Bay Leaf - ActoPlus Met (pioglitazone, metformin) Interaction
Herbal: Bay Leaf
Also Known As: Laurus nobilis, Bay, Bay Laurel, Bay Leaf, Bay Tree, Daphne, Grecian Laurel, Laurel, Laurel Común, Laurier d'Apollon, Laurier Noble, Laurier-Sauce, Laurier Vrai, Mediterranean Bay, Noble Laurel, Roman Laurel, Sweet Bay, Sweet Laurel, True Bay, True Laurel
Drug: pioglitazone, metformin
Brand names:
ActoPlus Met
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
pioglitazone, metformin is classified as belonging to the following category: Antidiabetes Drugs
Concomitant use of bay leaf with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical research shows that bay leaf can lower blood glucose levels in patients with diabetes who are already taking antidiabetes medication. Advise patients to monitor glucose levels closely. Dose adjustments may be necessary.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Khan, A., Zaman, G., and Anderson, R. A. Bay leaves improve glucose and lipid profile of people with type 2 diabetes. J Clin Biochem.Nutr. 2009;44(1):52-56.
Bay Leaf Overview
Bay leaf is the aromatic leaf of the bay laurel tree. It is commonly used in cooking as a flavoring agent, and is known for its distinctive, slightly bitter taste. It has also been used in folk medicine for a variety of ailments and conditions, including arthritis, asthma, cardiovascular disease (CVD), colds, diabetes, diarrhea, dysmenorrhea, and epilepsy.
Bay Leaf - More Interactions
Bay Leaf interacts with 332 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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