Amantadine

Generic name: Pronounced as (a man' ta deen)
Brand names
  • Gocovri®
  • Osmolex ER®
  • Symadine®
  • Symmetrel®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 06/15/2021

Amantadine is used to treat the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) and other similar conditions. It is also used to control movement problems that are a side effect of certain medications used to treat Parkinson's disease. Amantadine extended-release capsules (Gocovri) are used along with the combination of levodopa and carbidopa (Rytary, Sinemet) to treat ''off'' episodes (times of difficulty moving, walking, and speaking that may happen when other medications wear off) in people with Parkinson's disease. It also is used to prevent symptoms of influenza A virus infection and for treatment of respiratory infections caused by influenza A virus. Amantadine is in a class of medications called adamantanes. It is thought to work to control movement problems by increasing the amount of dopamine in certain parts of the body. It works against influenza A virus by stopping the spread of the virus in the body.

Amantadine comes as a capsule, extended-release capsule (Gocovri), tablet, extended-release tablet (Osmolex), and liquid to take by mouth. The capsules, tablets, and liquid medications are usually taken once or twice a day. The extended-release capsules are usually taken once a day at bedtime. The extended-release tablets are usually taken once a day in the morning. Take amantadine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amantadine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release capsules and extended-release tablets whole; do not split, chew, or crush them. If you have difficulty swallowing the extended-release capsule, you may open the capsule and sprinkle the entire contents on a teaspoonful of soft food, like applesauce. Eat the mixture right away and swallow without chewing.

If you are taking amantadine for Parkinson's disease, your doctor may start you on a low dose of amantadine and gradually increase your dose.

Do not stop taking amantadine without talking to your doctor. If you suddenly stop taking amantadine, you may experience fever, confusion, changes in mental state, or severe muscle stiffness. Your doctor will probably decrease your dose gradually.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking amantadine,

  • tell your doctor and pharmacist if you are allergic to amantadine, any other medications, or any of the ingredients in amantadine capsules, extended-release capsules, tablets, extended-release tablets, or liquid. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: acetazolamide; antihistamines; dichlorphenamide; hydrochlorothiazide with triamterene (Maxzide, Dyrenium); medications for mental illness, motion sickness, sleep, or urinary problems; other medications to treat Parkinson's disease; methazolamide; quinine (Qualaquin); quinidine (in Nuedexta); sedatives; sodium bicarbonate (Alka-Seltzer, in Zegerid); stimulants; or thioridazine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with amantadine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have kidney disease. Your doctor may tell you not to take amantadine.

  • tell your doctor if you drink or have ever drunk large amounts of alcohol, use or have ever used street drugs, or have overused prescription medications or if you have or have ever had depression, unusual changes in behavior or mood, mental illness, or thoughts about or attempted suicide; epilepsy or any other type of seizures; a sleep disorder; urinary tract infections; glaucoma (a condition in which increased pressure in the eye can lead to gradual loss of vision); eczema (atopic dermatitis; a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes); heart failure; swelling of the hands, feet, ankles, or lower legs; low blood pressure; or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking amantadine, call your doctor immediately. Amantadine may cause harm to the fetus.

  • you should know that amantadine may make you drowsy or cause blurred vision. Do not drive a car, operate machinery, or participate in potentially dangerous activities until you know how this medication affects you.

  • you should know that amantadine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking amantadine or if your dose has been increased. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

  • do not have any vaccinations without talking to your doctor.

  • you should know that some people taking amantadine and other similar medications used to treat Parkinson's disease, have developed gambling problems or had other intense urges or behaviors that were compulsive or unusual for them, such as increased sexual urges, binge eating, or uncontrolled spending. Call your doctor if you have an urge to gamble that is difficult to control, you have intense urges, or you are unable to control your behavior. Tell your family members about this risk so that they can call the doctor even if you do not realize that your gambling or any other intense urges or unusual behaviors have become a problem.

Unless your doctor tells you otherwise, continue your normal diet.

If you are taking the capsules, tablets, or liquid, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

If you are taking the extended-release capsules or the extended-release tablets, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have forgotten to take the extended-release capsules or extended-release tablets for several days, call your doctor.

  • Amantadine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • dry mouth

    • constipation

    • nausea

    • vomiting

    • decreased appetite

    • difficulty falling asleep or staying asleep

    • abnormal dreams

    • headache

    • confusion

    • drowsiness

    • tiredness

    • uncontrollable tightening of muscles, change from normal walking, and falls

    • lace-like purple pattern on skin

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • hallucinations (seeing things or hearing voices that do not exist)

    • believing things that are not true

    • not trusting others or feeling that others want to hurt you

    • depression

    • anxiety

    • suicidal (thinking about harming or killing oneself or planning or trying to do so)

    • lack of interest, enthusiasm, or concern

    • dizziness, lightheadedness, fainting, or blurred vision

    • swelling of the hands, feet, ankles, or lower legs

    • difficulty urinating

    • shortness of breath

  • Amantadine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • irregular or fast heartbeat

  • difficulty breathing

  • decreased urination

  • swelling of the hands, feet, ankles or lower legs

  • stiff or rigid arms or legs

  • uncontrollable movements or shaking of a part of the body

  • problems with coordination

  • confusion

  • feeling like you are looking at yourself as an outside observer

  • fear, irritability, or aggressive behavior

  • seeing things or hearing voices that do not exist

  • lack of energy

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to amantadine.

If you are taking the extended-release tablets (Osmolex), you may notice something that looks like a tablet in your stool. This is just the empty tablet shell, and does not mean that you did not get your complete dose of medication.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Adamantanamine Hydrochloride

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Amantadine is combined with Moxifloxacin.
Nevirapine Nevirapine The risk or severity of adverse effects can be increased when Nevirapine is combined with Amantadine.
Dolasetron Dolasetron The risk or severity of serotonin syndrome can be increased when Dolasetron is combined with Amantadine.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Amantadine is combined with Anagrelide.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Amantadine.
Cilostazol Cilostazol The risk or severity of QTc prolongation can be increased when Amantadine is combined with Cilostazol.
Clopidogrel Clopidogrel The serum concentration of Amantadine can be increased when it is combined with Clopidogrel.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Amantadine is combined with Diphenoxylate.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Amantadine is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the excretion rate of Amantadine which could result in a higher serum level.
Fenofibrate Fenofibrate Amantadine may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Amantadine is combined with Guanfacine.
Magnesium Hydroxide Magnesium Hydroxide Amantadine may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Magnesium Oxide Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Amantadine.
Mycophenolate Mycophenolate Amantadine may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Naratriptan Naratriptan The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Naratriptan.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Amantadine.
Penbutolol Penbutolol The risk or severity of QTc prolongation can be increased when Amantadine is combined with Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Amantadine.
Polyethylene glycol-electrolyte solution (PEG-ES) Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Amantadine.
Potassium Potassium Potassium may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone Prednisone may decrease the excretion rate of Amantadine which could result in a higher serum level.
Psyllium Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Amantadine.
Ranitidine Ranitidine The serum concentration of Amantadine can be increased when it is combined with Ranitidine.
Reserpine Reserpine The serum concentration of Reserpine can be increased when it is combined with Amantadine.
Rizatriptan Rizatriptan The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of serotonin syndrome can be increased when Sumatriptan is combined with Amantadine.
Tacrolimus Tacrolimus Tacrolimus may decrease the excretion rate of Amantadine which could result in a higher serum level.
Tizanidine Tizanidine The risk or severity of QTc prolongation can be increased when Tizanidine is combined with Amantadine.
Zolmitriptan Zolmitriptan The risk or severity of serotonin syndrome can be increased when Zolmitriptan is combined with Amantadine.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Doxycycline may decrease the excretion rate of Amantadine which could result in a higher serum level.
Famotidine Injection Famotidine Injection The serum concentration of Amantadine can be increased when it is combined with Famotidine.
Fluconazole Injection Fluconazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Amantadine.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Amantadine which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Amantadine.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Levofloxacin.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Amantadine is combined with Meperidine.
Metoclopramide Injection Metoclopramide Injection The therapeutic efficacy of Amantadine can be decreased when used in combination with Metoclopramide.
Metronidazole Injection Metronidazole Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Metronidazole.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Amantadine.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Amantadine which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Amantadine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine Altretamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Amantadine.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cyclosporine Cyclosporine Cyclosporine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Ondansetron Ondansetron The risk or severity of serotonin syndrome can be increased when Ondansetron is combined with Amantadine.
Granisetron Granisetron The risk or severity of serotonin syndrome can be increased when Granisetron is combined with Amantadine.
Torsemide Torsemide Torasemide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Olanzapine Olanzapine The therapeutic efficacy of Amantadine can be decreased when used in combination with Olanzapine.
Dofetilide Dofetilide The serum concentration of Dofetilide can be increased when it is combined with Amantadine.
Hydroxychloroquine Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Hydroxychloroquine.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Amantadine which could result in a higher serum level.
Temozolomide Temozolomide Temozolomide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Zaleplon Zaleplon Amantadine may decrease the excretion rate of Zaleplon which could result in a higher serum level.
Desloratadine Desloratadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Desloratadine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Amantadine.
Rivastigmine Rivastigmine The therapeutic efficacy of Amantadine can be decreased when used in combination with Rivastigmine.
Trimipramine Trimipramine The risk or severity of serotonin syndrome can be increased when Trimipramine is combined with Amantadine.
Glycopyrrolate Glycopyrrolate Amantadine may increase the anticholinergic activities of Glycopyrronium.
Perindopril Perindopril Perindopril may decrease the excretion rate of Amantadine which could result in a higher serum level.
Tenofovir Tenofovir Tenofovir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Amantadine which could result in a higher serum level.
Epinephrine Injection Epinephrine Injection The serum concentration of Amantadine can be increased when it is combined with Epinephrine.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Escitalopram.
Zonisamide Zonisamide Zonisamide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Aripiprazole Aripiprazole The therapeutic efficacy of Amantadine can be decreased when used in combination with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of QTc prolongation can be increased when Atomoxetine is combined with Amantadine.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Dexmethylphenidate is combined with Amantadine.
Atazanavir Atazanavir Atazanavir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Almotriptan Almotriptan The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Almotriptan.
Eletriptan Eletriptan The risk or severity of serotonin syndrome can be increased when Eletriptan is combined with Amantadine.
Mefloquine Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Amantadine.
Polyethylene Glycol 3350 Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Amantadine.
Vardenafil Vardenafil The risk or severity of QTc prolongation can be increased when Vardenafil is combined with Amantadine.
Alfuzosin Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Amantadine.
Emtricitabine Emtricitabine Emtricitabine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Memantine Memantine The risk or severity of adverse effects can be increased when Amantadine is combined with Memantine.
Tegaserod Tegaserod The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Tegaserod.
Tadalafil Tadalafil Tadalafil may decrease the excretion rate of Amantadine which could result in a higher serum level.
Frovatriptan Frovatriptan The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Frovatriptan.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Amantadine is combined with Gemifloxacin.
Progesterone Progesterone The serum concentration of Amantadine can be increased when it is combined with Progesterone.
Apomorphine Injection Apomorphine Injection The risk or severity of serotonin syndrome can be increased when Apomorphine is combined with Amantadine.
Protriptyline Protriptyline The risk or severity of serotonin syndrome can be increased when Protriptyline is combined with Amantadine.
Duloxetine Duloxetine The risk or severity of serotonin syndrome can be increased when Duloxetine is combined with Amantadine.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Amantadine which could result in a higher serum level.
Trospium Trospium The risk or severity of adverse effects can be increased when Trospium is combined with Amantadine.
Cefditoren Cefditoren Cefdinir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Erlotinib Erlotinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Erlotinib.
Eszopiclone Eszopiclone Eszopiclone may decrease the excretion rate of Amantadine which could result in a higher serum level.
Ganciclovir Ganciclovir The risk or severity of adverse effects can be increased when Amantadine is combined with Ganciclovir.
Ribavirin Ribavirin Ribavirin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Solifenacin Solifenacin The risk or severity of QTc prolongation can be increased when Amantadine is combined with Solifenacin.
Valganciclovir Valganciclovir Amantadine may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Voriconazole Voriconazole The risk or severity of QTc prolongation can be increased when Voriconazole is combined with Amantadine.
Adefovir Adefovir Adefovir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Amantadine.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Amantadine.
Isocarboxazid Isocarboxazid The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Isocarboxazid.
Ramelteon Ramelteon Amantadine may decrease the excretion rate of Ramelteon which could result in a higher serum level.
Darifenacin Darifenacin The risk or severity of adverse effects can be increased when Darifenacin is combined with Amantadine.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Amantadine is combined with Fentanyl.
Pregabalin Pregabalin The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Amantadine.
Felbamate Felbamate The risk or severity of QTc prolongation can be increased when Amantadine is combined with Felbamate.
Ranolazine Ranolazine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ranolazine.
Rasagiline Rasagiline The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Rasagiline.
Imatinib Imatinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Imatinib.
Sitagliptin Sitagliptin Amantadine may decrease the excretion rate of Sitagliptin which could result in a higher serum level.
Varenicline Varenicline The excretion of Varenicline can be decreased when combined with Amantadine.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Amantadine is combined with Salbutamol.
Paliperidone Paliperidone The risk or severity of QTc prolongation can be increased when Amantadine is combined with Paliperidone.
Bortezomib Bortezomib The risk or severity of QTc prolongation can be increased when Bortezomib is combined with Amantadine.
Clofarabine Injection Clofarabine Injection The serum concentration of Amantadine can be increased when it is combined with Clofarabine.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Amantadine.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The therapeutic efficacy of Varicella Zoster Vaccine (Live/attenuated) can be decreased when used in combination with Amantadine.
Lubiprostone Lubiprostone Amantadine may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection The serum concentration of Oxaliplatin can be increased when it is combined with Amantadine.
Posaconazole Posaconazole The risk or severity of QTc prolongation can be increased when Amantadine is combined with Posaconazole.
Primaquine Primaquine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Primaquine.
Pemetrexed Injection Pemetrexed Injection Amantadine may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Dimenhydrinate Dimenhydrinate The risk or severity of QTc prolongation can be increased when Amantadine is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Lisdexamfetamine.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Amantadine is combined with Vorinostat.
Sorafenib Sorafenib The risk or severity of QTc prolongation can be increased when Sorafenib is combined with Amantadine.
Sunitinib Sunitinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Sunitinib.
Lapatinib Lapatinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Lapatinib.
Levocetirizine Levocetirizine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Levocetirizine.
Pegaptanib Injection Pegaptanib Injection Amantadine may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Dasatinib Dasatinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Dasatinib.
Azacitidine Injection Azacitidine Injection Amantadine may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Paclitaxel (with polyoxyethylated castor oil) Injection Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Amantadine.
Lenalidomide Lenalidomide Lenalidomide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Nilotinib Nilotinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Nilotinib.
Toremifene Toremifene The risk or severity of QTc prolongation can be increased when Amantadine is combined with Toremifene.
Budesonide Budesonide Amantadine may decrease the excretion rate of Budesonide which could result in a higher serum level.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Betaine Betaine The therapeutic efficacy of Amantadine can be decreased when used in combination with Glycine betaine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Amantadine is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Amantadine is combined with Botulinum Toxin Type B.
Doripenem Injection Doripenem Injection Amantadine may decrease the excretion rate of Doripenem which could result in a higher serum level.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Desvenlafaxine.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Amantadine which could result in a higher serum level.
Flecainide Flecainide The risk or severity of QTc prolongation can be increased when Amantadine is combined with Flecainide.
Certolizumab Injection Certolizumab Injection Amantadine may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Amantadine may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Midazolam Midazolam Midazolam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Naltrexone Injection Naltrexone Injection The risk or severity of adverse effects can be increased when Naltrexone is combined with Amantadine.
Dexrazoxane Injection Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Amantadine which could result in a higher serum level.
Milnacipran Milnacipran The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Milnacipran.
Plerixafor Injection Plerixafor Injection Amantadine may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Sodium Phosphate Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Amantadine.
Fesoterodine Fesoterodine Amantadine may decrease the excretion rate of Fesoterodine which could result in a higher serum level.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Degarelix.
Betaxolol Betaxolol The risk or severity of QTc prolongation can be increased when Amantadine is combined with Betaxolol.
Iloperidone Iloperidone The risk or severity of QTc prolongation can be increased when Amantadine is combined with Iloperidone.
Prasugrel Prasugrel Amantadine may decrease the excretion rate of Prasugrel which could result in a higher serum level.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone Dronedarone The risk or severity of QTc prolongation can be increased when Amantadine is combined with Dronedarone.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Amantadine is combined with Botulinum toxin type A.
Pralatrexate Injection Pralatrexate Injection Amantadine may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The risk or severity of serotonin syndrome can be increased when Palonosetron is combined with Amantadine.
Saxagliptin Saxagliptin Amantadine may decrease the excretion rate of Saxagliptin which could result in a higher serum level.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Romidepsin.
Tapentadol Tapentadol The risk or severity of adverse effects can be increased when Amantadine is combined with Tapentadol.
Topotecan Topotecan Amantadine may decrease the excretion rate of Topotecan which could result in a higher serum level.
Pazopanib Pazopanib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Pazopanib.
Asenapine Asenapine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Asenapine.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Amantadine is combined with Oxymorphone.
Dalfampridine Dalfampridine The serum concentration of Dalfampridine can be increased when it is combined with Amantadine.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Eribulin.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Amantadine is combined with Botulinum toxin type A.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Amantadine which could result in a higher serum level.
Lurasidone Lurasidone The therapeutic efficacy of Amantadine can be decreased when used in combination with Lurasidone.
Acetaminophen Injection Acetaminophen Injection Acetaminophen may decrease the excretion rate of Amantadine which could result in a higher serum level.
Vilazodone Vilazodone The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Vilazodone.
Ipilimumab Injection Ipilimumab Injection Amantadine may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Amantadine.
Roflumilast Roflumilast Amantadine may decrease the excretion rate of Roflumilast which could result in a higher serum level.
Linagliptin Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Amantadine.
Rilpivirine Rilpivirine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Rilpivirine.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Triptorelin.
Rivaroxaban Rivaroxaban Amantadine may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ruxolitinib Ruxolitinib Amantadine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Vandetanib Vandetanib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Vandetanib.
Clobazam Clobazam Clobazam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Vemurafenib Vemurafenib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Vemurafenib.
Deferiprone Deferiprone Amantadine may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Crizotinib Crizotinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Crizotinib.
Cabergoline Cabergoline The risk or severity of serotonin syndrome can be increased when Cabergoline is combined with Amantadine.
Naloxone Injection Naloxone Injection Amantadine may decrease the excretion rate of Naloxone which could result in a higher serum level.
Fondaparinux Injection Fondaparinux Injection Fondaparinux may decrease the excretion rate of Amantadine which could result in a higher serum level.
Enzalutamide Enzalutamide Amantadine may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
Mirabegron Mirabegron The risk or severity of QTc prolongation can be increased when Amantadine is combined with Mirabegron.
Linaclotide Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Amantadine.
Teduglutide Injection Teduglutide Injection Amantadine may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Amantadine is combined with Bedaquiline.
Alogliptin Alogliptin Amantadine may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Pomalidomide Pomalidomide Amantadine may decrease the excretion rate of Pomalidomide which could result in a higher serum level.
Canagliflozin Canagliflozin Amantadine may increase the excretion rate of Canagliflozin which could result in a lower serum level and potentially a reduction in efficacy.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Dabrafenib.
Trametinib Trametinib Amantadine may decrease the excretion rate of Trametinib which could result in a higher serum level.
Dolutegravir Dolutegravir The serum concentration of Amantadine can be increased when it is combined with Dolutegravir.
Levomilnacipran Levomilnacipran The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Levomilnacipran.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Amantadine which could result in a higher serum level.
Vortioxetine Vortioxetine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Vortioxetine.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Amantadine which could result in a higher serum level.
Sofosbuvir Sofosbuvir Amantadine may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast Amantadine may decrease the excretion rate of Apremilast which could result in a higher serum level.
Droxidopa Droxidopa Amantadine may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Ceritinib Ceritinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ceritinib.
Testosterone Injection Testosterone Injection Testosterone may decrease the excretion rate of Amantadine which could result in a higher serum level.
Hydrocodone Hydrocodone The risk or severity of serotonin syndrome can be increased when Hydrocodone is combined with Amantadine.
Edoxaban Edoxaban Amantadine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methamphetamine Methamphetamine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Metamfetamine.
Tasimelteon Tasimelteon Amantadine may decrease the excretion rate of Tasimelteon which could result in a higher serum level.
Risperidone Injection Risperidone Injection The therapeutic efficacy of Amantadine can be decreased when used in combination with Risperidone.
Palbociclib Palbociclib The risk or severity of adverse effects can be increased when Palbociclib is combined with Amantadine.
Lenvatinib Lenvatinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Lenvatinib.
Panobinostat Panobinostat The risk or severity of QTc prolongation can be increased when Amantadine is combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Haloperidol.
Ivabradine Ivabradine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ivabradine.
Amiloride Amiloride The serum concentration of Amantadine can be increased when it is combined with Amiloride.
Macitentan Macitentan Amantadine may decrease the excretion rate of Macitentan which could result in a higher serum level.
Flibanserin Flibanserin The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Flibanserin.
Brexpiprazole Brexpiprazole The therapeutic efficacy of Amantadine can be decreased when used in combination with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ziprasidone.
Cariprazine Cariprazine The therapeutic efficacy of Amantadine can be decreased when used in combination with Cariprazine.
Penicillin G Procaine Injection Penicillin G Procaine Injection Amantadine may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Eluxadoline Eluxadoline The risk or severity of constipation can be increased when Amantadine is combined with Eluxadoline.
Ixazomib Ixazomib Amantadine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lesinurad Lesinurad Amantadine may decrease the excretion rate of Lesinurad which could result in a higher serum level.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Amantadine which could result in a higher serum level.
Brivaracetam Injection Brivaracetam Injection Amantadine may decrease the excretion rate of Brivaracetam which could result in a higher serum level.
Pimavanserin Pimavanserin The therapeutic efficacy of Amantadine can be decreased when used in combination with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The serum concentration of Diphenhydramine can be increased when it is combined with Amantadine.
Furosemide Injection Furosemide Injection Furosemide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib Rucaparib The risk or severity of adverse effects can be increased when Rucaparib is combined with Amantadine.
Lixisenatide Injection Lixisenatide Injection Amantadine may decrease the excretion rate of Lixisenatide which could result in a higher serum level.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ribociclib.
Doxepin (Insomnia) Doxepin (Insomnia) The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Doxepin.
Plecanatide Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Amantadine.
Deutetrabenazine Deutetrabenazine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Deutetrabenazine.
Valbenazine Valbenazine Amantadine may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Safinamide Safinamide The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Safinamide.
Naldemedine Naldemedine Amantadine may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Enasidenib Enasidenib The serum concentration of Amantadine can be increased when it is combined with Enasidenib.
Benznidazole Benznidazole Amantadine may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin The risk or severity of QTc prolongation can be increased when Amantadine is combined with Delafloxacin.
Tetrabenazine Tetrabenazine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Tetrabenazine.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Buprenorphine Injection Buprenorphine Injection The risk or severity of adverse effects can be increased when Amantadine is combined with Buprenorphine.
Apalutamide Apalutamide The serum concentration of Amantadine can be increased when it is combined with Apalutamide.
Baricitinib Baricitinib The serum concentration of Amantadine can be increased when it is combined with Baricitinib.
Lofexidine Lofexidine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Lofexidine.
Plazomicin Injection Plazomicin Injection Amantadine may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Eliglustat Eliglustat The risk or severity of QTc prolongation can be increased when Amantadine is combined with Eliglustat.
Encorafenib Encorafenib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Encorafenib.
Ivosidenib Ivosidenib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ivosidenib.
Tafenoquine Tafenoquine The serum concentration of Amantadine can be increased when it is combined with Tafenoquine.
Cannabidiol Cannabidiol The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Cannabidiol.
Dacomitinib Dacomitinib The risk or severity of adverse effects can be increased when Dacomitinib is combined with Amantadine.
Stiripentol Stiripentol Amantadine may decrease the excretion rate of Stiripentol which could result in a higher serum level.
Gilteritinib Gilteritinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Gilteritinib.
Glasdegib Glasdegib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Glasdegib.
Prucalopride Prucalopride Amantadine may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Magnesium Citrate Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Amantadine.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Erdafitinib Erdafitinib The serum concentration of Amantadine can be increased when it is combined with Erdafitinib.
Solriamfetol Solriamfetol The serum concentration of Solriamfetol can be increased when it is combined with Amantadine.
Triclabendazole Triclabendazole The risk or severity of QTc prolongation can be increased when Amantadine is combined with Triclabendazole.
Entrectinib Entrectinib The risk or severity of QTc prolongation can be increased when Amantadine is combined with Entrectinib.
Pitolisant Pitolisant Amantadine may increase the QTc-prolonging activities of Pitolisant.
Lefamulin Lefamulin Lefamulin may increase the QTc-prolonging activities of Amantadine.
Lumateperone Lumateperone The therapeutic efficacy of Amantadine can be decreased when used in combination with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Lasmiditan.
Tucatinib Tucatinib The serum concentration of Amantadine can be increased when it is combined with Tucatinib.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Amantadine.
Fostemsavir Fostemsavir The risk or severity of QTc prolongation can be increased when Amantadine is combined with Fostemsavir.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Amantadine.
Relugolix Relugolix The risk or severity of QTc prolongation can be increased when Amantadine is combined with Relugolix.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Viloxazine Viloxazine Amantadine may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Amantadine which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Amantadine which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Amantadine which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Amantadine which could result in a higher serum level.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Amantadine.
Isotretinoin Isotretinoin Amantadine may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Amantadine which could result in a higher serum level.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Amantadine is combined with Phenobarbital.
Metaxalone Metaxalone The risk or severity of serotonin syndrome can be increased when Metaxalone is combined with Amantadine.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Amantadine which could result in a higher serum level.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Amantadine.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Amantadine.
Methsuximide Methsuximide The risk or severity of QTc prolongation can be increased when Amantadine is combined with Methsuximide.
Diethylpropion Diethylpropion The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The therapeutic efficacy of Amantadine can be decreased when used in combination with Chlorpromazine.
Diazepam Diazepam Diazepam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Oxazepam Oxazepam Oxazepam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Flurazepam Flurazepam The serum concentration of Amantadine can be increased when it is combined with Flurazepam.
Clorazepate Clorazepate Clorazepic acid may decrease the excretion rate of Amantadine which could result in a higher serum level.
Lorazepam Lorazepam Lorazepam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Phenoxybenzamine Phenoxybenzamine The serum concentration of Amantadine can be increased when it is combined with Phenoxybenzamine.
Carmustine Carmustine Carmustine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine Codeine The risk or severity of adverse effects can be increased when Amantadine is combined with Codeine.
Tranylcypromine Tranylcypromine The risk or severity of serotonin syndrome can be increased when Tranylcypromine is combined with Amantadine.
Phenelzine Phenelzine The risk or severity of serotonin syndrome can be increased when Phenelzine is combined with Amantadine.
Procarbazine Procarbazine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Ergoloid mesylate.
Tetracycline Tetracycline Tetracycline may decrease the excretion rate of Amantadine which could result in a higher serum level.
Prochlorperazine Prochlorperazine The therapeutic efficacy of Amantadine can be decreased when used in combination with Prochlorperazine.
Thioridazine Thioridazine The therapeutic efficacy of Thioridazine can be decreased when used in combination with Amantadine.
Trifluoperazine Trifluoperazine The therapeutic efficacy of Amantadine can be decreased when used in combination with Trifluoperazine.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Sulfadiazine Sulfadiazine Sulfadiazine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Amantadine.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Amantadine.
Oxybutynin Oxybutynin The risk or severity of adverse effects can be increased when Amantadine is combined with Oxybutynin.
Benztropine Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Amantadine.
Maprotiline Maprotiline The risk or severity of QTc prolongation can be increased when Amantadine is combined with Maprotiline.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Amantadine which could result in a higher serum level.
Trihexyphenidyl Trihexyphenidyl The risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Amantadine.
Orphenadrine Orphenadrine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Orphenadrine.
Perphenazine Perphenazine The therapeutic efficacy of Amantadine can be decreased when used in combination with Perphenazine.
Azathioprine Azathioprine Amantadine may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Fluphenazine Fluphenazine The therapeutic efficacy of Amantadine can be decreased when used in combination with Fluphenazine.
Phentermine Phentermine The risk or severity of serotonin syndrome can be increased when Phentermine is combined with Amantadine.
Methylphenidate Methylphenidate The risk or severity of adverse effects can be increased when Methylphenidate is combined with Amantadine.
Amoxapine Amoxapine The risk or severity of serotonin syndrome can be increased when Amoxapine is combined with Amantadine.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Amantadine is combined with Cytarabine.
Mechlorethamine Mechlorethamine The therapeutic efficacy of Amantadine can be decreased when used in combination with Mechlorethamine.
Pyridostigmine Pyridostigmine The therapeutic efficacy of Amantadine can be decreased when used in combination with Pyridostigmine.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Carbamazepine Carbamazepine Amantadine may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
Molindone Molindone The therapeutic efficacy of Amantadine can be decreased when used in combination with Molindone.
Methyldopa Methyldopa Amantadine may decrease the excretion rate of Methyldopa which could result in a higher serum level.
Prazosin Prazosin The serum concentration of Prazosin can be increased when it is combined with Amantadine.
Hydralazine Hydralazine Amantadine may decrease the excretion rate of Hydralazine which could result in a higher serum level.
Cimetidine Cimetidine The serum concentration of Amantadine can be increased when it is combined with Cimetidine.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Warfarin Warfarin Amantadine may decrease the excretion rate of Warfarin which could result in a higher serum level.
Clonazepam Clonazepam Amantadine may decrease the excretion rate of Clonazepam which could result in a higher serum level.
Loperamide Loperamide The risk or severity of QTc prolongation can be increased when Amantadine is combined with Loperamide.
Promethazine Promethazine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Promethazine.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Amantadine which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Digoxin Digoxin Amantadine may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine Loxapine The therapeutic efficacy of Amantadine can be decreased when used in combination with Loxapine.
Chloroquine Chloroquine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Chloroquine.
Quinine Quinine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of QTc prolongation can be increased when Ethosuximide is combined with Amantadine.
Triamterene Triamterene Triamterene may decrease the excretion rate of Amantadine which could result in a higher serum level.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Amantadine.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Metolazone may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital Secobarbital may decrease the excretion rate of Amantadine which could result in a higher serum level.
Desipramine Desipramine The serum concentration of Desipramine can be increased when it is combined with Amantadine.
Amitriptyline Amitriptyline The risk or severity of serotonin syndrome can be increased when Amitriptyline is combined with Amantadine.
Imipramine Imipramine The risk or severity of QTc prolongation can be increased when Imipramine is combined with Amantadine.
Probenecid Probenecid The serum concentration of Amantadine can be increased when it is combined with Probenecid.
Quinidine Quinidine Quinidine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Procainamide Procainamide The serum concentration of Procainamide can be increased when it is combined with Amantadine.
Isoniazid Isoniazid The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Isoniazid.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Disopyramide Disopyramide The risk or severity of QTc prolongation can be increased when Disopyramide is combined with Amantadine.
Valproic Acid Valproic Acid The risk or severity of QTc prolongation can be increased when Amantadine is combined with Valproic acid.
Tamoxifen Tamoxifen The risk or severity of QTc prolongation can be increased when Tamoxifen is combined with Amantadine.
Butabarbital Butabarbital Butabarbital may decrease the excretion rate of Amantadine which could result in a higher serum level.
Liothyronine Liothyronine Liothyronine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Methimazole Methimazole Methimazole may decrease the excretion rate of Amantadine which could result in a higher serum level.
Chlorpropamide Chlorpropamide Chlorpropamide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Tolbutamide Tolbutamide Amantadine may decrease the excretion rate of Tolbutamide which could result in a higher serum level.
Tolazamide Tolazamide Tolazamide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Dextromethorphan Dextromethorphan The risk or severity of serotonin syndrome can be increased when Dextromethorphan is combined with Amantadine.
Dinoprostone Dinoprostone The serum concentration of Amantadine can be increased when it is combined with Dinoprostone.
Cyclobenzaprine Cyclobenzaprine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Cyclobenzaprine.
Baclofen Baclofen Baclofen may decrease the excretion rate of Amantadine which could result in a higher serum level.
Doxylamine Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Amantadine.
Cyproheptadine Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Amantadine.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Amantadine.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Amantadine which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Chlorzoxazone Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Amantadine which could result in a higher serum level.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Amantadine which could result in a higher serum level.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Amantadine.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The risk or severity of QTc prolongation can be increased when Amantadine is combined with Propranolol.
Pseudoephedrine Pseudoephedrine The risk or severity of serotonin syndrome can be increased when Pseudoephedrine is combined with Amantadine.
Nortriptyline Nortriptyline The risk or severity of serotonin syndrome can be increased when Nortriptyline is combined with Amantadine.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Amantadine which could result in a higher serum level.
Phytonadione Phytonadione Amantadine may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Nadolol Nadolol Amantadine may decrease the excretion rate of Nadolol which could result in a higher serum level.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Amantadine.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Amantadine.
Allopurinol Allopurinol Allopurinol may decrease the excretion rate of Amantadine which could result in a higher serum level.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Amantadine.
Flavoxate Flavoxate Amantadine may decrease the excretion rate of Flavoxate which could result in a higher serum level.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Fluorouracil.
Colchicine Colchicine Amantadine may decrease the excretion rate of Colchicine which could result in a higher serum level.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Dacarbazine Dacarbazine Dacarbazine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Acetazolamide Acetazolamide Acetazolamide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Amantadine which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The therapeutic efficacy of Bacillus calmette-guerin substrain tice live antigen can be decreased when used in combination with Amantadine.
Ketoconazole Ketoconazole The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ketoconazole.
Pyrantel Pyrantel Amantadine may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Thiotepa Injection Thiotepa Injection The therapeutic efficacy of Amantadine can be decreased when used in combination with Thiotepa.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Amantadine which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Amantadine which could result in a higher serum level.
Metoprolol Metoprolol The serum concentration of Amantadine can be increased when it is combined with Metoprolol.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Amantadine.
Thiothixene Thiothixene The therapeutic efficacy of Amantadine can be decreased when used in combination with Thiothixene.
Aspirin Aspirin Acetylsalicylic acid may decrease the excretion rate of Amantadine which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Amantadine which could result in a higher serum level.
Alprazolam Alprazolam Alprazolam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Temazepam Temazepam Temazepam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Triazolam Triazolam Triazolam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Dicyclomine Dicyclomine Dicyclomine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Hyoscyamine Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Amantadine.
Propantheline Propantheline Propantheline may decrease the excretion rate of Amantadine which could result in a higher serum level.
Trimethoprim Trimethoprim The serum concentration of Amantadine can be increased when it is combined with Trimethoprim.
Diltiazem Diltiazem The risk or severity of QTc prolongation can be increased when Amantadine is combined with Diltiazem.
Nifedipine Nifedipine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Nifedipine.
Timolol Timolol The risk or severity of QTc prolongation can be increased when Timolol is combined with Amantadine.
Verapamil Verapamil The risk or severity of adverse effects can be increased when Verapamil is combined with Amantadine.
Pindolol Pindolol The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Pindolol.
Cisplatin Injection Cisplatin Injection The serum concentration of Amantadine can be increased when it is combined with Cisplatin.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Amantadine which could result in a higher serum level.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Bumetanide Bumetanide Bumetanide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Glipizide Glipizide Amantadine may decrease the excretion rate of Glipizide which could result in a higher serum level.
Indapamide Indapamide Indapamide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Amantadine may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Oxacillin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Pentoxifylline Pentoxifylline Pentoxifylline may decrease the excretion rate of Amantadine which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Pentamidine.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Amantadine which could result in a higher serum level.
Labetalol Labetalol Labetalol may decrease the excretion rate of Amantadine which could result in a higher serum level.
Auranofin Auranofin Amantadine may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Amantadine is combined with Leuprolide.
Gemfibrozil Gemfibrozil Amantadine may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Amantadine which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Amantadine which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Amantadine which could result in a higher serum level.
Pimozide Pimozide The therapeutic efficacy of Pimozide can be decreased when used in combination with Amantadine.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Amantadine which could result in a higher serum level.
Amiodarone Amiodarone The risk or severity of QTc prolongation can be increased when Amantadine is combined with Amiodarone.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Amantadine which could result in a higher serum level.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Amantadine.
Ciprofloxacin Ciprofloxacin The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ciprofloxacin.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Amantadine which could result in a higher serum level.
Fluoxetine Fluoxetine The risk or severity of serotonin syndrome can be increased when Fluoxetine is combined with Amantadine.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Nimodipine.
Clozapine Clozapine The therapeutic efficacy of Amantadine can be decreased when used in combination with Clozapine.
Estazolam Estazolam Amantadine may decrease the excretion rate of Estazolam which could result in a higher serum level.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Amantadine is combined with Ofloxacin.
Didanosine Didanosine Didanosine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Pentostatin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Clarithromycin Clarithromycin The risk or severity of QTc prolongation can be increased when Amantadine is combined with Clarithromycin.
Etodolac Etodolac Etodolac may decrease the excretion rate of Amantadine which could result in a higher serum level.
Felodipine Felodipine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Felodipine.
Fosinopril Fosinopril Fosinopril may decrease the excretion rate of Amantadine which could result in a higher serum level.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Amantadine which could result in a higher serum level.
Itraconazole Itraconazole The risk or severity of QTc prolongation can be increased when Amantadine is combined with Itraconazole.
Lisinopril Lisinopril Lisinopril may decrease the excretion rate of Amantadine which could result in a higher serum level.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Sotalol Sotalol The risk or severity of QTc prolongation can be increased when Amantadine is combined with Sotalol.
Bisoprolol Bisoprolol Bisoprolol may decrease the excretion rate of Amantadine which could result in a higher serum level.
Doxazosin Doxazosin The risk or severity of adverse effects can be increased when Doxazosin is combined with Amantadine.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Amantadine.
Cisapride Cisapride The risk or severity of QTc prolongation can be increased when Amantadine is combined with Cisapride.
Venlafaxine Venlafaxine The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Amantadine.
Nizatidine Nizatidine The therapeutic efficacy of Amantadine can be decreased when used in combination with Nizatidine.
Fluvoxamine Fluvoxamine The risk or severity of serotonin syndrome can be increased when Fluvoxamine is combined with Amantadine.
Nefazodone Nefazodone The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Nefazodone.
Lamotrigine Lamotrigine The serum concentration of Amantadine can be increased when it is combined with Lamotrigine.
Losartan Losartan The risk or severity of QTc prolongation can be increased when Losartan is combined with Amantadine.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Amantadine.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Amantadine.
Ifosfamide Injection Ifosfamide Injection Amantadine may decrease the excretion rate of Ifosfamide which could result in a higher serum level.
Nicardipine Nicardipine The risk or severity of QTc prolongation can be increased when Nicardipine is combined with Amantadine.
Bupropion Bupropion The excretion of Amantadine can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine Ticlopidine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Saquinavir Saquinavir The risk or severity of QTc prolongation can be increased when Amantadine is combined with Saquinavir.
Metformin Metformin The serum concentration of Amantadine can be increased when it is combined with Metformin.
Nisoldipine Nisoldipine Nisoldipine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Lamivudine Lamivudine The serum concentration of Lamivudine can be increased when it is combined with Amantadine.
Acarbose Acarbose Acarbose may decrease the excretion rate of Amantadine which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection Gemcitabine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Indinavir Indinavir The risk or severity of adverse effects can be increased when Indinavir is combined with Amantadine.
Ritonavir Ritonavir The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Amantadine.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Meropenem Injection Meropenem Injection Meropenem may decrease the excretion rate of Amantadine which could result in a higher serum level.
Clomipramine Clomipramine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Clomipramine.
Fosfomycin Fosfomycin Fosfomycin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Mirtazapine Mirtazapine Amantadine may increase the serotonergic activities of Mirtazapine.
Topiramate Topiramate Topiramate may decrease the excretion rate of Amantadine which could result in a higher serum level.
Pramipexole Pramipexole Amantadine may decrease the excretion rate of Pramipexole which could result in a higher serum level.
Donepezil Donepezil The therapeutic efficacy of Amantadine can be decreased when used in combination with Donepezil.
Nelfinavir Nelfinavir The risk or severity of adverse effects can be increased when Nelfinavir is combined with Amantadine.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Amantadine is combined with Azithromycin.
Loratadine Loratadine Amantadine may increase the anticholinergic activities of Loratadine.
Nilutamide Nilutamide Nilutamide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Flutamide Flutamide Flutamide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Selegiline Selegiline The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Selegiline.
Sertraline Sertraline The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Sertraline.
Propafenone Propafenone The risk or severity of QTc prolongation can be increased when Amantadine is combined with Propafenone.
Tamsulosin Tamsulosin Tamsulosin may decrease the excretion rate of Amantadine which could result in a higher serum level.
Quetiapine Quetiapine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Quetiapine.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Amantadine which could result in a higher serum level.
Cetirizine Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Amantadine.
Paroxetine Paroxetine The risk or severity of serotonin syndrome can be increased when Paroxetine is combined with Amantadine.
Tolcapone Tolcapone Tolcapone may decrease the excretion rate of Amantadine which could result in a higher serum level.
Citalopram Citalopram The risk or severity of QTc prolongation can be increased when Amantadine is combined with Citalopram.
Capecitabine Capecitabine Amantadine may decrease the excretion rate of Capecitabine which could result in a higher serum level.
Efavirenz Efavirenz The risk or severity of QTc prolongation can be increased when Amantadine is combined with Efavirenz.
Abacavir Abacavir Amantadine may decrease the excretion rate of Abacavir which could result in a higher serum level.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Amantadine which could result in a higher serum level.
Rosiglitazone Rosiglitazone Rosiglitazone may decrease the excretion rate of Amantadine which could result in a higher serum level.
Tolterodine Tolterodine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Tolterodine.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Amantadine which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Nateglinide Nateglinide Nateglinide may decrease the excretion rate of Amantadine which could result in a higher serum level.
Galantamine Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Amantadine.
Rabeprazole Rabeprazole Amantadine may decrease the excretion rate of Rabeprazole which could result in a higher serum level.

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