FDA-filed SPL labeling · retrieved through openFDA

Water

Water is used across multiple medical products as a diluent, irrigant, and vehicle for drug delivery, and is also found in ophthalmic eye wash products for cleansing and soothing irritated eyes.

Brand names Pur-washOpticlearOcufreshEye StreamSterile Water +11 more
Drug class ⓘ Insulin Analog
Rx/OTC Forms 8 Routes Ophthalmic · Intravenous · Intramuscular, Intravenous, Subcutaneous · Intramuscular; Intravenous; Subcutaneous +11
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 36 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveJan 20, 2026
Clinical labels in scope ⓘ36
AvailabilityRx/OTC
Earliest approval/marketing year ⓘ1965
FDA-listed product records ⓘ219
Boxed warningNone found in compared labels
How we combine label and product data →
✓No current FDA shortage listed · checked Sep 17, 2026 🚨Recall on record · 3
⭐ Water at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Water is the base ingredient in a range of medical products — from sterile diluents and irrigants used in clinical settings to insulin diluting solutions and over-the-counter eye washes. When it is part of an insulin product, the main risks to watch for are low blood sugar and drug interactions that affect blood sugar control. Always use the specific product exactly as directed by your prescriber or the product label.
How we write & review this content — our editorial policy →

📖 Water: Patient Information Guide

A plain-language walkthrough of Water — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Water is the active or vehicle ingredient in several different FDA-approved products, each with its own distinct approved use.

  • Sterile Water for Injection: used intravenously as a solvent or diluent for other drugs, or as a source of water for parenteral fluid replenishment after appropriate additives are added
  • Sterile Water for Injection (diluent use): used to dilute or dissolve drugs for intravenous, intramuscular, or subcutaneous injection, per each drug manufacturer's instructions
  • Sterile Water for Irrigation: used as an irrigating fluid or pharmaceutical aid, and to help prepare non-intravenously administered nutrient mixtures
  • Insulin Diluting Medium for Garzulys: used with Garzulys (a rapid-acting insulin aspart analog) to improve glycemic control in adults and children with diabetes mellitus
  • INSULIN DILUTING MEDIUM FOR Kirsty: used with Kirsty (a rapid-acting insulin aspart analog) to improve glycemic control in adults and children with diabetes mellitus
  • Crane Safety Eye Wash, Dynamic Eyewash with Eyecup, Easy Care First Aid Eyewash: ophthalmic use to cleanse the eye, remove loose foreign material, and relieve irritation or burning
  • Eyes Alive Eye Wash: ophthalmic use to flush the eye and relieve irritation, discomfort, burning, stinging, smarting, or itching, and to remove loose foreign material, air pollutants (such as smog or pollen), or chlorinated water
⚙️How it works▾

When water is used as part of insulin diluting products, it serves as the carrier for the active insulin. The insulin itself — an analog called insulin aspart — regulates blood sugar by prompting muscle and fat cells to take up glucose from the blood, reducing the liver's output of glucose, and supporting the body's ability to build and store proteins and fats. As a sterile diluent or irrigant, water works physically: it dissolves or dilutes medications for safe delivery, or mechanically flushes surfaces such as the eye or a body cavity.

💊How it's taken▾

How and when water-based products are used depends entirely on the specific product.

  • Sterile Water for Injection: given intravenously only after being properly mixed with drug additives — never administered as plain water by IV
  • Sterile Water for Irrigation: applied to body surfaces or cavities as directed; volume and rate depend on the procedure; not for IV use
  • Insulin diluting mediums (Garzulys, Kirsty): the diluted insulin is injected subcutaneously within 5–10 minutes before a meal, rotating sites; dose is set by your prescriber
  • Eye wash products: applied directly to the eye as needed; follow individual product label directions
🤒Side effects — in detail▾

Side effects depend on the specific product. With insulin aspart products that use water as a vehicle, the most common reactions include:

  • Low blood sugar (hypoglycemia) — the most frequent concern
  • Injection site reactions: redness, swelling, or itching
  • Skin changes at injection sites: lipoatrophy (skin depression) or lipohypertrophy (skin thickening)
  • Rash or generalized itching
  • Swelling (edema), particularly with intensified insulin therapy
  • Weight gain
  • Headache and nausea

Severe low blood sugar, serious allergic reactions (including anaphylaxis), and dangerously low potassium (hypokalemia) are rare but life-threatening and require immediate medical attention.

⚠️Warnings & precautions▾
  • Hypoglycemia (low blood sugar) is the most serious risk with insulin products. It can be life-threatening, cause seizures or unconsciousness, and impair your ability to drive or operate machinery. Risk increases with changes in dose, meals, activity, or other medications.
  • Sterile Water for Injection must never be given plain by IV — it is hypotonic (lacks salts) and can cause hemolysis (destruction of red blood cells). It must be made approximately isotonic by adding the proper solute before intravenous use.
  • Fluid and electrolyte overload is possible with large-volume intravenous fluid administration, potentially leading to pulmonary edema (fluid in the lungs) or dilution of blood salts.
  • Aluminum toxicity: some parenteral water preparations contain aluminum, which can accumulate to toxic levels in patients with impaired kidney function — especially premature newborns — and may cause nerve and bone damage.
  • Hypokalemia (low potassium): insulin can shift potassium into cells, potentially causing dangerous drops in blood potassium levels, leading to abnormal heart rhythms or respiratory problems.
  • Heart failure risk: using insulin together with thiazolidinedione (TZD) diabetes pills can cause fluid retention and worsen or trigger heart failure.
🔀What it interacts with▾

When water is part of an insulin aspart product, several drugs and substances can affect how well blood sugar is controlled:

  • Drugs that increase low-blood-sugar risk: other antidiabetic medications, ACE inhibitors, angiotensin II receptor blockers, disopyramide, fibrates, fluoxetine, MAO inhibitors, pentoxifylline, pramlintide, salicylates, octreotide, and sulfonamide antibiotics
  • Drugs that raise blood sugar and reduce insulin's effect: corticosteroids, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin, sympathomimetics (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones
  • Drugs with unpredictable effects on blood sugar: alcohol, beta-blockers, clonidine, lithium salts, and pentamidine (which may first cause low then high blood sugar)
  • Drugs that hide low-blood-sugar warning signs: beta-blockers, clonidine, guanethidine, and reserpine can mask symptoms like a racing heart, making it harder to notice a blood sugar drop

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾
  • Allergy: Garzulys is contraindicated in anyone allergic to insulin aspart or any of its ingredients
  • Active hypoglycemia: Garzulys must not be used during an episode of low blood sugar
  • Kidney impairment: patients with kidney disease may be at higher risk of low blood sugar and may need more frequent dose adjustments and blood sugar monitoring
  • Liver impairment: patients with liver disease may also need closer monitoring and possible dose adjustments
  • Pregnancy: poorly controlled diabetes in pregnancy increases risks for both mother and baby; insulin aspart products have been studied in the second trimester and have not been linked to major birth defects, but discuss all insulin use with your doctor
  • Breastfeeding: limited data exist on insulin aspart in breast milk; discuss the risks and benefits with your doctor
  • Children: Garzulys is approved for children aged 6 and older with diabetes mellitus
  • Older adults: use with caution; hypoglycemia risk may be higher and signs may be less obvious
  • Premature newborns: particularly vulnerable to aluminum toxicity from parenteral water preparations due to immature kidneys
🚑If you take too much▾

Overdose with treprostinil injection products (which use sterile diluent/water as a vehicle) can cause flushing, headache, low blood pressure, nausea, vomiting, and diarrhea — most cases resolve when the infusion is reduced or stopped. In rare serious cases, overdose has caused severe low blood pressure and, in one pediatric case involving a large accidental dose given through a central venous catheter, seizure-like activity and loss of consciousness — that patient recovered. If you suspect an overdose, seek emergency medical help immediately.

📡Pharmacodynamics — effects in the body▾

When insulin aspart (delivered via water-based injection products) is given subcutaneously, its peak blood-sugar-lowering effect occurs within 1 to 3 hours after injection, and the effect lasts about 3 to 5 hours. The exact timing can vary from person to person and even in the same person on different days, depending on injection site, physical activity, and other factors. When given intravenously, insulin aspart produces a blood sugar profile similar to regular human insulin.

🔬Pharmacokinetics — how your body processes it▾

For treprostinil injection products that use sterile diluent (water) as a vehicle: treprostinil is absorbed rapidly and almost completely after subcutaneous infusion, reaching steady-state levels in about 10 hours. It is heavily metabolized by the liver (primarily by the CYP2C8 enzyme) and eliminated mainly in urine. Its terminal half-life is approximately 4 hours. Patients with liver impairment clear the drug much more slowly — up to 80% less clearance — so they need lower starting doses and careful monitoring.

📦How to store it▾

Dispense in the original sealed carton with the enclosed Instructions for Use. Store unused NOVOLOG in a refrigerator between 2°C to 8°C (36°F to 46°F). Do not freeze NOVOLOG and do not use NOVOLOG if it has been frozen.

📄 Written from Water’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Water — the kind of thing our pharmacy team would talk through with you at the counter.

Why is 'water' listed as the active ingredient on my medicine? ▾
It can seem a little odd at first. In these products, sterile water plays the essential role of carrying or dissolving the actual active medication — like insulin — so it can be safely injected or infused. It also appears on its own as a medical-grade irrigating fluid used to flush body surfaces, or in eye wash products to rinse out irritants. The type of water used in medicines is highly purified and carefully manufactured — it's very different from tap water.
Is Sterile Water for Injection the same as the eye wash or the irrigation product? ▾
No — these are very different products that should never be used interchangeably. Sterile Water for Injection is used only as a diluent for other drugs given by needle, and it must always be mixed with an appropriate additive before IV use. Sterile Water for Irrigation is for flushing body surfaces and is not safe to inject by IV. Eye wash products are made specifically for rinsing the eye. Always use the exact product your doctor or the product label specifies.
My insulin vial says 'Insulin Diluting Medium' — what does that mean for me? ▾
The Insulin Diluting Medium for Garzulys and INSULIN DILUTING MEDIUM FOR Kirsty are used to dilute their specific insulin products when a lower concentration is needed — for example, in very young children or people who need very small doses. Your prescriber or pharmacist will tell you if and how to use a diluting medium with your insulin. You should never dilute insulin on your own without specific instructions.
What are the most important warning signs to watch for with insulin products that contain water as a vehicle? ▾
The biggest thing to watch for is low blood sugar (hypoglycemia). Signs include shakiness, sweating, confusion, a racing heart, or feeling very weak. Severe low blood sugar can cause seizures or loss of consciousness and is a medical emergency. Also watch for signs of a serious allergic reaction — hives, swelling of the face or throat, or trouble breathing — and call for help right away if any of those occur.
Can I use these eye wash products every day? ▾
Eye wash products like Crane Safety Eye Wash, Eyes Alive Eye Wash, and similar products are meant to flush and cleanse the eye — for example, after exposure to a foreign material, pollen, or chlorinated water. They can be used as needed according to their label directions. If your eye irritation is ongoing, severe, or not improving, check with your doctor rather than relying on an eye wash as a long-term solution.
Are there any medicines I should tell my doctor about before using an insulin product that contains this diluting medium? ▾
Yes — quite a few medications can affect how your insulin works. Some can push your blood sugar too low (like certain blood pressure medicines called ACE inhibitors, or antidepressants called MAO inhibitors), while others like steroids or some diuretics can push it too high. Alcohol is also tricky because it can unpredictably raise or lower blood sugar. Beta-blockers can hide the warning signs of a low. Make sure your doctor and pharmacist have a full list of everything you take.
Is Water available over the counter? ▾
Both — Water is sold both over the counter and by prescription, according to its FDA labeling. Lower strengths or certain forms are often available without a prescription, while higher strengths or specialized forms still require one. Ask your pharmacist which version is right for you.
When was Water first available? ▾
Water has been available in the United States since at least 1965, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Water? ▾
Water is supplied by 75 manufacturers listed in the FDA NDC Directory, including Siegfried Hameln GmbH, ICU Medical Inc., Henry Schein, Inc..

💬 Answers drafted from Water’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

🌿Drug & Supplement CheckerWater vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Water NDCs & costs 🅰️Browse Drugs A–ZLook up any medication

💊 How Water comes

Water is available in 8 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Injection

By injection · Into a muscle · Into a vein · Into the skin · Irrigation · On the skin · Under the skin
Brands Amaranthus Tuberculatus Pollen Bacteriostatic Water Diluent Insulin Diluting Medium for NovoLog Sterile Diluent for Remodulin Sterile Water
How this form is used
What it may be used for
  • Bacteriostatic Water and Sterile Water injection products: used only to dilute or dissolve drugs for intravenous, intramuscular, or subcutaneous injection per the drug manufacturer's instructions
  • Insulin Diluting Medium for Garzulys: used to dilute Garzulys (insulin aspart) to improve glycemic control in adults and children with diabetes mellitus
  • INSULIN DILUTING MEDIUM FOR Kirsty: used to dilute Kirsty (insulin aspart) to improve glycemic control in adults and children with diabetes mellitus
Important instructions
  • Bacteriostatic Water and Sterile Water: use only as a diluent per the instructions of the drug being reconstituted — never inject plain water intravenously without additives
  • Insulin Diluting Medium for Garzulys: used with Garzulys subcutaneous injection, given within 5–10 minutes before a meal; rotate injection sites to reduce skin changes
  • INSULIN DILUTING MEDIUM FOR Kirsty: used with Kirsty subcutaneous injection, given within 5–10 minutes before a meal; rotate injection sites within the same region
  • Follow your prescriber's instructions for dosing and administration of the specific insulin product
Available strengths 13 strengths
1 mg/mL 0.025 g/mL 0.05 g/mL 0.65 mL/0.65 mL 0.7 mL/mL 1 mL/mL
Show 7 more strengths Show fewer strengths
10 mL/10 mL 20 mL/20 mL 100 mL/100 mL 1000 mL/1000 mL 1000 [PNU]/mL 20000 [PNU]/mL 40000 [PNU]/mL
122 FDA-listed product records ⓘ

Eye drops

In the eye
Brands Advanced Eye Relief Eye Wash Eye Wash Eyewash EyS Eye Wash Green Guard First Aid Eye Wash Ocufresh Pur-wash Quality Choice Eye Wash
How this form is used
What it may be used for
  • Crane Safety Eye Wash: cleanses the eye to remove loose foreign material and relieve irritation and burning
  • Dynamic Eyewash with Eyecup and Easy Care First Aid Eyewash: cleanse the eye to help relieve irritation or burning by removing loose foreign material
  • Eyes Alive Eye Wash: flushes the eye to relieve irritation, discomfort, burning, stinging, smarting, or itching, and to remove loose foreign material, air pollutants, or chlorinated water
Important instructions
  • Apply directly to the eye as needed to flush and cleanse
  • Follow the directions on the individual product label for proper use
Available strengths 14 strengths
0.983 mg/mL 980 mg/mL 991 mg/mL 99.05 g/100 mL 929 g/946 mL 0.98 mL/mL
Show 8 more strengths Show fewer strengths
0.988 mL/mL 14.85 mL/15 mL 70 mL/100 mL 92.2 L/100 L 95.1 mL/100 mL 98.3 mL/100 mL 98.4 mL/100 mL 99.05 mL/100 mL
60 FDA-listed product records ⓘ

Other oral form

Irrigation
Brands Sterile Water
How this form is used
What it may be used for
  • Sterile Water for Irrigation: used as an irrigating fluid or pharmaceutical aid
  • Sterile Water for Irrigation: may be used as an adjunct in preparing non-intravenously administered nutrient mixtures
Important instructions
  • Sterile Water for Irrigation: for irrigation use only — not for intravenous injection or infusion
  • Sterile Water for Irrigation: volume and rate of use depend on the procedure; follow physician's directions
Available strengths 2 strengths
1 mL/mL 100 mL/100 mL
15 FDA-listed product records ⓘ

Topical solution

On the skin
Brands Eye Wash
How this form is used
What it may be used for
  • Eye Wash (topical): cleanses the eye to help relieve irritation or burning by removing loose foreign material
Important instructions
  • Eye Wash (topical): apply to the eye as directed on the product label to flush and cleanse
Available strengths 2 strengths
991 mg/mL 99.1 mL/100 mL
5 FDA-listed product records ⓘ

Sublingual tablet

Under the tongue
Available strengths 1 strength
30 [hp_X]/mL
2 FDA-listed product records ⓘ

Topical spray

On the skin
Available strengths 1 strength
0.008 mg/100 mL
1 FDA-listed product record ⓘ

Vaginal insert

Rectal · Vaginal
Available strengths 1 strength
6.7 g/200 mL
1 FDA-listed product record ⓘ

📊 Water across the U.S. market

How Water appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

8
Dose forms ⓘ
75
Manufacturers
40
Brand names
219
FDA-listed product records ⓘ
1965
First marketed ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Siegfried Hameln GmbH11%
ICU Medical Inc.8%
Henry Schein, Inc.6%
Niagara Pharmaceuticals Inc.5%
ALK-Abello, Inc.5%
Unifirst First Aid Corporation3%
Other makers61%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Water is used

A general measure of how commonly Water is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Water is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

204,877
Medicaid prescriptions filled (Q1–Q4 2025)
$45.5M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Water prescribed? Of the 1,594 medications we measure, Water ranks #390 by Medicaid prescriptions — more than 76% of them.

Where Water ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #390 of 1,594
#385 Icosapent Ethyl 211,612 Rx #386 Amantadine 210,143 Rx #387 Valsartan and Hydrochl... 208,319 Rx #388 Fremanezumab-vfrm Inje... 205,598 Rx #389 Solifenacin 205,369 Rx #390 Water 204,877 Rx #391 Metformin / Sitaglipti... 203,107 Rx #392 Silver Sulfadiazine 202,248 Rx #393 Levalbuterol Oral Inha... 197,722 Rx #394 Hydromorphone Injectio... 195,712 Rx #395 Chlorpromazine 195,153 Rx

Utilization by Water product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 1000 mg/mL irrigation solution is the most-dispensed Water product — about 40% of these Medicaid prescriptions.

water 1000 MG/ML Irrigation Solution Most dispensed

82,279 Medicaid prescriptions (Q1–Q4 2025) 40% of Water prescriptions shown $2.6M gross reimbursement (before rebates) ≈ $32 per prescription (gross)

Summed across the 10 of 40 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 150985

water 991 MG/ML Ophthalmic Irrigation Solution

30 Medicaid prescriptions (Q1–Q4 2025) <1% of Water prescriptions shown $105 gross reimbursement (before rebates) ≈ $3.51 per prescription (gross)

Summed across the 2 of 30 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1053429

Other Water products — combination packs and listings not yet matched to a specific clinical product (kept visible so every prescription is accounted for)

122,568 Medicaid prescriptions (Q1–Q4 2025) 60% of Water prescriptions shown $42.9M gross reimbursement (before rebates) ≈ $350 per prescription (gross)

Summed across the 26 of 164 listed NDC products with Medicaid activity.

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Water, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 38 of 234 listed Water NDCs with Medicaid activity.

🔍 Compare Water products

A representative set of FDA-listed product records for Water — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 200 of 219 products — FDA National Drug Code Directory. See every product, package size and price: browse all 219 Water NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Water RxCUI 11295 3 dose forms · 13 strengths
  1. Dose form (SCDF) Inhalation Solution RxCUI 2108561 No current FDA listing
    Clinical drug / strength (SCD) 1000 MG/ML RxCUI 204918
  2. Dose form (SCDF) Irrigation Solution RxCUI 379002 In current FDA listings
    Clinical drug / strength (SCD) 1000 MG/ML RxCUI 150985

Look up RxCUI 11295 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Pur-wash Opticlear Ocufresh Eye Stream Sterile Water Eye Wash Amaranthus Tuberculatus Pollen Bacteriostatic Water Sterile Diluent for Remodulin Diluent Green Guard First Aid Eye Wash Advanced Eye Relief Eye Wash Quality Choice Eye Wash Insulin Diluting Medium for NovoLog EyS Eye Wash Eyewash

🏭 Manufacturers & labelers

Siegfried Hameln GmbH 19 ICU Medical Inc. 14 Henry Schein, Inc. 11 Niagara Pharmaceuticals Inc. 9 ALK-Abello, Inc. 8 Unifirst First Aid Corporation 6 Fresenius Kabi USA, LLC 6 Baxter Healthcare Corporation 6 Baxter Healthcare Company 6 Hospira, Inc. 5 Cardinal Health 107, LLC 5 B. Braun Medical Inc. 5 Medical Purchasing Solutions, LLC 5 Honeywell Safety Products USA, Inc 4 United Therapeutics Corporation 4 Patheon Manufacturing Services LLC 3 Hikma Pharmaceuticals USA Inc. 3 Eyes-Plus LLC 3 Chain Drug Marketing Assoc., Inc. 3 Optics Laboratory Inc. 3 Novo Nordisk 3 Bausch & Lomb Incorporated 3 Isomedix Operations Inc. 3 Becton Dickinson and Company 3

…and 16 more on the FDA NDC directory.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Jan 20, 2026
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Water.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Water after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
36
NDC products indexed
219
Distinct labelers/manufacturers represented
75
Linked representative label ⓘ
Biocon Biologics Inc.
Linked label effective
Jan 20, 2026
Composite sections available
25
Linked SPL Set ID
3db1d482-7e1f-aec6-79ef-3f305b4d8277
Linked SPL Document ID
2448d65b-6ba8-f4da-792b-6c2a3f6577fb
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 36 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Biocon Biologics Inc. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.