Concerns With Metoprolol Causing Alopecia (Hair Loss)

In our latest question and answer, the pharmacist discusses a concern a reader has about metoprolol causing hair loss.

3 min read Updated Jun 2026 Read by 2,438 people
Concerns With Metoprolol Causing Alopecia (Hair Loss)
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CAZ asked

I am on amlodipine for blood pressure. It caused heart palpitations, so they added metoprolol. Around the time I was put on the metoprolol (which did help the palpitations), my hair fell out - all of it. (By the way, I am female.) So now I'm on oral and topical minoxidil. After eliminating everything else besides just bad luck, my dermatologist agreed that the metoprolol could be causing the hair loss. I was wondering if you'd have a suggested medication change, and if so, to what?

Apr 14, 2024
The quick answer
  • Hair loss is a rarely reported side effect of metoprolol that has been documented after the drug came to market. The hair loss caused by metoprolol appears to be reversible, so it may resolve if you stop taking the medication. Some beta-blockers like nebivolol do not list hair loss as a potential side effect, so discussing alternative options with your doctor may be worth considering.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.

Answer

I'm sorry to hear about the hair loss you are experiencing with metoprolol!

Like you said, it may just be bad luck, but hair loss with metoprolol is a rarely reported side effect. It's certainly not common and has only been seen in post-marketing surveillance (i.e., after the drug has come to market). According to the prescribing information for Toprol (metoprolol):

There have been rare reports of reversible alopecia, agranulocytosis, and dry eyes.
Toprol Prescribing Information

Metoprolol belongs to a class of drugs known as beta-blockers, and alopecia is listed as a potential side effect for most of them. For example, a similar statement appears in the prescribing information for atenolol, a different beta blocker:

During postmarketing experience with TENORMIN [atenolol], the following have been reported in temporal relationship to the use of the drug: elevated liver enzymes and/or bilirubin, hallucinations, headache, impotence, Peyronie's disease, postural hypotension which may be associated with syncope, psoriasiform rash or exacerbation of psoriasis, psychoses, purpura, reversible alopecia...
Atenolol Prescribing Information

Alternative Beta-Blockers To Avoid Hair Loss

You stated in your question you are taking metoprolol to treat palpitations. Although palpitations are usually managed as part of a larger condition, such as an arrhythmia, beta-blockers like metoprolol can specifically address palpitations by regulating the heart rate and reducing the sensation of them.

It's unclear if you are taking a beta-blocker solely for palpitations or for another condition. Sometimes, a specific beta-blocker is recommended for a particular condition. For this answer, I'll consider all beta-blockers as potential options for you.

As mentioned, most beta-blockers, including metoprolol, list alopecia as a potential side effect.

It's unknown if one beta-blocker is more likely than another to cause alopecia. It likely depends on an individual's response to a specific beta-blocker so it's tough to make a definitive recommendation.

There are a few beta-blockers similar to metoprolol that do not list alopecia as a side effect in their prescribing information, such as nebivolol (generic for Bystolic). You could discuss with your doctor if a different beta-blocker, like nebivolol, could be an option for you.

Additionally, propranolol, although it does list alopecia as a potential side effect, is commonly used for palpitations on an as-needed basis. It may be worth discussing with your doctor whether you need a daily medication to treat your palpitations or if taking something just on an as needed basis when symptoms occur would be sufficient. Taking a medication less frequently may reduce the severity of the hair loss you are experiencing.

The good news is that alopecia due to beta-blocker use appears to be reversible based on clinical studies, so if you discontinue metoprolol, it's likely your alopecia will start resolving.

As a final note in this answer, here is a list of beta-blockers that are most similar to metoprolol, which could be options for you:

  • Atenolol
  • Betaxolol
  • Bisoprolol
  • Nebivolol

I say these are most similar as they are all classified as 'cardio-selective' beta-blockers, meaning they preferentially interact with beta-1-adrenergic receptors, which are primarily found in the heart. Other beta blockers affect a broader range of receptors.

Final Words

I hope you found this information helpful! Please reach out if you have any more questions.

References & sources
  1. Bystolic Prescribing Information — AccessFDA
  2. Tenormin Prescribing Information — AccessFDA
  3. ZEBETA Prescribing Information — AccessFDA
  4. Inderal Prescribing Information — AccessFDA
  5. Metoprolol Succinate Prescribing Information — AccessFDA
  6. Metoprolol and alopecia — PubMed
  7. [Drug-induced alopecia: review of the literature] — PubMed
Glossary — Terms in This Answer
Alopecia
Hair loss, which may be temporary or permanent depending on the cause.
Beta-blockers
A class of medications that reduce heart rate and blood pressure by blocking certain nerve signals to the heart.
Post-marketing surveillance
The monitoring of drug safety and side effects that occurs after a medication has been approved and released to the public.
Agranulocytosis
A serious condition where the body stops producing enough white blood cells, making it difficult to fight infections.
Arrhythmia
An irregular heartbeat or abnormal heart rhythm.
Palpitations
A sensation of feeling your heart beating unusually fast, hard, or irregularly.
Cardio-selective beta-blockers
Beta-blocking medications that primarily affect the heart rather than other parts of the body.
Beta-1-adrenergic receptors
Specific sites on heart cells that respond to nerve signals controlling heart rate and force of contraction.
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Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

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