Solifenacin

Generic name: Pronounced as (sol i fen' a cin)
Brand names
  • VESIcare LS®
  • VESIcare®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 07/15/2020

Solifenacin (VESIcare) is used to treat overactive bladder (a condition in which the bladder muscles contract uncontrollably and cause frequent urination, urgent need to urinate, and inability to control urination). Solifenacin (VESIcare LS) is used to treat neurogenic detrusor overactivity (a bladder control condition caused by brain, spinal cord or nerve problem) in children 2 years of age and older. Solifenacin is in a class of medications called antimuscarinics. It works by relaxing the bladder muscles.

Solifenacin comes as a tablet (VESIcare) and a suspension (liquid; VESIcare LS) to take by mouth. Solifenacin tablets are usually taken once a day with or without food. Solifenacin suspension (VESIcare LS) is usually taken once a day. To help you remember to take solifenacin, take it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take solifenacin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well before each use to mix the medication evenly. Use an oral dosing syringe to measure the correct amount of medication. You can swallow the suspension straight from the syringe followed by a small glass of water or milk. To avoid a bitter taste, avoid taking the suspension with another liquid or food.

Swallow the tablets whole; do not split, chew, or crush them. Swallow the tablets with water or another liquid.

Your doctor will probably start you on a low dose of solifenacin and increase your dose later in your treatment.

Solifenacin may help to control your symptoms but will not cure your condition. Continue to take solifenacin even if you feel well. Do not stop taking solifenacin without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking solifenacin,

  • tell your doctor and pharmacist if you are allergic to solifenacin, any other medications, or any of the ingredients in solifenacin tablets or oral suspension. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and and herbal products you are taking. Be sure to mention any of the following: amiodarone (Nexterone, Pacerone); clarithromycin; disopyramide (Norpace); dofetilide (Tikosyn); erythromycin (E.E.S., ERYC, Erythrocin); HIV protease inhibitors such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra, in Viekira), and saquinavir (Invirase); itraconazole (Sporanox), ketoconazole, nefazodone; pimozide; procainamide; quinidine (in Neudexta); sotalol (Betapace, Sorine, Sotylize); and thioridazine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with solifenacin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have or have ever had narrow angle glaucoma (a serious eye condition that may cause vision loss), urinary retention (inability to empty your bladder completely or at all), or gastric retention (slow emptying of your stomach). Your doctor may tell you not to take solifenacin.

  • tell your doctor if you have or have ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), any type of blockage in the bladder or digestive system, myasthenia gravis (a disorder of the nervous system that causes muscle weakness), ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum), benign prostatic hypertrophy (BPH, enlargement of the prostate, a male reproductive organ), constipation; or liver or kidney disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking solifenacin, call your doctor.

  • you should know that solifenacin may make you dizzy or drowsy or cause blurred vision. Do not drive a car or operate machinery until you know how this medication affects you.

  • you should know that solifenacin may make it harder for your body to cool down when it gets very hot. Avoid exposure to extreme heat, and call your doctor or get emergency medical treatment if you have fever or other signs of heat stroke such as dizziness, upset stomach, headache, confusion, and fast pulse after you are exposed to heat.

Talk to your doctor about drinking grapefruit juice while taking this medicine.

If you are taking solifenacin tablets (VESIcare), skip the missed dose and take your next dose at the regular time the next day. Do not take two doses of solifenacin tablets in the same day.

If you are taking solifenacin oral suspension (VESIcare LS), take the missed dose as soon as you remember it. However, if it has been more than 12 hours since your last dose, skip the missed dose and continue your regular dosing schedule. Do not take two doses of solifenacin oral suspension in the same day.

  • Solifenacin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • dry mouth

    • constipation

    • stomach pain

    • upset stomach

    • vomiting

    • heartburn

    • dry eyes

    • blurred vision

    • dry skin

  • Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

    • constipation that lasts longer than 3 days

    • painful or frequent urination

    • bloody or cloudy urine

    • back pain

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • hoarseness

    • difficulty breathing or swallowing

    • rash

    • hives

    • itching

    • hallucinations (seeing things or hearing voices that do not exist)

    • confusion

    • headache

    • extreme tiredness

  • Solifenacin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • flushing

  • dry mouth

  • dry eyes

  • dry skin

  • blurred vision

  • enlarged pupils (black circle in the middle of the eye)

  • confusion

  • fever

  • fast heartbeat

  • shaking hands that you cannot control

  • difficulty walking

  • hallucinations (seeing things or hearing voices that do not exist)

Keep all appointments with your doctor .

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Moxifloxacin.
Delavirdine Delavirdine The metabolism of Solifenacin can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Solifenacin can be decreased when combined with Nevirapine.
Dolasetron Dolasetron The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Dolasetron.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Anagrelide.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Solifenacin.
Candesartan Candesartan Solifenacin may decrease the antihypertensive activities of Candesartan.
Cilostazol Cilostazol The risk or severity of QTc prolongation can be increased when Cilostazol is combined with Solifenacin.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Solifenacin.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Erythromycin.
Guanfacine Guanfacine Guanfacine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Magnesium Hydroxide Magnesium Hydroxide The therapeutic efficacy of Magnesium hydroxide can be decreased when used in combination with Solifenacin.
Magnesium Oxide Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Solifenacin.
Methylergonovine Methylergonovine The risk or severity of hypertension can be increased when Methylergometrine is combined with Solifenacin.
Naratriptan Naratriptan Naratriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Olsalazine Olsalazine The risk or severity of hypertension can be increased when Olsalazine is combined with Solifenacin.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Solifenacin.
Penbutolol Penbutolol The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Solifenacin.
Polyethylene glycol-electrolyte solution (PEG-ES) Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Solifenacin.
Psyllium Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Solifenacin.
Ranitidine Ranitidine The metabolism of Solifenacin can be decreased when combined with Ranitidine.
Reserpine Reserpine Reserpine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Rizatriptan Rizatriptan Rizatriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Sumatriptan Sumatriptan Sumatriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Tacrolimus Tacrolimus The risk or severity of QTc prolongation can be increased when Tacrolimus is combined with Solifenacin.
Tizanidine Tizanidine Tizanidine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Zolmitriptan Zolmitriptan Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Famotidine Injection Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Solifenacin.
Fluconazole Injection Fluconazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Solifenacin.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Solifenacin.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Solifenacin.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Levofloxacin.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Solifenacin is combined with Meperidine.
Metoclopramide Injection Metoclopramide Injection The therapeutic efficacy of Solifenacin can be decreased when used in combination with Metoclopramide.
Metronidazole Injection Metronidazole Injection The risk or severity of QTc prolongation can be increased when Metronidazole is combined with Solifenacin.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Solifenacin.
Altretamine Altretamine Amphetamine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Solifenacin.
Ondansetron Ondansetron The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ondansetron.
Granisetron Granisetron The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Granisetron.
Torsemide Torsemide Solifenacin may decrease the antihypertensive activities of Torasemide.
Olanzapine Olanzapine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Alosetron Alosetron Alosetron may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dofetilide Dofetilide The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Dofetilide.
Entacapone Entacapone Entacapone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Eprosartan Eprosartan Solifenacin may decrease the antihypertensive activities of Eprosartan.
Hydroxychloroquine Hydroxychloroquine The metabolism of Solifenacin can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The risk or severity of hypertension can be increased when Meloxicam is combined with Solifenacin.
Oxcarbazepine Oxcarbazepine Oxcarbazepine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Telmisartan Telmisartan Solifenacin may decrease the antihypertensive activities of Telmisartan.
Zaleplon Zaleplon Zaleplon may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Anakinra Anakinra The metabolism of Solifenacin can be increased when combined with Anakinra.
Desloratadine Desloratadine Solifenacin may increase the central nervous system depressant (CNS depressant) activities of Desloratadine.
Linezolid Linezolid Linezolid may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Rivastigmine Rivastigmine The therapeutic efficacy of Solifenacin can be decreased when used in combination with Rivastigmine.
Trimipramine Trimipramine The metabolism of Solifenacin can be decreased when combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Solifenacin can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate The risk or severity of adverse effects can be increased when Solifenacin is combined with Glycopyrronium.
Perindopril Perindopril Solifenacin may decrease the antihypertensive activities of Perindopril.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Solifenacin.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Dutasteride is combined with Solifenacin.
Epinephrine Injection Epinephrine Injection The risk or severity of hypertension can be increased when Epinephrine is combined with Solifenacin.
Eplerenone Eplerenone Solifenacin may decrease the antihypertensive activities of Eplerenone.
Escitalopram Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Solifenacin.
Olmesartan Olmesartan Solifenacin may decrease the antihypertensive activities of Olmesartan.
Zonisamide Zonisamide Zonisamide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Adalimumab Injection Adalimumab Injection The metabolism of Solifenacin can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole Aripiprazole may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Atomoxetine Atomoxetine Atomoxetine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dexmethylphenidate Dexmethylphenidate Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Atazanavir Atazanavir The risk or severity of QTc prolongation can be increased when Atazanavir is combined with Solifenacin.
Almotriptan Almotriptan Almotriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Eletriptan Eletriptan Eletriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Mefloquine Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Solifenacin.
Polyethylene Glycol 3350 Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Solifenacin.
Vardenafil Vardenafil The risk or severity of QTc prolongation can be increased when Vardenafil is combined with Solifenacin.
Alfuzosin Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Solifenacin.
Memantine Memantine The therapeutic efficacy of Solifenacin can be decreased when used in combination with Memantine.
Tegaserod Tegaserod The metabolism of Tegaserod can be decreased when combined with Solifenacin.
Tadalafil Tadalafil Solifenacin may decrease the antihypertensive activities of Tadalafil.
Frovatriptan Frovatriptan Frovatriptan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Solifenacin can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection Apomorphine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Infliximab Injection Infliximab Injection The metabolism of Solifenacin can be increased when combined with Infliximab.
Protriptyline Protriptyline Protriptyline may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Duloxetine Duloxetine The metabolism of Solifenacin can be decreased when combined with Duloxetine.
Trospium Trospium The risk or severity of adverse effects can be increased when Trospium is combined with Solifenacin.
Bosentan Bosentan Solifenacin may decrease the antihypertensive activities of Bosentan.
Cinacalcet Cinacalcet The metabolism of Solifenacin can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Solifenacin.
Eszopiclone Eszopiclone Eszopiclone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Voriconazole Voriconazole The risk or severity of QTc prolongation can be increased when Voriconazole is combined with Solifenacin.
Dextroamphetamine Dextroamphetamine Amphetamine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Solifenacin can be decreased when combined with Peginterferon alfa-2b.
Pramlintide Injection Pramlintide Injection The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Solifenacin.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Solifenacin.
Isocarboxazid Isocarboxazid Isocarboxazid may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ramelteon Ramelteon Ramelteon may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Solifenacin.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Solifenacin is combined with Fentanyl.
Pregabalin Pregabalin Pregabalin may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Phenylephrine Phenylephrine The risk or severity of hypertension can be increased when Phenylephrine is combined with Solifenacin.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Solifenacin.
Felbamate Felbamate Felbamate may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ranolazine Ranolazine The serum concentration of Solifenacin can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Solifenacin can be increased when combined with Abatacept.
Rasagiline Rasagiline Rasagiline may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Imatinib Imatinib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Imatinib.
Gefitinib Gefitinib The metabolism of Solifenacin can be decreased when combined with Gefitinib.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Solifenacin.
Paliperidone Paliperidone The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Paliperidone.
Bortezomib Bortezomib The risk or severity of QTc prolongation can be increased when Bortezomib is combined with Solifenacin.
Lubiprostone Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Solifenacin.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Oxaliplatin.
Posaconazole Posaconazole The risk or severity of QTc prolongation can be increased when Posaconazole is combined with Solifenacin.
Primaquine Primaquine The metabolism of Primaquine can be decreased when combined with Solifenacin.
Aliskiren Aliskiren Solifenacin may decrease the antihypertensive activities of Aliskiren.
Dimenhydrinate Dimenhydrinate The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine The metabolism of Solifenacin can be decreased when combined with Lisdexamfetamine.
Nabilone Nabilone The risk or severity of Tachycardia and drowsiness can be increased when Solifenacin is combined with Nabilone.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Vorinostat.
Sorafenib Sorafenib The metabolism of Solifenacin can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Solifenacin.
Dronabinol Dronabinol The risk or severity of Tachycardia and drowsiness can be increased when Solifenacin is combined with Dronabinol.
Lapatinib Lapatinib The risk or severity of QTc prolongation can be increased when Lapatinib is combined with Solifenacin.
Levocetirizine Levocetirizine Levocetirizine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dasatinib Dasatinib The risk or severity of QTc prolongation can be increased when Dasatinib is combined with Solifenacin.
Mexiletine Mexiletine The metabolism of Solifenacin can be decreased when combined with Mexiletine.
Paclitaxel (with polyoxyethylated castor oil) Injection Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Solifenacin.
Temsirolimus Temsirolimus The metabolism of Solifenacin can be decreased when combined with Temsirolimus.
Nilotinib Nilotinib The metabolism of Nilotinib can be decreased when combined with Solifenacin.
Toremifene Toremifene The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Toremifene.
Desmopressin Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Solifenacin.
Betaine Betaine The therapeutic efficacy of Solifenacin can be decreased when used in combination with Glycine betaine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Solifenacin is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Solifenacin is combined with Botulinum Toxin Type B.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine Desvenlafaxine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Cevimeline Cevimeline The metabolism of Solifenacin can be decreased when combined with Cevimeline.
Nebivolol Nebivolol Solifenacin may decrease the antihypertensive activities of Nebivolol.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Solifenacin.
Certolizumab Injection Certolizumab Injection The metabolism of Solifenacin can be increased when combined with Certolizumab pegol.
Rufinamide Rufinamide Rufinamide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Midazolam Midazolam Midazolam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Naltrexone Injection Naltrexone Injection The risk or severity of adverse effects can be increased when Solifenacin is combined with Naltrexone.
Milnacipran Milnacipran Milnacipran may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Sodium Phosphate Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Solifenacin.
Fesoterodine Fesoterodine The risk or severity of adverse effects can be increased when Solifenacin is combined with Fesoterodine.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Degarelix.
Betaxolol Betaxolol The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Betaxolol.
Iloperidone Iloperidone The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Iloperidone.
Lacosamide Lacosamide Lacosamide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Everolimus Everolimus The metabolism of Solifenacin can be decreased when combined with Everolimus.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Solifenacin.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Solifenacin is combined with Botulinum toxin type A.
Palonosetron Injection Palonosetron Injection Palonosetron may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Romidepsin.
Tapentadol Tapentadol The risk or severity of adverse effects can be increased when Tapentadol is combined with Solifenacin.
Golimumab Injection Golimumab Injection The metabolism of Solifenacin can be increased when combined with Golimumab.
Pazopanib Pazopanib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Pazopanib.
Asenapine Asenapine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Asenapine.
Vigabatrin Vigabatrin Vigabatrin may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Oxymorphone is combined with Solifenacin.
Tocilizumab Injection Tocilizumab Injection The metabolism of Solifenacin can be increased when combined with Tocilizumab.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Eribulin.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Solifenacin is combined with Botulinum toxin type A.
Lurasidone Lurasidone Lurasidone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Acetaminophen Injection Acetaminophen Injection The metabolism of Solifenacin can be decreased when combined with Acetaminophen.
Vilazodone Vilazodone The metabolism of Solifenacin can be decreased when combined with Vilazodone.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Solifenacin.
Rilpivirine Rilpivirine The metabolism of Solifenacin can be decreased when combined with Rilpivirine.
Abiraterone Abiraterone The metabolism of Solifenacin can be decreased when combined with Abiraterone.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Triptorelin.
Vandetanib Vandetanib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Vandetanib.
Clobazam Clobazam The metabolism of Solifenacin can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Vemurafenib.
Crizotinib Crizotinib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Crizotinib.
Cabergoline Cabergoline Cabergoline may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ambrisentan Ambrisentan Solifenacin may decrease the antihypertensive activities of Ambrisentan.
Ezogabine Ezogabine Tiagabine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Mirabegron Mirabegron The risk or severity of adverse effects can be increased when Mirabegron is combined with Solifenacin.
Linaclotide Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Solifenacin.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Bedaquiline.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Solifenacin.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Solifenacin.
Pomalidomide Pomalidomide Pomalidomide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dabrafenib Dabrafenib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Solifenacin can be decreased when combined with Ospemifene.
Levomilnacipran Levomilnacipran Levomilnacipran may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Vortioxetine Vortioxetine Vortioxetine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Solifenacin.
Ketorolac Injection Ketorolac Injection The risk or severity of hypertension can be increased when Ketorolac is combined with Solifenacin.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Solifenacin.
Apremilast Apremilast The metabolism of Solifenacin can be increased when combined with Apremilast.
Droxidopa Droxidopa The risk or severity of hypertension can be increased when Solifenacin is combined with Droxidopa.
Ceritinib Ceritinib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Solifenacin can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Oritavancin Injection Oritavancin Injection The metabolism of Solifenacin can be decreased when combined with Oritavancin.
Hydrocodone Hydrocodone The risk or severity of adverse effects can be increased when Hydrocodone is combined with Solifenacin.
Suvorexant Suvorexant Suvorexant may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Methamphetamine Methamphetamine Metamfetamine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Tasimelteon Tasimelteon Tasimelteon may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Riociguat Riociguat Solifenacin may decrease the antihypertensive activities of Riociguat.
Secukinumab Injection Secukinumab Injection The metabolism of Solifenacin can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection Risperidone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Lenvatinib Lenvatinib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Solifenacin can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Panobinostat can be decreased when combined with Solifenacin.
Haloperidol Injection Haloperidol Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Haloperidol.
Ivabradine Ivabradine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ivabradine.
Macitentan Macitentan Solifenacin may decrease the antihypertensive activities of Macitentan.
Flibanserin Flibanserin Flibanserin may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Rolapitant Rolapitant The metabolism of Solifenacin can be decreased when combined with Rolapitant.
Brexpiprazole Brexpiprazole Brexpiprazole may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ziprasidone.
Cariprazine Cariprazine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Eluxadoline Eluxadoline The risk or severity of constipation can be increased when Solifenacin is combined with Eluxadoline.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Solifenacin.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Cobicistat Cobicistat The metabolism of Solifenacin can be decreased when combined with Cobicistat.
Midodrine Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Solifenacin.
Selexipag Selexipag Solifenacin may decrease the antihypertensive activities of Selexipag.
Pimavanserin Pimavanserin Pimavanserin may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Diphenhydramine Injection Diphenhydramine Injection Diphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Furosemide Injection Furosemide Injection Solifenacin may decrease the antihypertensive activities of Furosemide.
Rucaparib Rucaparib The metabolism of Solifenacin can be decreased when combined with Rucaparib.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ribociclib.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Plecanatide Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Solifenacin.
Deutetrabenazine Deutetrabenazine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Deutetrabenazine.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Solifenacin.
Safinamide Safinamide Safinamide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Midostaurin Midostaurin The metabolism of Solifenacin can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Solifenacin can be decreased when combined with Enasidenib.
Delafloxacin Delafloxacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Delafloxacin.
Letermovir Letermovir The metabolism of Letermovir can be decreased when combined with Solifenacin.
Tetrabenazine Tetrabenazine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Tetrabenazine.
Buprenorphine Injection Buprenorphine Injection The risk or severity of adverse effects can be increased when Buprenorphine is combined with Solifenacin.
Lofexidine Lofexidine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Lofexidine.
Eliglustat Eliglustat The metabolism of Solifenacin can be decreased when combined with Eliglustat.
Encorafenib Encorafenib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Encorafenib.
Ivosidenib Ivosidenib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ivosidenib.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Solifenacin.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Solifenacin.
Cannabidiol Cannabidiol The risk or severity of Tachycardia and drowsiness can be increased when Solifenacin is combined with Cannabidiol.
Dacomitinib Dacomitinib The metabolism of Solifenacin can be decreased when combined with Dacomitinib.
Stiripentol Stiripentol The metabolism of Solifenacin can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Gilteritinib.
Glasdegib Glasdegib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Glasdegib.
Rifamycin Rifamycin The metabolism of Solifenacin can be decreased when combined with Rifamycin.
Prucalopride Prucalopride The therapeutic efficacy of Prucalopride can be decreased when used in combination with Solifenacin.
Magnesium Citrate Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Solifenacin.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Solifenacin can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of hypertension can be increased when Solifenacin is combined with Siponimod.
Brexanolone Injection Brexanolone Injection Brexanolone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Solifenacin.
Triclabendazole Triclabendazole The metabolism of Solifenacin can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Entrectinib.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Solifenacin.
Pitolisant Pitolisant The serum concentration of Solifenacin can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Solifenacin can be decreased when combined with Fedratinib.
Lefamulin Lefamulin Lefamulin may increase the QTc-prolonging activities of Solifenacin.
Phenytoin Injection Phenytoin Injection Phenytoin may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Fosphenytoin Injection Fosphenytoin Injection Fosphenytoin may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Lumateperone Lumateperone Lumateperone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Lasmiditan Lasmiditan Lasmiditan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Cenobamate Cenobamate The serum concentration of Solifenacin can be decreased when it is combined with Cenobamate.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Solifenacin.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Solifenacin is combined with Selpercatinib.
Lemborexant Lemborexant Lemborexant may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Fenfluramine Fenfluramine Fenfluramine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Fostemsavir Fostemsavir The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Fostemsavir.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Solifenacin.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Solifenacin can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Solifenacin is combined with Naxitamab.
Relugolix Relugolix The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Relugolix.
Vibegron Vibegron Solifenacin may increase the smooth muscle relaxing activities of Vibegron.
Viloxazine Viloxazine Viloxazine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Theophylline Theophylline The metabolism of Solifenacin can be decreased when combined with Theophylline.
Fenoprofen Fenoprofen The risk or severity of hypertension can be increased when Fenoprofen is combined with Solifenacin.
Indomethacin Indomethacin The risk or severity of hypertension can be increased when Indomethacin is combined with Solifenacin.
Mefenamic Acid Mefenamic Acid The risk or severity of hypertension can be increased when Mefenamic acid is combined with Solifenacin.
Naproxen Naproxen The risk or severity of hypertension can be increased when Naproxen is combined with Solifenacin.
Tolmetin Tolmetin The risk or severity of hypertension can be increased when Tolmetin is combined with Solifenacin.
Sulindac Sulindac The risk or severity of hypertension can be increased when Sulindac is combined with Solifenacin.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Solifenacin.
Hydroxyurea Hydroxyurea The metabolism of Solifenacin can be decreased when combined with Hydroxyurea.
Phenobarbital Phenobarbital Phenobarbital may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Metaxalone Metaxalone Metaxalone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Solifenacin.
Primidone Primidone Primidone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Methsuximide Methsuximide Methsuximide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Diethylpropion Diethylpropion Diethylpropion may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Chlorpromazine Chlorpromazine The metabolism of Solifenacin can be decreased when combined with Chlorpromazine.
Diazepam Diazepam Diazepam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Oxazepam Oxazepam Oxazepam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Flurazepam Flurazepam Flurazepam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Clorazepate Clorazepate Clorazepic acid may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Lorazepam Lorazepam Lorazepam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Phenoxybenzamine Phenoxybenzamine The risk or severity of hypertension can be increased when Phenoxybenzamine is combined with Solifenacin.
Amantadine Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Solifenacin.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Solifenacin.
Meprobamate Meprobamate Meprobamate may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Chlordiazepoxide Chlordiazepoxide Chlordiazepoxide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Bromocriptine Bromocriptine Bromocriptine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Metaproterenol Metaproterenol The risk or severity of hypertension can be increased when Orciprenaline is combined with Solifenacin.
Tranylcypromine Tranylcypromine The metabolism of Solifenacin can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Solifenacin can be decreased when combined with Phenelzine.
Procarbazine Procarbazine Procarbazine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ergoloid Mesylates Ergoloid Mesylates Ergoloid mesylate may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Prochlorperazine Prochlorperazine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Prochlorperazine.
Thioridazine Thioridazine The metabolism of Thioridazine can be decreased when combined with Solifenacin.
Trifluoperazine Trifluoperazine Trifluoperazine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Solifenacin.
Methadone Methadone The risk or severity of adverse effects can be increased when Solifenacin is combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Solifenacin can be decreased when combined with Oxybutynin.
Benztropine Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Solifenacin.
Maprotiline Maprotiline Maprotiline may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ibuprofen Ibuprofen The risk or severity of hypertension can be increased when Ibuprofen is combined with Solifenacin.
Trihexyphenidyl Trihexyphenidyl The risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Solifenacin.
Orphenadrine Orphenadrine The metabolism of Solifenacin can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Fluphenazine Fluphenazine Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Phentermine Phentermine The risk or severity of hypertension can be increased when Phentermine is combined with Solifenacin.
Methylphenidate Methylphenidate The risk or severity of hypertension can be increased when Methylphenidate is combined with Solifenacin.
Amoxapine Amoxapine The metabolism of Solifenacin can be decreased when combined with Amoxapine.
Sulfasalazine Sulfasalazine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Solifenacin.
Doxorubicin Doxorubicin The metabolism of Solifenacin can be decreased when combined with Doxorubicin.
Mechlorethamine Mechlorethamine The therapeutic efficacy of Solifenacin can be decreased when used in combination with Mechlorethamine.
Pyridostigmine Pyridostigmine The therapeutic efficacy of Solifenacin can be decreased when used in combination with Pyridostigmine.
Carbamazepine Carbamazepine Carbamazepine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Molindone Molindone Molindone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Methyldopa Methyldopa Solifenacin may decrease the antihypertensive activities of Methyldopa.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Solifenacin.
Prazosin Prazosin Solifenacin may decrease the antihypertensive activities of Prazosin.
Hydralazine Hydralazine Solifenacin may decrease the antihypertensive activities of Hydralazine.
Cimetidine Cimetidine The metabolism of Solifenacin can be decreased when combined with Cimetidine.
Clonazepam Clonazepam Clonazepam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Loperamide Loperamide The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Loperamide.
Promethazine Promethazine Promethazine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Meclofenamate Meclofenamate The risk or severity of hypertension can be increased when Meclofenamic acid is combined with Solifenacin.
Digoxin Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Solifenacin.
Loxapine Loxapine Loxapine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Solifenacin.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Solifenacin.
Ethosuximide Ethosuximide Ethosuximide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Solifenacin.
Chlorothiazide Chlorothiazide The serum concentration of Chlorothiazide can be increased when it is combined with Solifenacin.
Chlorthalidone Chlorthalidone The serum concentration of Chlorthalidone can be increased when it is combined with Solifenacin.
Metolazone Metolazone The serum concentration of Metolazone can be increased when it is combined with Solifenacin.
Secobarbital Secobarbital Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Solifenacin.
Amitriptyline Amitriptyline The metabolism of Solifenacin can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Solifenacin.
Quinidine Quinidine The metabolism of Quinidine can be decreased when combined with Solifenacin.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Solifenacin.
Disopyramide Disopyramide The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Disopyramide.
Valproic Acid Valproic Acid The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Solifenacin can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Methimazole Methimazole The metabolism of Solifenacin can be decreased when combined with Methimazole.
Glucagon Injection Glucagon Injection Solifenacin may increase the gastrointestinal motility reducing activities of Glucagon.
Dextromethorphan Dextromethorphan Dextromethorphan may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Cyclobenzaprine Cyclobenzaprine Cyclobenzaprine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Niacin Niacin The metabolism of Solifenacin can be decreased when combined with Niacin.
Baclofen Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Cyproheptadine Cyproheptadine Cyproheptadine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Chlorpheniramine.
Brompheniramine Brompheniramine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Meclizine Meclizine Meclizine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Methyclothiazide Methyclothiazide The serum concentration of Methyclothiazide can be increased when it is combined with Solifenacin.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Hydrochlorothiazide.
Dantrolene Dantrolene Dantrolene may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Chlorzoxazone Chlorzoxazone Chlorzoxazone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Carisoprodol Carisoprodol Carisoprodol may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Methocarbamol Methocarbamol Methocarbamol may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Solifenacin.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Propranolol.
Minoxidil Minoxidil Solifenacin may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine Pseudoephedrine The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Solifenacin.
Nortriptyline Nortriptyline The metabolism of Solifenacin can be decreased when combined with Nortriptyline.
Nadolol Nadolol Solifenacin may decrease the antihypertensive activities of Nadolol.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Solifenacin.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Solifenacin.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Solifenacin.
Trimethobenzamide Trimethobenzamide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Flavoxate Flavoxate The risk or severity of adverse effects can be increased when Flavoxate is combined with Solifenacin.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Fluorouracil.
Acetazolamide Acetazolamide Acetazolamide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ketoconazole Ketoconazole The metabolism of Solifenacin can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel Pyrantel may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Thiotepa Injection Thiotepa Injection The therapeutic efficacy of Solifenacin can be decreased when used in combination with Thiotepa.
Captopril Captopril Solifenacin may decrease the antihypertensive activities of Captopril.
Isoxsuprine Isoxsuprine The risk or severity of hypertension can be increased when Solifenacin is combined with Isoxsuprine.
Vinblastine Vinblastine The metabolism of Solifenacin can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Solifenacin can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Solifenacin.
Thiothixene Thiothixene Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Aspirin Aspirin The risk or severity of hypertension can be increased when Acetylsalicylic acid is combined with Solifenacin.
Salsalate Salsalate The risk or severity of hypertension can be increased when Salsalate is combined with Solifenacin.
Alprazolam Alprazolam Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Temazepam Temazepam Temazepam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Triazolam Triazolam Triazolam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dicyclomine Dicyclomine The risk or severity of adverse effects can be increased when Dicyclomine is combined with Solifenacin.
Hyoscyamine Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Solifenacin.
Propantheline Propantheline The risk or severity of adverse effects can be increased when Propantheline is combined with Solifenacin.
Diltiazem Diltiazem The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Diltiazem.
Nifedipine Nifedipine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Nifedipine.
Timolol Timolol The risk or severity of QTc prolongation can be increased when Timolol is combined with Solifenacin.
Verapamil Verapamil The metabolism of Solifenacin can be decreased when combined with Verapamil.
Atenolol Atenolol Solifenacin may decrease the antihypertensive activities of Atenolol.
Pindolol Pindolol Pindolol may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Cisplatin Injection Cisplatin Injection The therapeutic efficacy of Solifenacin can be decreased when used in combination with Cisplatin.
Diflunisal Diflunisal The risk or severity of hypertension can be increased when Diflunisal is combined with Solifenacin.
Piroxicam Piroxicam The risk or severity of hypertension can be increased when Piroxicam is combined with Solifenacin.
Indapamide Indapamide The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Indapamide.
Pentamidine Injection Pentamidine Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Pentamidine.
Labetalol Labetalol The metabolism of Solifenacin can be decreased when combined with Labetalol.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Leuprolide.
Guanabenz Guanabenz The risk or severity of hypertension can be increased when Guanabenz is combined with Solifenacin.
Ketoprofen Ketoprofen The risk or severity of hypertension can be increased when Ketoprofen is combined with Solifenacin.
Pimozide Pimozide The metabolism of Solifenacin can be decreased when combined with Pimozide.
Enalapril Enalapril Solifenacin may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen The risk or severity of hypertension can be increased when Flurbiprofen is combined with Solifenacin.
Amiodarone Amiodarone The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Solifenacin.
Buspirone Buspirone The risk or severity of hypertension can be increased when Buspirone is combined with Solifenacin.
Lovastatin Lovastatin The metabolism of Solifenacin can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ciprofloxacin.
Mesalamine Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Solifenacin.
Diclofenac Diclofenac The risk or severity of hypertension can be increased when Diclofenac is combined with Solifenacin.
Fluoxetine Fluoxetine The serum concentration of Fluoxetine can be increased when it is combined with Solifenacin.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Nimodipine.
Clozapine Clozapine The metabolism of Clozapine can be decreased when combined with Solifenacin.
Estazolam Estazolam Estazolam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Idarubicin Idarubicin The metabolism of Solifenacin can be decreased when combined with Idarubicin.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ofloxacin.
Clarithromycin Clarithromycin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Clarithromycin.
Benazepril Benazepril Solifenacin may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac The risk or severity of hypertension can be increased when Etodolac is combined with Solifenacin.
Felodipine Felodipine The metabolism of Solifenacin can be decreased when combined with Felodipine.
Fosinopril Fosinopril Solifenacin may decrease the antihypertensive activities of Fosinopril.
Nabumetone Nabumetone The risk or severity of hypertension can be increased when Nabumetone is combined with Solifenacin.
Quinapril Quinapril Solifenacin may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Solifenacin may decrease the antihypertensive activities of Ramipril.
Simvastatin Simvastatin The metabolism of Solifenacin can be decreased when combined with Simvastatin.
Amlodipine Amlodipine Solifenacin may decrease the antihypertensive activities of Amlodipine.
Itraconazole Itraconazole The risk or severity of QTc prolongation can be increased when Itraconazole is combined with Solifenacin.
Lisinopril Lisinopril Solifenacin may decrease the antihypertensive activities of Lisinopril.
Oxaprozin Oxaprozin The risk or severity of hypertension can be increased when Oxaprozin is combined with Solifenacin.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Solifenacin.
Bisoprolol Bisoprolol Solifenacin may decrease the antihypertensive activities of Bisoprolol.
Zolpidem Zolpidem Zolpidem may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Doxazosin Doxazosin Solifenacin may decrease the antihypertensive activities of Doxazosin.
Terazosin Terazosin Solifenacin may decrease the antihypertensive activities of Terazosin.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Isradipine.
Omeprazole Omeprazole The metabolism of Solifenacin can be decreased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Solifenacin.
Gabapentin Gabapentin Gabapentin may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Fluvastatin Fluvastatin The metabolism of Solifenacin can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Solifenacin can be decreased when combined with Venlafaxine.
Nizatidine Nizatidine The therapeutic efficacy of Solifenacin can be decreased when used in combination with Nizatidine.
Fluvoxamine Fluvoxamine The metabolism of Solifenacin can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone Nefazodone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Lamotrigine Lamotrigine Lamotrigine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Losartan Losartan The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Losartan.
Tramadol Tramadol The risk or severity of adverse effects can be increased when Tramadol is combined with Solifenacin.
Vinorelbine Injection Vinorelbine Injection The metabolism of Solifenacin can be decreased when combined with Vinorelbine.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Solifenacin.
Lansoprazole Lansoprazole The metabolism of Solifenacin can be decreased when combined with Lansoprazole.
Nicardipine Nicardipine The metabolism of Solifenacin can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Solifenacin can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Solifenacin can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Saquinavir.
Nisoldipine Nisoldipine Solifenacin may decrease the antihypertensive activities of Nisoldipine.
Riluzole Riluzole Riluzole may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Ritonavir Ritonavir The serum concentration of Solifenacin can be increased when it is combined with Ritonavir.
Clomipramine Clomipramine The metabolism of Solifenacin can be decreased when combined with Clomipramine.
Mirtazapine Mirtazapine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Trandolapril Trandolapril Solifenacin may decrease the antihypertensive activities of Trandolapril.
Topiramate Topiramate The risk or severity of hyperthermia and oligohydrosis can be increased when Solifenacin is combined with Topiramate.
Valsartan Valsartan Solifenacin may decrease the antihypertensive activities of Valsartan.
Donepezil Donepezil The therapeutic efficacy of Solifenacin can be decreased when used in combination with Donepezil.
Nelfinavir Nelfinavir The metabolism of Solifenacin can be decreased when combined with Nelfinavir.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Azithromycin.
Loratadine Loratadine Solifenacin may increase the anticholinergic activities of Loratadine.
Carvedilol Carvedilol Solifenacin may decrease the antihypertensive activities of Carvedilol.
Selegiline Selegiline Selegiline may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Bicalutamide Bicalutamide The metabolism of Solifenacin can be decreased when combined with Bicalutamide.
Sertraline Sertraline Sertraline may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Propafenone Propafenone The metabolism of Solifenacin can be decreased when combined with Propafenone.
Irbesartan Irbesartan Solifenacin may decrease the antihypertensive activities of Irbesartan.
Tamsulosin Tamsulosin The metabolism of Solifenacin can be decreased when combined with Tamsulosin.
Ropinirole Ropinirole Ropinirole may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Finasteride Finasteride The risk or severity of hypertension can be increased when Finasteride is combined with Solifenacin.
Quetiapine Quetiapine The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Quetiapine.
Cetirizine Cetirizine Cetirizine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Paroxetine Paroxetine The metabolism of Solifenacin can be decreased when combined with Paroxetine.
Tolcapone Tolcapone Tolcapone may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Citalopram Citalopram The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Citalopram.
Efavirenz Efavirenz The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Efavirenz.
Sildenafil Sildenafil The metabolism of Solifenacin can be decreased when combined with Sildenafil.
Celecoxib Celecoxib The metabolism of Solifenacin can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Solifenacin can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Solifenacin.
Thalidomide Thalidomide Thalidomide may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Balsalazide Balsalazide The risk or severity of hypertension can be increased when Balsalazide is combined with Solifenacin.
Nateglinide Nateglinide The metabolism of Solifenacin can be decreased when combined with Nateglinide.
Galantamine Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Solifenacin.
Levetiracetam Levetiracetam Levetiracetam may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Rabeprazole Rabeprazole The metabolism of Solifenacin can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Solifenacin can be decreased when combined with Terbinafine.

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