | Isavuconazonium Injection The metabolism of Amiodarone can be increased when combined with Isavuconazonium. |
Macitentan | Macitentan Amiodarone may increase the hypotensive activities of Macitentan. |
Sonidegib | Sonidegib The metabolism of Sonidegib can be decreased when combined with Amiodarone. |
Prednisolone | Prednisolone The metabolism of Amiodarone can be increased when combined with Prednisolone. |
Daclatasvir | Daclatasvir Daclatasvir may increase the bradycardic activities of Amiodarone. |
Brexpiprazole | Brexpiprazole The risk or severity of hypotension can be increased when Amiodarone is combined with Brexpiprazole. |
Ziprasidone Injection | Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Ziprasidone is combined with Amiodarone. |
Cariprazine | Cariprazine The metabolism of Cariprazine can be decreased when combined with Amiodarone. |
Insulin Degludec (rDNA Origin) Injection | Insulin Degludec (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Insulin degludec. |
Cobimetinib | Cobimetinib The serum concentration of Amiodarone can be increased when it is combined with Cobimetinib. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Amiodarone. |
Osimertinib | Osimertinib The metabolism of Osimertinib can be increased when combined with Amiodarone. |
Alectinib | Alectinib The metabolism of Alectinib can be decreased when combined with Amiodarone. |
Ixazomib | Ixazomib The metabolism of Ixazomib can be decreased when combined with Amiodarone. |
Rifapentine | Rifapentine The metabolism of Amiodarone can be increased when combined with Rifapentine. |
Lesinurad | Lesinurad The metabolism of Lesinurad can be increased when combined with Amiodarone. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection Amiodarone may decrease the nephrotoxic activities of Amphotericin B. |
Dexamethasone Injection | Dexamethasone Injection The metabolism of Amiodarone can be decreased when combined with Dexamethasone. |
Brivaracetam Injection | Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Amiodarone. |
Venetoclax | Venetoclax The metabolism of Amiodarone can be decreased when combined with Venetoclax. |
Cobicistat | Cobicistat The metabolism of Amiodarone can be decreased when combined with Cobicistat. |
Midodrine | Midodrine Midodrine may increase the bradycardic activities of Amiodarone. |
Selexipag | Selexipag The metabolism of Amiodarone can be decreased when combined with Selexipag. |
Diphenhydramine Injection | Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Amiodarone. |
Furosemide Injection | Furosemide Injection The risk or severity of adverse effects can be increased when Furosemide is combined with Amiodarone. |
Rucaparib | Rucaparib The metabolism of Rucaparib can be decreased when combined with Amiodarone. |
Lixisenatide Injection | Lixisenatide Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Lixisenatide. |
Ribociclib | Ribociclib The metabolism of Amiodarone can be decreased when combined with Ribociclib. |
Brigatinib | Brigatinib The metabolism of Amiodarone can be increased when combined with Brigatinib. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Amiodarone. |
Plecanatide | Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Amiodarone. |
Deutetrabenazine | Deutetrabenazine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Deutetrabenazine. |
Valbenazine | Valbenazine The metabolism of Valbenazine can be decreased when combined with Amiodarone. |
Deflazacort | Deflazacort The metabolism of Amiodarone can be increased when combined with Deflazacort. |
Safinamide | Safinamide Safinamide may increase the orthostatic hypotensive activities of Amiodarone. |
Sarilumab Injection | Sarilumab Injection The metabolism of Amiodarone can be increased when combined with Sarilumab. |
Midostaurin | Midostaurin The metabolism of Amiodarone can be increased when combined with Midostaurin. |
Neratinib | Neratinib The metabolism of Neratinib can be decreased when combined with Amiodarone. |
Enasidenib | Enasidenib The metabolism of Amiodarone can be increased when combined with Enasidenib. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Amiodarone. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Amiodarone can be increased when combined with Fosaprepitant. |
Copanlisib Injection | Copanlisib Injection The serum concentration of Amiodarone can be increased when it is combined with Copanlisib. |
Delafloxacin | Delafloxacin The risk or severity of QTc prolongation can be increased when Delafloxacin is combined with Amiodarone. |
Abemaciclib | Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Amiodarone. |
Betrixaban | Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Amiodarone. |
Acalabrutinib | Acalabrutinib The metabolism of Amiodarone can be decreased when combined with Acalabrutinib. |
Letermovir | Letermovir The metabolism of Amiodarone can be decreased when combined with Letermovir. |
Semaglutide Injection | Semaglutide Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Semaglutide. |
Tetrabenazine | Tetrabenazine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Tetrabenazine. |
Ertugliflozin | Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Amiodarone. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Amiodarone can be decreased when combined with Buprenorphine. |
Apalutamide | Apalutamide The metabolism of Amiodarone can be increased when combined with Apalutamide. |
Penicillamine | Penicillamine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Penicillamine is combined with Amiodarone. |
Fostamatinib | Fostamatinib The metabolism of Amiodarone can be decreased when combined with Fostamatinib. |
Avatrombopag | Avatrombopag The metabolism of Amiodarone can be increased when combined with Avatrombopag. |
Baricitinib | Baricitinib The metabolism of Amiodarone can be decreased when combined with Baricitinib. |
Lofexidine | Lofexidine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Lofexidine. |
Eliglustat | Eliglustat The metabolism of Eliglustat can be decreased when combined with Amiodarone. |
Encorafenib | Encorafenib The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Encorafenib. |
Binimetinib | Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Amiodarone. |
Ivosidenib | Ivosidenib The metabolism of Amiodarone can be increased when combined with Ivosidenib. |
Lusutrombopag | Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Amiodarone. |
Elagolix | Elagolix The metabolism of Amiodarone can be decreased when combined with Elagolix. |
Tafenoquine | Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Amiodarone. |
Cannabidiol | Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Amiodarone. |
Dacomitinib | Dacomitinib The serum concentration of Dacomitinib can be increased when it is combined with Amiodarone. |
Duvelisib | Duvelisib The metabolism of Amiodarone can be decreased when combined with Duvelisib. |
Omadacycline | Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Amiodarone. |
Stiripentol | Stiripentol The metabolism of Amiodarone can be decreased when combined with Stiripentol. |
Talazoparib | Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Amiodarone. |
Gilteritinib | Gilteritinib The risk or severity of QTc prolongation can be increased when Gilteritinib is combined with Amiodarone. |
Glasdegib | Glasdegib The metabolism of Amiodarone can be decreased when combined with Glasdegib. |
Lorlatinib | Lorlatinib The metabolism of Amiodarone can be decreased when combined with Lorlatinib. |
Larotrectinib | Larotrectinib The serum concentration of Amiodarone can be increased when it is combined with Larotrectinib. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Amiodarone can be increased when combined with Paclitaxel. |
Rifamycin | Rifamycin The metabolism of Amiodarone can be increased when combined with Rifamycin. |
Prucalopride | Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Amiodarone. |
Magnesium Citrate | Magnesium Citrate The risk or severity of hypotension can be increased when Amiodarone is combined with Magnesium citrate. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Amiodarone can be increased when combined with Emapalumab. |
Siponimod | Siponimod The risk or severity of adverse effects can be increased when Amiodarone is combined with Siponimod. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Amiodarone. |
Erdafitinib | Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Amiodarone. |
Alpelisib | Alpelisib The metabolism of Amiodarone can be increased when combined with Alpelisib. |
Cladribine | Cladribine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cladribine is combined with Amiodarone. |
Solriamfetol | Solriamfetol The serum concentration of Solriamfetol can be increased when it is combined with Amiodarone. |
Darolutamide | Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Amiodarone. |
Triclabendazole | Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Amiodarone. |
Entrectinib | Entrectinib The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Entrectinib. |
Pexidartinib | Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Amiodarone. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Amiodarone. |
Pitolisant | Pitolisant The serum concentration of Amiodarone can be decreased when it is combined with Pitolisant. |
Fedratinib | Fedratinib The serum concentration of Fedratinib can be increased when it is combined with Amiodarone. |
Lefamulin | Lefamulin Amiodarone may increase the QTc-prolonging activities of Lefamulin. |
Phenytoin Injection | Phenytoin Injection The serum concentration of Amiodarone can be decreased when it is combined with Phenytoin. |
Fosphenytoin Injection | Fosphenytoin Injection The serum concentration of Amiodarone can be decreased when it is combined with Fosphenytoin. |
Enfortumab vedotin-ejfv Injection | Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Amiodarone. |
Zanubrutinib | Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Amiodarone. |
Voxelotor | Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Amiodarone. |
Avapritinib | Avapritinib The metabolism of Avapritinib can be decreased when combined with Amiodarone. |
Lasmiditan | Lasmiditan Lasmiditan may increase the bradycardic activities of Amiodarone. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Amiodarone. |
Calcium Acetate | Calcium Acetate The therapeutic efficacy of Amiodarone can be decreased when used in combination with Calcium acetate. |
Tazemetostat | Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Amiodarone. |
Cenobamate | Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Amiodarone. |
Ozanimod | Ozanimod The metabolism of Ozanimod can be decreased when combined with Amiodarone. |
Selumetinib | Selumetinib The metabolism of Selumetinib can be decreased when combined with Amiodarone. |
Rimegepant | Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Amiodarone. |
Tucatinib | Tucatinib The metabolism of Tucatinib can be decreased when combined with Amiodarone. |
Remdesivir Injection | Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Amiodarone. |
Ripretinib | Ripretinib The serum concentration of Ripretinib can be increased when it is combined with Amiodarone. |
Selpercatinib | Selpercatinib The serum concentration of Amiodarone can be increased when it is combined with Selpercatinib. |
Capmatinib | Capmatinib The serum concentration of Capmatinib can be increased when it is combined with Amiodarone. |
Lemborexant | Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Amiodarone. |
Fostemsavir | Fostemsavir The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Amiodarone. |
Octreotide | Octreotide The serum concentration of the active metabolites of Amiodarone can be increased when Amiodarone is used in combination with Octreotide. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Amiodarone. |
Pralsetinib | Pralsetinib The serum concentration of Pralsetinib can be increased when it is combined with Amiodarone. |
Opicapone | Opicapone The metabolism of Amiodarone can be decreased when combined with Opicapone. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Amiodarone can be decreased when it is combined with Satralizumab. |
Relugolix | Relugolix The serum concentration of Relugolix can be increased when it is combined with Amiodarone. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Amiodarone can be decreased when combined with Drospirenone. |
Vitamin E (Alpha-Tocopherol) | Vitamin E (Alpha-Tocopherol) The metabolism of Vitamin E can be increased when combined with Amiodarone. |
Theophylline | Theophylline The metabolism of Amiodarone can be decreased when combined with Theophylline. |
Fenoprofen | Fenoprofen The risk or severity of hyperkalemia can be increased when Fenoprofen is combined with Amiodarone. |
Indomethacin | Indomethacin The metabolism of Amiodarone can be decreased when combined with Indomethacin. |
Mefenamic Acid | Mefenamic Acid The metabolism of Amiodarone can be decreased when combined with Mefenamic acid. |
Naproxen | Naproxen The metabolism of Amiodarone can be decreased when combined with Naproxen. |
Tolmetin | Tolmetin The risk or severity of hyperkalemia can be increased when Tolmetin is combined with Amiodarone. |
Sulindac | Sulindac The risk or severity of hyperkalemia can be increased when Sulindac is combined with Amiodarone. |
Trazodone | Trazodone Trazodone may increase the QTc-prolonging activities of Amiodarone. |
Isotretinoin | Isotretinoin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isotretinoin is combined with Amiodarone. |
Phenobarbital | Phenobarbital The metabolism of Phenobarbital can be increased when combined with Amiodarone. |
Methotrexate Injection | Methotrexate Injection The metabolism of Amiodarone can be decreased when combined with Methotrexate. |
Primidone | Primidone The metabolism of Amiodarone can be increased when combined with Primidone. |
Methsuximide | Methsuximide The risk or severity of adverse effects can be increased when Methsuximide is combined with Amiodarone. |
Chlorpromazine | Chlorpromazine The metabolism of Amiodarone can be increased when combined with Chlorpromazine. |
Diazepam | Diazepam The metabolism of Amiodarone can be decreased when combined with Diazepam. |
Flurazepam | Flurazepam The metabolism of Flurazepam can be decreased when combined with Amiodarone. |
Lorazepam | Lorazepam The metabolism of Amiodarone can be decreased when combined with Lorazepam. |
Phenoxybenzamine | Phenoxybenzamine The risk or severity of hypotension can be increased when Phenoxybenzamine is combined with Amiodarone. |
Carmustine | Carmustine The metabolism of Carmustine can be decreased when combined with Amiodarone. |
Amantadine | Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Amiodarone. |
Codeine | Codeine The metabolism of Codeine can be decreased when combined with Amiodarone. |
Bromocriptine | Bromocriptine The metabolism of Bromocriptine can be decreased when combined with Amiodarone. |
Tranylcypromine | Tranylcypromine The metabolism of Amiodarone can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine The metabolism of Amiodarone can be decreased when combined with Phenelzine. |
Procarbazine | Procarbazine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amiodarone is combined with Procarbazine. |
Tetracycline | Tetracycline The metabolism of Amiodarone can be decreased when combined with Tetracycline. |
Minocycline | Minocycline The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Minocycline is combined with Amiodarone. |
Prochlorperazine | Prochlorperazine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Prochlorperazine. |
Thioridazine | Thioridazine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Thioridazine. |
Trifluoperazine | Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Amiodarone. |
Dapsone | Dapsone The metabolism of Amiodarone can be decreased when combined with Dapsone. |
Sulfadiazine | Sulfadiazine The metabolism of Amiodarone can be decreased when combined with Sulfadiazine. |
Oxycodone | Oxycodone The metabolism of Oxycodone can be decreased when combined with Amiodarone. |
Methadone | Methadone The metabolism of Methadone can be increased when combined with Amiodarone. |
Oxybutynin | Oxybutynin The metabolism of Amiodarone can be decreased when combined with Oxybutynin. |
Benztropine | Benztropine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Benzatropine. |
Colestipol | Colestipol The excretion of Amiodarone can be increased when combined with Colestipol. |
Maprotiline | Maprotiline The metabolism of Maprotiline can be decreased when combined with Amiodarone. |
Ibuprofen | Ibuprofen The metabolism of Amiodarone can be decreased when combined with Ibuprofen. |
Orphenadrine | Orphenadrine The metabolism of Amiodarone can be decreased when combined with Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Perphenazine can be decreased when combined with Amiodarone. |
Azathioprine | Azathioprine The metabolism of Azathioprine can be decreased when combined with Amiodarone. |
Phentermine | Phentermine The metabolism of Amiodarone can be decreased when combined with Phentermine. |
Amoxapine | Amoxapine The metabolism of Amoxapine can be decreased when combined with Amiodarone. |
Sulfasalazine | Sulfasalazine The risk or severity of hyperkalemia can be increased when Sulfasalazine is combined with Amiodarone. |
Hydrocortisone | Hydrocortisone The metabolism of Amiodarone can be increased when combined with Hydrocortisone. |
Doxorubicin | Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Amiodarone. |
Cytarabine | Cytarabine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cytarabine is combined with Amiodarone. |
Dactinomycin | Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Amiodarone. |
Carbamazepine | Carbamazepine The metabolism of Amiodarone can be increased when combined with Carbamazepine. |
Methyldopa | Methyldopa The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Methyldopa is combined with Amiodarone. |
Clonidine | Clonidine Clonidine may increase the atrioventricular blocking (AV block) activities of Amiodarone. |
Prazosin | Prazosin The serum concentration of Prazosin can be increased when it is combined with Amiodarone. |
Hydralazine | Hydralazine The metabolism of Amiodarone can be decreased when combined with Hydralazine. |
Cimetidine | Cimetidine The serum concentration of Amiodarone can be increased when it is combined with Cimetidine. |
Warfarin | Warfarin The risk or severity of bleeding can be increased when Amiodarone is combined with Warfarin. |
Loperamide | Loperamide The risk or severity of adverse effects can be increased when Loperamide is combined with Amiodarone. |
Promethazine | Promethazine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Promethazine. |
Meclofenamate | Meclofenamate The risk or severity of hyperkalemia can be increased when Meclofenamic acid is combined with Amiodarone. |
Daunorubicin | Daunorubicin The metabolism of Amiodarone can be decreased when combined with Daunorubicin. |
Nitrofurantoin | Nitrofurantoin The risk or severity of hyperkalemia can be increased when Nitrofurantoin is combined with Amiodarone. |
Griseofulvin | Griseofulvin The metabolism of Amiodarone can be increased when combined with Griseofulvin. |
Digoxin | Digoxin The serum concentration of Digoxin can be increased when it is combined with Amiodarone. |
Chloroquine | Chloroquine The metabolism of Amiodarone can be decreased when combined with Chloroquine. |
Quinine | Quinine The metabolism of Quinine can be increased when combined with Amiodarone. |
Ethosuximide | Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Amiodarone. |
Calcitriol | Calcitriol The metabolism of Amiodarone can be increased when combined with Calcitriol. |
Triamterene | Triamterene The metabolism of Triamterene can be decreased when combined with Amiodarone. |
Lactulose | Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Amiodarone. |
Sulfinpyrazone | Sulfinpyrazone The metabolism of Amiodarone can be increased when combined with Sulfinpyrazone. |
Chlorothiazide | Chlorothiazide The risk or severity of adverse effects can be increased when Amiodarone is combined with Chlorothiazide. |
Chlorthalidone | Chlorthalidone The risk or severity of adverse effects can be increased when Amiodarone is combined with Chlorthalidone. |
Metolazone | Metolazone The risk or severity of adverse effects can be increased when Amiodarone is combined with Metolazone. |
Isosorbide | Isosorbide Amiodarone may increase the vasodilatory activities of Isosorbide. |
Clindamycin Injection | Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Amiodarone. |
Secobarbital | Secobarbital The metabolism of Amiodarone can be increased when combined with Secobarbital. |
Desipramine | Desipramine The metabolism of Desipramine can be decreased when combined with Amiodarone. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Amiodarone. |
Imipramine | Imipramine The serum concentration of Imipramine can be increased when it is combined with Amiodarone. |
Probenecid | Probenecid The metabolism of Amiodarone can be increased when combined with Probenecid. |
Quinidine | Quinidine The serum concentration of Quinidine can be increased when it is combined with Amiodarone. |
Procainamide | Procainamide The serum concentration of Procainamide can be increased when it is combined with Amiodarone. |
Isoniazid | Isoniazid The metabolism of Amiodarone can be decreased when combined with Isoniazid. |
Rifampin | Rifampin The serum concentration of Amiodarone can be decreased when it is combined with Rifampicin. |
Disopyramide | Disopyramide Amiodarone may increase the QTc-prolonging activities of Disopyramide. |
Valproic Acid | Valproic Acid The metabolism of Amiodarone can be decreased when combined with Valproic acid. |
Tamoxifen | Tamoxifen The metabolism of Amiodarone can be increased when combined with Tamoxifen. |
Butabarbital | Butabarbital Butabarbital may increase the hypotensive activities of Amiodarone. |
Levothyroxine | Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Amiodarone. |
Liothyronine | Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Amiodarone. |
Methimazole | Methimazole The therapeutic efficacy of Methimazole can be decreased when used in combination with Amiodarone. |
Propylthiouracil | Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Amiodarone. |
Chlorpropamide | Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Amiodarone. |
Tolbutamide | Tolbutamide The metabolism of Amiodarone can be decreased when combined with Tolbutamide. |
Tolazamide | Tolazamide The metabolism of Tolazamide can be decreased when combined with Amiodarone. |
Dextromethorphan | Dextromethorphan The serum concentration of Amiodarone can be increased when it is combined with Dextromethorphan. |
Cyclobenzaprine | Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Amiodarone. |
Niacin | Niacin The metabolism of Amiodarone can be decreased when combined with Niacin. |
Baclofen | Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Amiodarone. |
Doxylamine | Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Amiodarone. |
Cyproheptadine | Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Amiodarone. |
Clemastine | Clemastine The risk or severity of QTc prolongation can be increased when Clemastine is combined with Amiodarone. |
Chlorpheniramine | Chlorpheniramine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Chlorpheniramine. |
Brompheniramine | Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Amiodarone. |
Meclizine | Meclizine The metabolism of Meclizine can be decreased when combined with Amiodarone. |
Methyclothiazide | Methyclothiazide The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Amiodarone. |
Hydrochlorothiazide | Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Hydrochlorothiazide is combined with Amiodarone. |
Dantrolene | Dantrolene The risk or severity of hyperkalemia can be increased when Dantrolene is combined with Amiodarone. |
Chlorzoxazone | Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Amiodarone. |
Danazol | Danazol The metabolism of Amiodarone can be decreased when combined with Danazol. |
Disulfiram | Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Amiodarone. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The therapeutic efficacy of Propranolol can be increased when used in combination with Amiodarone. |
Minoxidil | Minoxidil The risk or severity of adverse effects can be increased when Amiodarone is combined with Minoxidil. |
Nortriptyline | Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Amiodarone. |
Spironolactone | Spironolactone The metabolism of Amiodarone can be decreased when combined with Spironolactone. |
Amphotericin B Injection | Amphotericin B Injection Amiodarone may decrease the nephrotoxic activities of Amphotericin B. |
Nadolol | Nadolol The therapeutic efficacy of Nadolol can be increased when used in combination with Amiodarone. |
Cholestyramine Resin | Cholestyramine Resin The serum concentration of Amiodarone can be decreased when it is combined with Cholestyramine. |
Oxytocin Injection | Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Amiodarone. |
Clomiphene | Clomiphene The serum concentration of Amiodarone can be increased when it is combined with Clomifene. |
Papaverine | Papaverine The risk or severity of QTc prolongation can be increased when Papaverine is combined with Amiodarone. |
Fluorouracil Injection | Fluorouracil Injection The metabolism of Amiodarone can be decreased when combined with Fluorouracil. |
Colchicine | Colchicine The metabolism of Colchicine can be decreased when combined with Amiodarone. |
Cephalexin | Cephalexin The metabolism of Amiodarone can be decreased when combined with Cephalexin. |
Dacarbazine | Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Amiodarone. |
Acetazolamide | Acetazolamide The metabolism of Amiodarone can be decreased when combined with Acetazolamide. |
Ketoconazole | Ketoconazole The metabolism of Amiodarone can be decreased when combined with Ketoconazole. |
Thiotepa Injection | Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Amiodarone. |
Vincristine Injection | Vincristine Injection The excretion of Vincristine can be decreased when combined with Amiodarone. |
Captopril | Captopril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amiodarone is combined with Captopril. |
Dipyridamole | Dipyridamole The risk or severity of adverse effects can be increased when Dipyridamole is combined with Amiodarone. |
Isoxsuprine | Isoxsuprine The risk or severity of adverse effects can be increased when Amiodarone is combined with Isoxsuprine. |
Vinblastine | Vinblastine The metabolism of Amiodarone can be decreased when combined with Vinblastine. |
Ethacrynic Acid | Ethacrynic Acid The risk or severity of adverse effects can be increased when Etacrynic acid is combined with Amiodarone. |
Metoprolol | Metoprolol The therapeutic efficacy of Metoprolol can be increased when used in combination with Amiodarone. |
Hydroxyzine | Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Amiodarone. |
Thiothixene | Thiothixene The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Thiothixene. |
Aspirin | Aspirin The metabolism of Amiodarone can be decreased when combined with Acetylsalicylic acid. |
Salsalate | Salsalate The risk or severity of hyperkalemia can be increased when Amiodarone is combined with Salsalate. |
Alprazolam | Alprazolam The metabolism of Alprazolam can be decreased when combined with Amiodarone. |
Triazolam | Triazolam The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Triazolam is combined with Amiodarone. |
Hyoscyamine | Hyoscyamine The risk or severity of adverse effects can be increased when Hyoscyamine is combined with Amiodarone. |
Trimethoprim | Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Amiodarone. |
Diltiazem | Diltiazem The risk or severity of adverse effects can be increased when Diltiazem is combined with Amiodarone. |
Nifedipine | Nifedipine The risk or severity of adverse effects can be increased when Amiodarone is combined with Nifedipine. |
Timolol | Timolol The therapeutic efficacy of Timolol can be increased when used in combination with Amiodarone. |
Verapamil | Verapamil The risk or severity of adverse effects can be increased when Verapamil is combined with Amiodarone. |
Atenolol | Atenolol The therapeutic efficacy of Atenolol can be increased when used in combination with Amiodarone. |
Pindolol | Pindolol The therapeutic efficacy of Pindolol can be increased when used in combination with Amiodarone. |
Cisplatin Injection | Cisplatin Injection The serum concentration of Cisplatin can be increased when it is combined with Amiodarone. |
Diflunisal | Diflunisal The risk or severity of hyperkalemia can be increased when Diflunisal is combined with Amiodarone. |
Piroxicam | Piroxicam The metabolism of Amiodarone can be decreased when combined with Piroxicam. |
Bumetanide | Bumetanide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Bumetanide is combined with Amiodarone. |
Etoposide | Etoposide The metabolism of Amiodarone can be increased when combined with Etoposide. |
Glyburide | Glyburide The metabolism of Amiodarone can be decreased when combined with Glyburide. |
Glipizide | Glipizide The metabolism of Glipizide can be decreased when combined with Amiodarone. |
Indapamide | Indapamide The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Indapamide. |
Dicloxacillin | Dicloxacillin The metabolism of Amiodarone can be increased when combined with Dicloxacillin. |
Nafcillin Injection | Nafcillin Injection The therapeutic efficacy of Amiodarone can be decreased when used in combination with Nafcillin. |
Pentoxifylline | Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Amiodarone. |
Pentamidine Injection | Pentamidine Injection The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Pentamidine. |
Labetalol | Labetalol The therapeutic efficacy of Labetalol can be increased when used in combination with Amiodarone. |
Leuprolide Injection | Leuprolide Injection The risk or severity of QTc prolongation can be increased when Leuprolide is combined with Amiodarone. |
Gemfibrozil | Gemfibrozil The metabolism of Amiodarone can be decreased when combined with Gemfibrozil. |
Guanabenz | Guanabenz The metabolism of Guanabenz can be decreased when combined with Amiodarone. |
Ketoprofen | Ketoprofen The metabolism of Amiodarone can be decreased when combined with Ketoprofen. |
Pimozide | Pimozide The metabolism of Amiodarone can be decreased when combined with Pimozide. |
Enalapril | Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amiodarone is combined with Enalapril. |
Flurbiprofen | Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Amiodarone. |
Buspirone | Buspirone The metabolism of Buspirone can be decreased when combined with Amiodarone. |
Lovastatin | Lovastatin The serum concentration of Lovastatin can be increased when it is combined with Amiodarone. |
Ciprofloxacin | Ciprofloxacin The metabolism of Ciprofloxacin can be decreased when combined with Amiodarone. |
Mesalamine | Mesalamine The risk or severity of hyperkalemia can be increased when Mesalazine is combined with Amiodarone. |
Diclofenac | Diclofenac The metabolism of Amiodarone can be decreased when combined with Diclofenac. |
Fluoxetine | Fluoxetine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Fluoxetine. |
Nimodipine | Nimodipine The risk or severity of adverse effects can be increased when Amiodarone is combined with Nimodipine. |
Clozapine | Clozapine The metabolism of Clozapine can be increased when combined with Amiodarone. |
Idarubicin | Idarubicin The metabolism of Idarubicin can be decreased when combined with Amiodarone. |
Ofloxacin | Ofloxacin The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Amiodarone. |
Clarithromycin | Clarithromycin The metabolism of Amiodarone can be decreased when combined with Clarithromycin. |
Benazepril | Benazepril The risk or severity of hyperkalemia can be increased when Benazepril is combined with Amiodarone. |
Etodolac | Etodolac The metabolism of Etodolac can be decreased when combined with Amiodarone. |
Felodipine | Felodipine The risk or severity of adverse effects can be increased when Felodipine is combined with Amiodarone. |
Fosinopril | Fosinopril The risk or severity of hyperkalemia can be increased when Fosinopril is combined with Amiodarone. |
Nabumetone | Nabumetone The metabolism of Nabumetone can be decreased when combined with Amiodarone. |
Pravastatin | Pravastatin The metabolism of Pravastatin can be increased when combined with Amiodarone. |
Quinapril | Quinapril The risk or severity of hyperkalemia can be increased when Quinapril is combined with Amiodarone. |
Ramipril | Ramipril The risk or severity of hyperkalemia can be increased when Ramipril is combined with Amiodarone. |
Simvastatin | Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Amiodarone. |
Amlodipine | Amlodipine The risk or severity of adverse effects can be increased when Amlodipine is combined with Amiodarone. |
Teniposide Injection | Teniposide Injection The metabolism of Amiodarone can be decreased when combined with Teniposide. |
Itraconazole | Itraconazole The metabolism of Amiodarone can be decreased when combined with Itraconazole. |
Lisinopril | Lisinopril The risk or severity of hyperkalemia can be increased when Lisinopril is combined with Amiodarone. |
Oxaprozin | Oxaprozin The risk or severity of hyperkalemia can be increased when Oxaprozin is combined with Amiodarone. |
Rifabutin | Rifabutin The metabolism of Amiodarone can be increased when combined with Rifabutin. |
Sotalol | Sotalol The therapeutic efficacy of Sotalol can be increased when used in combination with Amiodarone. |
Bisoprolol | Bisoprolol The therapeutic efficacy of Amiodarone can be increased when used in combination with Bisoprolol. |
Zolpidem | Zolpidem The metabolism of Zolpidem can be decreased when combined with Amiodarone. |
Doxazosin | Doxazosin The metabolism of Doxazosin can be decreased when combined with Amiodarone. |
Terazosin | Terazosin The risk or severity of hypotension can be increased when Terazosin is combined with Amiodarone. |
Isradipine | Isradipine The risk or severity of adverse effects can be increased when Isradipine is combined with Amiodarone. |
Omeprazole | Omeprazole The metabolism of Amiodarone can be increased when combined with Omeprazole. |
Cisapride | Cisapride The metabolism of Amiodarone can be decreased when combined with Cisapride. |
Fluvastatin | Fluvastatin The metabolism of Fluvastatin can be increased when combined with Amiodarone. |
Venlafaxine | Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Amiodarone. |
Nizatidine | Nizatidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nizatidine is combined with Amiodarone. |
Stavudine | Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Stavudine is combined with Amiodarone. |
Famciclovir | Famciclovir The metabolism of Amiodarone can be decreased when combined with Famciclovir. |
Fluvoxamine | Fluvoxamine The metabolism of Amiodarone can be decreased when combined with Fluvoxamine. |
Nefazodone | Nefazodone The metabolism of Amiodarone can be decreased when combined with Nefazodone. |
Lamotrigine | Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Amiodarone. |
Losartan | Losartan The risk or severity of adverse effects can be increased when Losartan is combined with Amiodarone. |
Tramadol | Tramadol The metabolism of Amiodarone can be decreased when combined with Tramadol. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Vinorelbine can be decreased when combined with Amiodarone. |
Moexipril | Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Amiodarone. |
Lansoprazole | Lansoprazole The metabolism of Amiodarone can be increased when combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Amiodarone can be increased when combined with Ifosfamide. |
Nicardipine | Nicardipine The risk or severity of adverse effects can be increased when Nicardipine is combined with Amiodarone. |
Bupropion | Bupropion The metabolism of Bupropion can be decreased when combined with Amiodarone. |
Ticlopidine | Ticlopidine The metabolism of Amiodarone can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Amiodarone. |
Metformin | Metformin The serum concentration of Metformin can be increased when it is combined with Amiodarone. |
Dalteparin Injection | Dalteparin Injection The risk or severity of hyperkalemia can be increased when Amiodarone is combined with Dalteparin. |
Nisoldipine | Nisoldipine The risk or severity of adverse effects can be increased when Nisoldipine is combined with Amiodarone. |
Lamivudine | Lamivudine The serum concentration of Lamivudine can be increased when it is combined with Amiodarone. |
Riluzole | Riluzole The metabolism of Riluzole can be decreased when combined with Amiodarone. |
Amifostine Injection | Amifostine Injection The risk or severity of adverse effects can be increased when Amiodarone is combined with Amifostine. |
Acarbose | Acarbose The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Acarbose. |
Glimepiride | Glimepiride The risk or severity of adverse effects can be increased when Glimepiride is combined with Amiodarone. |
Anastrozole | Anastrozole The metabolism of Amiodarone can be decreased when combined with Anastrozole. |
Gemcitabine Injection | Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Amiodarone. |
Indinavir | Indinavir The serum concentration of Amiodarone can be increased when it is combined with Indinavir. |
Ritonavir | Ritonavir The metabolism of Amiodarone can be decreased when combined with Ritonavir. |
Docetaxel Injection | Docetaxel Injection The metabolism of Amiodarone can be decreased when combined with Docetaxel. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be decreased when combined with Amiodarone. |
Zafirlukast | Zafirlukast The metabolism of Amiodarone can be decreased when combined with Zafirlukast. |
Mirtazapine | Mirtazapine The metabolism of Amiodarone can be decreased when combined with Mirtazapine. |
Trandolapril | Trandolapril The risk or severity of hyperkalemia can be increased when Trandolapril is combined with Amiodarone. |
Topiramate | Topiramate The metabolism of Amiodarone can be increased when combined with Topiramate. |
Zileuton | Zileuton The metabolism of Zileuton can be decreased when combined with Amiodarone. |
Valsartan | Valsartan The metabolism of Valsartan can be decreased when combined with Amiodarone. |
Insulin Lispro Injection | Insulin Lispro Injection The risk or severity of hypoglycemia can be increased when Amiodarone is combined with Insulin lispro. |
Pramipexole | Pramipexole The serum concentration of Amiodarone can be increased when it is combined with Pramipexole. |
Donepezil | Donepezil The metabolism of Donepezil can be decreased when combined with Amiodarone. |
Nelfinavir | Nelfinavir The serum concentration of Nelfinavir can be increased when it is combined with Amiodarone. |
Fexofenadine | Fexofenadine The serum concentration of Amiodarone can be increased when it is combined with Fexofenadine. |
Azithromycin | Azithromycin The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Amiodarone. |
Loratadine | Loratadine The risk or severity of QTc prolongation can be increased when Loratadine is combined with Amiodarone. |
Carvedilol | Carvedilol The therapeutic efficacy of Carvedilol can be increased when used in combination with Amiodarone. |
Nilutamide | Nilutamide The metabolism of Amiodarone can be decreased when combined with Nilutamide. |
Flutamide | Flutamide The metabolism of Flutamide can be decreased when combined with Amiodarone. |
Selegiline | Selegiline The metabolism of Amiodarone can be decreased when combined with Selegiline. |
Bicalutamide | Bicalutamide The metabolism of Amiodarone can be decreased when combined with Bicalutamide. |
Sertraline | Sertraline The metabolism of Sertraline can be decreased when combined with Amiodarone. |
Propafenone | Propafenone The risk or severity of adverse effects can be increased when Amiodarone is combined with Propafenone. |
Letrozole | Letrozole The metabolism of Letrozole can be decreased when combined with Amiodarone. |
Raloxifene | Raloxifene The metabolism of Amiodarone can be decreased when combined with Raloxifene. |
Irbesartan | Irbesartan The metabolism of Amiodarone can be decreased when combined with Irbesartan. |
Tamsulosin | Tamsulosin The risk or severity of hypotension can be increased when Amiodarone is combined with Tamsulosin. |
Ropinirole | Ropinirole The risk or severity of adverse effects can be increased when Amiodarone is combined with Ropinirole. |
Quetiapine | Quetiapine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Quetiapine. |
Cetirizine | Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Amiodarone. |
Paroxetine | Paroxetine The metabolism of Amiodarone can be decreased when combined with Paroxetine. |
Tolcapone | Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Amiodarone. |
Citalopram | Citalopram The metabolism of Amiodarone can be decreased when combined with Citalopram. |
Capecitabine | Capecitabine The metabolism of Capecitabine can be decreased when combined with Amiodarone. |
Efavirenz | Efavirenz The serum concentration of Amiodarone can be decreased when it is combined with Efavirenz. |
Sildenafil | Sildenafil The metabolism of Sildenafil can be decreased when combined with Amiodarone. |
Pioglitazone | Pioglitazone The metabolism of Amiodarone can be decreased when combined with Pioglitazone. |
Celecoxib | Celecoxib The metabolism of Celecoxib can be decreased when combined with Amiodarone. |
Rosiglitazone | Rosiglitazone The metabolism of Amiodarone can be decreased when combined with Rosiglitazone. |
Tolterodine | Tolterodine The metabolism of Tolterodine can be decreased when combined with Amiodarone. |
Thalidomide | Thalidomide The metabolism of Amiodarone can be decreased when combined with Thalidomide. |
Colesevelam | Colesevelam The excretion of Amiodarone can be increased when combined with Colesevelam. |
Balsalazide | Balsalazide The risk or severity of hyperkalemia can be increased when Balsalazide is combined with Amiodarone. |
Nateglinide | Nateglinide The metabolism of Nateglinide can be decreased when combined with Amiodarone. |
Galantamine | Galantamine The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Galantamine. |
Rabeprazole | Rabeprazole The metabolism of Amiodarone can be decreased when combined with Rabeprazole. |
Terbinafine | Terbinafine The metabolism of Terbinafine can be increased when combined with Amiodarone. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists