Coca - Steglatro (Ertugliflozin) Interaction

Interaction Details

Ertugliflozin is classified as belonging to the following category: Antidiabetes Drugs

Theoretically, coca might reduce the effects of antidiabetes drugs.
Some clinical research suggests that coca and the coca constituent cocaine have hyperglycemic effects. Theoretically, concomitant use of coca with antidiabetes drugs might interfere with glucose control and decrease the effectiveness of antidiabetes drugs.

Interaction Rating

Likelihood of Occurrence

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

• Favier R, Caceres E, Guillon L, et al. Coca chewing for exercise: hormonal and metabolic responses of nonhabitual chewers. J Appl Physiol 1996;81:1901-7..
• Galarza Guzman M, Penaloza Imana R, Echalar Afcha L, et al. Effects of coca chewing on glucose tolerance test. Medicina (B Aires) 1997;57(3):261-4.
• Spielvogel, H., Caceres, E., Koubi, H., Sempore, B., Sauvain, M., and Favier, R. Effects of coca chewing on metabolic and hormonal changes during graded incremental exercise to maximum. J.Appl.Physiol 1996;80(2):643-649.
• Favier, R., Caceres, E., Koubi, H., Sempore, B., Sauvain, M., and Spielvogel, H. Effects of coca chewing on hormonal and metabolic responses during prolonged submaximal exercise. J.Appl.Physiol 1996;80(2):650-655.

Ertugliflozin Overview

• Ertugliflozin is used along with diet and exercise, and sometimes with other medications, to lower blood sugar levels in people with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Ertugliflozin is in a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It lowers blood sugar by causing the kidneys to get rid of more glucose in the urine. Ertugliflozin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated).

• Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Coca - More Interactions

Coca interacts with 253 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.