Cabbage - Premarin (Conjugated Estrogens) Interaction
Herbal: Cabbage
Also Known As: Brassica oleracea, Cabbage Leaf, Chou, Chou Blanc, Chou Commun, Chou Rouge, Chou Vert, Col, Green Cabbage, Headed Cabbage, Purple Cabbage, Red Cabbage, Repollo, Vitamin U, Vitamine U, White Cabbage
Drug: Conjugated Estrogens
Brand names:
Premarin, Cenestin, Enjuvia, Premarin Vaginal Cream
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 09, 2024
Interaction Details
Conjugated Estrogens is classified as belonging to the following category: Glucuronidated Drugs
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
A small clinical study shows that daily consumption of cabbage and Brussels sprout decreases levels of some drugs metabolized through glucuronide conjugation.
Interaction Rating
Likelihood of Occurrence
ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
References
- Pantuck EJ, Pantuck CB, Anderson KE, et al. Effect of brussels sprouts and cabbage on drug conjugation. Clin Pharmacol Ther 1984;35:161-9.
Cabbage Overview
Cabbage is a leafy, green vegetable that belongs to the Cruciferae family, which also includes broccoli, kale, and Brussels sprouts. There are several different varieties of cabbage, including green, red, and Napa (Chinese) cabbage, which vary in size, shape, and color. Cabbage is high in a variety of vitamins and minerals, including vitamin C, vitamin K, and folate. It is also a good source of dietary fiber and contains antioxidants. It is consumed as a low-calorie health food. It has been used in traditional medicine for its purported anti-inflammatory effects and for certain conditions, such as gastrointestinal disorders and breast engorgement.
Conjugated Estrogens Overview
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The estradiol cypionate and estradiol valerate forms of estrogen injection are used to treat hot flushes (hot flashes; sudden strong feelings of heat and sweating) and/or vaginal dryness, itching, and burning in women who are experiencing menopause (change of life; the end of monthly menstrual periods). However, women who need a medication only to treat vaginal dryness, itching, or burning should consider a different treatment. These forms of estrogen injection are also sometimes used to treat the symptoms of low estrogen in young women who do not produce enough estrogen naturally. The estradiol valerate form of estrogen injection is also sometimes used to relieve the symptoms of certain types of prostate (a male reproductive organ) cancer. The conjugated estrogens form of estrogen injection is used to treat abnormal vaginal bleeding that a doctor has decided is caused only by a problem with the amounts of certain hormones in the body. Estrogen injection is in a class of medications called hormones. It works by replacing estrogen that is normally produced by the body.
Cabbage - More Interactions
Cabbage interacts with 320 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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