Boswellia Serrata - Lamictal (Lamotrigine) Interaction
Herbal: Boswellia Serrata
Also Known As: Boswellia serrata, Arbre à Oliban Indien, Boswella, Boswellin, Boswellin Serrata Resin, Encens Indien, Gajabhakshya, Indian Frankincense, Oliban Indien, Salai Guggal, Salai Guggul, Sallaki Guggul, Shallaki
Drug: Lamotrigine
Brand names:
Lamictal
![](https://hellopharmacist.nyc3.digitaloceanspaces.com/images/OBrXo3ni0aNq6p1xr8LXWNogoaVtCExyhTj9MEzw.jpg)
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 23, 2024
Interaction Details
There were no interactions found between Lamotrigine and Boswellia Serrata. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
No interaction has been noted between Boswellia and the drug in question on this interaction check.
In terms of other interactions, Boswellia serrata has been shown in laboratory studies to mildly inhibit several enzymes involved in drug metabolism, including CYP1A2, CYP2C19, CYP2C9, CYP2D6, and CYP3A4. This inhibition may increase the levels of drugs metabolized by these enzymes, potentially leading to adverse effects.
However, it is important to note that this inhibition has only been seen in a lab setting, and has not been reported in humans. Whether or not Boswellia supplements have clinically significant drug interactions due to the effects on the above enzymes isn't well known. In most cases, it appears unlikely that these interactions would be clinically significant as there is a lack of reports of problems being caused in humans.
In addition, Boswellia serrata may interact with immunosuppressive drugs.
Studies show that Boswellia may help reduce the activity of some cells involved in autoimmune diseases. This could lead to a decrease in the production of antibodies and certain immune cells. However, other studies have found that certain components of Boswellia serrata may actually stimulate the immune system in certain situations. More research is needed to better understand the effect of Boswellia on immunosuppressive drugs.
- Dr. Brian Staiger, PharmDBoswellia Serrata Overview
![Boswellia Serrata](https://hellopharmacist.nyc3.digitaloceanspaces.com/images/herbals/width_250/HtVnjfhP1bSZWJn6bePIfZr92PcU5aBJoLBTUQX8.jpg)
Lamotrigine Overview
-
Lamotrigine extended-release (long-acting) tablets are used with other medications to treat certain types of seizures in patients who have epilepsy. All types of lamotrigine tablets (tablets, orally disintegrating tablets, and chewable tablets) other than the extended-release tablets are used alone or with other medications to treat seizures in people who have epilepsy or Lennox-Gastaut syndrome (a disorder that causes seizures and often causes developmental delays). All types of lamotrigine tablets other than the extended-release tablets are also used to increase the time between episodes of depression, mania (frenzied or abnormally excited mood), and other abnormal moods in patients with bipolar I disorder (manic-depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Lamotrigine has not been shown to be effective when people experience the actual episodes of depression or mania, so other medications must be used to help people recover from these episodes. Lamotrigine is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain.
Boswellia Serrata - More Interactions
Boswellia Serrata interacts with 920 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
Return to the main herbal interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.