Conjugated Linoleic Acid (cla) - Guanethidine Monosulfate Interaction
Herbal: Conjugated Linoleic Acid (cla)
Drug: Guanethidine Monosulfate
Brand names:
Ismelin, Isimil
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Guanethidine Monosulfate is classified as belonging to the following category: Antihypertensive Drugs
Theoretically, taking CLA with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that a particular form of CLA reduces systolic blood pressure. Also, some clinical research shows that CLA enhances the blood pressure-lowering effects of ramipril, an antihypertensive drug.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Nagao, K., Inoue, N., Wang, Y. M., Hirata, J., Shimada, Y., Nagao, T., Matsui, T., and Yanagita, T. The 10trans,12cis isomer of conjugated linoleic acid suppresses the development of hypertension in Otsuka Long-Evans Tokushima fatty rats. Biochem.Biophys
- Zhao, W. S., Zhai, J. J., Wang, Y. H., Xie, P. S., Yin, X. J., Li, L. X., and Cheng, K. L. Conjugated linoleic acid supplementation enhances antihypertensive effect of ramipril in Chinese patients with obesity-related hypertension. Am.J Hypertens. 2009;2
Conjugated Linoleic Acid (cla) Overview
Conjugated linoleic acid (CLA) is a type of polyunsaturated fatty acid found in small amounts in the meat and dairy products of certain animals. It is also found in small amounts in some plant-based oils, such as safflower and sunflower oil. The majority of dietary supplements utilize CLA obtained from safflower oil.
CLA has been the subject of numerous scientific studies and has been suggested to have a number of potential health benefits, including weight loss, improving body composition, reducing inflammation, and decreasing the risk of certain types of cancer. However, the evidence for these potential benefits is mixed and more research is needed to fully understand the effects of CLA on health.
Conjugated Linoleic Acid (cla) - More Interactions
Conjugated Linoleic Acid (cla) interacts with 283 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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