Cinchona - Tysabri (Natalizumab) Interaction
Herbal: Cinchona
Also Known As: Cinchona calisaya, Arbol de la Quina, Bois aux Fièvres, Calisaya Bark, Cascarilla, China Bark, Chinarinde, Chinarindenbaum, Chininbaum, Cinchonine, Écorce du Pérou, Écorce de Quina, Écorce de Quinquina Rouge, Fever Tree, Fieberrinde, Fieberrindenbaum, Jesuit's Bark
Drug: Natalizumab
Brand names:
Tysabri
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Natalizumab and Cinchona. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Cinchona Overview
Cinchona is a genus of flowering plants belonging to the Rubiaceae family. It contains around 25 different species and is native to the Andes mountains of South America. One of the most well-known species is Cinchona calisaya. The bark of cinchona is a source of quinine, an alkaloid that has been used for centuries to treat malaria. Cinchona bark is also used in traditional medicine for a variety of other ailments, including muscle cramps, restless legs, fever, arthritis, and digestive disorders. As Cinchona contains quinine, it is sometimes used as a flavoring on tonic water and alcoholic drinks. Cinchona bark has been shown to contain, on average, 5% to 15% quinoline alkaloids.
Natalizumab Overview
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Natalizumab is used to prevent episodes of symptoms and slow the worsening of disability in adults who have relapsing forms of multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control), including:
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clinically isolated syndrome (CIS; first nerve symptom episode that lasts at least 24 hours),
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relapsing-remitting disease (course of disease where symptoms flare up from time to time),
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active secondary progressive disease (later stage of disease with continuous worsening of symptoms.)
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Natalizumab is also used to treat and prevent episodes of symptoms in adults who have Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever) who have not been helped by other medications or who cannot take other medications. Natalizumab is in a class of medications called monoclonal antibodies. It works by stopping certain cells of the immune system from reaching the brain and spinal cord or digestive tract and causing damage.
Cinchona - More Interactions
Cinchona interacts with 481 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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