Beer - Addyi (Flibanserin) Interaction
Herbal: Beer
Drug: Flibanserin
Brand names:
Addyi
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Flibanserin is classified as belonging to the following category: Cns Depressants
Concomitant use may increase sedative and other adverse effects.
Concomitant use of alcohol with CNS depressants can increase sedative and other adverse effects, potentially through inhibition of the metabolism of certain CNS depressants.
Interaction Rating
Likelihood of Occurrence
LikelyWell-controlled human studies have demonstrated the likely existence of this interaction
References
- Fraser AG. Pharmacokinetic interactions between alcohol and other drugs. Clin Pharmacokinet 1997;33:79-90.
Interaction Details
Flibanserin is classified as belonging to the following category: Flibanserin (Addyi)
Concomitant use increases the risk of severe hypotension and syncope.
Alcohol use is contraindicated in patients taking flibanserin due to the risk of severe hypotension and syncope.
Interaction Rating
Likelihood of Occurrence
ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
References
- Addyi (flibanserin) prescribing information. Sprout Pharmaceuticals, Inc. Raleigh, NC, September 2021. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/022526s010lbl.pdf
Beer Overview
Beer is a popular beverage made from fermented sugars derived from starch-based materials, such as malted barley. Beer contains minerals like magnesium, potassium, selenium, and B vitamins, as well as flavonoids, especially in darker beers. These flavonoids, along with other compounds like xanthohumol from hops, have been studied for potential health benefits.
Some research suggests that beer, particularly its polyphenolic compounds, may have antioxidant effects, which could contribute to protection against atherosclerotic cardiovascular disease. Moderate beer consumption has also been linked to potential benefits for bone health, cardiovascular health, and even anticancer effects, although these effects can vary based on individual factors and consumption patterns. However, excessive alcohol consumption, including beer, can lead to negative health effects such as increased risk of cardiovascular disease, hypertension, and other conditions.
Flibanserin Overview
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Flibanserin is used to treat women with hypoactive sexual desire disorder (HSDD; a low sexual desire that causes distress or interpersonal difficulty) who have not experienced menopause (change of life; the end of monthly menstrual periods). Flibanserin should not be used for the treatment of HSDD in women who have gone through menopause or in men or to improve sexual performance. Flibanserin is in a class of medications called a serotonin receptor 1A agonist/serotonin receptor 2A antagonist. It works by changing the activity of serotonin and other natural substances in the brain.
Beer - More Interactions
Beer interacts with 895 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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